• The Korean Journal of Physiology
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• v.29 no.2
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• pp.279-289
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• 1995

This study was designed 1) to develop a hypertensive animal model in which the blood pressures (BPs) of symmetric regions (right and left upper extremities) are significantly different and 2) to test the effect of BP per se on the contractility and endothelium-dependent relaxation of vascular smooth muscle. Rabbits were anesthetized with sodium pentobarbital and ventilated with room air via animal respirator. The transverse aorta was exposed through the left second intercostal space and the lumen of the aorta was narrowed partially by ligation using 3-0 silk and a probe at a point between the origins of the brachiocephalic trunk and the left subclavian artery. Four to eight weeks postoperatively, BPs were measured in the carotid artery as the high BP area (proximal to coactation site) and in the femoral artery as the low BP area (distal to coarctation site). In the animal model, pressure-overload hypertension was developed and the BP of the right subclavian artery was higher than that of the left subclavian artery. The concentrations of circulating epinephrine, norepinephrine, angiotensin I, and angiotensin II were measured. The right and left subclavian arteries and their branches were used for isometric tension recording in organ baths and their responsiveness to phenylephrine, serotonin, acetylcholine, and sodium nitroprusside were examined. The BPs of carotid and femoral artery in control animals were $116{\pm} 12/75{\pm}9\;mmHg (mean ${\pm}SEM$) and $130{\pm}16/68{\pm}9\;mmHg$ respectively, while those of carotid and femoral artery in the hypetensive animals were $172{\pm}6/111{\pm}10\;mmHg$ and 136{\pm} 4/100 {\pm}9\;mmHg$ respectively. There were no significant differences in the concentrations of circulating epinephrine, norepinephrine, angiotensin I, and angiotensin II between controls and the animal models. No significant differences were found in the vascular sensitivities to phenylephrine and serotonin between the high pressure-exposed vessels and the low pressure-exposed vessels. However, the endothelium-dependent relaxation to acetylcholine and nitroprusside-induced relaxation showed significant differences between the high pressure-exposed and the low pressure-exposed subclavian arteries. From the above results, we suggest that the contractility of vascular smooth muscle is unchanged by the elevated pressure per se. However, the endothelium-dependent relaxation to acetylcholine and the nitroprusside-induced relaxation are attenuated by pressure.

• The Journal of Korean Academy of Sensory Integration
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• v.6 no.1
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• pp.35-46
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• 2008

Objective : This study verifies the effects of sensory integrative (SI) therapy on vestibular- and proprioceptive sensory (BPS) processing ability of a child with Asperger Syndrome (AS). Method : A boy who is 11 years and 2 months old took the Functional Independence Measure for Children (Wee-FIM), Canadian Occupational Performance Measure (COPM), Short Sensory Profile, Bruininks-Oserestky Test of Motor Proficiency-2 (BOT-2), and Test of Playfulness (ToP) for the baseline. The child participated in 3 evaluation sessions and 8 therapy sessions based on the AB research design. Duration of each session is 50 min and the therapy session is divided into 40 minutes for treatment and 10 minutes for evaluation. Since the vestibular sense and proprioception build up one's ability of postural control, several tests were employed to evaluate the child' postural control as outcome measure; distance from front leg of chair to heel of the child with sitting (C-H distance), angle between trunk and thigh (hip joint angle) with sitting, and the 'prone-extension posture' which is a subtest of Clinical Observation of Motor and Postural Skill (COMPS) to examine postural control embodied with integration of reflex and BPS processing. Result : During the therapy, average data of the C-H distance is decreased from 27.33cm to 11.69cm, average data of the hip joint angle is also decreased from $43.3^{\circ}$ to $20^{\circ}$, and average time for the prone-extension posture is increased from 13.15seconds to 24.84seconds. Conclusion : This result indicates that the ability to postural control in sitting and to maintain the prone-extension posture can be improved by sensory integrative therapy, with enhanced BPS processing.

• Journal of Bio-Environment Control
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• v.17 no.2
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• pp.132-137
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• 2008

This experiment was conducted to investigate the effect of supplemental lighting of low light intensities on growth and yield of rose 'Vital' in a forcing culture. Metal halide lamp (MH), High pressure sodium lamp (HSP), and MH+HSP were used as the light sources, and they were set up at a $310\;cm{\times}450\;cm$ interval and at 120cm above the culture beds. Light intensity at 1m point distance from supplemental lighting sources was $32{\sim}34\;{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$. Days to the 1st and 2nd harvests decreased by $5{\sim}8$ and $3{\sim}5$days, respectively in supplemental lighting treatment as compared to the control. Days to harvesting was the shortest in MH+HPS treatment, followed by BPS and MH, although there was no significant difference between HPS and MH treatments. The growth was better and incidence of blind shooting decreased by $5{\sim}7%$ in supplemental lighting treatments than the control, increasing marketable cut flowers. The incidence of blind shoot was the lowest in MH+BPS treatment, and there were no significant difference between MH and BPS treatments. In conclusion, supplemental lighting of low light intensities was effective in reducing days to flowering and reduced occurrence of blind shoots.

• Applied Biological Chemistry
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• v.49 no.2
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• pp.135-139
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• 2006

This study was carried out to investigate the cosmeceutical activities of Persicae semen. Cosmeceutical activities include anti-oxidant, tyrosinase inhibition effects and nitrite scavenging ability. The Persicae semen was divided into three parts, Bean of Persicae semen (BPS), Shell of Persicae semen (SPS) and Nibs of Persicae semen (NPS). In the electron donating ability test, 1,000ppm of water extract from BPS showed an effect of 89%, while 1,000 ppm of ethanol extract from SPS showed an effect of 87%. These results are higher compared to those of BHA at the equal concentration. We were able to get an effect of 98% from all of Persicae semen ethanol extract of 10,000 ppm in the tyrosinase inhibition test. Nitrite scavenging ability test, ethanol extract from BPS was decreasing to 96% by addition of 1,000ppm. According to these results, we find that Persicae semen applicable to advanced material for cosmetics. From the above results, it was confirmed that Persicae semen could be used in functional cosmetics.

• Journal of Microbiology and Biotechnology
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• v.29 no.7
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• pp.1043-1052
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• 2019

Active lipase-producing bacterium Burkholderia gladioli Bps-1 was rapidly isolated using a modified trypan blue and tetracycline, ampicillin plate. The electro-phoretically pure enzyme was obtained by purification using ethanol precipitation, ion-exchange chromatography, and gel filtration chromatography. The molecular weight was 34.6 kDa and the specific activity was determined to be 443.9 U/mg. The purified lipase showed the highest activity after hydrolysis with $p-NPC_{16}$ at a pH of 8.5 and $50^{\circ}C$, and the $K_m$, $k_{cat}$, and $k_{cat}/K_m$ values were 1.05 mM, $292.95s^{-1}$ and $279s^{-1}mM^{-1}$, respectively. The lipase was highly stable at $7.5{\leq}pH{\leq}10.0$. $K^+$ and $Na^+$ exerted activation effects on the lipase which had favorable tolerance to short-chain alcohols with its residual enzyme activity being 110% after being maintained in 30% ethanol for 1 h. The results demonstrated that the lipase produced by the strain B. gladioli Bps-1 has high enzyme activity and is an alkaline lipase. The lipase has promising chemical properties for a range of applications in the food-processing and detergent industries, and has particularly high potential for use in the manufacture of biodiesel.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.49 no.2
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• pp.75-85
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• 2023

Objectives: Suspending bisphosphonates (BPs) to reduce the risk and severity of medication-related osteonecrosis of the jaw (MRONJ) remains controversial. In this study, we quantitatively evaluated the clinical significance of BP suspension before surgery in osteoporosis patients with MRONJ. Materials and Methods: We analyzed 24 osteoporosis patients with MRONJ who were treated from 2012 to 2020 at Seoul National University Dental Hospital and compared the treatment outcomes of those who suspended BPs with those who did not. The number of surgical interventions, follow-up panoramic radiographs for relative bone density measurement, and laboratory blood tests including white blood cells, erythrocyte sedimentation rate, absolute neutrophil count, hemoglobin, hematocrit, and alkaline phosphatase were analyzed. ANOVA, Student's t-test, and Mann-Whitney U tests were used to compare results. Fisher's exact test was used to discover the association between treatment outcome and BP suspension, and Pearson's correlation test was used to measure the statistical relationship between the changes in serum inflammatory markers. Results: The number of interventions was significantly higher in the non-drug suspension group due to recurrence (P<0.05). The relative bone density in patients who suspended BPs was significantly different over time (P<0.05), with the highest density at one-year follow-up. Fisher's exact test shows an association between successful treatment outcomes and BP suspension. The alkaline phosphatase and erythrocyte sedimentation rate levels decreased significantly in the BP-suspended group, and a positive correlation was found between these elevated markers. Conclusion: A significant increase in bone density throughout follow-up and a lower number of interventions were found in the BP suspension group compared to the non-drug suspension group. Also, BP suspension decreased inflammatory markers in the serum after surgery, resulting in good treatment outcomes. BP suspension is a prognostic factor for MRONJ and should be implemented before surgery.

• Electronics and Telecommunications Trends
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• v.10 no.4 s.38
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• pp.37-55
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• 1995

고속 표준 프로토콜인 FC를 기반으로 한 Gigabit LAN 기술은 다양한 응용과 함께 Giga bps급의 높은 대역폭과 적은 전달지연을 갖는 고속 통신망으로서 매우 적합하다. 본 논문에서는 Gigabit 통신에 적합한 고속 표준 프로토콜인 FC의 표준화 내용과 프로토콜을 살펴보고, FC 기반의 LAN 기술을 위한 호스트 접속 기술 및 현재 연구/개발중인 Gigabit LAN을 구성하기 위한 요소시스템인 GIGAways 스위치 그리고 internetworking을 위한 FC-ATM Transport에 대하여 기술하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10b
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• pp.163-165
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• 2003

ebXML은 단일한 방법으로 기업간 비즈니스 프로세스의 자동화를 지원할 수 있는 표준이다. 본 논문은 ebXML의 CPA(Collaboration Protocol Agreement) 및 BPS(Business Process Specification)에 정의된 내용에 따라 프로세스 자동화를 관리하는 BSI(Business Process Interface) 엔진의 주요 설계 내용을 기술한다. 고려 사항으로는 BPSS 1.05, CPA 2.0을 지원하였다.

• Proceedings of the IEEK Conference
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• 2001.06a
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• pp.65-68
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• 2001

The selection transmit diversity is an effective way to avoid the deep fading in a wireless channel. However, it may not completely eliminate the SNR fluctuation of a received signal at the receiver. This letter presents an application of an adaptive modulation effectively exploiting the SNR variation over time for a higher spectral efficiency to the conventional selection transmit diversity. Numerical results show that the proposed scheme can achieve a SNR gain of about 7 dB over the conventional selection diversity in a flat Rayleigh fading environment, when a BER of 10$^{-3}$ and a spectral efficiency of 2 bps/Hz are required..

• Proceedings of the IEEK Conference
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• 2000.06e
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• pp.89-92
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• 2000

A wire communication module for PLC controller was developed. This system consists of RF module interface part, RS232 serial communication control part, LED display part and control S/W with GUI interface. RF communication frequency is controlled by PLL controlling and communication rate is also controlled as 1200 and 4800 bps. Communication and control status are displayed on LED. As a S/W part, graphic user interface on Window 95 O.S. was developed. To show the validity of the developed system, severial communication and control of PLC system were experemented.