• Title/Summary/Keyword: BAG-1

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Correlation between Clinicopathology and Expression of HSP70, BAG1 and Raf-1 in Human Diffuse Type Gastric Carcinoma (미만형 위암에서 임상병리학적 인자와 Hsp70, BAG1과 Raf-1 발현간의 상관성)

  • Jung, Sang Bong;Lee, Hyoun Wook;Chung, Kyung Tae
    • Journal of Life Science
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    • v.26 no.1
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    • pp.101-108
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    • 2016
  • The aim of this study was to evaluate the relationships between the expression of Heat shock protein70 (HSP70), Raf-1 and Bcl-2-associated athanogene-1 (BAG1) protein in diffuse type gastric carcinoma and examine association of HSP70, Raf-1 and BAG1 expression with various clinic-pathological factors and survival. Heat shock protein70 is induced in the cells in response to various stress conditions, including carcinogens. Overexpression of heat shock protein 70 has been observed in many types of cancer. The proto-oncoprotein Raf is pivotal for mitogen-activated protein kinase (MAPK) signaling, and its aberrant activation has been implicated in multiple human cancers. Overexpression of BAG1 protein has been documented in some type of human cancer. BAG1 has been reported to interact with protein involved with a variety of signal pathway, and regulation of cell differentiation, survival and apoptosis. These interaction partners include HSP70 and Raf-1. The percentage of tumors exhibiting HSP70 positivity was significantly in cases of positive lymph node metastasis (64.9%) compared to cases without lymph node metastasis (35.1%, p=0.007). HS70 expression was correlated with pathological N-stage (p=0.006). Expression of BAG1 was detected in the majority of diffuse type gastric carcinoma tissues (71.7%), especially in younger patients (80% vs 52.6%, p=0.035). Furthermore BAG1 expression was correlated with tumor size (p=0.020). Raf-1 expression was found to be significantly associated with tumor size (p=0.005). The result indicate that HSP70 was significantly correlated the progression of diffuse type gastric cancer. Expression of BAG1 and Raf-1 may be used as diagnostic markers for gastric carcinoma.

A Study on Bag Purchasing Behaviors and Design Preferences - Focusing on Comparative analysis by Sex and Age group - (가방 구매행동과 디자인 선호도 연구 - 성별과 연령집단에 따른 비교분석을 중심으로 -)

  • Mi-sook Lee
    • Journal of the Korea Fashion and Costume Design Association
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    • v.25 no.3
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    • pp.1-16
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    • 2023
  • The purposes of this study were to investigate bag purchasing behaviors and design preferences of male and female adult consumers, and to find the differences depending on sex and age variable. A survey was conducted on 400 male and female adults from 20s to 50s. The questionnaire consisted of bag purchase behaviors, bag design preferences, and the subjects' demographic characteristics. The data were analyzed by Cronbach's α, factor analysis, x2 test and t-test using SPSS. The results were as follows. First, as bag selection criteria, four factors (practicality, symbolism, aesthetics, and economics) were derived, and adult consumers considered economics as the most important among the factors. As for purchasing information sources, three factors (media, human resources, and store) were derived, and adult consumers considered human resources and store information sources more important than media. The main motive for purchasing bags was age and damage of the owned products, and Internet shopping malls were the most common purchasing place. The average annual cost of purchasing bags was 100,000 to 300,000 won, and the frequency of purchase was about once a year. Second, as bag preference images, four factors (individual, romantic, active, and classic image) were derived, and adult consumers preferred classic images the most. The shoulder bag was the most preferred as the bag shape, and black was the most preferred bag color. For the material, natural leather was the most preferred, and for the size, medium size was the most preferred. Third, bag purchasing behaviors and design preferences showed many significant differences according to the sex and age of the consumers. Therefore, the results of this study suggests that bag companies need to establish product development and marketing strategies in consideration of differences according to the sex and age group of adult consumers.

Measurements of Trimethylamine (TMA) in air by Tedlar bag sampling and SPME analysis (환경대기 중 Trimethylamine (TMA)의 측정: Tedlar bag 방식의 채취와 SPME 분석법의 특성 연구)

  • Kim, K.H.;Hyum, S.H.;Im, M.S.
    • Analytical Science and Technology
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    • v.19 no.1
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    • pp.96-102
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    • 2006
  • Trimethylamine (TMA) is one of the difficult odorous compounds for the collection and analysis. Although sulfuric acid absorption and/or sulfuric acid impregnated filter method are commonly recommended for its sampling, these methods also suffer from difficulties involved in sample treatment and operational procedures. Hence, as an ancillary approach to measure TMA, we investigated the combination of bag sampling and SPME analysis for TMA measurements. For the purpose of our study, we investigated the following three subjects: 1) temporal variability of standard storage, 2) bag loss effect of TMS, and 3) TMA loss due to repetitive analysis of an identical bag sample. According to our storage test up to 7 or 20 dyas, TMA loss were found to occur up to 40 to 50% within relatively short period of up to 48 hrs depending on its concentration ranges. When the tests were made for bag loss by transferring TMA standards across different size bags, we were able to find that the extent of bag loss are not significant with 5 to 20% loss rate. Finally, the TMA sorptive loss via its exposure to SPME fiber was generally estimated to run from 2 to 3%.

Storage Period of Milled Rice by Packaging Materials and Storage Temperature (온도와 포장재에 따른 백미의 저장가능기간)

  • Choi Yoon-Hee;Choung Jin-Il;Cheong Young-Keun;Kim Young-Doo;Ha Ki-Yong;Ko Jae-Kwon;Kim Chung-Kon
    • Food Science and Preservation
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    • v.12 no.4
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    • pp.310-316
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    • 2005
  • This study was carried out to investigate the quality characteristics by packaging materials and storage temperature to predict safe storage period for milled rice. Mechanical taste value and whiteness of milled rices stored at room temperature were severely decreased than those of the stored at low temperature, but fat acidity and b value of those at room temperature was rapidly increased than those of stored at low temperature. Milled rice packed in LDPE film bag were smelled stale flavor after 4 months storage at room temperature, Hojinbyeo was not produced flour in the rice grain surface but Dongjinbyeo was showed production of flour. pH of milled rice of Dongjinbyeo and Hojinbyeo packed in LDPE film bag were the lowest showing 5.3 and 5.6, respectively after 6 months at mom temperature. Safe storage period of Dongjinbyeo and Hojinbyeo packed in craft paper bag were 1 month at room temperature, those of packed in LDPE film bag were 2 months. At low temperature safe storage period of Dongjinbyeo and Hojinbyeo packed in craft paper bag were 2 months, those of packed in LDPE film bag were 5 and 4 months, respectively.

Studies on the Behaviour of Fish Schools in the Main-Net of a Large Scale Set-Net Using a Scanning Sonar ( III ) - The Behaviour of Anchovy Engraulis Japonica Sonar-III (소나 관찰에 의한 대형정치망내 어군행동의 연구 ( III ) - 원통내 멸치어군의 행동과 원통의 기능)

  • Kim, Mung-Kwan;Inoue, Yoshihiro;Park, Jeong-Sik
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.32 no.3
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    • pp.217-222
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    • 1996
  • The moving behaviour of anchovy schools(There were small schools of sardine and round-herring in this anchovy schools} in the bag - net of a large scale set - net was investigated using a scanning sonar, in the Kishihata set - net fishing ground located in Nanao city Ishigawa prefecture, Japan from Dec. 1st to Dec. 4th, 1992. The results obtained are summarized as follows ; 1. Moving behaviour of fish schools between two bag - nets was more in the daytime than in the nighttime. 2. The rate of entering fish schools from the first bag -- net to the second bag - net were 78% when the fish school in the second bag -- net existed. The result suggest that fish school existence in the second bag - net affected the rate of entering fish schools from the first bag - net to the second- bag - net. However, the time of stay of fish school that entered the second bag -- net was very short when the fish school in the second bag - net existed densely. The result suggest that a high fish density in the second bag - net might enlarge the escape rate 3. The majority of fish schools moved to the center and off shore side of the bag - net when fish schools entered the bag - net.

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Study on the Anchovy Boat Seine-IV An Experiment to Mechanize the Hauling Operation of Bag Net (기선권현 강의 연구 -IV)

  • 이병기
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.15 no.2
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    • pp.95-100
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    • 1979
  • In fishing with the anchovy boat seine, it is required to haul up the bag net without injuring anchovy body. Not to injure anchovy body, the bag net is operated with 30 to 34 crews in the traditional method. With a view point of decreasing crews, the authors tried to operate the bag net with side drum winch and derrick boom. Side drum winch was installed beside the engine casing and it was operated by the main engine through the belt, pulley and bevel gear. The derrick boom, 7 meters long, was installed above the working deck which is located in the stern of the common boat seiner. Three single blocks are attached to the boom, each 2 meters apart from the top. A hook was attached to the free end of the block line for hooking up the bolch line which attached inside the bag net especially prepared for the purpose. The hauling end of the block line was induced to the side drum winch for hauling up the bag net. By using this mechanism, the bag net was hauled up with peeling the bag net just like in the traditional method. So the following results are found. (1) No injury of anchovy body was found in the process of hauling up. (2) The bag net can be operated by mere 14 crews. (3) Duration, spent in hauling up the bag net, was almost the same when the catch are a little amount, and less duration was needed by the experimented method than the traditional one when the catch are a large amount. the bag net. By using this mechanism, the bag net was hauled up with peeling the bag net just like in the traditional method. So the following results are found. (1) No injury of anchovy body was found in the process of hauling up. (2) The bag net can be operated by mere 14 crews. (3) Duration, spent in hauling up the bag net, was almost the same when the catch are a little amount, and less duration was needed by the experimented method than the traditional one when the catch are a large amount.

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Comparison for Loss Rate of Low Concentration Nitrous Oxide in Tedlar Bag and Aluminium-Polyester Bag (테들러백과 알루미늄-폴리에스터백에 보관된 저농도 아산화질소의 유실율 비교)

  • Lee, Woo Chan;Park, Sung Bin;Ko, Young Hwan;Hyun, Seung Min;Yoon, Kyoon Duk
    • Journal of Climate Change Research
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    • v.8 no.1
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    • pp.31-39
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    • 2017
  • The emission quantity of nitrous oxide is second largest among non-$CO_2$ greenhouse gas in Korea. In this study, we investigated loss rate of nitrous oxide which was filled in PVF and Al-PE bag as time goes on. Concentrations of tested samples were about 25 ppmv, 50 ppmv, 75 ppmv prepared by standard reference gas. In case of all experiments, loss rate of PVF bag was higher than Al-PE bag. After 18 days, loss rate of PVF bag was from 29.7% to 38.6% while Al-PE bag was from 21.7% to 23.7%. Especially the differential growed bigger when initial concentration of $N_2O$ in PVF bag was lower. And we also studied the effect of cock opening/closing procedures on loss rate. Prepared samples in experimental group were analyzed several times for 20 days and samples in control group were analysed only 1 time after 20 days. The experimental results showed that cock opening/closing procedures appeared to have little impact on loss rate.

Silk Reelability of the Cocoon Stored in a Pelyethylene Bag (Polyethylene대 저견이 조사에 미치는 영향)

  • 최병희;송기언
    • Journal of Sericultural and Entomological Science
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    • v.6
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    • pp.31-33
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    • 1966
  • This work has been carried out for many months to check whether polyethylene bag cocoon storging method bring better reeling result against the normal cotton bag storing method. The obtained results were as followings. 1. The pupa killed cocoons could be stored on the ground in case of packing in polyethylene-bag until the secondary dry process. 2. The raw silk percentage of cocoon stored in polyethylene bag, increased 0.5% than the cotton bag storing method, not because of its reelability, but because of the better yield of cocoon bave. 3. Musty cocoon was not shown during the polyethylene hag storage, but the cocoons were attacked by rats as usually. 4. Polyethylene bag storing method invited more insects attack than the normal method, but the attack was able to cease by enclosing two naphthalene tablets in each bag.

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Characteristics of Cyclone-Bag Filter with Bottom Inlet (하부유입식 원심 여과집진장치의 특성)

  • Yoa, Seok-Jun
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.4
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    • pp.639-650
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    • 2000
  • The main object of this study was to investigate experimentally the characteristics of cyclone-bag filter with bottom inlet to decrease the high pressure drop which was one of main problems of fabric bag filter. The experiment was executed for the analysis of collection efficiency and pressure drop(specially, pressure drop of fabric filter) characteristics of the cyclone-bag filter in comparison with those of general fabric bag filter with various experimental parameters such as the inlet velocity, dust loading and variation of vortex region, etc. In the results, the tangential inlet type showed higher collection efficiency for submicron particles below $1{\mu}m$ in diameter than of center inlet, and over 99% for overall collection efficiency. For the inlet particle concentration $100mg/m^3$, pressure drop reduction ratios were shown as 15~38% with the inlet velocity in case of large bag, while 30~48% for small bag due to the increase of vortex region.

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Changes of relative impulse of foot on carrying 5 types of schoolbag during level walking (가방 휴대 방법에 따른 보행 시 발의 비례추진력 변화)

  • Pack, Soo-Jin;Kim, Min-Hee;Kim, Jin-Sang
    • The Journal of Korean Physical Therapy
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    • v.21 no.3
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    • pp.61-68
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    • 2009
  • Purpose: The purpose of this study was to analyze the changes of the relative impulse of the foot when carrying 5 types of schoolbag during level walking. Methods: Forty-four normal subjects were divided into 5 groups according to the method of carrying a bag: carrying no bag (condition 1), a backpack (condition 2), a shoulder bag (condition 3), a cross bag (condition 4) and a one-hand bag (condition 5). To evaluate the partial relative impulse, 7 areas were measured on the sole of a foot: the hallux, toe, 1st metatarsal head (Met1) and the 2nd & 3rd metatarsal heads (Met2/3), the 4th & 5th metatarsal heads (Met4/5), mid foot and heel. Repeated one-way analysis of variance (ANOVA) and independent t-tests were used to analyze the statistical data. Results: In the right foot, the relative impulses in every areas revealed no significant difference (p>0.05), however, the relative impulses at Met1, Met2/3, Met4/5 and heel were significantly different between the different conditions (p<0.05). There were significant differences on comparing the relative impulse between left and right foot within one condition, the mid foot in condition 2, as well as the hallux and Met1 in condition 3 (p<0.05). In condition 4, the toe, Met1, Met4/5 and mid foot were significantly different (p<0.05). The values at the hallux, toe and Met1 in condition 5 also were significantly different (p<0.05). Conclusion: These findings showed that the symmetrical relative impulse of the foot was present in the case of carrying a backpack, but there was an extra load on specific regions and asymmetrical relative impulses in the case of carrying a shoulder bag, a across bag and a one-hand bag. (ED note: this abstract is not clear. You need to work on it.)

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