• Title/Summary/Keyword: B-cell lympoma of MALT

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Dural Marginal Zone Lymphoma Confused with Meningioma en Plaque

  • Kim, Min-Young;Kim, Seong-Min;Chung, Seung-Young;Park, Moon-Sun
    • Journal of Korean Neurosurgical Society
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    • v.42 no.3
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    • pp.220-223
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    • 2007
  • We report a case of dural marginal zone lymphoma which showed the usual radiological findings resembling meningioma. A 59-year-old woman presented with headache. Initial computed tomography and magnetic resonance images showed a frontal convexity meningioma. The patient underwent a craniotomy and subtotal (simpson grade II) resection of tumor was done. Pathological examination confirmed an extranodal marginal zone B-cell lymphoma of Mucosa-Associated Lymphoid Tissue (MALT). The lesion was composed of a lymphoid mass with irregularly shaped follicles surrounded by many monomorphic small lymphocytes and a stained marginal zone for B-cell markers CD20 and CD29a. The natural history of primary CNS lymphoma and MALT type lymphoma are different. B-cell MALT lymphoma can mimic meningioma in its radiological features. Accordingly, MALT lymphoma of the CNS must be considered in the differential diagnosis of meningioma.