• Journal of Nutrition and Health
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• 제31권4호
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• pp.756-766
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• 1998

The objectives of this study were to examine the growth pattern and hair trace element contents of healthy infants who were fed breast milk(BF infant) and formula (FF infant) during the first 6 months and its relationship to intake of trace elements. Bimonthyl anthropometric measurements were obtained on 32 infants through 6 months of age. Mean calculated energy, iron, zinc and copper intake from breast milk at 2 months of age were 432.4kcal/d, 0.19mg/d, 1.18mg/d and 0.22mg/d. The values obtained from formular were543.7kcal/d, 6.68mg/d , 2.82mg/d and 0.33mg/d , respectively. In spite of the significantly lower intake of energy and trace elements in BF infants than in FF infants, BF infants showed growth above the average Kroean infant standard growth rate and showed no significant growth rate difference or hair trace element content. Hair iron content in the BF infants at 6 mo. of age was positively related to birth weight and iron intake at 2 mo. of age. In contrast, hair zinc and copper content in the FF infants at 6 mo. of age as negatively related to height increment and weight increment during 6 months, respectively. These results support the suggesting that BF infant's higher iron, zinc and copper intake is attributed to the superior bioabailability of these trace elements from breast milk.

• 한국자원식물학회지
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• 제30권5호
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• pp.556-564
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• 2017

중부지역에서 감자와 콩의 안전다수확 작부체계를 위해서는 전작물인 봄감자의 조기 파종과 초기생육을 위한 적정 토양 온도의 확보가 결정적 요인으로 작용한다. 따라서 본 실험은 비닐 피복의 종류별 지온상승효과와 이에 따른 감자의 생육과 수량에 미치는 영향을 검토하였다. 봄감자 초기생육기간인 파종부터 덧 필름 제거 시까지 처리구별 평균지온은 무피복구(NM) $13.8^{\circ}C$에 비하여 투명필름+덧 필름 > 투명필름 > 흑색필름+덧 필름 > 흑색필름 순으로 각각 $20.3^{\circ}C$ > $18.5^{\circ}C$ > $16.1^{\circ}C$ > $14.5^{\circ}C$ 높았다. 일중 시간대별 온도변화를 보면, 기온이 낮은 오후 6~9시부터 익일 오전 11~12시까지는 BF의 지온이 NM보다 낮았던 반면, 기온이 높은 오전 10~12시부터 오후 6~9시까지는 NM의 지온이 BF의 지온보다 높았다. 감자 싹의 지상부 출현은 TF+ATF > TF > BF+ATF > BF 순으로 각각 15일 > 18일 > 20일 > 22일 빨랐으며, TF+ATF 처리구의 경우 무처리구(NM) 24일에 비하여 무려9일 이나 빨리 감자 싹이 출현되었다. 수확 10일 전 처리구간 감자 지하부 건물중 차이는 TF > TF+ATF > BF+ATF > BF > NM 순이었으며, 통계적으로 유의성 있게 높았다. 이는 처리구별 지온상승효과와 거의 일치하였다. 감자 수량은 대조구인 NM 처리의 $2,805kg\;10a^{-1}$ 비하여 TF에서 41%, TF+ATF 처리는 37% 및 BF+ATF 처리는 2% 증수되었고, BF 처리는 유사하였다. 본 실험은 비닐피복으로 지온을 높여 생육을 증진시키고자 하는데 목표가 있었다. 본 실험의 결과 봄감자 안전다수확 재배를 위해서는 생육초기 지온상승과 생육촉진효과가 높고 조기파종과 출현을 촉진하여 보다 긴 생육기간을 확보 할 수 있는 투명필름 피복이 효과적이고, 덧 필름 피복은 기상조건에 따라 경제성을 고려하여 선택을 하는 것이 좋은 것으로 판단되어진다.

• Journal of Animal Science and Technology
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• 제57권1호
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• pp.3.1-3.6
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• 2015

This study investigated the effects of feeding by-product feed (BF)-based silage on the behavior of growing Hanwoo heifers. Twelve Hanwoo heifers (13.2 months-old, 315 kg body weight; four heifers per pen) were assigned to three diets: a rice straw (RS) diet (concentrate mix and free access to RS), a RS and BF-based silage (RSBFS) diet (concentrate mix and free access to RS and BF-based silage), and a BF-based silage (BFS) diet (concentrate mix and free access to BF-based silage). Behavior was recorded for 5 days using camcorders. Compared to the RS group, the BFS group showed 21.7% higher dry matter intake, shorter feeding, rumination, and chewing times, as well as longer resting time (p < 0.05). Although all groups exhibited similar drinking, urination, and defecation frequencies, the BFS group exhibited higher feeding rates, rumination efficiency, and chewing efficiency than the RS group (p < 0.05). Compared to the BFS group, the RSBFS group showed higher $peNDF_{8.0}$ intake (15.2% vs. 25.0% dry matter intake), longer feeding and sitting times, lower defecation frequency (p < 0.05), and similar rumination efficiency. In conclusion, complete replacement of conventional RS with BF-based silage reduced rumination and chewing activity in growing Hanwoo heifers, and BF-based silage feeding with large-particle straw is an effective approach in improving heifer behavior.

• Parasites, Hosts and Diseases
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• 제53권6호
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• pp.675-682
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• 2015

The effects of diclazuril on the bursa of Fabricius (BF) structure and secretory IgA (SIgA) expression in chickens infected with Eimeria tenella were examined. The morphology of the BF was observed by hematoxylin and eosin staining, while ultrastructural changes were monitored by transmission electron microscopy. E. tenella infection caused the BF cell volumes to decrease, irregularly arranged, as well as, enlargement of the intercellular space. Diclazuril treatment alleviated the physical signs of damages associated with E. tenella infection. The SIgA expression in BF was analyzed by immunohistochemistry technique. The SIgA expression increased significantly by 350.4% (P<0.01) after E. tenella infection compared to the normal control group. With the treatment of diclazuril, the SIgA was relatively fewer in the cortex, and the expression level was significantly decreased by 46.7% (P<0.01) compared with the infected and untreated group. In conclusion, E. tenella infection in chickens induced obvious harmful changes in BF morphological structure and stimulated the expression of SIgA in the BF. Diclazuril treatment effectively alleviated the morphological changes. This result demonstrates a method to develop an immunological strategy in coccidiosis control.

• 한국가금학회지
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• 제7권2호
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• pp.18-27
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• 1980

IBDV는 양계업이 전업화된 모든지역에서 발생하고 있다. 이 질병의 임상증상은 매우 특징적이기도 하지만 IBDV 감염시의 닭의 연령 또는 바이러스의 병원성에 따라 임상증상 업이 내과 하기도 한다. IBDV에 의한 BF의 종장이나 출혈성 병변은 감염 후 짧은 기간에만 관할되며 질병이 경과함에 따라 BF는 위축된다. IBDV는 감염력이 극히 높으며, 오염된 계분, 사료, 물 등에 의하여 전파된다. 이 바이러스는 외계 환경에 대하여 극히 높은 저항성을 갖고 있으며 Ribovirus군의 Diplorna 바이러스로서 크기는 55-60nm이다. IBDV는 계태아나 계태아 조직 또는 감수성이 있는 닭의 BF에서 용이하게 증식시킬 수 있다. agar gel을 사용한 면역 확산법은 IBDV 감염을 진단할 수 있는 가장 간편한 방법이다. IBDV에 대한 항체는 감염 후 1주일 후부터 증명되며 장기간 지속된다. 감수성 계군일 경우 높은 역가의 항체형성이나 지속은 계군의 연령에 비례한다. IBDV에 대한 모체이행 항체는 critical age때의 병아리를 야외 감염으로부터 보호하여 준다. IBDV 단독 감염에 의한 IBD 피해는 경미한 것이지만 면역부전증에 의하여 유발되는 복합성 질병인 Inclusion body hepatitis, 전염성 빈혈, 괴저성 피부염 등은 닭의 생산성을 크게 저하시킨다.

• Biomolecules & Therapeutics
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• 제23권4호
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• pp.350-356
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• 2015

Functional dyspepsia (FD) is a prevalent idiopathic upper gastrointestinal (GI) disorder characterized by diverse symptomatology including epigastric pain or discomfort, postprandial fullness, and early satiety. Although its pathophysiological mechanisms have not yet been fully established, the available studies suggest that the etiology of FD is invariably multifactorial. Benachio-F$^{(R)}$ (BF) is a proprietary liquid formulation of 7 herbal extracts that has been proposed to address this multifactorial etiology using multi-drug phytotherapy. The pharmacological effects of BF, in comparison with those of two other herbal products (Whalmyungsu$^{(R)}$; WM and Iberogast$^{(R)}$; IB) were evaluated in rats. In a laparotomy-induced rat model of delayed GI transit, BF significantly accelerated the delayed gastric emptying caused by morphine, apomorphine, and cisplatin, and also significantly increased mean gastric transit, as compared to the control animals. BF markedly increased gastric accommodation in rats and produced higher gastric volume values than did the control treatment. The effects of BF were generally comparable or superior to those of WM and IB in these models. Furthermore, BF significantly stimulated biliary flow, as compared to the control treatment. These results indicated that BF might have great potential as an effective phytotherapeutic agent capable of reducing GI symptoms and increasing quality of life in FD patients.

• 멤브레인
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• 제27권3호
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• pp.226-231
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• 2017

이산화탄소 분리를 위해 이온성 액체/금속 산화물 복합막이 제조되었으며, 이온성 액체로서 1-butyl-3-methylimidazolium tetrafluoroborate ($BMIM^+BF_4{^-}$)와 금속산화물로서 $Al_2O_3$가 사용되었다. 13 nm의 $Al_2O_3$가 이온성 액체 $BMIM^+BF_4{^-}$에 도입되었을 때, 복합체 분리막의 성능은 $CO_2/N_2$ 선택도 30.5과 $CO_2$ 투과도 45.7 GPU로 관찰되었다. neat $BMIM^+BF_4{^-}$ 분리막의 성능($CO_2/N_2$ 선택도 5와 $CO_2$ 투과도 17 GPU)에 비해서 성능이 증가한 이유는 $Al_2O_3$의 옥사이드 층과 이온성 액체 내 자유로운 이온농도의 상승으로 인해 $CO_2$ 용해도가 상승한 것으로 확인되었다. 특히 $Al_2O_3$ 나노입자는 질소 기체에 대해서 장애물로서 작용함으로써 질소기체의 투과도가 감소하여 결과적으로 이산화탄소 분리 성능은 급격히 증가하였다.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제23권4호
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• pp.7-15
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• 2017

Purpose: The Korean government has implemented a Barrier Free Certification System since 2008 to create a secure and convenient environment for the socially disadvantaged. The drastic increase in the number of BF-certification facilities is expected due to the revision of the system and increasing the number of certification institutions. An analysis of individual evaluation items needs to be made for the BF-Certification with public confidence. Method: Korean standard, International Standard(ISO/FDIS 21542, 2011), German Standard(DIN 18040-1, 2010), Austrian Standard(${\ddot{O}}NORM$ B 1600, 2017) and Swiss Standard(Norm SIA 500 / SN 521 500, 2009) were investigated and analyzed. A comprehensive improvement plan is proposed by comparing details of the aforementioned standards and the evaluation items of BF-Certification. Results: Many problems arise in applying existing Barrier-free standards due to changes in population structure, environmental change and the use of powered wheelchairs. International standards are being improved to solve these problems. The korean standards also require improving of the Barrier Free Law and Certification System, which reflect these trends. In korean cases, standards such as the size of the doors (width and height), the Unobstructed Manoeuvring Space and Clear Space at the Latch side of the Door are required to improve standards in accordance with international standards. In addition, the expression of laws and evaluation items of BF-Certification should be clearly defined. And the application of visual contrast standards for the enhancement of perceptions presented in international standards should be considered. Implication: Barrier Free related legal standards and evaluation items of BF-Certification that are used in Korea are required to be revised in consideration of social and environmental changes. Comprehensive improvements should be made through detailed review.

• 문화기술의 융합
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• 제9권2호
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• pp.519-524
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• 2023

이 연구는 경기상황과 유사한 점프 동작이 포함된 배드민턴 기술 동작 시 근육의 활성도의 차이를 조사함으로써 효율적인 기술훈련을 위한 기초자료를 구성하기 위한 목적이다. 남자 배드민턴 선수 7명을 대상으로 하여 스매시, 드롭, 클리어 기술을 무선배정으로 실시하였으며, 3가지 기술 동작 시행 중 근전도를 측정하였다. 측정된 근전도는 RMS로 산출하였으며 일원분산분석을 실시하였다. 스매싱 동작의 근활성도는 부위에 따른 유의한 차이를 보이지 않았다. 드롭 동작에서 상지 근육 중 PM의 활성도는 BC, ECR보다 낮았으며, FCR의 활성도는 EC보다 낮았다. ECR의 활성도는 PM, FCR보다 높았다. 몸통 근육 중 ES의 활성도는 RF, GM보다 낮았다. 하지 근육 중 RF의 활성도는 ES, BF보다 높았다. 클리어 동작에서 상지 근육 중 TC의 활성도는 FCR보다 높았다. 몸통 근육 중 ES의 활성도는 BF보다 낮았다. 하지 근육 중 RF의 활성도는 BF보다 높았으며, BF의 활성도는 RF, GM보다 낮았다. GM의 활성도는 BF보다 높았다. 배드민턴 기술에 따른 근활성도는 FCR에서 스매시와 드롭 동작이 클리어 동작보다 높았으며, RA에서 클리어가 스매시, 드롭 동작보다 높았다. 종합하면, 배드민턴 경기 중 근육활동은 기술별 특성에 따라 다르게 나타나고 노쪽손목굽힘근은 스매시와 드롭, 배곧은근은 클리어 동작에 영향을 미칠 수 있을 것으로 사료된다.

• Journal of Microbiology and Biotechnology
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• 제28권12호
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• pp.1999-2008
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• 2018

The compound 2,5-furandicarboxylic acid (FDCA), an important bio-based monomer for the production of various polymers, can be obtained from 5-hydroxymethylfurfural (HMF). However, efficient production of FDCA from HMF via biocatalysis has not been well studied. In this study, we report the identification of key genes that are involved in FDCA synthesis and then the engineering of Raoultella ornithinolytica BF60 for biocatalytic oxidation of HMF to FDCA using its resting cells. Specifically, previously unknown candidate genes, adhP3 and alkR, which were responsible for the reduction of HMF to the undesired product 2,5-bis(hydroxymethyl)furan (HMF alcohol), were identified by transcriptomic analysis. Combinatorial deletion of these two genes resulted in 85.7% reduction in HMF alcohol formation and 23.7% improvement in FDCA production (242.0 mM). Subsequently, an aldehyde dehydrogenase, AldH, which was responsible for the oxidation of the intermediate 5-formyl-2-furoic acid (FFA) to FDCA, was identified and characterized. Finally, FDCA production was further improved by overexpressing AldH, resulting in a 96.2% yield of 264.7 mM FDCA. Importantly, the identification of these key genes not only contributes to our understanding of the FDCA synthesis pathway in R. ornithinolytica BF60 but also allows for improved FDCA production efficiency. Moreover, this work is likely to provide a valuable reference for producing other furanic chemicals.