• The Journal of the Korean dental association
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• v.13 no.11
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• pp.1021-1024
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• 1975

Bo-sung dental gold alloy was tested an physical properties, tarnish and corrosion restistance. The results were as follows : 1. No differences beween physical properties of Bo-Sung dental gold alloy and American Dental Association Specification No. 5. 2. Tarnish and Corrosion resistance of Bo-Sung dental gold alloy were favorable of dental uses. 3. Bo-Sung dental gold alloys showed equiaxed grain structure in microstructures.

• The Journal of Korean Medical History
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• v.13 no.2
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• pp.93-107
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• 2000

To generalize how early-Chosun medical achievements represented by "Hyang Yak Jib Sung Bang" and "Eui Bang Yoo Chui" influenced the publishment of "Dong Eui Bo Gam", and what academic achievements of "Dong Eui Bo Gam" are, I have compared the compositions of "Dong Eui Bo Gam" to two representative medical literature of early-Chosun era and examined the changes in organizations, and I was able to find deep connections among "Dong Eui Bo Gam", "Hyang Yak Jib Sung Bang" and "Eui Bang Yoo Chui".

• The Journal of Korean Medical History
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• v.13 no.2
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• pp.131-139
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• 2000

Through studies on "Dong Eui Bo Gam", I have found out that 'Yang Saing' theroy in "Dong Eui Bo Gam" is based on 'Cha Eum Ron' and "I Ching" has much influenced on "Dong Eui Bo Gam".

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.1
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• pp.295-301
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• 2017

Botulinum neurotoxin (BoNT/A) is a neurotoxin that selectively attacks the peripheral cholinergic nerve endings. It is produced by Gram -positive, endospore-forming strict anaerobic bacteria, Clostridium botulinum. Since BoNT/A could be a biothreat agent, as well as a contaminator of food and water supplies, the development of sensitive assays for toxin detection and potent antitoxin for the treatment of intoxication is necessary. In this study, for the purpose of producing monoclonal antibodies (mAbs) that are capable of neutralizing Botulinum neurotoxin type A (BoNT/A), scFv (single-chain variable domain fragment) libraries from the rabbit antisera against BoNT/A was fused to a human IgG. The resulting recombinant scFvIgG antibody protein was expressed in stable cell lines and was purified using a protein A affinity chromatography. The efficacy of scFvIgG mAb was confirmed by ELISA and was evaluated for the neutralization of BoNT/A in vivo. Such an in vivo toxin neutralization assay was performed using mice. Although scFvIgG antibody proteins (10 ug) failed to fully protect the mice challenged with BoNT/A (100,000 $LD_{50}$), it significantly prolonged the survival time. These results suggest that scFvIgG mAb may be capable of neutralizing BoNT/A single-chain variable domain fragment.

• Journal of Electrical Engineering and Technology
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• v.9 no.6
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• pp.2025-2035
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• 2014

The read range of UHF mobile readers can be extended by a booster for mobile RFID readers (BoMR). But in an environment where multiple BoMRs are installed, the read success rate may be decreased due to signal interference. This paper proposes three arbitration methods based on interference estimation with the purpose of enhancing the read success rate. A central arbitration server manages global information in centralized arbitration method (CAM) without broadcast/multicast communication facility. In fully distributed arbitration method (FDAM), all the arbitration messages are broadcasted from a BoMR to every BoMR, and each BoMR decides with broadcasted global information. Events in FDAM are serialized naturally with broadcasted messages. Cluster Distributed Arbitration Method (CDAM) forms clusters with multicasted BoMRs and a selected BoMR acts as an arbiter in the cluster. Such effects as lengthened read range, improved the read success rates of readers can be obtained by the proposed methods without any hardware modification. In order to evaluate the arbitration methods, the RFID system is modeled by using the DEVS formalism and simulated by using the DEVSim++.

• The Journal of Korean Medical History
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• v.19 no.2
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• pp.119-143
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• 2006

Man-Byeong-Hoi-Chun(萬病回春) is a representative writing of Gong Zhongxian. It was generally used by Koreans in Joseon(朝鮮) era and issued many times in the latter period of Joseon dynasty. We investigated the Jeung-Bo-Man-Byeong-Hoi-Chun (增補萬病回春, An enlarged edition of the Man-Byeong-Hoi-Chun), which is published in the 17th century, coming to a conclusion like the followings. 1. In Joseon(朝鮮), there was the J eung-Bo-Man-Byeong-Hoi-Chun which was made through revision and enlargement of the Man-Byeong-Hoi-Chun written by Gong Zhongxian of China. 2. There are two versions of the Jeung-Bo-Man-Byeong-Hoi-Chun pressed in Joseon, which are written by Kim Yuk(金堉) in 1656 and by Kim Seok-ju(金錫胄) in 1679. 3. The representative medical books of Joseon such as Eui-Rim-Chual-Yo-Sok-J ip (醫林撮要續集), Dong-Eui-Bo-Gam (東醫寶鑑), J e-Jung-Sin-Pyeon(濟衆新編) contained quotations from the J eung-Bo-Man-Byeong-Hoi-Chun(增補萬病回春), not from the Man-Byeong-Hoi-Chun (萬病回春). 4. The Jeung-Bo-Man-Byeong-Hoi-Chun(增補萬病回春) contained not only the essence of the Chinese medicine but also new medical systems reflecting actual circumstances of Joseon at that time. So, it can be recognized as the foundation of the Joseon medicine in the latter period of the dynasty.

• The Journal of Korean Medical History
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• v.15 no.1
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• pp.147-182
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• 2002

By studing the congestion theory of Choo Dan-kyei mentioned in "DongEuiBoGam", I have reached following conclusions. 1. Dan-kyei's congestion theory influenced greatly on "DongEuiBoGam". The congestion theory of "DongEuiBoGam" is built up with several theories centering round on Dan-kyei's theory and Huh-Jun's own opinion in addition. 2. Dan-kyei's congestion theory has given theoretical foundation to the classification and diagnosis of congestion reported in "DongEuiBoGam"-Congestion Chapter. 3. Dan-kyei's congestion theory offers many examples of symptoms reported in "DongEuiBoGam"-Congestion Chapter. It's shown well through outer symptoms, several congestion disease, congestion mass, and "congestion never sudden death", etc. 4. Dan-kyei's congestion theory has influenced greatly on treatment of congestion reported in "DongEuiBoGam"-Congestion Chapter, and it's well shown through spewing method, grand method in congestion treatment and common medicine of congestion, etc. 5. Dan-kyei's congestion theory offers variety of treating methods to symptoms caused by congestion reported in "DongEuiBoGam". It's shown variously through upper stomachache, stomachache, back pain, side pain, "San", joint pain, Summer disease, internal injury, cough and morning sickness, etc.. 6. Dan-kyei's congestion theory has factors that could be operated to common diseases of mordern people. They can be classified as food congestion, alcohol congestion, obstruction congestion and Qi congestion, and they are clinically very efficient.

• Journal of the Korean Home Economics Association
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• v.34 no.2
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• pp.129-142
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• 1996

This paper pursues a comparative study on the design and function of the ready-made Bo-Son and the Bo-Son Pattern based on teaching and learning materials. It intends to investigate whether the Bo-Son is designed to suit to Kinetics of foot or to give the ease of wearing and taking off. The following results came out through trial wearing. 1) The Bo-Son pattern suggested in teaching materials can not satisfy the wearers with partial modification due to design problem. On the other hand, the ready-made Bo-Son can satisfy them with partial modification. 2) The important factor in designing the pattern of Bo-Son is the posture of foot when putting on it, that is, the height of the heel of the foot from the floor, the length of the heel, the length of toe and the bending angle of toe. 3) As a result of this study, in the design of the improved Bo-Son pattern, it is most suitable when the size of foot is 230mm, the height of the heel of the foot is 12.5cm, and and angle of the front toe of a sock is 35$^{\circ}C$.

• The Journal of Korean Medicine
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• v.22 no.3
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• pp.51-62
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• 2001

Objectives : In Oriental Medicine, the improvement of constipation is very important for patients at the acute stage of cerebrovascular accident. For constipation, oral medicine has usually been used but is not available to stroke patients with dysphagia and mental disorder, and may bring about side effects on the gastrointestinal tract. In such cases, general enema has been used for assistant therapy, We needed to develop a more effective enema technique on constipation of stroke patients. Methods : Sixty-three patients were researched. We treated 29 patients with Bo-Ryu enema and 34 patients with general enema. To compare the effect of the Bo-Ryu enema group with that of the general enema group, we analyzed general characteristics, bowel movement, abdominal examination and related symptoms. Results : Sixty-three patients comprised the Bo-Ryu (n=29) and general (n=34) enema groups. Between the Bo-Ryu and general enema groups, the Bo-Ryu enema was more effective than the general enema in the number of bowel movements, total and corrected amount of stool, tonus of rectus abdominis muscle and abdominal discomfort. However, there were not significant differences in the power of abdominal muscle, digestion and physical power. Among the subgroups, Bo-Ryu enema group was most effective in the number of bowel movements, total amount of stool and tonus of rectus abdominis muscle, and Bo-Ryu enema group was best in the corrected amount of stool and abdominal discomfort. Conclusions : Bo-Ryu enema should be considered as an effective and safe treatment for patients with constipation during the acute stage of cerebrovascular accident.

• The Korean Journal of Physiology and Pharmacology
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• v.19 no.4
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• pp.349-355
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• 2015

We examined the effects of peripherally or centrally administered botulinum neurotoxin type A (BoNT-A) on orofacial inflammatory pain to evaluate the antinociceptive effect of BoNT-A and its underlying mechanisms. The experiments were carried out on male Sprague-Dawley rats. Subcutaneous (3 U/kg) or intracisternal (0.3 or 1 U/kg) administration of BoNT-A significantly inhibited the formalin-induced nociceptive response in the second phase. Both subcutaneous (1 or 3 U/kg) and intracisternal (0.3 or 1 U/kg) injection of BoNT-A increased the latency of head withdrawal response in the complete Freund's adjuvant (CFA)-treated rats. Intracisternal administration of N-methyl-D-aspartate (NMDA) evoked nociceptive behavior via the activation of trigeminal neurons, which was attenuated by the subcutaneous or intracisternal injection of BoNT-A. Intracisternal injection of NMDA up-regulated c-Fos expression in the trigeminal neurons of the medullary dorsal horn. Subcutaneous (3 U/kg) or intracisternal (1 U/kg) administration of BoNT-A significantly reduced the number of c-Fos immunoreactive neurons in the NMDA-treated rats. These results suggest that the central antinociceptive effects the peripherally or centrally administered BoNT-A are mediated by transcytosed BoNT-A or direct inhibition of trigeminal neurons. Our data suggest that central targets of BoNT-A might provide a new therapeutic tool for the treatment of orofacial chronic pain conditions.