• Archives of Pharmacal Research
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• 제27권10호
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• pp.985-989
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• 2004

A functional divergency oriented synthetic approach to the azoninone (9-membered lactams), key intermediate for the indolizidine alkaloids library, using amide enolate induced aza-Claisen rearrangement has been achieved.

• Bulletin of the Korean Chemical Society
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• 제29권10호
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• pp.1998-2004
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• 2008

Two synthetic pathways to substituted hexahydroimidazo[1,2-a]pyridines, which may serve as precursors of aza-alkaloids, were investigated. The first involves the condensation of a bisnucleophilic enediaminoester and a biselectrophile. The second involves attachment to nitrogen of the carbon chain skeleton required to form the six-memberd ring, before formation of the enediaminoester. Several substituted hexahydroimidazo[1,2- a]pyridines were synthesized via these two approaches.