• Asian Journal of Atmospheric Environment
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• v.12 no.3
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• pp.232-243
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• 2018

The construction, development and maintenance of an economically, environmentally and socially sustainable campus involves the integration of measuring tools and technical information that invites and encourages the community to know the actual state to generate positive actions for reducing the negative impacts over the local environment. At the Universidad Nacional de Colombia - Campus $Bogot{\acute{a}}$, a public area with daily traffic of more than 25000 people, the Environmental Management Bureau has committed with the monitoring of the noise pollution and air quality, as support to the campaigns aiming to reduce the pollutant emissions associated to the student's activities and campus operation. The target of this study is based in the implementation of mobile air quality and sonometry monitoring equipment, the mapping of the actual air quality and noise pollution inside the university campus as a novel methodology for a sub-area inside a megacity. This results and mapping are proposed as planning tool for the institution administrative sections. A mobile Kunak$^{(R)}$ Air & OPC air monitoring station with the capability to measure particulate matter $PM_{10}$, $PM_{2.5}$, Ozone ($O_3$), Sulfur Oxide ($SO_2$), Carbon Monoxide (CO) and Nitrogen Oxide ($NO_2$) as well as Temperature, Relative Humidity and Latitude and Longitude coordinates for the data georeferenciation; and a sonometer Cirrus$^{(R)}$ 162B Class 2 were used to perform the measurements. The measurements took place in conditions of academic activity and without it, with the aim of identify the impacts generated by the campus operation. Using the free code geographical information software QGIS$^{(R)}$ 2.18, the maps of each variable measured were developed, and the impacts generated by the operation of the campus were identified qualitative and quantitively. For the measured variables, an increase of around 21% for the $L_{Aeq}$ noise level and around 80% to 90% for air pollution were detected during the operation period.

• The Korean Journal of Physiology and Pharmacology
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• v.17 no.5
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• pp.455-461
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• 2013

Retinoids regulate not only various cell functions including proliferation and differentiation but also glucose and lipid metabolism. After we observed a marked up-regulation of cellular retinol-binding protein-I (CRBP-I) in the liver of hepatitis B virus x antigen (HBx)-transgenic (HBx Tg) mice which are prone to hepatocellular carcinoma (HCC) and fatty liver, we aimed to evaluate retinoid pathway, including genes for the retinoid physiology, CRBP-I protein expression, and retinoid levels, in the liver of HBx Tg mice. We also assessed the effect of chronic metformin treatment on HCC development in the mice. Many genes involved in hepatic retinoid physiology, including CRBP-I, were altered and the tissue levels of retinol and all-trans retinoic acid (ATRA) were elevated in the liver of HBx Tg mice compared to those of wild type (WT) control mice. CRBP-I protein expression in liver, but not in white adipose tissue, of HBx Tg mice was significantly elevated compared to WT control mice while CRBP-I protein expressions in the liver and WAT of high-fat fed obese and db/db mice were comparable to WT control mice. Chronic treatment of HBx Tg mice with metformin did not affect the incidence of HCC, but slightly increased hepatic CRBP-I level. In conclusion, hepatic CRBP-I level was markedly up-regulated in HCC-prone HBx Tg mice and neither hepatic CRBP-I nor the development of HCC was suppressed by metformin treatment.

• Journal of Microbiology and Biotechnology
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• v.19 no.9
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• pp.1041-1050
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• 2009

Equine respiratory disease is a common cause of poor performance and training interruptions. The higher incidence rate of infectious upper respiratory disease (IURD) in thoroughbred racehorses at the Seoul Race Park coincided with the frequent stabling season, shorter stabling periods, and younger ages in this study. Incidence rates were also correlated with significantly lower proportions of cells expressing MHC class II-, CD2 antigen-, $CD4^+$- or $CD8^+$-T lymphocyte-, and B lymphocyte in IURD patients compared with healthy control groups in the summer and fall and in 2-and-3-year-old groups. The data suggested that movement and new environments may have resulted in immunosuppression and inappropriate responses to respiratory pathogens in IURD patients. The IURD incidence decreased with age, perhaps by the acquisition of immunity, and study results suggested that immunologic protection was associated with IURD, particularly in young thoroughbred racehorses. Streptococci isolates were identified in 11 of 72 IURD horses, and 3 of these isolates were identified as Streptococcus. equi subsp. equi. S. equi subsp. zooepidemicus was isolated from 2 of 23 IURD horses in the spring (8.7%), 5 of 23 in the summer (21.7%), and 1 of 6 in winter (16.7%). S. equi subsp. zooepidemicus (5%) was also identified in 3 of 61 isolates from clinically normal horses. Racetracks should implement anti-IURD protective measures by assessing the capacity of equine immunologic protection at the Park and by limiting the introduction of specific respiratory pathogens (such as S. equi subsp. equi) by preventing the access of infected but subclinical horses with a specified respiratory pathogen-free certification system prior to Park entry.

• Radiation Oncology Journal
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• v.32 no.1
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• pp.14-22
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• 2014

Purpose: To evaluate the safety and efficacy of transcatheter arterial chemoembolization (TACE) followed by radiotherapy (RT) in treatment-na$\ddot{i}$ve patients with locally advanced hepatocellular carcinoma (HCC). Materials and Methods: Eligibility criteria were as follows: newly diagnosed with HCC, the Barcelona Clinic Liver Cancer stage C, Child-Pugh class A or B, and no prior treatment for HCC. Patients with extrahepatic spread were excluded. A total of 59 patients were retrospectively enrolled. All patients were treated with TACE followed by RT. The time interval between TACE and RT was 2 weeks as per protocol. A median RT dose was 47.25 $Gy_{10}$ as the biologically effective dose using the ${\alpha}/{\beta}$ = 10 (range, 39 to 65.25 $Gy_{10}$). Results: At 1 month, complete response was obtained in 3 patients (5%), partial response in 27 patients (46%), stable disease in 13 patients (22%), and progressive disease in 16 patients (27%). The actuarial one- and two-year OS rates were 60.1% and 47.2%, respectively. The median OS was 17 months (95% confidence interval, 5.6 to 28.4 months). The median time to progression was 4 months (range, 1 to 35 months). Grade 3 or greater liver enzyme elevation occurred in only two patients (3%) after RT. Grade 3 gastroduodenal toxicity developed in two patients (3%). Conclusion: The combination treatment of TACE followed by RT with two-week interval was safe and it showed favorable outcomes in treatment-na$\ddot{i}$ve patients with locally advanced HCC. A prospective randomized trial is needed to validate these results.

• Journal of Digital Convergence
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• v.11 no.4
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• pp.409-414
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• 2013

The purpose of this study is to verify the effects of partial-cyber and full-cyber lectures and explore directions for improvement. This study compared the mean scores of course evaluation for traditional face-to-face lectures, partial-cyber lectures of blended instruction, and full-cyber lectures. Also, this study interviewed instructors of full-cyber lectures to investigate the ways to enhance the lecture quality. The findings suggest that the course evaluation scores for full-cyber university were consistently lower than those for other types of lectures for four semesters between the years of 2011 and 2012. Results also showed that mean scores of partial-cyber lectures were the same as those of face-to-face lectures. After all, class satisfaction in full-cyber courses that learning occurs in cyber space was the lowest. Instructors who taught full-cyber lectures proposed that enrollment should not be within 60 students and professional assistance should be provided for lectures exceeding 60 students. Finally, they suggested content updates through a collaborative system with professionals, instructors' efforts to enhance interaction in both online and offline contexts, and learning quantity rationalization.

• 한국초등상담교육학회:학술대회논문집
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• 2004.01a
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• pp.189-204
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• 2004

We can usually found the children who do overactive and aggressive behaviors. They disrupt classroom order and cause other children immense damage. Their teachers exert themselves to control or manage them in class. This may lead to a reduction of precious time for teaching-learning classroom activities. This study has counseled those children doing overactive and aggressive behaviors with solution-focused brief counseling. This study also explores the following problems. First, how does solution-focused brief counseling affect their overactive and aggressive behaviors? Second, what changes do they experience through solution-focused brief counseling? Third, is solution-focused brief counseling useful in elementary schools? To do this study task, four students have been chosen with the help of teachers in the fifth year at B Elementary School in Ansan. The four children scored high in Mi-hyun Han's 'The ratings of the child's behavior problems' and Se-Yong Jeong's 'Life of school and behavior test'. They are all eleven years old and had two interviews before the experiment and five interviews during the experiment. The analysis of the counseling has been interpreted according to the different analytical methods based on the tasks. Solution-focused brief counseling's effect on children doing overactive and aggressive behaviors has been studied by quantity-analysis method, their changes in behaviors by quality analysis method; phenomenal and psychological method and the usefulness of this counseling in school surroundings by the joint of above two methods. The analysis has provided the following results. First, solution-focused brief counseling has been effective in the reduction of behavioral problems for those children doing overactive and aggressive behaviors and the continuation of the counseling has had a positive effect but it has depended on the individual characteristics and the degree of severity in their behaviors. Second, solution-focused brief counseling has lent itself to encouraging children to have egostrength, confidence, and volition in their behavioral changes with a favorable attitude to the counseling. Third, The egostrength formed through counseling has led children to a progressive direction of their behaviors in their school life. The increasing frequency in counseling has caused a decreasing time-period expected for counseling, and a feasibility of counseling with less resistance. In conclusion, solution -focused brief counseling may be a useful means to help children have positive self-esteem and lead a proper school life, leading to be a helpful facilitation for school site facing a deficiency of counseling.

• Journal of Korean Society of Forest Science
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• v.76 no.3
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• pp.206-217
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• 1987

To investigate and analyze the vegetational structure, thirty sites were sampled with clumped sampling method and seventeen belt transects were sampled to analyze the vegetational change during 8 years(from 1978 to 1986)at the Namsan Nature Park in Seoul. Robinia pseudoacacia community of actual vegetation covered 29.39%, Quercus mongolica community 21.25% and Pinus densiflora community 17.58% of the Mt. Namsan forest. The degree of human disturbance of vegetation of 8, 7 and 6 area covered 43.2%, 7.8% and 30.8% respectively. The Quercus mongolica community at the northern slope and R. pseudoacacia community at the edge zone will keep their present structure. And P. densiflora community at the eastern and southern slope shall be succeeded to deciduous trees such as Q. mongolica. As to changes of plant community structure during 8 years, density of understory species, species diversity and Raunkiaer's frequency class A and E showed an increase and vegetation structure was developed to unification.

• Journal of Korean Academy of Nursing
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• v.24 no.4
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• pp.678-695
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• 1994

The purpose of this study was to investigate knowledge, attitudes and practices of women toward breast self-examination and to identify factors that may influence compliance with breast examination. The subjects for this study were 282 women in three hospitals located in In-Chun. Data were collected during the period from October 15 to 30, 1993 by means of a structured questionnaire. The data were analyzed using the SAS program and include descriptive statistics, 1-test, ANOVA, Pearson correlation coefficient and stepwise multiple regression. The results of study are as follows : 1. The mean knowledge score for the total sample was 13.58. Factors affecting the women's knowledge of breast cancer and BSE were : age, level of education, experience with breast cancer patients, experience in learning BSE, information about BSE, self-practice of BSE, level of intention to perform BSE, and participation in a BSE class. 2. Elements related to attitude included : (a) perceived feeling of susceptibility to breast cancer, and (b) belief about the effectiveness of BSE. The mean perceived susceptibility score was 1.62 and the mean effectiveness score was 4.22. Factors affecting the women's perceived susceptibility to breast cancer were exercise for health, level of intention to perform BSE , intention to recommend to others and self-practice of BSE. The relation between the womens' belief about effectiveness of BSE and level of intention to perform BSE and intention to recommend to others were statistically significant. 3. The mean self-practice score for the total sample was 4.01. Factors affecting the women's practice were experience with breast cancer patients, information about BSE, experience in learning BSE, enlisting the help of significant peers, and level of intention to perform BSE. Results indicated 35.8% of the total sample practiced BSE. The most frequent reason women gave for not performing BSE was “Didn’t knew about BSE technique”, “Didn’t think do it”. 4. No relation was found between knowledge and attitudes and practices. 5. When all the variables were examined for their contribution to the variance in the practice of BSE, it was found that confidence in ability to detect a mass by BSE, knowledge about breast cancer and BSE, and experience with breast cancer patients were significant variables and explained 35.8% of the variance. From the results of this study it can be said that women need to be taught proper BSE technique so they can become more proficient in detecting breast abnormalities.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 1993.05a
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• pp.79-84
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• 1993

This paper describes the development of lithium rechargeable cell. $LiCoO_2$ is recently recognized as a suitable cathode active material of a high voltage, high energy lithium rechargeable batteries because $Li^+$ ion can be electrochemically deintercalated/intercalated from/to $Li_xCoO_2$. The transition metal oxide of $LiCoO_2$ was investigated for using as a cathode active material of 4V class Li rechargeable cell. $LiCoO_2$ cathode was prepared by using a active material of 85 wt%, graphite powder of 12 wt% as a conductor and poly-vinylidene fluoride of 3 wt% as a binder. The electrochemical and charge/discharge properties of $LiCoO_2$ were investigated by cyclic voltammetry and galvanostatic charge/discharge. The open circuit voltage of prepared $LiCoO_2$ electrode exhibited approximately. potential range between 3.32V and 3.42V. During the galvanostatic charge/discharge, $LiCoO_2/Li$ cell showed stable cycling behavior at scan rate of 1mV/sec and potential range between 3.6V and 4.2V. Also its coulombic efficiency as function of cycling was 81%~102%. In this study the $LiCoO_2/Li$ cell showed the available discharge capacity of 90.1 mAh/g at current density of $1mA/cm^2$ and cell discharge voltage range between 3.6V~4.2V.

• Molecules and Cells
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• v.26 no.6
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• pp.536-547
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• 2008

Anthocyanidin synthase (ANS, leucoanthocyanidin oxygenase), a 2-oxoglutarate iron-dependent oxygenase, catalyzed the penultimate step in the biosynthesis of the anthocyanin class of flavonoids, from the colorless leucoanthocyanidins to the colored anthocyanidins. The full-length cDNA and genomic DNA sequences of ANS gene (designated as GbANS) were isolated from Ginkgo biloba for the first time. The full-length cDNA of GbANS contained a 1062-bp open reading frame (ORF) encoding a 354-amino-acid protein. The genomic DNA analysis showed that GbANS gene had three exons and two introns. The deduced GbANS protein showed high identities to other plant ANSs. The conserved amino acids (H-X-D) ligating ferrous iron and residues (R-X-S) participating in 2-oxoglutarate binding were found in GbANS at the similar positions like other ANSs. Southern blot analysis indicated that GbANS belonged to a multi-gene family. The expression analysis by real-time PCR showed that GbANS expressed in a tissue-specific manner in G. biloba. GbANS was also found to be up-regulated by all of the six tested abiotic stresses, UV-B, abscisic acid, sucrose, salicylic acid, cold and ethylene, consistent with the promoter region analysis of GbANS. The recombinant protein was successfully expressed in E. coli strain with pET-28a vector. The in vitro enzyme activity assay by HPLC indicated that recombinant GbANS protein could catalyze the formation the cyanidin from leucocyanidin and conversion of dihydroquercetin to quercetin, suggesting GbANS is a bifunctional enzyme within the anthocyanidin and flavonol biosynthetic pathway.