• 통합자연과학논문집
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• 제1권1호
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• pp.19-23
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• 2008

Morus alba has been well known for its tonic effect or preventing of hypertension, aging, or diabetes mellitus in Asian countries. To evaluate the its effect on hair growth promotion, we performed the hair regrowth experiment with leaf, branch, root and fruit extract of Morus alba on animal model of C57BL/6 mouse. The hair regrowth effect was remarkable in the mouse treated branch and root extract (with what %), however, little effect on hair regrowth appeared on the mouse treated with leaf extract. Morus alba extract displayed antibacterial effects on Bacillus subtilis, Staphylococcus aureus, Pseudomonas and Candida albicans. These results indicated that branch and root extract of Morus alba could be applicable for hair regrowth or prevention of hair loss in human.

• 대한한의학회지
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• 제39권1호
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• pp.55-62
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• 2018

Objectives: This study aims to investigate on the nomenclature of acupoints for the Healthcare Terminology Standard. Methods: We investigated the name of acupoints in "Standard Acupuncture Nomenclature (Second Edition)" of WHO, "WHO Standard Acupuncture Point Locations in The Western Pacific Region", "Principles of Meridians & Acupoints", "Details of Meridians & Acupoints" and "Acupuncture Medicine". Results: In books, we found that the name of acupoints was used differently in LI19, TE22, HT3, SI8, ST16, SI16, GB16 and BL8 acupoints. Conclusions: 口禾髎(LI19), 耳和髎(TE22), 少海(HT3), 小海(SI8), 膺窗(ST16), 天窗(SI16), 目窗(GB16), 絡卻(BL8) and 淵腋(GB22) in confused acupoints have been established as the terms of acupoints for the Healthcare Terminology Standard.

• 정보처리학회논문지A
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• 제19A권4호
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• pp.181-186
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• 2012

분산 환경의 계측 및 제어 시스템에서 분산된 디바이스들의 복잡한 동기화 구조를 해결하기 위한 기술의 필요성이 요구되며 그러한 분산시스템 환경에서 시간 동기화를 위해 IEEE 표준인 정밀 클럭 동기화 프로토콜(Precision Clock Synchronization Protocol)을 사용함으로써 문제를 해결 할 수 있다. 본 논문에서는 정확한 시간 동기화를 계측하기 위해 지연 요청-응답(Delay Request-Response) 메커니즘을 이용하여 IEEE 1588v2 PTP를 계측하고 제어 할 수 있는 기능을 BlueScope BL6000A에 구현하였다.

• 생태와환경
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• 제43권1호
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• pp.82-90
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• 2010

본 연구는 섬진강 중 상류 수계의 꺽지자원에 대해서 자원평가의 기초로 사용되는 자원생태학적 특성치들을 분석하고자 하였다. 연령사정을 위한 연령형질로서 이석(otolith)을 사용하였으며, 연령사정 결과, 최고연령은 5세로 나타났다. 체장(BL)과 체중(BW)의 관계식은 $BW=0.0195BL6{3.08}$($R^2=0.966$) 이었으며, 윤문이 형성되었을 때의 체장을 역계산하기 위한 체장(BL)과 이석경(R)과의 관계식은 BL=3.882R+1.66($R^2=0.944$)로 나타났다. 비선형회귀방법을 이용한 von Bertalanffy 성장모델의 매개변수는 이론적 최대체장($L_{\infty}$)이 19.68 cm, 이론적 최대체중($L_{\infty}$)이 188.64 g, 성장계수(K)가 0.17, 체장이 0 일 때의 연령이 -1.46세 등으로 각각 추정되었다. 이를 통해 추정된 성장식은 Lt=19.68(1-$e^{-0.17(t+1.46)}$)($R^2=0.997$)로 나타났다. 생존율을 추정하는 6가지 방법 중 평방오차합(Sum of squared error: SSQ) 이 가장 작은 어획물곡선법을 이용하여 생존율을 추정하였으며, 추정된 생존율(S)는 $0.666\;year^{-1}$으로 확인되었다. 순간자연사망계수(M)와 순간전사망계수(Z)는 $0.346\;year^{-1}$과 $0.407\;year^{-1}$로 각각 추정 되었으며, 이를 통해 확인된 순간어획사망계수(F)는 $0.061\;year^{-1}$로 확인되었다.

• The Korean Journal of Physiology and Pharmacology
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• 제19권2호
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• pp.159-165
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• 2015

Input signals originating from baroreceptors and vestibular receptors are integrated in the rostral ventrolateral medulla (RVLM) to maintain blood pressure during postural movement. The contribution of baroreceptors and vestibular receptors in the maintenance of blood pressure following hypotension were quantitatively analyzed by measuring phosphorylated extracellular regulated protein kinase (pERK) expression and glutamate release in the RVLM. The expression of pERK and glutamate release in the RVLM were measured in conscious rats that had undergone bilateral labyrinthectomy (BL) and/or sinoaortic denervation (SAD) following hypotension induced by a sodium nitroprusside (SNP) infusion. The expression of pERK was significantly increased in the RVLM in the control group following SNP infusion, and expression peaked 10 min after SNP infusion. The number of pERK positive neurons increased following SNP infusion in BL, SAD, and BL+SAD groups, although the increase was smaller than seen in the control group. The SAD group showed a relatively higher reduction in pERK expression when compared with the BL group. The level of glutamate release was significantly increased in the RVLM in control, BL, SAD groups following SNP infusion, and this peaked 10 min after SNP infusion. The SAD group showed a relatively higher reduction in glutamate release when compared with the BL group. These results suggest that the baroreceptors are more powerful in pERK expression and glutamate release in the RVLM following hypotension than the vestibular receptors, but the vestibular receptors still have an important role in the RVLM.

• Korean Journal of Acupuncture
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• 제28권1호
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• pp.91-100
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• 2011

Objectives : To classify needling or moxibustion-prohibited acupoints in Emergency Formulas Worth a Thousand in Gold (EFWTG) and Supplement to the Formulas Worth a Thousand in Gold (SFWTG). Methods : We found needling or moxibustion-prohibited acupoints in EFWTG and SFWTG, then investigated the influences of needling or moxibustion-prohibited acupoints on A-B Classic of Acupuncture and Moxibustion. Results : In EFWTG, the needling-prohibited points were LI13, ST17, BL56, TE8, CV8, CV15 and GV24. Acupoints needed careful needling were LU2, ST12, KI2, KI7, TE19, GB3 and jwagak. The moxibustion-prohibited points were LU3, LU8, ST1, ST8, ST9, ST17, ST32, ST33, BL6, BL30, TE18, TE23, GB33, GB42, CV5, CV15, GV6, GV15, GV16 and GV17. Acupoints needed careful moxibustion were ST7, ST30, TE21 and GB22. In SFWTG, the needling-prohibited points were LU2, LI13, ST12, ST17, ST32, BL56, KI2, KI7, TE8, TE19, GB3, CV8, CV15, GV24 and jwagak. The moxibustion-prohibited points were LU3, LU8, ST1, ST7, ST8, ST9, ST17, ST30, ST32, ST33, BL6, BL30, TE18, TE23, GB22, GB33, GB42, CV5, CV15, GV6, GV15, GV16, GV17 and ijung. Conclusions : There were 7 needling-prohibited points, 7 acupoints needed careful needling, 20 moxibustion-prohibited points, and 4 acupoints needed careful needling in EFWTG, and 15 needling-prohibited points and 24 moxibustion-prohibited points in SFWTG. The needling or moxibustion-prohibited acupoints in A-B Classic of Acupuncture and Moxibustion had a strong influence on those in the two literatures.

• Childhood Kidney Diseases
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• 제9권2호
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• pp.275-281
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• 2005

저자들은 생체신장이식을 받은 후 발열과 빈혈을 주소로 내원한 2명의 환아에서 혈청 PCR을 통해 PV B19 감염을 진단한 후 면역글로불린 정맥투여로 싱공적으로 치료하고 재발 없이 관찰중인 2례를 경험하였기에 보고하는 바이다.

• Journal of Acupuncture Research
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• 제23권3호
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• pp.1-19
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• 2006

Objectives : This study was carried out to determine the effects of Gamidokwalgisaeng-tang(GDS) oral administration and electro-acupuncture at $BL_{52}$ & $GB_{39}$ on the postmenopausal osteoporosis. Methods: In order to study the effects of the Gamidokwalgisaeng-tang(GDS) oral administration and electro-acupuncture at $BL_{52}$, $GB_{39}$ on osteoporotic rats induced by ovariectomy, body weight, femur weight, uterine weight, serum level of osteocalcin, alkaline phosphatase(ALP), cholesterol, triglyceride, estradiol, androstenedione, testosterone and urinary excretions of calcium & phosphorus were measured. Results : 1. Body weight in all experimental group decreased significantly in comparison with ovariectomized group(OVX). 2. The weight of femur compared with body increased significantly in GDS oral administration and combination treatment group in comparison with ovariectomized group(OVX). 3. Uterine endometrial morphology is caused by ovariectomy and the weight of uterus decreased significantly in control and all experimental group in comparison with sham. 4. The serum level of osteocalcin decreased in all experimental group in comparison with OVX, but significantly in electro-acupuncture and combination treatment group. 5. The serum alkaline phosphatase(ALP) activity decreased in electro-acupuncture and combination treatment group in comparison with OVX, but only significantly in electro-acupuncture group. 6. The serum level of cholesterol increased significantly in OVX in comparison with sham and decreased in all experimental group in comparison with OVX, not insignificantly. The serum level of triglyceride increased in all experimental group in comparison with OVX, not insignificantly. 7. Urinary excretions of calcium and phosphorus decreased significantly in all experimental group in comparison with OVX. Conclusion : We suggest that GDS oral administration and electro-acupuncture at $BL_{52}$ & $GB_{39}$ are available for prevention and curing about the postmenopausal osteoporosis.

• Korean Journal of Acupuncture
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• 제27권2호
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• pp.57-70
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• 2010

Objectives : To investigate the meaning and the importance of needling or moxibustion- prohibited acupoints in Chimgugapeulgyeong(鍼灸甲乙經). Methods : We found needling or moxibustion-prohibited acupoints in Chimgugapeulgyeong, then investigated the causes of the prohibitions from the various literatures and the anatomical structures near the acupoints. Results : In Chimgugapeulgyeong, the needling and moxibustion-prohibited points were ST9, ST17, ST32, CV5, and CV15. The needling-prohibited points were LU2, LI13, ST12, BL56, KI2, KI7, TE8, TE19, GB3, CV8, GV24, and jwagak(左角). The moxibustion-prohibited points were LU3, LU8, ST1, ST7, ST8, ST30, ST33, BL5, BL6, BL15, BL30, TE18, TE21, TE23, GB22, GB33, GB42, GV6, GV15, GV16, GV17 and GV25. The major cause of developing prohibited needling or moxibustion was due to the possibility to damage vessels or organs near them; other causes were side effects brought by applying wrong stimulating method or inducing women sterilized. Conclusions : The prohibition of needling or moxibustion on the points found in Chimgugapeulgyeong had acceptable causes. Therefore the techniques of needling or moxibustion on the acupoint should be performed with care.

• Journal of Acupuncture Research
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• 제28권5호
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• pp.39-55
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• 2011

Objectives : Inchinohryungsan has been used for treatment of hepatobiliary diseases. This study was designed to investigate the effect of Inchinohryungsan pharmacopuncture on hepatocellular carcinoma in rats. Sprague Dawley(SD) rats of the control and experimental groups received intraperitoneal injection of 50 mg/kg DEN, weekly for 12 weeks. Methods : Rats were divided into 5 groups. Normal group was not induced hepatocellular carcinoma and not treated. Control group was induced hepatocellular carcinoma and injected with Inchinohryungsan pharmacopuncture into the root of tail. Experimental groups were induced hepatocellular carcinoma. BL group was injected with Inchinohryungsan pharmacopuncture into the $BL_{18}$ and $LR_{14}$, BG group was injected into the $BL_{19}$ and $GB_{24}$ and CSC group was injected into the $CV_{12}$, $ST_{25}$ and $CV_4$. Thereafter, the changes of the body weight, the liver weight and the weight of liver/100g body weight, WBC, neutrophil, lymphocyte and the activities of AST, ALT, ALP, LDH, AFP and SOD were measured. And gross anatomy, light and electron microscopy were performed. Results : The significant results were as follows, 1. The activities of LDH were significantly decreased in CSC group compared with control group. 2. The activities of AFP were significantly decreased in the BL, BG, CSC groups compared with control group. 3. The activities of SOD were increased in the BL, BG, CSC groups compared with control group and CSC group was significantly increased than normal group. 4. According to the gross anatomical observation, the control and BL, BG, CSC groups showed multi-nodular hepatocellular carcinoma. But the size and numbers of the hepatocellular carcinoma in experimental groups were smaller than control group. 5. The numbers of hepatic p53 positive cells were decreased in the BL, BG groups compared with control group. 6. According to the light and electron microscopical observation, the BL, BG and CSC groups were mildly improved than control group in morphological and histopathological changes. Conclusions : These results suggested that Inchinohryungsan pharmacopuncture may have some effects on hepatocellular carcinoma induced by DEN in rats.