• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.285-286
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• 1998

Virtual Brain-endoscopy is an effective method to detect lesion in brain. Brain is the most part of the human and is not easy part to operate so that reconstructing in 3D may be very helpful to doctors. In this paper, it is suggested that to increase the reliability, method of matching 3D object with the 2D CT slice. 3D Brain-endoscopy is reconstructed with 35 slices of 2D CT images. There is a plate in 3D brain-endoscopy so as to drag upward or downward to match the relevant 2D CT image. Relevant CT image guides the user to recognize the exact part he or she is investigating. VRML Script is used to make the change in images and PlaneSensor node is used to transmit the y coordinate value with the CT image. The result is test on the PC which has the following spec. 400MHz Clock-speed, 512MB ram, and FireGL 3000 3D accelerator is set up. The VRML file size is 3.83MB. There was no delay in controlling the 3D world and no collision in changing the CT images. This brain-endoscopy can be also put to practical use on medical education through internet.

• 한국식품영양학회지
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• 제29권5호
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• pp.808-817
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• 2016

In this study, we investigated the effects of pre-soaking in salt and sugar solution prior to air drying at $50^{\circ}C$ on the characteristics of dried apples. Pre-soaking solutions included single solutions of salt 2% and sugar 2%; and combined solutions of salt 2%+sugar 2% and salt 2%+sugar 5%, respectively. The effects of pre-soaking condition and drying were evaluated in terms of moisture content (MC), water activity, color, antioxidant activity determined by DPPH radical scavenging activity, shear force, microbial contents, and sensory evaluation of apple slices. The control sample without pre-soaking showed the most rapid drying rate; in addition, the single solutions showed higher MC and water activity after drying time of 120 min, as compared to combined solutions. In all samples, MC and water activity showed high correlation coefficients of 0.91 to 0.97; whereas, shear force was negatively correlated with MC and water activity. The single solution of salt 2% showed decrease in change of color, including L, a, and b values, and the number of aerobic bacteria during drying. In addition, highest antioxidant activity and values of sensory preferences were observed in the dried apple pre-soaked in single solution of salt 2%.

• 대한약리학회지
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• 제32권2호
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• pp.139-150
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• 1996

The effects of adenosine analogues on the electrically-evoked norepinephrine(NE) release and the influence of ischemia on the effects were studied in the rat hippocampus. Slices from the rat hippocampus were equilibrated with $0.1{\mu}M$ $[^3H]-norepinephrine$ and the release of the labelled product, $[^3H]-NE$, was evoked by electrical stimulation(3 Hz, 2 ms, 5 $VCm^{-1}$ and rectangular pulses for 90 sec), and the influence of various agents on the evoked tritium-outflow was investigated. Ischemia(15min with 95% $N_2$ +5% $CO_2$) increased both the basal and evoked NE release. These increases were abolished by addition of glucose into the superfused medium, and they were significantly inhibited either by $0.3\;{\mu}M$ tetrodotoxin pretreatment or by removing $Ca^{++}$ in the medium. MK-801$(1{sim}10\;{\mu}M)$, a specific NMDA receptor antagonist, and glibenclamide $(1\;{\mu}M)$, a $K^+-channel$ inhibitor, neither alter the evoked NE release nor affected the Ischemia-Induced increases in NE release. However, polymyxin B(0.03 mg), a specific protein kinase C inhibitor, inhibited the effect of ischemia on the evoked NE release. Adenosine and $N^6-cyclopentyladenosine$ decreased the NE release in a dose-dependent manner in ischemic condition, though the magnitude of inhibition was far less than those in normal (normoxic) condition. Also the treatment with $5{\mu}M$ DPCPX, a potent $A_1-adenosine$ receptor antagonist did not affect the ischemia-effect. These results suggest that the evoked-NE release is potentiated by ischemia, and this process being most probably mediated by protein kinase C, and that the decrease of NE release mediated through $A_1-adenosine$ receptor is significantly inhibited in ischemic state.

• Journal of Communications and Networks
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• 제13권6호
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• pp.591-601
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• 2011

Today's Internet which provides communication channels with best-effort end-to-end performance is rapidly evolving into an autonomic global computing platform. Achieving autonomicity in the Future Internet will require a performance architecture that (a) allows users to request and own 'slices' of geographically-distributed host and network resources, (b) measures and monitors end-to-end host and network status, (c) enables analysis of the measurements within expert systems, and (d) provides performance intelligence in a timely manner for application adaptations to improve performance and scalability. We describe the requirements and design of one such "Future Internet performance architecture" (FIPA), and present our reference implementation of FIPA called 'OnTimeMeasure.' OnTimeMeasure comprises of several measurement-related services that can interact with each other and with existing measurement frameworks to enable performance intelligence. We also explain our OnTimeMeasure deployment in the global environment for network innovations (GENI) infrastructure collaborative research initiative to build a sliceable Future Internet. Further, we present an applicationad-aptation case study in GENI that uses OnTimeMeasure-enabled performance intelligence in the context of dynamic resource allocation within thin-client based virtual desktop clouds. We show how a virtual desktop cloud provider in the Future Internet can use the performance intelligence to increase cloud scalability, while simultaneously delivering satisfactory user quality-of-experience.

• 대한약리학회지
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• 제31권2호
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• pp.145-152
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• 1995

The effects and interactions of $4{\beta}-phorbol$ 12,13-dibutyrate(PDB) and polymyxin B(PMB) with adenosine on the electrically-evoked norepinephrine (NE) release were studied in the rat hippocampus. Slices from the rat hippocampus were equilibrated with $^3H-noradrenaline$ and the release of the labelled product, $^3H-NE$, which evoked by electrical stimulation$(3\;Hz,\;2\;ms,\;5\;VCm^{-1},\;rectangular\;pulses)$ was measured. PDB$(0.3{\sim}10\;{\mu}M)$, a selective protein kinase C(PKC) activator, increased the evoked NE release in a dose related fashion while increasing the basal rate of release. And the effects of $1\;{\mu}M$ PDB were significantly inhibited by $0.3\;{\mu}M$ tetrodotoxin(TTX) pretreatment or $Ca^{++}-free$ medium. $PMB(0.03{\sim}1\;mg)$, a specific PKC inhibitor, decreased the NE release in a dose dependent manner while increasing the basal rate of release. Adenosine $(1{\sim}10\;{\mu}M)$ decreased the NE release without changing the basal rate of release, and this effect was significantly inhibited by 8-cyclopentyl-1,3-dipropylxanthine$(2\;{\mu}M)$, a selective $A_1-receptor$ antagonist, treatment. Also, adenosine effects were significantly inhibited by PDB-and PMB-pretreatment. These results suggest that the PKC plays a role in the NE release in the rat hippocampus and might be participated in a post-receptor mechanism of the $A_1-adenosine$ receptor.

• 한국농공학회논문집
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• 제60권5호
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• pp.69-80
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• 2018

This study investigated climate change influences over crop water requirement (CWR) and irrigation water requirement (IWR) of the wheat-rice cropping system of Upper Chenab Canal (UCC) command in Punjab Province, Pakistan. PRECIS simulated delta-change climate projections under the A1B scenario were used to project future climate during two-time slices: 2030s (2021-2050) and 2060s (2051-2080) against baseline climatology (1980-2010). CROPWAT model was used to simulate future CWRs and IWRs of the crops. Projections suggested that future climate of the study area would be much hotter than the baseline period with minor rainfall increments. The probable temperature rise increased CWRs and IWRs for both the crops. Wheat CWR was more sensitive to climate-induced temperature variations than rice. However, projected winter/wheat seasonal rainfall increments were satisfactorily higher to compensate for the elevated wheat CWRs; but predicted increments in summer/rice seasonal rainfalls were not enough to complement change rate of the rice CWRs. Thus, predicted wheat IWRs displayed a marginal and rice IWRs displayed a substantial rise. This suggested that future wheat production might withstand the climatic influences by end of the 2030s, but would not sustain the 2060s climatic conditions; whereas, the rice might not be able to bear the future climate-change impacts even by end of the 2030s. In conclusion, the temperature during the winter season and rainfall during the summer season were important climate variables controlling water requirements and crop production in the study area.

• Restorative Dentistry and Endodontics
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• 제41권2호
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• pp.114-120
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• 2016

Objectives: The aim of this study was to compare the push-out bond strength and dentinal tubule penetration of root canal sealers used with coated core materials and conventional gutta-percha. Materials and Methods: A total of 72 single-rooted human mandibular incisors were instrumented with NiTi rotary files with irrigation of 2.5% NaOCl. The smear layer was removed with 17% ethylenediaminetetraacetic acid (EDTA). Specimens were assigned into four groups according to the obturation system: Group 1, EndoRez (Ultradent Product Inc.); Group 2, Activ GP (Brasseler); Group 3, SmartSeal (DFRP Ltd. Villa Farm); Group 4, AH 26 (Dentsply de Trey)/gutta-percha (GP). For push-out bond strength measurement, two horizontal slices were obtained from each specimen (n = 20). To compare dentinal tubule penetration, remaining 32 roots assigned to 4 groups as above were obturated with 0.1% Rhodamine B labeled sealers. One horizontal slice was obtained from the middle third of each specimen (n = 8) and scanned under confocal laser scanning electron microscope. Tubule penetration area, depth, and percentage were measured. Kruskall-Wallis test was used for statistical analysis. Results: EndoRez showed significantly lower push-out bond strength than the others (p < 0.05). No significant difference was found amongst the groups in terms of percentage of sealer penetration. SmartSeal showed the least penetration than the others (p < 0.05). Conclusions: The bond strength and sealer penetration of resin-and glass ionomer-based sealers used with coated core was not superior to resin-based sealer used with conventional GP. Dentinal tubule penetration has limited effect on bond strength. The use of conventional GP with sealer seems to be sufficient in terms of push-out bond strength.

• Restorative Dentistry and Endodontics
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• 제46권2호
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• pp.22.1-22.12
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• 2021

Objectives: This study evaluated and compared the effects of radiation therapy on the dislocation resistance of AH Plus and BioRoot RCS applied to dentin and the sealer-dentin interface. Materials and Methods: Thirty single-rooted teeth were randomly assigned to 2 groups (n = 15 each): AH Plus (Dentsply DeTrey) and BioRoot RCS (Septodont). Each group was subdivided into control and experimental groups. The experimental group was subjected to a total radiation dose of 60 Gy. The root canals of all samples were cleaned, shaped, and obturated using the single-cone technique. Dentin slices (1 mm) were sectioned from each root third for the push-out test and scanning electron microscopy (SEM) was done to examine the sealer-dentin interface. The failure mode was determined using stereomicroscopy. Bond strength data were analyzed by the independent t-test, 1-way analysis of variance, and the Tukey post hoc test (α = 0.05). Results: Significantly lower bond strength was observed in irradiated teeth than non-irradiated teeth in the AH Plus group (p < 0.05). The BioRoot RCS group showed no significant reduction in bond strength after irradiation (p > 0.05) and showed a higher post-irradiation bond strength (209.92 ± 172.26 MPa) than the AH Plus group. SEM revealed slightly larger gap-containing regions in irradiated specimens from both groups. Conclusions: The dislocation resistance of BioRoot RCS was not significantly changed by irradiation and was higher than that of AH Plus. BioRoot RCS may be the sealer of choice for root canal treatment in patients undergoing radiation therapy.

• 한국식품영양과학회지
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• 제38권8호
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• pp.1124-1129
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• 2009

소비자의 다양한 기호 변화에 맞추어 칼라 푸드에 접목하기 위해 비트 물 추출물을 첨가한 연근 피클을 제조하여 품질변화 및 관능평가를 실시한 결과는 다음과 같다. 제조 직후 연근 피클의 pH는 3.5$\sim$3.51이었는데, 저장기간이 경과함에 따라 pH가 감소하여 비트 물 추출물을 넣지 않은 대조군은 3.45이었고, 비트 물 추출물 첨가군은 완만하게 감소하여 3.47$\sim$3.48을 나타내었다. 저장기간 중의 산도는 pH가 내려감에 따라 증가하여 대조군의 경우는 제조 직후 1.50%에서 저장 35일째에는 1.88%로 증가되었고, 비트 물 추출물 첨가군은 제조 직후 1.40$\sim$1.70%에서 저장 35일째에 1.70$\sim$1.80%로 증가하는 경향을 나타내었다. L(명도) 값은 대조군이 가장 높았고, 비트 물 추출물 첨가량이 증가할수록 낮아지는 경향을 나타냈으며 적색도(a) 값은 비트 물 추출물 첨가량이 많을수록 높게 나타났으나 저장기간이 증가함에 따라 감소하였다. 황색도(b) 값은 저장기간이 길어질수록 증가하는 경향을 나타냈다. 저장기간이 경과됨에 따라 경도는 낮아졌는데, 대조군과 비트 물 추출물 첨가 연근 피클 간에는 유의한 차이가 있었으나(p<0.05) 비트 물 추출물 첨가군간에는 유의한 차이가 없었다. 저장 21일째 연근 피클 색의 바람직한 정도는 비트 물 추출물 30% 첨가군이 가장 높게 평가되었다. 맛은 대조군이 가장 낮았고, 비트 물 추출물 첨가 연근 피클 간에 유의적인 차이를 보였으며, 30% 비트물 추출물 연근 피클이 가장 높은 점수를 받았다. 냄새(상큼한 신 냄새)는 비트 물 추출물 첨가량이 많아질수록 유의적으로 높게 나타나 40% 비트 물 추출물 첨가 연근 피클의 경우 상큼한 신 냄새가 가장 강했다. 조직감 특성은 대조군이 3.81, 비트 물 추출물 첨가량이 많을수록 3.88$\sim$4.65로 높게 나타났다. 전반적인 기호도는 30% 첨가군이 가장 높게평가되었다.

• 대한핵의학회지
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• 제26권2호
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• pp.307-311
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• 1992

Anorexia, nausea, and vomiting are one of the most frequent symptoms in viral hepatits patients. These may be due to poorly detoxified substances by dysfunctioned hepatocytes or by gastritis, but the pathophysiology is not totally understood. The symptoms interfere with adequate nutrient intake and are managed by metoclopramide, which accelerates gastric emptying. Thus delayed gastric emptying may well be a contributing factor to such symptoms. To determine such a relationship, we measured gastric emptying time in 11 normal subjects,9 acute (AVH), and 12 chronic B viral hepatitis (CVH) patients. All were males with a mean age of 23 years. An egg was labeled with 0.5 mCi of $^{99m}Tc-sulfur$ colloid, fried, then eaten between 2 slices of bread with 100 cc of water. Anterior and posterior images were taken at 20 minute intervals over a 2 hour period. A geometric mean of activity pertaining to the gastric region was measured, and $T_{1/2}$ was calculated from the time activity curve. $T_{1/2}$ for normal the group was $57.8{\pm}6.3$ minutes while that for the AVH and CVH group was $58.2{\pm}8.2$ (p=0.40) and $64.1{\pm}10.5$ (p=0.09), respectively. There was 1 AVH Patient and 4 CVH patients with prolonged $T_{1/2}$. Anorexia and nausea was seen in 71% and 46% of the patients, respectively. 80% and 60% of the patients with prolonged $T_{1/2}$ had anorexia and nausea, respectively.