• Journal of Life Science
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• v.25 no.4
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• pp.473-480
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• 2015

The endoplasmic reticulum (ER) in the eukaryotic cells is the first compartment in the secretory pathway. Almost secretory proteins and membrane proteins are secreted through the ER, in which post-translational modifications occur via diverse signals from the ER lumen to the cytoplasm and nucleus. Only then are correctly-folded proteins secreted to the outside cells. Unfolded proteins that accumulate in the ER cause a kind of intracellular stress, ER stress, and activate an unfolded protein response (UPR) system. The 3 major transducers of the UPR are inositol requiring 1 (IRE1), PKR-like ER kinase (PERK) and activating transcription factor 6 (ATF6), all of which are ER transmembrane proteins. Recently, novel types of a new ATF6 family have been identified. Those commonly have an ER-transmembrane domain, a transcription-activation domain and a basic leucine zipper (bZIP) domain―Luman, OASIS, BBF2H7, CREBH and CREB4. Each factor functions by regulating the UPR in specific organs and tissues. Although the detailed molecular mechanisms of OASIS family members are unknown, in this study we comprehensively introduce these molecular signals.

• Journal of information and communication convergence engineering
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• v.12 no.4
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• pp.228-236
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• 2014

One of major purposes of these standard technologies is to ensure interoperability between entities from different vendors and enable interworking between various technologies. As interoperability and interworking are essential for machine-to-machine communications (M2M) and Internet of Things (IoT) for them to achieve their ultimate goal, i.e., things to be connected each other, multiple standards organizations are now working on development M2M/IoT related specifications. This paper reviews the current activities of some of the most relevant standardization bodies in the area of M2M and IoT: third-generation partnership project (3GPP) core and radio network aspects, broadband forum, and oneM2M. The major features and issues being focused upon in these standards bodies are summarized. Finally, some key common trends among the different bodies are identified: a common service layer platform, new technologies mitigating an explosive growth of network traffic, and considerations and efforts related to the development of device management technologies.

• Electronics and Telecommunications Trends
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• v.27 no.2
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• pp.89-98
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• 2012

광통신 기술의 발달과 인터넷 서비스 수요의 급격한 증가로 2000년대 초반부터 광가입자망 연구 및 상용화가 이루어졌다. 최근에는 스마트폰 등 모바일 단말의 확산과 IPTV의 수요 증대에 따른 폭발적 트래픽 증가에 대처하기 위하여 친환경, 에너지 절감형 차세대 초고속 대용량 광가입자망 기술에 대한 요구가 증대되고 있다. 차세대 광가입자망은 국내뿐 아니라 국외에서도 다양한 프로젝트를 통해 전송 거리, 분기 수 및 전송 용량을 늘리는 방향으로 연구개발이 진행되고 있으며 기존의 TDM, WDM(Wavelength Division Multiplexing) 기술뿐만 아니라 무선 통신에서 사용되던 OFDM(Orthogonal Frequency-Division Multiplexing) 등의 신호변조 기법들을 광가입망 기술에 접목하려는 시도들이 진행되고 있다. 이와 같은 광가입자망 기술들은 ITU-T, IEEE, IEC뿐만 아니라 FSAN(Full Service Access Network), BBF(Broadband Forum), MSF(Multi-service Forum) 등의 표준화 단체에서 활발히 국제표준화가 진행 중이다. 본고에서는 현재 진행되고 있는 차세대 광가입자망 기술에 대한 국내 외 기술개발 현황 및 표준화 현황을 살펴보고자 한다.

• The Journal of Advanced Prosthodontics
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• v.9 no.5
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• pp.335-340
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• 2017

PURPOSE. Bacterial adhesion on provisional crown materials retained for a long time can influence the duration for which permanent prosthetic restorations can be healthily worn in the oral cavity. The aim of this study was to compare seven different commonly used provisional crown materials with regard to Streptococcus mutans and Candida albicans surface adhesion. MATERIALS AND METHODS. For each group, twenty specimens of the provisional fixed prosthodontic materials TemDent ($Sch{\ddot{u}}tz$), Imident (Imicryl), Tab 2000 (Kerr), Structur Premium (Voco), Systemp (Ivoclar Vivadent), Acrytemp (Zhermack), and Takilon-BBF (Takilon) were prepared (diameter, 10.0 mm; height, 2.0 mm). Surface roughness was assessed by atomic force microscopy. Each group was then divided into 2 subgroups (n=10) according to the microbial suspensions used: S. mutans and C. albicans. The specimens were incubated at $37^{\circ}C$ with S. mutans or C. albicans for seven days. Bacterial adherence on surfaces was assessed using the 2,3-bis[2-methyloxy-4-nitro-5-sulfophenyl]-2H-tetrazolium-5-carboxanilide (XTT) assay. RESULTS. S. mutans showed maximum adhesion to Structur, followed by Systemp, Acrytemp, Takilon, Tab 2000, Imident, and TemDent (P<.05). The highest vital C. albicans adhesion was noted on Takilon, followed by Imident and Tab 2000; the lowest adhesion was noted on Systemp (P<.05). CONCLUSION. The materials showed significant differences in the degree of bacterial adhesion. C. albicans showed higher surface adhesion than S. mutans on provisional crown and fixed partial denture denture materials.

• Journal of Biomedical Engineering Research
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• v.34 no.1
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• pp.24-33
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• 2013

To enhance the speech perception of hearing aid users in noisy environment, most hearing aid devices adopt various beamforming algorithms such as the first-order differential microphone (DM1) and the two-stage directional microphone (DM2) algorithms that maintain sounds from the direction of the interlocutor and reduce the ambient sounds from the other directions. However, these conventional algorithms represent poor directionality ability in low frequency area. Therefore, to enhance the speech perception of hearing aid uses in low frequency range, our group had suggested a fractional delay subtraction and integration (FDSI) algorithm and estimated its theoretical performance using computer simulation in previous article. In this study, we performed a KEMAR test in non-reverberant room that compares the performance of DM1, DM2, broadband beamforming (BBF), and proposed FDSI algorithms using several objective indices such as a signal-to-noise ratio (SNR) improvement, a segmental SNR (seg-SNR) improvement, a perceptual evaluation of speech quality (PESQ), and an Itakura-Saito measure (IS). Experimental results showed that the performance of the FDSI algorithm was -3.26-7.16 dB in SNR improvement, -1.94-5.41 dB in segSNR improvement, 1.49-2.79 in PESQ, and 0.79-3.59 in IS, which demonstrated that the FDSI algorithm showed the highest improvement of SNR and segSNR, and the lowest IS. We believe that the proposed FDSI algorithm has a potential as a beamformer for digital hearing aid devices.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.12 no.11
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• pp.2077-2082
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• 2008

Recent the advanced technologies in medical imaging such as magnetic resonance imaging (MRI) and computed tomography (CT) make doctors improve the diagnostic skill with detailed anatomical information. In general, it is necessary to get a number of MRI images in order to obtain more detail information. However, the performance of MRI machines of privately run hospitals is not good and thus we may obtain only a few of MRI images. If 3D surface reconstruction is accomplished with a few slices, then it generates 3D surface of poor qualify. This paper propose a way to Set a 3D surface of high quality from a few of number of slices. First of all, our algorithm detects the boundary of tissues which we want to reconstruct as a 3D object and find out the set of vortices on the boundary. And then we generate a 3D implicit surface to interpolate the boundary points by using radial basis function. Lastly, we render the 3D implicit surface by using Marching cube algorithms.

• Proceedings of the Korean Society of Food Hygiene and Safety Conference
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• 2002.05a
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• pp.127-131
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• 2002

Migration of di-(ethylhexyl)phthalate (DEHF) from PVC food packaging materials detected plasticizer into food simulanting solvents(4% Acetic acid, 8% Ethanol, 50% Ethanol, 95% Ethanol, Heptane) were studied. For executing this study ,2 PVC food packaging materials detected DEHP were used. Analysis was by GC-FID and GC-MSD(selected ion monitoring) for DEHP, and optimized for quantification of plasticizer. The recovery of DEHP into food simulanting solvents were min. 87.4${\pm}$ 3.6 ∼ max. 109.9 ${\pm}$ 10.7% respectively. Following exposure to food simulants 95% Ethanol for 24hours at 60$^{\circ}C$ the migration results of 1020.90 ${\pm}$ 10.15$\mu\textrm{g}$/g, 563.54 ${\pm}$ 5.60$\mu\textrm{g}$/dm$^2$and 73.51 ${\pm}$ 5.09$\mu\textrm{g}$/g 149.22 ${\pm}$ 10.34$\mu\textrm{g}$/dm$^2$were detected from the container for lunch and for stock fish respectively.