• Journal of Naturopathy
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• v.10 no.1
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• pp.26-32
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• 2021

Purpose: At acupoint pressure, the pressing direction of all acupoints is usually vertical. However, it is not clear whether the vertical direction is toward the belly button or the body's center in the BL52. In this study, the effective direction of acupressure was studied by measuring the pressure pain threshold according to the direction of acupressure in 30 subjects. Methods: The distance from the subject's GV4 to the left and right BL52 and the distance from GV4 to the navel were measured, and then using the ellipse where the left and right BL52 of GV4 pass through the navel, the angles of the navel direction and the body's center were calculated in the left and right BL52. The pressure at the time when the subjects felt pain while pressing the BL52 in two directions was used as the acupressure pain threshold. The pain threshold was measured 3 times at 3 minute intervals on the left and right BL52s of the subject. Results: The acupressure pain threshold measured in the left and right BL52 of the subjects was significantly decreased when pressed toward the trunk center (p < .05). In BL52, it was more sensitive to pressure when the direction of pressure is toward the body's center. Conclusions: Acupressure therapy of acupoint is more sensitive to external stimuli than the surrounding. In this study, acupressure directed toward the trunk center is more efficient than toward the belly button in BL52.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.1
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• pp.50-56
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• 2009

The present study was designed to investigate the effects of Phamacopuncture therapy using Cervi Pantotrichum Cornu (PC) at BL23 BL52 on the regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats, then the related mechanisms were also investigated. In addition, the present author also investigated the effects of phamacopuncture therapy at BL23.BL52 on the rCBF in cerebral ischemic rats. The results in normal rats were as follows; PC (3 mg/kg and 5 mg/kg) at BL23 BL52 significantly increased rCBF but decreased MABP. This result suggests that PC at BL23 BL52 significantly increased rCBF by dilating pial arterial diameter. Increase of PC (5 mg/kg)-induced rCBF was significantly inhibited by pretreatment with indomethacin (1 mg/kg, i.p.), an inhibitor of cyclooxygenase and methylene blue ($10{\mu}g/kg$, i.p.), an inhibitor of guanylate cyclase. Decrease of PC (5 mg/kg)-induced MABP was significantly increased by pretreatment with methylene blue but was decreased by pretreatment with indomethacin. These results suggested that the action of PC (5 mg/kg) was mediated by guanylate cyclase. The results in cerebral ischemic rats were as follows ; The rCBF was significantly and stably increased by PC (5 mg/kg) during the period of cerebral reperfusion, which contrasted with the findings of rapid and marked increase in Control group. In conclusion, these results suggest that phamacopuncture therapy using Carthami flos at BL23 BL52 can increase rCBF in normal state, and improve stability of rCBF in ischemic state. In addition, the present author also suggest that related mechanisms are involved in guanylate cyclase pathway.

• Journal of Acupuncture Research
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• v.33 no.2
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• pp.89-96
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• 2016

Objectives : The aim of this study is to investigate the needling depth of Hwangmun (BL51) and Jisil (BL52) retrospectively using an L-spine MRI. Methods : We measured the shortest distance from the skin to transversalis fascia at both sides of Hwangmun and Jisil, and analyzed the difference between male and female using a student t-test, and between the left and right sides with a paired t-test. Results : In the case of males, the average depth of left Hwangmun was $48.24{\pm}10.16mm$, and that of right was $47.23{\pm}9.59mm$ ; left Jisil was $56.91{\pm}9.00mm$ and right was $55.74{\pm}8.75mm$. In the case of females, the average depth of left Hwangmun was $42.26{\pm}9.29mm$, and that of right was $41.63{\pm}9.32mm$ ; left Jisil was $49.21{\pm}10.77mm$ and right was $48.41{\pm}11.38mm$. The depth of male insertion was deeper than that of female in Jisil, but there was no significant difference according to gender in Hwangmun. Conclusion : For males, the needling depth of left Hwangmun is 37.21 ~ 68.23 mm and right is 36.91 ~ 70.50 mm, while left Jisil is 42.97 ~ 70.84 mm and right is 43.75 ~ 72.00 mm. For females, the needling depth of left Hwangmun is 26.80 ~ 68.28 mm and right is 25.70 ~ 65.59 mm, while left Jisil is 30.94 ~ 79.06 mm and right is 28.13 ~ 77.27 mm.

• Journal of Pharmacopuncture
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• v.2 no.1 s.2
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• pp.63-71
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• 1999

Counts of RBC and proportion of packed cell volume(PCV) showdc no difference among treatment groups. the values of hemoglobin in rat showed a tendeuy to increase in herbal-acupuncture group, however the values of hemoglobin in guineapig and rabbit showed no significant difference in the treatnent groups. the count of WBC showed high in the chishiI(BL52) herbal-acupuncture group. The proprtion of neutrophils showed no significant difference in rabbit, however the values in guinea-pig and rat showed a tendency to increased in herbal-acupuncture groups. The proportion of lymphocytes in rabbit and guinea-pig showed a tendency to decreast in herbal-acupuncture groups, however the values in rat showed no significant difference. The proportion of Eosinophils and monocytes showed no significant difference in all the treated groups. Results from this study indicated that shinsu(BL23) and chishil(BL52) herbal-acupuncture with palmijihwangtang elivate the biglogical function in Rabbit Guinea-pig and Rat.

• Journal of Acupuncture Research
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• v.23 no.3
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• pp.1-19
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• 2006

Objectives : This study was carried out to determine the effects of Gamidokwalgisaeng-tang(GDS) oral administration and electro-acupuncture at $BL_{52}$ & $GB_{39}$ on the postmenopausal osteoporosis. Methods: In order to study the effects of the Gamidokwalgisaeng-tang(GDS) oral administration and electro-acupuncture at $BL_{52}$, $GB_{39}$ on osteoporotic rats induced by ovariectomy, body weight, femur weight, uterine weight, serum level of osteocalcin, alkaline phosphatase(ALP), cholesterol, triglyceride, estradiol, androstenedione, testosterone and urinary excretions of calcium & phosphorus were measured. Results : 1. Body weight in all experimental group decreased significantly in comparison with ovariectomized group(OVX). 2. The weight of femur compared with body increased significantly in GDS oral administration and combination treatment group in comparison with ovariectomized group(OVX). 3. Uterine endometrial morphology is caused by ovariectomy and the weight of uterus decreased significantly in control and all experimental group in comparison with sham. 4. The serum level of osteocalcin decreased in all experimental group in comparison with OVX, but significantly in electro-acupuncture and combination treatment group. 5. The serum alkaline phosphatase(ALP) activity decreased in electro-acupuncture and combination treatment group in comparison with OVX, but only significantly in electro-acupuncture group. 6. The serum level of cholesterol increased significantly in OVX in comparison with sham and decreased in all experimental group in comparison with OVX, not insignificantly. The serum level of triglyceride increased in all experimental group in comparison with OVX, not insignificantly. 7. Urinary excretions of calcium and phosphorus decreased significantly in all experimental group in comparison with OVX. Conclusion : We suggest that GDS oral administration and electro-acupuncture at $BL_{52}$ & $GB_{39}$ are available for prevention and curing about the postmenopausal osteoporosis.

• Parasites, Hosts and Diseases
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• v.52 no.3
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• pp.273-280
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• 2014

The changing patterns of goblet cell hyperplasia, intestinal epithelial cell turnover, and intestinal motility were studied in ICR and C57BL/6 mice infected with Gymnophalloides seoi (Digenea: Gymnophallidae). Whereas ICR mice retained G. seoi worms until day 7 post-infection (PI), C57BL/6 mice showed a rapid worm expulsion within day 3 PI. Immunosuppression with Depo-Medrol significantly delayed the worm expulsion in C57BL/6 mice. Goblet cell counts were increased in both strains of mice, peaking at day 1 PI in C57BL/6 mice and slowly increasing until day 7 PI in ICR mice. In C57BL/6 mice infected with G. seoi, newly proliferating intestinal epithelial cells were remarkably increased in the crypt, and the increase was the highest at day 1 PI. However, in ICR mice, newly proliferating intestinal epithelial cells increased slowly from day 1 to day 7 PI. Intestinal motility was increased in G. seoi-infected mice, and its chronological pattern was highly correlated with the worm load in both strains of mice. Meanwhile, immunosuppression of C57BL/6 mice abrogated the goblet cell proliferation, reduced the epithelial cell proliferation, and suppressed the intestinal motility. Goblet cell hyperplasia, increased intestinal epithelial cell turnover, and increased intestinal motility should be important mucosal defense mechanisms in G. seoi-infected C57BL/6 mice.

• Journal of Korean Medical Ki-Gong Academy
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• v.14 no.1
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• pp.52-62
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• 2014

Objective : The aim of this study is to analyze the effectiveness of Korean Medicine treatment on post-hysterectomy syndrome patients by thermographic change during treatment. Methods : 5 female patients who had a hysterectomy within a year were treated with Korean Medicine concluding acupuncture, herbal medicine, cupping therapy, herbal bath. We evaluated the thermographic differences by checking Digital Infrared Thermal Imaging(D.I.T.I.) at CV17(膻中), CV4(關元), ST3(巨髎), BL15(心兪), and BL23(腎兪). Results : In consequence of Korean Medicine Treatment for 3 weeks, thermographic differences between CV17(膻中) and CV4(關元), ST3(巨髎) and CV4(關元), BL15(心兪), and BL23(腎兪) tended to decrease. Conclusion : After Korean Medicine treatment, thermographic differences between upper body and lower body tended to decrease cause shangrexiahanzheng(上熱下寒證) made by hysterectomy became moderated.

• Journal of Korean Medical Ki-Gong Academy
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• v.16 no.1
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• pp.78-100
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• 2016

Objects : The purpose of this study is to value measuring of sagital, horizontal, frontal aspects of DITI as scale of low back pain. Methods : We investigated 16 patients with low back pain who had visited in the H Korean medicine hospital in Gimpo city, Gyeonggi Province from January 1st to, August 31th, 2016. We evaluated the change of them by using Digital Infrared Thermographic Imaging. Results : There is meaningful differences in values for CV12 in pretest and posttest which were observed by DITI. In the Correlation analysis of values of meridian points in pretest and posttest, there is relation ΔSagital04(ST25/BL52), ΔSagital04(CV4/GV3) with low back pain. Conclusions : These results suggest that ΔSagital04(ST25/BL52), ΔSagital04(CV4/GV3) can be used as value of Low back pain.

• Korean Journal of Acupuncture
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• v.20 no.4
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• pp.41-52
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• 2003

Objectives : Circii Herba has been used as a natural drug for the treatment of stress digestive system disease. The aim of this study is to investigate the role of Circii Herba aqua-acupuncture solution (CHAS) in experimental oxidative liver injury. Methods : In order to investigate the effects of CHAS on acute liver injury, male ICR mice were pretreated with CHAS(0.2 ml/mouse/day) at the loci of BL18 and CV12 for 6days, starved for 24hrs, and administerated acetaminophen(500 mg/kg, i.p.). After acetaminophen administeration, mice were sacrificed, and the liver was removed, rinsed with ice-cold $1.15{\%}$ KCI buffer, and homogenized at $4^{\circ}C$. Fractions(fraction Ⅰ, Ⅱ, Ⅲ) were isolated by differential centrifugation. Lipidperoxide, total SH, and glutathione(GSH) levels were measured in the Fraction Ⅰ. In addition, activities of hepatic enzyme, such as catalase, glutathione peroxidase(GSH-Px) were measured in the Fraction Ⅱ, and glutathione S-transferase(GST) was measured in the Fraction Ⅲ. Results : In vivo treatment of CHAS(BL18 and CV12) showed effective inhibition of acetaminophen induced lipid peroxidation, and showed elevations of total SH, GSH level, catalase, GSH-Px, GST activities. Conclusions : These results suggested that CHAS might suppress the formation of oxidative metabolites, and prevent acetaminophen induced hepatotoxicity.

• Journal of Acupuncture Research
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• v.22 no.5
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• pp.79-90
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• 2005

Objectives : The purpose of this study Is to evaluate the effect of acupuncture treatment on the lunbar extensor muscle flexibility of normal people by comparing ICT(interferential current therapy) group. Methods : This study was carried out on 30 subjects employed using 15 qestionaires and radiography. Subjects were divided into two groups including acupuncture treatment group and ICT treatment group. In the control group, subjects were taken ICT treatment for 15 minutes and in the test group were needled at BL23, BL24, BL25, BL4O, BL52 and BL60 for 15 minutes. Then subjects did the sit and reach test and the standing and reach test, right after treatment and after 10minutes. Results : 1. Compared to the before -treatment result of the sit and reach test and standing and reach test, the after-treatment result showed the improved flexibility. 2. The result gained from the test group is slightly larger than that of the control group. Conclusion : We brought to the conclusion that acupuncture treatment has possibility to increase flexibility of lumbar extensor muscle.