• Title/Summary/Keyword: B7-H4

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Synthesis of Novel 1,2-Diazepino[3,4-b] quinoxalines and pyridazino[3,4-b] quinoxalines (새로운 1,2-다이아제피노 [3,4-b]퀴녹살린류와 피리다지노 [3,4-b] 퀴녹살린류의 합성)

  • Kim, Ho-Sik;Lee, Seong-Uk;Jeong, Geuk;Lee, Man-Kil;Kurasawa, Yoshihisa
    • YAKHAK HOEJI
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    • v.44 no.4
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    • pp.325-333
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    • 2000
  • The 1,3-dipolar cycloaddition reaction of the quinoxaline 4-oxides 2 with 2-chloroacrylonitrile gave the 2,3-dihydro-1H-1,2-diazepino[3,4-b]quinoxalines 3, which were converted into the 2,3,4,6-tetrahydro-1H-1,2-diazepino[3,4-b]quinoxalines 5-7. The reaction of compounds 3 with selenium dioxide in acetic acid/water resulted in ring transformation to give the 1,4-dihydro-4-oxopyridazino[3,4-b]quinoxalines 8.

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The Crystal and Molecular Structure of Ethylenediammonium bis (P-Methylbenzenesulfonate) Monohydrate (에티렌디암모늄 비스(파라-메틸벤젠슬폰네이트) 수화물의 결정 및 분자구조)

  • Choong Tai Ahn;Eul-San Kim
    • Journal of the Korean Chemical Society
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    • v.29 no.4
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    • pp.335-340
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    • 1985
  • The crystal structure of ethylenediammonium bis (p-methylbenzenesulfonate) monohydrate, $C_2H_{10}N_{22}^{+2}{\cdot}(C_7O_3H_7S^-){\cdot}H_2O$ has been determined by X-ray diffraction techniques. The space group is P21, in 2 unit cell with a = 12.649 (2) ${\AA}$, b = 7.727 (1) ${\AA}$, c = 11.295 (2) ${\AA}$, ${\beta}$ =111.8(1)$^{\circ}$, and z = 2. The structure was solved by direct methods and refined to R = 0.060 for 1134 reflections measured with Mo-K${\alpha}$ radiation. Two p-methylbenzenesulfonates, fragment A and B, from a pair through the hydrogen bonds to the ethylenediammonium ion. The sulfonate group in the fragment B are disordered. There are six unique hydrogen bonds, of which four are between the ethylenediammonium ion and the sulfonate groups and remaining two involve the water molecule.

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The Characteristics of Growth of Brochothrix thermosphacta on Packaged Beef (포장우육에서 Brochothrix thermosphacta의 생육특성에 관한 연구)

  • Shin, Heuyn-Kil;Kim, Haeng-Ha;Chin, Koo-Bok
    • Korean Journal of Food Science and Technology
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    • v.20 no.1
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    • pp.85-89
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    • 1988
  • This work was carried out to get the basic data about packaged meat by investigating the characteristics of growth of B. thermosphacta. For this purpose. B. thermosphacta and Lactic acid bacteria were isolated from the vacuum-packaged beef and the effect of various conditions such as pH of beef, packaging method, and Lactobacilli on the growth of B. thermosphacta was investigated. In aerobic packaged beef, the pH did not affected the growth of the B. thermosphacta, while it did affected critically in vacuum packaged beef. The lowest pH for the growth of B. thermosphacta in aerobic-packaged beef was 5.3-5.4 and 5.4-5.5 in vacuum-packaged beef. The growth of B. thermosphacta was completely stopped when the beef with pH 5.7-6.0 was packaged in 100% $CO_2$, but it was not affected significantly when the beef was packaged in a mixture of $CO_2$(20%) and $N_2$(80% ). The inhibitory effect of lactic acid bacteria on the growth of B. thermosphacta was observed faintly in aerobic-packaged beef, but in vacuum-packaged beef, the lower the pH , the more significant its inhibitory effect. The growth of B. thermosphacta was almost stopped in a beef with pH 5.5-5.6.

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Bactericidal Effects of Food-borne Bacteria using Chlorine Dioxide and Electrolyzed Water (이산화염소수와 전해수를 이용한 식중독균의 살균효과)

  • Lee, Hye-Rin;Kim, Su-Jin;Bang, Woo-Suk
    • Journal of Food Hygiene and Safety
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    • v.37 no.4
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    • pp.232-237
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    • 2022
  • The present study investigated the bactericidal effects of chlorine dioxide (CD) and electrolyzed water (EW) on pathogenic bacteria, such as Bacillus cereus, Staphylococcus aureus, Salmonella Typhimurium, and Escherichia coli O157:H7, by treatment them with CD and EW, respectively, for 0, 2, 4, 6, 8, and 10 min. Additionally, the sensitivities of Gram-positive (B. cereus and S. aureus) and Gram-negative (S. Typhimurium and E. coli O157:H7) to CD and EW were compared, respectively. In CD, the D-values for B. cereus, S. aureus, S. Typhimurium, and E. coli O157:H7 were 1.85±0.64, 2.06±0.85, 2.26±0.89, and 2.59±0.40 min, respectively. In EW, the D-values for B. cereus, S. aureus, S. Typhimurium, and E. coli O157:H7 were 2.13±0.32, 1.64±0.64, 1.71±0.32, and 1.86±0.36 min, respectively. All strains decreased consistently for 10 min in both CD and EW. However, the D-values of each bacterial species did not differ significantly between CD and EW (P>0.05). When comparing the bactericidal effect of CD and EW, no difference in D-value was observed, even though the pH and available chlorine concentration of CD were significantly lower than those of EW. These data could be used for the application of CD and EW in the food industry, considering characteristics such as the selection of optimal disinfectants, determination of optimal concentrations, and sensitivity to disinfection targets.

4H-SiC MESFET Large Signal Modeling using Modified Materka Model (Modified Materka Model를 이용한 4H-SiC MESFET 대신호 모델링)

  • 이수웅;송남진;범진욱
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.12 no.6
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    • pp.890-898
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    • 2001
  • 4H-SiC(silicon carbide) MESFET large signal model was studied using modified Materka-Kacprzak large signal MESFET model. 4H-SiC MESFET device simulation have been conducted by Silvaco\`s 2D device simulator, ATLAS. The result is modeled using modified Materka large signal model. simulation and modeling results are -8 V pinch off voltage, under V$\_$GS/=0 V, V$\_$DS/=25 V conditions, I$\_$DSS/=270 mA/mm, G$\_$m/=52.8 ms/mm were obtained. Through the power simulation 2 GHz, at the bias of V$\_$GS/-4 V md V$\_$DS/=25 V, 10 dB Gain, 34 dBm (1dB compression point)output porter, 7.6 W/mm power density, 37% PAE(power added efficiency) were obtained.7.6 W/mm power density, 37% PAE(power added efficiency) were obtained.d.

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Motion Compensation and B Picture

  • 전병문
    • Broadcasting and Media Magazine
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    • v.7 no.3
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    • pp.19-23
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    • 2002
  • 본 장에서는 H.26L 비디오 코덱에 적용되는 움직임 보상 기법(motion compensation) 및 B 픽쳐(Bi-predictive picture) 에 대해 다루기로 한다. 먼저 H.26L 비디오 코덱이 H.263 또는 MPEG-4 Part 2와 같은 종래 비디오 코덱들과 움직임 보상 관점에서 다른 점을 살펴보면, 복수개의 레퍼런스 픽쳐(multiple reference picture) 로부터 움직임 추정 (motion estimation) 밀 움직임 보상을 수행하고, 16x16 매크로 블록 크기부터 16x8, 8x16, 8x8블록 크기에서 매크로 블록 모드 타입이 결정되고 8x8 모드는 다시 8x4, 4x8, 4x4 단위에서 서브 모드 타입이 결정된다. 따라서 한 개의 매크로블록은 최대 16개의 모션벡터를 깆을 수 있다. 또한 복수개의 레퍼런스 픽쳐와 다양한 블록 타입을 적용함에 따라 모션벡터 예측(PMV: prediction of motion vector) 은 현재 블록과 이웃하는 블록들 사이의 레퍼런스 픽쳐 인덱스 비교 및 현재 블록 타입이 16x8또는 8x16 일 때 방향성 예측을 허용하는 새로운 기법들이 소개되어 있다. 그리고 코딩 효율을 높이기 위한 방법으로서 1/4 pel 단위의 움직임 보상을 하여 블록의 예측 정확도를 높이도록 하고 있다. 한편, H.26L에서의 B 픽쳐는 종래 비디오 코덱에 비해 확장된 정의를 갖고 있다. 예를 들어, 종래의 비디오 코덱에서는 B 픽쳐가 시간 스케일러빌러티(temporal scalability)에 사용됨에 따라 레퍼런스 픽쳐로서 사용될 수 없지만, H.26L은 B 픽쳐가 레퍼런스 픽쳐로서 사용되는 것을 허용하고 있다. 또한 종래의 B 픽쳐가 양방향에서 움직임 보상을 한 것과 달리 H.26L은 동일 방향에 존재하는 두개의 레퍼런스 픽쳐에서도 움직임 보상을 허용한다.

Crystal Structure of 1-Cyclopropyl-7-(2,7-diazabicyclo[3.3.0]oct-4-en-7-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (HCI salt) (1-Cyclopropyl-7-(2,7-diazabicyclo[3.3.0]oct-4-en-7-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 염산염의 결정구조)

  • 김문집;신준철
    • Korean Journal of Crystallography
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    • v.6 no.2
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    • pp.103-110
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    • 1995
  • The crystal structure of 1-Cyclopropyl-7-(2,7-diazabicyclo[3.3.0]oct-4-en-7-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (HCI salt) has been determined from single crystal x-ray diffraction study ; C20H21N3O4FCl, Monoclinic, C2/c, a=28.349(2)Å, b=11.941(2)Å, c=12.806(2)Å, β=96.428(9)°, V=4307.8Å3, T=296(2)K, Z=8, CuKα(λ=1.5418Å). The molecular structure was solved by direct method and refined by full-matrix least squares to a final R=4.96% for 2258 unique observed F0>4σ(F0) reflections and 293 parameters. The conformation of the molecule is stabilized by an intramolecular O(28)-H(28)…O(25) [2.517(4)Å, 156.7(447)°] hydrogen bond. Intermoleculars distances correspond to van der Waals contacts.

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Melanoidin decolorization by immobilized cells of Aspergillus awamori, B-2 (Aspergillus awamori B-2의 균사체 고정화 의한 Melanoidin 탈색)

  • Ryu, Beung-Ho;Kim, Hye-Sung;Ha, Mi-Suk;Jung, Jong-Sun;Bin, Jae-Hun;Lee, Yung-Sook;Chung, Soo-Ja
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.18 no.1
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    • pp.47-52
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    • 1989
  • Aspergillus awamori, B-2 which has a high ability to decolorize melanoidin was selected among various fungi. Aspergillus awamori, B-2 showed the highest decolorization activity when it was cultivated in a melanoidin medium containing 3.0% glucose, 0.5% yeast extract, 0.1 % $KH_2PO_4\;and\;0.05%\;MgSO_4{\cdot}7H_2O$ at an initial pH 7.0 at $37^{\circ}C$ for 5 days. Mycelia immobilized system with. Ca-alginate was more effective on melanoidin decolorization activity showed approximately 70% in 10 days under the optimal conditions. Continuous decolorization of melanoidin using, reuse of immobilized mycelia showed an almost constant decolorization of abort 60-70% for 15 days.

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Design of Fractal Structure Wideband Antenna for 4G IMT-Advanced AccessPoint Applications (4세대 이동통신 Accesspoint용 Fractal구조 광대역 안테나 설계)

  • Kim, Dong-Hwan;Kim, Gab-Gi
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.14 no.1
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    • pp.195-201
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    • 2014
  • In this paper, an AccessPoint compact microstrip patch antenna was designed by using L-shaped feeding structure of a Fractal Structure and the compact antenna can be obtained by the rare formed presence of the resonance flow which is called "Crossed-Diagonal". CST's MicroWave5.0 was used for the design. As the operating characteristics of the patch antenna, it showed the characteristic of 1031 [MHz] or 29.4% in the range of 3.202 [GHz] ~ 4.233 [GHz] when an input return loss is less -10 [dB] and VSWR 2:1, also as it is in this paper, we got simulation results such as, gains of the E-plane and H-plane are 8.7 [dBi] and 8.6 [dBi] for this is the single patch, and 3 [dB] beamwidth is $43.9^{\circ}$ at E-plane and $78.7^{\circ}$ at H-plane.

Behavior of Burkholderia thailandensis (Burkholderia pseudomallei surrogate) in Acidified Conditions by Organic Acids Used in Ready-to-Eat Meat Formulations under Different Water Activities

  • Yoon, Yo-Han
    • Food Science of Animal Resources
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    • v.30 no.6
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    • pp.946-950
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    • 2010
  • This study evaluated the antimicrobial effects of meat processing-related organic acids on Burkholderia thailandensis (Burkholderia pseudomallei surrogate) with different water activities. B. thailandensis KACC12027 (4 log CFU/mL) was inoculated in microwell plates containing tryptic soy broth pH-adjusted to 4, 5, 6, and 7 with ascorbic acid, citric acid, and lactic acid and with water activities adjusted to 0.94, 0.96, 0.98, and 1.0 with NaCl, followed by incubation at $35^{\circ}C$ for 30 h. The optical density (OD) of the samples was measured at 0, 3, 6, 12, 24, and 30 h at 595 nm to estimate the growth of B. thailandensis. Growth of B. thailandensis was observed only at water activity of 1.0. In general, more bacterial growth (p<0.05) was observed at pH 6 than at pH 7, and the antimicrobial effects of the organic acids on B. thailandensis were in the following order: Ascorbic acid > lactic acid > citric acid after incubation at $35^{\circ}C$ for 30 h. These results indicate that organic acids in meat processing-related formulations should be useful in decreasing the risk related to an emerging high risk agent (B. pseudomallei).