• Title/Summary/Keyword: BAT2

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Characterization of bat coronaviruses: a latent global threat

  • Fang, Manxin;Hu, Wei;Liu, Ben
    • Journal of Veterinary Science
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    • v.22 no.5
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    • pp.72.1-72.15
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    • 2021
  • It has been speculated that bats serve as reservoirs of a huge variety of emerging coronaviruses (CoVs) that have been responsible for severe havoc in human health systems as well as negatively affecting human economic and social systems. A prime example is the currently active severe acute respiratory syndrome (SARS)-CoV2, which presumably originated from bats, demonstrating that the risk of a new outbreak of bat coronavirus is always latent. Therefore, an in-depth investigation to better comprehend bat CoVs has become an important issue within the international community, a group that aims to attenuate the consequences of future outbreaks. In this review, we present a concise introduction to CoVs found in bats and discuss their distribution in Southeast Asia. We also discuss the unique adaptation features in bats that confer the ability to be a potential coronavirus reservoir. In addition, we review the bat coronavirus-linked diseases that have emerged in the last two decades. Finally, we propose key factors helpful in the prediction of a novel coronavirus outbreak and present the most recent methods used to forecast an evolving outbreak.

Understanding and Improvement of the K-BREF (Korea BAT reference documents) for the Corrugated Cardboard Manufacturing Industry (골판지원지 제조업 최적가용기법 기준서의 이해와 개선사항)

  • Seo, Kyungae;Kim, Eunseok;Kim, Gahee;Khan, Jongbeom;Hong, Sukyoung;Kang, Philgoo
    • Journal of Environmental Science International
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    • v.29 no.5
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    • pp.559-573
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    • 2020
  • The purpose of this study analyzed the overview of corrugated cardboasrd manufacturing industry and then provide direction for improvement. The BREF (BAT reference document) is an important reference for licensees and officer, including the best available techniques for the industry and achievable environmental performance, technical characteristics, and economic information. In the corrugated cardboard manufacturing process, wastewater pollutants are generated throughout the production process, and water is used in the dissociation and aging process. Atmospheric emissions are mostly generated by steam production from boilers and incinerators for the dry process. SO2, NOx, CO2, CO, HCl, dust, VOC, and odor were common. In the EU-BREF (European union BAT reference documents) BAT for wastewater have taken up a relatively large proportion. Items of water pollutants in wastewater were common in COD, BOD, N, P, SS, and however EU-BREF had different pollutants such as AOX and salt compared to K-BREF. In order to improve the quality of the K-BREF, it is necessary to devise basic data research method and data acqusitiom method. Consideration should be given to additional environmental management techniques that reflect the emissions characteristics of the corrugated cardboard manufacturing process. In addition, further research is needed to develop methodologies for selecting BATs considering environmental and economic feasibility.

Spermiogenesis in the Korean Daubenton's Bat(Myotis daubentonii ussuriensis) (한국산 물윗수염박쥐(Myotis daubentonii ussuriensis)의 정자변태)

  • 손성원
    • Development and Reproduction
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    • v.1 no.1
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    • pp.9-24
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    • 1997
  • To investigate the process of spermiogenesis of the Korean eastern Daubenton's bat, Myotis daubentonii ussuriensis, the testis obtained from mature male bats was studied by transmission electron microscope and were based on the variety and diagnostic characters of cell organells. The results obtained from the present study are as follows. According to the differentiation of the cell organells, the spermiogenesis of the Korean eastern Daubenton's bat, M. d. ussuriensis, was divided into Golg, cap, acrosome, maturation and spermiation phases. Besides, these Golgi, cap, acrosome, and maturation phase were subdivided into the steps of early and late phases repectively and matruation phase was subdivided into step of early, mid and late phases. Therfore, the spermiogenesisof M. d. ussuriensis has been divided into a total of 11 phases. The chromatin granules began to condense at the early cap phase, regularized at the acrosome phase, and a perfect nucleus of sperm was formed at the maturation phase. The chromatoid body was occurred in the upper cytoplasm of nucleus at the early Golgi phase, and it was accurred the posterior cytoplasm of the nucleus at the early maturatio phase. The formation of sperm tail began to be develop in the early golgi phase, and completed at the spermiation phase. The fiber structure of middle piece was consisted of nine outer doublets and two central singlet microtubules and Nos. 1, 5, 6 and 9 in the outer dense were larger than the others(2, 3, 4, 7, 8).

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Detection of Puumala and Hantaan Viruses among Bats in Korea by Nested RT-PCR

  • Lee, Yun-Tai;Yun, Bo-Kyoung;Yoon, Jeong-Joong
    • The Journal of Korean Society of Virology
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    • v.28 no.2
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    • pp.147-155
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    • 1998
  • Hantavirus is a genus of the Bunyaviridae family consisting following serotype groups: Hantaan, Seoul, Puumala, Prospect Hill, Thailand, Belgrade, Thotta palayam, Sin Nombre. Most of Hantavirus group have been associated with many clinically similar disease known collectively as hemorrhagic fever with renal syndrome (HFRS). Hantaan virus is the prototype of the genus hantavirus, originally isolated from Apodemus agrarius. Bat was found as a natural host for Hantaan virus in Lee's lab for the first time. Then, Hantaan-like virus was isolated Hantaan-like virus from bat. To identify hantaviruses that are present in Korea among bats, bats were collected from Jeong-Sun, Won-Joo, Chung-Ju and Hwa-Cheon area, RNA was isolated from lung and serum. RT-PCR was performed with a universal primer from M segment. Nested RT-PCR was carried out to differentiate Hantaan, Seoul and Puumala virus using serotype specific primers. As we expected, Hantaan viruses were detected in bats and Seoul virus was not detected. Interestingly, Puumala viruses were also detected in bats from Won-Ju, but not in other areas. Puumala virus is originally isolated from Clethrinomys glareolus, and cause light HFRS. Recently, Paradoxomis webbiana, a wild bird turn out to be a reservoir for Puumala virus in Korea. These data indicate that bat is a new natural reservoir of Puumala virus.

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Presence of Rhodanese in the Cytosolic Fraction of the Fruit Bat (Eidolon helvum) Liver

  • Agboola, Femi Kayode;Okonji, Raphael Emuebie
    • BMB Reports
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    • v.37 no.3
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    • pp.275-281
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    • 2004
  • Rhodanese was isolated and purified from the cytosolic fraction of liver tissue homogenate of the fruit bat, Eidolon helvum, by using ammonium sulphate precipitation and CM-Sephadex C-50 ion exchange chromatography. The specific activity was increased 130-fold with a 53% recovery. The $K_m$ values for KCN and $Na_2S_2O_3$ as substrates were $13.5{\pm}2.2\;mM$ and $19.5{\pm}0.7\;mM$, respectively. The apparent molecular weight was estimated by gel filtration on a Sephadex G-100 column to be 36,000 Da. The optimal activity was found at a high pH (pH 9.0) and the temperature optimum was $35^{\circ}C$. An Arrhenius plot of the heat stability data consisted of two linear segments with a break occurring at $35^{\circ}C$. The apparent activation energy values from these slopes were 11.5 kcal/mol and 76.6 kcal/mol. Inhibition studies on the enzyme with a number of cations showed that $Mg^{2+}$, $Mn^{2+}$, $Ca^{2+}$, and $Co^{2+}$ did not affect the activity of the enzyme, but $Hg^{2+}$ and $Ba^{2+}$ inhibited the enzyme.

The BAT AGN Spectroscopic Survey: concept, status, and future perspectives

  • Oh, Kyuseok;Ueda, Yoshihiro;Koss, Michael;Ricci, Claudio;Schawinski, Kevin;Trakhtenbrot, Benny;Lamperti, Isabella
    • The Bulletin of The Korean Astronomical Society
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    • v.43 no.2
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    • pp.32.4-33
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    • 2018
  • We present the BAT AGN Spectroscopic Survey (BASS) which is an optical/NIR spectroscopic survey of the least biased sample of hard X-ray selected local AGN. For more than a thousand AGN that identified through Swift-BAT hard X-ray all-sky survey, we are conducting dedicated spectroscopic observing runs using world-class telescopes such as ESO-VLT, Magellan, and Palomar. The goal of the project is measuring black hole mass, investigating supermassive blackhole growth and its structure, and providing a baseline for future X-ray missions that will perform deeper observations of more distant AGN. In this presentation, we briefly introduce the concept of the project, past and the current status, and future work.

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HI gas properties of BAT-BASS AGN host galaxies

  • Kim, Jeein;Chung, Aeree;Baek, Junhyun;Oh, Kyuseok;Wong, O. Ivy;Koss, Michael J.
    • The Bulletin of The Korean Astronomical Society
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    • v.46 no.2
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    • pp.69.1-69.1
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    • 2021
  • We present preliminary results of the VLA archival HI data of local AGN hosts. The sample consists of the galaxies selected from the Swift-BAT hard X-ray survey. The main goal is to probe the gas environment of the sample in order to verify the role of gas accretion as one of the major AGN triggering mechanisms. HI, as a mostly diffuse and extended gas component in many galaxies, is a sensitive tracer to explore the impact of the surroundings on galaxies. In this work, we therefore probe the HI imaging data of a subsample of BAT-BASS AGN hosts, starting with the cases for which relatively high HI fluxes have been reported from the past single-dish observations. Based on their resolved HI properties, we will discuss the possibility of gas accretion and its role in powering AGNs in these examples.

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Effects of High Fat Diet on Serum Leptin and Insulin Level and Brown Adipose Tissue UCP 1 Expression in Rats (흰쥐에서 고지방식이가 혈중 렙틴 및 인슐린과 갈색지방조직의 UCP 1 발현에 미치는 영향)

  • 홍경희;강순아;김소혜;조여원
    • Journal of Nutrition and Health
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    • v.34 no.8
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    • pp.865-871
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    • 2001
  • The adipose tissue hormone leptin has been proposed to be involved in the regulation of flood intake and energy expenditure via thermogenesis by uncoupling protein(UCP) in brown adipose tissue(BAT). The objective of the study was to examine the effects of high fat diet on the serum leptin levels, BAT UCPl expression and the body fat mass in rats after weaning. During experimental period of 12 weeks, 4 male Sprague-Dawley rats were killed for the baseline experiment at 4 weeks of age while the remaining rats were fed the two different diets: the control diet AIN-76A(n = 20), high fat(beef tallow) diet(n = 20) ad libitum, which provided 11.7% or 40% of calories as fat, respectively. At 16 weeks of age, the increase in the food efficiency ratio(FER) was related to fat mass in rats on high fat diet. Serum leptin level was increased by age and dietary high fat. There was no difference in serum insulin level between groups until 10 weeks of age, but rats fed high fat diet for 12 weeks showed hyperinsulinemia. The amount of body fat pads was increased significantly in high fat group compared to normal diet group. Visceral fat mass affected acutely by high fat diet, as a result, it was higher in rats fed high fat diet for 2 weeks than normal diet. At 16 weeks of age, BAT and visceral fat mass were significantly high in high fat group. Also, the serum leptin levels reflected the amount of body fat mass. BAT UCPI mRNA expression increased with age and dietary high fat. This study demonstrates that dietary high fat increased serum leptin levels, BAT UCPI expression and body fat mass. Futhermore, in rats fed high fat diets, the increases in leptin and UCPI expression counteracts only in part the excess adiposity and obesity.

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A Dynamic Offset and Delay Differential Assembly Method for OBS Network

  • Sui Zhicheng;Xiao Shilin;Zeng Qingji
    • Journal of Communications and Networks
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    • v.8 no.2
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    • pp.234-240
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    • 2006
  • We study the dynamic burst assembly based on traffic prediction and offset and delay differentiation in optical burst switching network. To improve existing burst assembly mechanism and build an adaptive flexible optical burst switching network, an approach called quality of service (QoS) based adaptive dynamic assembly (QADA) is proposed in this paper. QADA method takes into account current arrival traffic in prediction time adequately and performs adaptive dynamic assembly in limited burst assembly time (BAT) range. By the simulation of burst length error, the QADA method is proved better than the existing method and can achieve the small enough predictive error for real scenarios. Then the different dynamic ranges of BAT for four traffic classes are introduced to make delay differentiation. According to the limitation of BAT range, the burst assembly is classified into one-dimension limit and two-dimension limit. We draw a comparison between one-dimension and two-dimension limit with different prediction time under QoS based offset time and find that the one-dimensional approach offers better network performance, while the two-dimensional approach provides strict inter-class differentiation. Furthermore, the final simulation results in our network condition show that QADA can execute adaptive flexible burst assembly with dynamic BAT and achieve a latency reduction, delay fairness, and offset time QoS guarantee for different traffic classes.