• Polymer(Korea)
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• v.37 no.1
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• pp.28-33
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• 2013

Zaltoprofen, a propionic acid derivative non-steroidal anti-inflammatory drug, was known to have powerful inhibitory effects on acute, subacute and chronic inflammation. For initial release and sustained release, the microspheres were prepared using an emulsion-solvent evaporation method like an O/W emulsion method with varying the ratio of zaltoprofen-loaded polyoxalate (POX)/PLGA micropheres. The morphology of the microspheres was confirmed by scanning electron microscopy. The crystallinity of microspheres was analyzed by X-ray diffraction and differential scanning calorimeter. Fourier transform infrared spectroscopy was used to analyze the chemical structure of microspheres. The increased ratio of POX microspheres affected the initial drug release, and the sustained release of drug was influenced by ratio of PLGA microspheres. In this study, the initial release behavior of zaltoprofen can be controlled by the ratio of POX/PLGA microspheres.

• Journal of Pharmaceutical Investigation
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• v.38 no.2
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• pp.111-117
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• 2008

To overcome the solubility of poorly water-soluble drug, the formation of solid dispersion using a spray-dryer with polymeric material, that can potentially enhance the dissolution rate extend of drug absorption was considered in this study. $Eudragit^{(R)}$ E100 as carrier for solid dispersion is acrylate copolymer that soluble in acidic buffer solutions (below pH 5.0). It was used to increase dissolution of atorvastatin calcium as a water-insoluble drug in acidic environments. In this study, a spray-dryer was used to prepare solid dispersion of atorvastatin calcium and $Eudragit^{(R)}$ E100 for purpose of improving the solubility of drug. Atorvastatin calcium and $Eudragit^{(R)}$ E100 were dissolved in ethanol and spray-dryed. DSC and XRD were used to analyze the crystallinity of the sample. It was found that atorvastatin calcium is amorphous in the $Eudragit^{(R)}$ E100 solid dispersion. FT-IR was used to analyze the salt formation by interaction between atorvastatin calcium and $Eudragit^{(R)}$ E100. Comparative dissolution study exhibited better dissolution characteristics than the commercial drug ($Lipitor^{(R)}$) as control. The dissolution rate of atorvastatin calcium was markedly increased in solid dispersion system in simulated gastric juice (pH 1.2). This study proposed that this solid dispersion system improved the bioavailability of poorly water-soluble atorvastatin calcium.

• Polymer(Korea)
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• v.35 no.4
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• pp.289-295
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• 2011

Biomaterials for retinal tissue engineering must demonstrate several critical features for potential utility, including mechanical integrity, biocompatibility, and slow biodegradation. Silk film biomaterials were designed and characterized to meet these functional requirements. We prepared natural/synthetic hybrid silk/PLGA films using 0, 10, 20, 40, and 80 wt% of silk by a solvent evaporation method. MIT assay was used to confirm the number of cells attached on film at 1, 2, and 3 days, respectively. The morphology of cellular adhesion on films was also confirmed by scanning electron microscope (SEM). RT-PCR was conducted to confrrm mRNA expression of retinal pigment epithelitun (RPE) using RPE65 as a RPEs marker and the expression of cytokeratin were determined by immunofluorescence staining. We confirmed that the silk/PLGA film of 20~40 wt% silk was superior for the adhesion and proliferation of RPEs.

• Journal of Biosystems Engineering
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• v.5 no.2
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• pp.15-25
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• 1980

본 연구는 현재 국내 농촌에서 문제시되고 있는 벼의 건조와 저장방법을 개선하기위한 한 가지 방법으로써 Grain bin의 이용에 따른 기술적인 적용가능성을 구명하는데 있었으며 건조열원으로서는 상온공기와 Solar collector 에 의한 보충가열공기를 사용하였다. 건조시험에서는 벼의 건조속도, 층별함수율의 변화, 동력소모량, 도청수율 등을 측정 비교하였으며 건조가 완료된 후에는 저장시험도 아울러 실시하였다. 본 시험을 통하여 얻은 결과는 다음과 같다. 1. 본시험에 사용된 Solar Collector 는 집열면적이 $27.7m^2M$의 Flat-plate 형식이며 내부에 태양열의 저장모체로서 약 $7m^2M$의 검은 돌을 사용하였다. Collector 의 효율은 35%이었으며 Collector를 통과하여 Bin으로 들어가는 공기의 온도는 외기온에 비하여 주간에는 약 $4^\circ C$, 야간에는 약 $8^\circ C$, 정도 상승된 것으로 나타났다. 2. 상온공기와 Collector를 이용한 건조험결과 안전저장함수율에 도달하는 데 약 7일과 약 5일이 소요되었다. 3. 태양열 건조는 상온통풍건조에 비하여 곡물층간의 함수율차이가 약간 크게 나타났으나 건조속도가 빠를뿐만 아니라 동력소모량도 적은 것으로 분석되었다. 4. 건조시험이 완료된 직후 이차에 걸쳐 Bin 내에서 저장시험을 실시한 결과 저장기간중 벼의 안전보전이 가능했으며 평균함수율이 12.0~14.5%범위에서 유지되었다.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.320-323
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• 2008

In this paper, electro-optical characteristic of Nematic Liquid crystal (LC) with varying temperature in different LCD modes, namely Fringe Field Switching (FFS), In-plane switching (IPS), and Patterned Vertical Alignment (PVA) modes are investigated and compared. Electro optic me asurements suggest that rate of change of transmission with temperature in FFS mode was lowest and much more thermally stable as compared to IPS and PVA m odes. However the electro-optical characteristic of patterned vertical alignment (PVA) mode was most affected by changing temperature. The measured threshold voltage was found to be much more thermally stable in FFS and IPS modes than that of PVA mode.

• Journal of Biosystems Engineering
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• v.13 no.2
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• pp.28-37
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• 1988

This study was conducted to construct the soil bin system and associated microcomputer-based data acquisition system which is to be used for the effective evaluation of wheel performance. The soil bin system consists of four main parts; soil bin, carriage drive system, test carriage and soil processing carriage. The test carriage was constructed to measure the five performance parameters of testing wheels; pulling forte, motion resistance, sinkage and rotational speed of test wheel, and speed of test carriage. The test wheel is powered by a hydraulic system up to 8 ps. Soil processing carriage was designed to provide uniform test soil condition across the toil bin, and reproduction of soil conditions found satisfiable. The data acquisition system consists of APPLE II PLUS microcomputer, strain amplifier, I/O interface, A/D converter, digital counter and various transducers. It takes about 0.86 seconds to measure a set of performance parameters and store on the floppy disk simultaneously. Series of experiment showed that this system can be used effectively for evaluating the wheel performance associated with soil.

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.629-632
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• 2009

We have proposed a novel viewing angle controllable display of in-plane switching (IPS) mode with single panel. One pixel of this device is divided to two regions, in which main pixel shows image and sub pixel for viewing angle control. In initial state, the liquid crystal of sub pixel is homogeneous aligned on substrate for wide viewing angle mode. On the other hand, after applying voltage, the liquid crystal of sub pixel tilts up for narrow viewing angle mode. The proposed device has advantage for the function for simple manufacturing process and good viewing angle control with single panel.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.4
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• pp.63-72
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• 2022

The study applied the non-financial dimensions of the Balanced Scorecard (customer dimension, internal processes dimension, learning, and growth dimension). It was done to evaluate performance and measure the effectiveness of these dimensions on performance evaluation at College of Science and Humanities Studies: Al Aflaj, Prince Sattam Bin Abdulaziz University. The researchers used the descriptive analytical approach to conduct the study to find the effect of these dimensions. Data was collected from the college staff and administrators; 120 questionnaires were distributed, out of which 112 were collected. The questionnaire data were analyzed using exploratory (EFA) and confirmatory factor analysis (CFA), hypotheses were tested using the structural equation modeling (SEM) through the (Spss) and (Amos) software. The study finding showed that the balanced scorecard had a positive contribution in evaluating the performance of the College of Science and Humanities Studies: Al Aflaj, Prince Sattam Bin Abdulaziz University through the dimensions of customers and internal processes, and the study finding revealed that the balanced scorecard has no contribution at performance evaluating the College of Science and Humanities Studies: Al Aflaj, Prince Sattam Bin Abdulaziz University through the dimension of learning and growth.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.46 no.2
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• pp.1-12
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• 2023

To make semiconductor chips, a number of complex semiconductor manufacturing processes are required. Semiconductor chips that have undergone complex processes are subjected to EDS(Electrical Die Sorting) tests to check product quality, and a wafer bin map reflecting the information about the normal and defective chips is created. Defective chips found in the wafer bin map form various patterns, which are called defective patterns, and the defective patterns are a very important clue in determining the cause of defects in the process and design of semiconductors. Therefore, it is desired to automatically and quickly detect defective patterns in the field, and various methods have been proposed to detect defective patterns. Existing methods have considered simple, complex, and new defect patterns, but they had the disadvantage of being unable to provide field engineers the evidence of classification results through deep learning. It is necessary to supplement this and provide detailed information on the size, location, and patterns of the defects. In this paper, we propose an anomaly detection framework that can be explained through FCDD(Fully Convolutional Data Description) trained only with normal data to provide field engineers with details such as detection results of abnormal defect patterns, defect size, and location of defect patterns on wafer bin map. The results are analyzed using open dataset, providing prominent results of the proposed anomaly detection framework.

• International Journal of Computer Science & Network Security
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• v.23 no.6
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• pp.91-98
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• 2023

The rapid increase in the use of new technology known as 'blockchain technologies' has addressed many challenges in different areas and provided benefits to users, in this paper we discuss the field of supply chains, improve confidence and transparency between participants and stakeholders significantly also in this paper we Compare between different blockchain frameworks focusing on most popular frameworks. Moreover, we proposed a model in the supply chain using a blockchain framework, the proposed supply chain model included many different resources that help to exchange information over the network. The proposed model also includes smart contracts that maintain all rules for transactions. using blockchain technology information such as transaction details, time and money are recorded and stored within the system from the beginning of the transaction entry.