• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.3 no.2
• /
• pp.169-174
• /
• 2000

Purpose: Previously reported ocular complications of interferon alfa administration are extremely rare. We experienced a 15-year-old boy with chronic hepatitis B who developed glaucoma after interferon alfa therapy. The purpose of this prospective study was to evaluate the possible development of glaucoma after interferon alfa therapy for chronic hepatitis B. Methods: Nine patients with chronic hepatitis B who visited Inha university hospital between February 1998 and July 1999 received interferon alfa therapy. We measured visual acuity, intraocular pressure, C/D ratio, and visual field examination at pre-interferon therapy, three and six months after therapy, respectively. Results: The total number of patients was 9 (4 boys and 5 girls). Mean age was $11.7{\pm}4.1$ years. The duration of therapy was 6 months and mean dosage of interferon was 5 million units. Compared with visual acuity, intraocular pressure, and C/D ratio at pre-therapy, those parameters at 3 months and 6 months after therapy showed no significant differences and none showed visual field defect after therapy. Conclusion: Our prospective study showed no evidence of development of glaucoma after interferon therapy. However, it is necessary to be concerned about the possibility of developing glaucoma or other ophthalmologic diseases after interferon therapy in chronic hepatitis B.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.10 no.2
• /
• pp.166-172
• /
• 2007

Purpose: It has recently been reported that de novo HBV infection following liver transplantation is caused by grafts from HBcAb positive donors, and this phenomenon has been observed in one third of the liver transplant patients in our center. Therefore, we investigated the presence of HBV virus DNA in liver tissues obtained from HBcAb positive donors to determine the mechanism by which de novo HBV infection occurs. Methods: This study was conducted on 6 patients that were HBsAg negative, HBsAb positive, and HBcAb positive who were donors for liver transplantation between November 1997 and November 1998 at Asan Medical Center. We isolated DNA from a portion of liver biopsy tissues that were obtained during the operation, and then identified the surface and core region of HBV DNA using nested PCR. In addition, four children who received liver grafts from these donors were monitored to determine if they became afflicted with non-HBV related diseases while receiving prophylaxis consisting of short-term HBIG treatment and long-term treatment with an antiviral agent. Results: The surface antigen region was identified in all 6 donors and the core antigen region was observed in 4 of the 6 donors. However, no episodes of de novo HBV infection with prophylaxis were observed. Conclusion: The results of this study support the results of previous studies, which indicated that HBV infection may be the main cause of de novo HBV infection in patients that receive HBsAb positive and HBcAb positive donor grafts.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.37 no.2
• /
• pp.95-105
• /
• 2001

A series of experiment is carried out to determine the holding power of the existing anchors used in the stationary gear in the coast of the South sea. The experiment apparatus is made of the pulling machine, the load cell, the personal computer and three water tanks the bottom of which are mud, sand and m & s respectively. The result obtained are as follows : 1. On the tension and holding power of the existing anchors, B-type of the stock anchor with two fluke shows the greatest and gets smaller on order of A-type one with a fluke. The holding power of the anchors shows the greatest in the mud and gets smaller in order of m & s, sand. And, the holding power depending upon the length of anchor rope increase as the length does up to the 4 times of depth. 2. On the holding power per fluke area of the existing anchors in case of ration of length of anchor rope to depth is 2, 3 and 4, A-type anchor shows about 310-320 kg/m supper(2), 470-480 kg/m supper(2), 590-640 kg/m supper(2) respectively, B-type one 260-265 kg/m supper(2), 390-450 kg/m supper(2), 630-700 kg/m supper(2) respectively, and C-type one 70-100 kg/m supper(2), 150-180 kg/m supper(2), 210-270 kg/m supper(2) respectively. The holding power per fluke area of the anchors increase as the length of anchor rope does. 3. On the coefficient of holding power of the existing anchors, A-type anchor shows the greatest and gets smaller in the order of B-type one, C-type one.

• The Journal of Dong Guk Oriental Medicine
• /
• v.8 no.1
• /
• pp.93-106
• /
• 1999

For the purpose of investigate the inhibition effects of Injinchunggantang on Hepatitis and C Virus. The inhibition experiments were as follows : 1. The inhibition effects of Hepatitis B surface antigen production was remarkably increased in the pretreated group of Injinchunggantang compared with control group. 2. Amplified PCR products of HBV-DNA in culture media was considerably decreased in the pretreated group of Injinchunggantang compared with control group. 3. Results of ATP quantitation and ATPase inhibition percent was increased pretreated group of Injinchunggantang. Also ATPase activity of HCV helicase inhibition assay was increased with a dose dependent manner. These results may suggest that Injinchunggantang will have the inhibition effects of Hepatitis B and C Virus.

• Journal of agricultural medicine and community health
• /
• v.47 no.2
• /
• pp.99-108
• /
• 2022

Objectives: This study aimed to identify the vaccination coverage for hepatitis B among aged 19 or older, and at the same time to determine the reasons for vaccination or non-vaccination. Methods: The survey was conducted through a Mixed-Mode Random Digit Dialing Survey (RDD) method. The survey included hepatitis B vaccination status, reasons of vaccination and non-vaccination, sources of information on vaccination, and other related factors. Results: The vaccination coverage for hepatitis B among adults 19 years of age and older were 38.0%, 32.5%, and 26.9% for the first, second, and third doses. A related factors with high rate of hepatitis B vaccination was women, younger than 65 years of age, rural residents, having a job, highly educated, health insurance subscribers, living with spouse, family members living together. In addition, the vaccination rate was higher in those who was aware of the states recommended adult vaccination, were explained by a doctor about the need for adult vaccination, kept their vaccination records, and recognized that it helped prevent infectious diseases, and had seen promotional materials. Conclusions: In the future, it is necessary to check the antibody retention rate along with the hepatitis B vaccination coverage of adults on a regular basis. In addition, in order to accurately and quickly identify the hepatitis B vaccination coverage, it is necessary to prepare a plan to improve the computerized registration rate to manage adult vaccination records.

• Proceedings of the Korean Radioactive Waste Society Conference
• /
• 2004.06a
• /
• pp.434-434
• /
• 2004

하나로에서 생산되는 방사성 동위원소를 생산단계에서 소비단계까지의 유통체계를 확립하기 위해서는 방사성동위원소를 안전하게 운반하기 위한 운반용기를 개발하여야 한다. 따라서, 원자력연구소에서는 Ir-192 110 ci용 밀봉선원 조사기를 개발하고 있다. 이 조사기는 국내ㆍ외 방사성물질 운반용기관련 법규의 운반용기 분류기준에 의하면 B형 운반용기로 분류된다. B형 운반용기는 관련법규에서 규정하고 있는 $800^{\circ}C$ 열 조건에서 30분 이상 동안 견딜 수 있는 능력을 갖추어야 한다.(중략)

• Environmental Mutagens and Carcinogens
• /
• v.11 no.2
• /
• pp.134-140
• /
• 1991

B형 간염바이러스의 표면항원, 파상풍, 디프테리아균의 toxoid, 백일해의 혼합백신인 PDT-Hepa의 효능을 실험하여 다음과 같은 결과를 얻었다. 시험물질을 기니픽에 접종하였을 때 B형 간염 바이러스의 표면 항원과 파상풍 및 디프테리아균의 toxoid에 대한 항체형성이 뚜렷이 관찰되었으며, 항체형성의 정도는 접종용량에 비례하였다. 백일해의 경우는 시험물질을 마우스에 접종시킨 후 마우스에 감수성이 있는 Bordetella pertussis 18323주로 직접 공격 접종하여 이 균에 대한 방어력이 형성되어 있음을 관찰하였으며, 이러한 방어정도는 투여 용량에 비레함을 알 수 있었다.

• 대한예방의학회:학술대회논문집
• /
• 1996.10a
• /
• pp.141-142
• /
• 1996

• 건강소식
• /
• v.15 no.5 s.150
• /
• pp.8-9
• /
• 1991

• The Korean Chronic Disease News
• /
• no.67
• /
• pp.7-7
• /
• 1986