• 한국임상보건과학회지
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• 제7권1호
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• pp.1232-1237
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• 2019

Purpose. In this study, two types of soft contact lenses with different materials were selected to compare the time of tear film destruction and high order aberrations before and after wearing. Methods. Thirty patients (60 eyes) in their 20s were included in this study. Two lenses with different materials, Group 4 (Etafilcon A) and Group 5 (Narafilcon A) were selected. Using aberration analyzer and keratometry, high-order aberration and tear film test (NIF-BUT, NIAvg-BUT) were performed before and after wearing. Results. When comparing the higher aberrations of the Etafilcon A and Narafilcon A lenses, the higher aberrations of the Narafilcon A lens were higher overall. For the initial tear film break-up time (NIF-BUT) after wearing, the Etafilcon A lens was reduced by 4.0 seconds and the Narafilcon A lens increased by 0.6 seconds. For the mean tear film break-up time (NIAvg-BUT) after wearing, the Etafilcon A lens decreased by 2.4 seconds and the Narafilcon A lens increased by 1.7 seconds. Conclusions. NIF-BUT and NIAvg-BUT of Narafilcon A lens were increased. The lens with relatively low water content and higher oxygen permeability than the lens with high water content has relatively less tear evaporation, which means that the time of destruction of the tear film is increased.

• 대한시과학회지
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• 제20권4호
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• pp.497-504
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• 2018

목적 : 백내장 환자를 대상으로 수술 전과 후의 안구표면의 온도변화 양상을 열화상카메라의 서모그래피를 이용하여 연구 하고자 하였다. 방법 : 본 연구는 백내장 수술을 받은 환자 50-79세까지 75명 75안의 환자 군을 대상으로 하였다. 과거에 굴절교정수술, 각막관련 수술을 받은 자와 콘택트렌즈를 사용하는 자, 눈물관 이상자, 전신질환 치료 약물을 복용하는 자 등 눈물분비와 눈물막에 영향을 줄 수 있는 자는 연구 대상자에서 제외하였고 눈물막파괴시간 검사(Tear Break Up Time, BUT), 쉬르머 검사(Schirmer's Test), 맥모니테스트(Mcmonnies questionnaire)를 시행한 후 열화상카메라(Cox CX series, Answer., Korea)를 이용하여 안구표면의 온도변화를 실시간으로 측정하였다. 결과 : 전체 대상자의 술 전 안구표면 온도는 $35.20{\pm}0.54^{\circ}C$이었고 술 후에는 $35.30{\pm}0.53^{\circ}C$로 표면온도가 상승하였으나 유의한 차이를 보이지 않았다. 안구표면 온도변화는 술전에서 $-0.12{\pm}0.08{\Delta}$ ($^{\circ}C/sec$)에서 술 후 $-0.18{\pm}0.07{\Delta}$ ($^{\circ}C/sec$)로 통계학적으로 유의한 결과를 나타냈다. 연령 별 비교에서는, 50 대군은 백내장 술 전 대상자의 안구표면 온도변화가 $-0.14{\pm}0.09{\Delta}$ ($^{\circ}C/sec$)에서 $-0.19{\pm}0.05{\Delta}$ ($^{\circ}C/sec$)으로 나타났고 60 대군에서는 $-0.12{\pm}0.08{\Delta}$ ($^{\circ}C/sec$)에서 $-0.15{\pm}0.07{\Delta}$ ($^{\circ}C/sec$)으로 나타났으며 70 대군에서는 술 전 대상자의 안구표면 온도변화는 $-0.12{\pm}0.08{\Delta}$($^{\circ}C/sec$)에서 $-0.18{\pm}0.07{\Delta}$($^{\circ}C/sec$)으로 전 연령에서 모두 유의한 안구표면 온도변화를 보였다. 결론 : 백내장 술 후에는 안구건조증 평가지표가 모두 감소하였고 안구표면 온도변화가 유의함을 보였다. 안구표면의 서모그래피 기술은 비침습적으로 안구건조증을 평가하는데 용이하였고 객관적으로 수치화할 수 있는 장점이 있어 다양한 안구건조증 연구에 활용 될 것으로 기대된다.

• 한국안광학회지
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• 제12권2호
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• pp.1-12
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• 2007

본 연구는 학동기 아동에서 근시교정용 콘택트렌즈인 역기하학 콘택트렌즈(RGL, reverse geometry contact lens)에 대한 근시교정 효과 및 안전성을 평가하는데 있다. 본 연구에서는 2004년 3월부터 2005년 7월 사이에 근시굴절교정술을 목적으로 역기하학렌즈를 처방 받은 7세부터 18세사이의 학동기 환자 중 착용 후 3개월 이상 추적관찰이 가능했던 중등도 이하의 근시(-1.00~-5.00 D(Diopter))를 갖는 남녀 53명 106안을 연구대상으로 하였다. 렌즈처방을 위한 검사로는 세극동 현미경, BUT(Break Up Time), 직상검안경, 검영기, 나안시력, 최대 교정시력, 자동굴절검사, 각막곡률측정, 각막지형도검사를 착용 전과 착용 후 1일, 1주일, 2주일, 1개월, 2개월, 3개월 째 각각 시행하여 근시교정 효과와 합병증 발생 여부를 알아보았다. 그 결과는 다음과 같다. 렌즈 착용 전 평균 나안시력은 $0.0938{\pm}0.378$에서 착용 후 1일에 $0.3136{\pm}0.283$이었고, 1주에는 $0.7925{\pm}0.301$으로 급격한 시력향상을 보였으며 2주후부터는 약간씩이었지만 계속되는 추이를 보였다(p<0.01). 각막지형도검사 상 편심율은 역기하학 렌즈 착용 전 평균 $0.548{\pm}0.099$에서 착용 후 3개월에는 $-0.257{\pm}0.283$(t=2.321, p=0.022)으로 감소하였다. 렌즈 착용 후 1일부터 2개월 사이에 급격한 편심율 감소를 보였으며(p<0.01) 2개월 후부터는 약간의 감소를 보였다(p<0.05). 이상의 결과로부터 역기하학 렌즈는 중동도 이하의 근시를 가진 환자에 있어 일시적으로 굴절이상을 교정하고 근시진행을 조절하는데 매우 유용한 방법임을 알 수 있었다. 부작용은 상대적으로 미미하였으나 장기적으로 눈 건강에 미치는 영향에 관해서는 추가 연구가 더 필요하리라 생각된다. 렌즈의 처방은 편심율(eccentricity)과 각막지형도의 분포도를 고려한 주문제작 피팅법이 매우 높은 성공률을 보였다.

• 한방안이비인후피부과학회지
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• 제25권2호
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• pp.61-67
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• 2012

Objective : The endpoint of this trial is to verify therapeutical availability of conventional western eyedrops combined with acupuncture treatment by means of BUT(tear film break-up time), Schirmer's test, which have been considered to be typical methods for diagnosing dry eye syndrome. Methods : The subjects of this trial included the outpatients who had been diagnosed with dry eye syndrome in Pusan national university hospital and underwent acupuncture treatment from March 2011 to April 2011. They received acupuncture treatment once a week, three times while constantly using Restasis or artificial tears. We collated and analyzed the outcome data of Schirmer's test and BUT conducted at the beginning of this trial and three times more after each acupuncture treatments. Acupoints, such as, Chanjuk(BL2), Eoryo, Sajukgong(TE23), Taeyang, Sabaek(ST2), limited around both eyes were selected based on their clinical effects referring to medical books. Results : 1. From BUT test results, Restasis and acupuncture combined group showed statistically significant difference, however, artificial tears and acupuncture combined group showed difference only between before and after the treatment, which is not statistically significant. 2. From Schirmer's test results, Restasis and acupuncture combined group showed statistically significant difference, however, artificial tears and acupuncture combined group showed difference only between before and after the treatment, which is not statistically significant. 3. The average duration of treatment was statistically 16.3 days for Restasis and acupuncture combined group. Conclusions : Combination of acupuncture and Restasis for dry eye syndrome can shorten the duration of treatment. Therefore, clinical benefit is expected to be worth.

• 한방안이비인후피부과학회지
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• 제33권2호
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• pp.12-22
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• 2020

Objectives : The aim of this study is to review the trend of clinical trials conducted with the intradermal acupuncture treatment on dry eye syndrome. Methods : Through 4 foreign online databases(PubMed, Cochrane Library, EMBASE, and CNKI) and 3 domestic online databases(NDSL, RISS, and OASIS), we searched for clinical studies performed acupuncture treatment for dry eye syndrome from 2000 to 2020. Only randomized controlled trials(RCT) were selected and analyzed with the research method. Results : A total of 4 studies were reviewed. Cuanzu(攢竹, BL2), Taiyang(太陽, EX-HN5), and Sibai(四白, ST2) were the most frequently used acupoints in the studies. Among the evaluation indexes, Schirmer I test(SIT), tear film break-up time(BUT) were the most frequently used outcomes. In the most of the 4 studies, intradermal acupuncture treatment showed significant therapeutic effects for dry eye syndrome. Conclusions : These results suggest that it is necessary to develop more detailed standards for intradermal acupuncture treatment method as the method of intradermal acupuncture is getting more diverse, and objective tools are needed to evaluating dry eye syndrome.

• 대한한의학회지
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• 제24권2호
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• pp.109-120
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• 2003

Objectives: This study was conducted to evaluate the clinical efficacy of EC102, a composition containing oriental medicine, for relieving VDT syndrome, including eye symptoms and musculo-skeletal symptoms. Methods: The study was conducted by using a double blind randomized controlled trial design. 40 subjects were randomly assigned to the placebo group or the EC102 group. The visual analogous scale (VAS) was used to evaluate various VDT symptoms, including eye pain, eye fatigue, back pain, shoulder pain and so on. Refractory indexes were measured using refractometer, and tear film break-up time (BUT) were measured using fluorescein strip. Blood circulation was measured using photo-plethysmography. Blood pressure and blood biochemistry were also measured. Statistical analysis was conducted by a Mann-Whitney test using SPSS 9.0 software. Results: The EC102 group showed a statistically significant reduction of eye symptoms including eye fatigue, eyelid fatigue, itching, pain, and photophobia when compared with the placebo group (P<0.05). The EC102 group also showed a statistically significant reduction of back pain compared with the placebo group (P<0.05). No side effects on liver function and blood biochemistry were observed. Conclusions: EC102 has significant clinical efficacy for relieving symptoms of VDT syndrome.

• 한국안광학회지
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• 제13권3호
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• pp.19-28
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• 2008

목적: 한국인 소프트 콘택트렌즈 착용자에서 나타나는 증상을 이해하고 증상과 눈물검사값과의 상관성을 조사하고자 하였다. 방법: 안과적 질환이 없고 소프트 콘택트렌즈 착용기간이 18.60${\pm}$16.92개월인 착용자 62명(남: 20명, 여: 42명, 평균연령은 23.95${\pm}$4.38세)을 대상으로 설문지 검사 및 3 종류의 눈물검사를 시행하고, 자각적 증상과 타각적 증상을 조사하여 상관성을 분석하였다. 결과: 소프트 콘택트렌즈 착용 중 나타난 자각적 증상의 빈도와 정도는 건조감, 충혈, 피곤함의 순으로 나타났다. 증상의 빈도는 건조감은 모래가 들어간 느낌과, 충혈은 열감과, 피곤함은 이물감과 상관성이 높았고, 증상의 정도는 눈부심은 시력변동과, 이물감은 모래가 들어간 느낌의 상관성이 높았으며 이러한 증상은 McMonnies' 설문검사값과 상관성이 있었다. 타각적 증상으로 결막충혈과 윤부충혈은 병적인 수준은 아니지만 주된 증상으로 나타났고 각결막염색은 발생빈도는 낮지만 눈물막파괴시간이 짧을수록 통계적으로 유의하게 발생빈도가 증가하였다. 결론: 한국인 소프트 콘택트렌즈 착용자의 경우 건조감, 충혈 및 피곤함을 많이 느끼고 이러한 증상은 서로 상관성을 갖고 있으며 콘택트렌즈 착용기간과 상관성이 있으나 자각적 증상과 타각적 증상의 발생은 상관성이 없는 것으로 사료된다.

• Elastomers and Composites
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• 제46권4호
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• pp.335-342
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• 2011

비산회를 첨가한 폐 PE의 직접적인 재활용 및 용도 개발을 위하여 재생 폴리에틸렌 수지와 순수 HDPE를 기본으로 비산회(fly ash)와 블렌드하여 비산회/재생 PE 복합재료를 치합형 동방향 회전 이축 압출기(fully intermeshing co-rotating twin screw extruder)를 이용하여 각 조성별로 제조하였다. 본 연구에서는 플라스틱 수지(재생 PE, HDPE)와 비산회의 혼합비를 (0~40) wt.%로 하였고 비산회의 함량 변화에 따른 물성을 비교하였다. 세 종류의 PE 모두 비산회 함량이 증가할수록 항복인장강도가 감소하고, 파단신율이 감소한다. 내마모성 시험 결과는 사포 거칠기가 증가할수록 내마모성이 떨어지고 거칠기가 감소할수록 충전제의 함량에 따라 내마모성이 증가한다. Notched Constant Ligament Stress 시험에서는 신재 PE와 재생 PE의 경우 하중의 변화에 따라 파괴 시간이 짧아지는 결과를 나타냈고, 비산회가 혼합된 KRPE 복합체는 신재 PE, 폐 PE 그리고 신재 PE 복합체 및 JRPE 복합체와 비교할 때 상대적인 파괴 시간은 짧게 나타나지만 매설용 구조물에 대한 한국산업표준에서 정하는 20% 노치 깊이, 15%의 하중에서 24시간 이상의 저속 균열저항성을 나타내어 지하매설용 구조체로서 하수 이음관/받침대와 옥외구조물로서 가로수 보호의자와 같은 구조물에 적용할 수 있을 것으로 판단한다.

• 한방안이비인후피부과학회지
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• 제32권1호
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• pp.42-58
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• 2019

Objectives : The aim of this study is to review the methodology of clinical trials conducted with the acupuncture and moxibustion treatment on Dry eye syndrome. Methods : Through four foreign online databases(PubMed, Cochrane library, EMBASE, CNKI) and two domestic online databases(NDSL, OASIS), we searched for clinical studies that performed moxibustion for dry eye syndrome from 2000 to December 2018. Only randomized controlled trials(RCT) were selected and anlyzed according to the research method. Results : A total 12 studies were reviewed and conducted in China. BL1, ST2, BL2 were most frequently used acupoints in moxibustion treatment. Among the evaluation indexes, Schirmer I Test(SIT), Tear break-up time(BUT) were used most. In most of the 12 studies, moxibustion treatment showed significant therapeutic effects. Conclusions : These results suggest that it is necessary to develop more detailed standards about moxibustion treatment method as the method of moxibustion is getting more diverse, and objective tools are needed in evaluating dry eye syndrome.

• 대순사상논총
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• 제24_2집
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• pp.85-115
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• 2015

The Reordering of the Universe(天地公事) pursuing the Latter world(後天)'s ideal world while denying the Former world(先天) is composed of enormous rituals. The Dosu(度數) is formed through these rituals and the world is transformed according to the Dosu. The people who follow the Sangje(上帝), the subject of this universe reordering and also participate in the Reordering of the Universe are called as the followers. The follower group can be said as a ritual group in the aspect that they participate in the ritual for the Reordering of the Universe. They not only observed the rituals but also actively participated in them, so took certain roles in forming the Dosu. That is, they performed certain, given roles in developing the rituals, or actively proposed their ideas under the Sangje's leadership, and participated in the process realizing the Dosu. Therefore it can be said that they were a group initiatively participating in the process overcoming the Former world's Sangguk(相克) world, and making the latter world's ideal world. It seemed that the followers at that time might have gone through a certain entrance ritual process in order to join in such a follower group. The 『Jeon-Gyeong』 recorded the entrance rituals of a man called as Cha Gyeong Seok among tremendous followers relatively in detail. According to the 『Jeon-Gyeong』, he first had to get a unique test in the entrance process, and the test was proceeded in several stages: the wisdom test reflecting the Sangje's unusual intelligence, the patience test to endure physical, psychological pains for the great ethic, and the test to evaluate the testee's ability to give up past oneself and to follow the Sangje with a new body & mind. In the process separating himself from the past his appearance, Gyeong-Seok, the candidate to enter, faced a liminal situation, and then performed the incorporation rite. In this process, the purification rite going him out of the past relationship of benefits & grudges was performed, and he was given the regulations to comply as a member of the follower group. Through such serial processes, his entrance in the follower group was allowed. What requested to the candidate in this entrance process was the severance from one's past. For that, the candidate was needed to go out of his past life habits, to free from the relationship of benefits and grudges, and to sever him from his past faults. Such severance was the precondition for him to go out of the Former world's negative reality and to break from the Sanggeuk habits. Another thing requesting to the candidate as well as the severance from his past was to establish a new ideal. The new ideal should be matched with the ideal of the Reordering of the Universe whose main ideology was the Haewon-Sangsaeng(解冤相生). Such ideal can be said as the driving force to proceed toward the new ideal world of Latter World. And the candidate was requested to purify his mind and to participate in the Universe Fair Judgement (天地公庭). That can be said as an important condition for the new member directly to participate in the ritual of the Reordering of the Universe dramatically transforming the world. Finally, the candidate was given the regulations for his ascetic practice(修道) as well as his participation in the Reordering, and was requested to comply them. After becoming a member of this follower group, one had to practice his asceticism through the compliance with such regulations and the training of mantras(呪文) in order to accomplish the goal called as Dotong(道通). By fulfilling these requirements, the newly entered member could have the qualification to perform a certain role in the ritual of the Reordering of the Universe, and could accomplish his religious ideal.