• 셀메드
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• 제12권1호
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• pp.2.1-2.9
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• 2022

The study has been carried out for the comparative analysis of relevant literature in order to highlight the present topic "Clinical study on effect on Virechana karma (therapeutic purgation)". Total no. of 40 cases has been selected from OPD and IPD of Panchakarma department, through proper history taking and clinical examination prior to VirechanaKarma. Only VirechanaKarmaYogya subjects were selected for the VirechanaKarma. Analysis of VirechanKarma on the basis of Vegiki (purgative bouts), Maniki (quantity), Langiki (clinical features) and Aantiki (end product) features were done in this study. In this study a highly significant relief was found in patients i.e. p<0.001 due to Virechana mainly vitiated PittaDosha (the heat energy in the body) and secondary Kaphadosha (mucus) and VataDosha (subtle energy associated with movement) are being expelled out which might have accounted for better relief in VirechanYogya (indicated) individuals (Pitta Pradhan Vyadhi (vitiated pitta), RaktajRoga (hemopoietic diseases), ShodhanYogyaAvastha (detoxification), etc.) in the above group of patients. VirechanaDravyas have properties like Tikshna (hyperfunction), Sukshma(subtle), Ushna (heat), etc. are described in Ayurvedic classics which play a vital role in the mode of action of VirechanaKarma has also been explained under probable mode of action.

• 패션비즈니스
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• 제13권6호
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• pp.45-60
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• 2009

This study examined the efficacy of restraining the increase of the bacteria colony of scalp according to the application of the Ayurvedic base oils and essential oils to scalp and hair. The result is as follows. The experiment illustrated that as the result of doing the paired sample t-test of a treated group and a control group according to constitutional oiling, the efficacy of the statistically significant decrease of the colony manifested in six tested groups except the group of Pitta constitution to which sesame and lavender were applied. Also, in a group that sesame was applied to Vata constitution and a group that coconut and lavender were applied to Pitta constitution, according to the passage of time, the result of being reduced the number of the colony was obtained and it showed that the oiling suitable for each constitution has the efficacy to decrease the colony of scalp. At the same time, regardless of the constitutions, the application of oils also showed the efficacy of restraining the increase of the bacteria colony of scalp. As the result of performing Paired Sample t-test for the subjective evaluation of the subjects in pre and post clinical testing, In the analysis of questionnaire that were obtained before and after the clinical testing, the results of all of the items except the item questioning a degree of inflammation appeared to be significant. That is to say, the subjects answered that a degree of keratin or a pain in scalp, an amount of sebum and a degree of hair damage were decreased after the application of oil more than before it. And in the question of a degree of hair damage, the application of oils were proved as having the efficacy to improve the hair damage.

• Asian Pacific Journal of Cancer Prevention
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• 제15권11호
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• pp.4405-4409
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• 2014

Reactive oxygen species (ROS), highly reactive molecules, are produced by living organisms as a result of normal cellular metabolism and environmental factors, and can damage nucleic acids and proteins, thereby altering their functions. The human body has several mechanisms to counteract oxidative stress by producing antioxidants. A shift in the balance between oxidants and antioxidants in favor of oxidants is termed as "oxidative stress". Paradoxically, there is a large body of research demonstrating the general effect of oxidative stress on signaling pathways, less is known about the initial and direct regulation of signaling molecules by ROS, or what we term the "oxidative interface." This review focuses on the molecular mechanisms through which ROS directly interact with critical signaling molecules to initiate signaling in a broad variety of cellular processes, such as proliferation and survival (MAP kinases and PI3 kinase), ROS homeostasis, and antioxidant gene regulation (Ref-1 and Nrf-2). This review also deals with classification as well as mechanisms of formation of free radicals, examining their beneficial and deleterious effects on cellular activities and focusing on the potential role of antioxidants in preventing and repairing damage caused by oxidative stress. A discussion of the role of phytochemical antioxidants in oxidative stress, disease and the epigenome is included.

• 대한한의학회지
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• 제29권1호
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• pp.25-38
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• 2008

Objectives : Integrative medicine in Korea is the 21st century-style medical practice of two orthodox medical doctrines, traditional Korean medicine and western conventional medicine, as well as complementary and alternative medicine (CAM). CAM with scientific evidence should be incorporated in undergraduate curricula for the purpose of Korean integrative medicine. Methods : Items of detailed objectives, syllabi, textbooks, instructor's experiences, and effectiveness and reason for difficulty of the CAM curriculum for undergraduate students were analyzed and the preference of CAM therapies and others were also evaluated. Results and Discussion : The effectiveness of this CAM class curriculum was high (8.0$\pm$1.4) enough to be used in other Oriental medical colleges. Development of ability for self-study was rated as 7.0$\pm$1.7 and the helpfulness for clinical use was marked as 6.8$\pm$1.9. Students preferred placebo, Ayurveda, aromatherapy, yoga, functional food, bio-feedback and homeopathy. The difficulty degree was 7.2$\pm$1.6, and the amount of content was suggested as the major reason for it. We also found that this curriculum can be a model for self-oriented study and problem-based learning. Discussions were made for the improvement of the implemented CAM curriculum, which was shown to be very effective for the achievement of Korean integrative medicine. Conclusion : We have successfully installed a CAM curriculum for undergraduate students at the College of Oriental Medicine, and it can be used in others.

• 셀메드
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• 제10권1호
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• pp.7.1-7.6
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• 2020

Plants produce a wide range of active principles, making them a rich source of different types of medicines. Without any knowledge of the phytoconstituents or active principles the medicinal plants itself or in the form of polyherbal formulations, were used by all society of human being from ancient times for prevention and cure of disease, but most of the traditional formulations including the formulation of Ayurveda and Unani have not been scientifically validated in order to establish the pharmacopoeial standards to improve the efficacy. Globally, the people become conscious that uses of synthetic drugs for a long period is not safe; the trend of medical society at large is looking at alternatives from natural, safe sources to combat diseases. Due to this comprehension, it has been increased the demand for plant-derived medicine, and on the other side, it is extremely important to standardize the polyherbal formulations and validate them scientifically to improve their safety and efficacy. The polyherbal Unani formulation Safuf-e-Muallif is widely used and recommended in Unani system of medicine (USM) as a spermatogenic agent, semen thickening agent, etc. to treat sexual disorders viz. premature ejaculation, nocturnal emission, etc. The study mainly deals with phytochemical screening for the detection of nature of phytoconstituents and analytical technique like High-performance thin-layer chromatography (HPTLC) for developing fingerprint of Safuf-e-Muallif revealing specific identities of the drug. The phytochemical screening and HPTLC fingerprint profile for SM reported here may be used as a reference standard for quality control purpose in future.

• Journal of Periodontal and Implant Science
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• 제44권3호
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• pp.134-140
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• 2014

Purpose: Triphala is a combination of three medicinal plants, extensively used in Ayurveda since ancient times. Triphala mouthwash is used in the treatment of periodontal diseases because of its antimicrobial and antioxidant properties. The aim of this study is to compare the efficacy of triphala mouthwash with 0.2% chlorhexidine in hospitalized periodontal disease patients. Methods: In this double-blind, randomized, multicenter clinical trial, 120 patients were equally divided into three groups. Patients in group A were advised to rinse their mouths with 10 mL of distilled water, group B with 0.2% chlorhexidine, and group C with triphala mouthwash for 1 minute twice daily for two weeks. The plaque index (PI) and the gingival index (GI) were recorded on the first and the fifteenth day. Results: There was no significant difference when the efficacy of triphala was compared with 0.2% chlorhexidine in hospitalized patients with periodontal disease. However, a statistically significant difference was observed in PI and GI when both group B and group C were compared with group A and also within groups B and C, after 15 days (P<0.05). Conclusions: The triphala mouthwash (herbal) is an effective antiplaque agent like 0.2% chlorhexidine. It is significantly useful in reducing plaque accumulation and gingival inflammation, thereby controlling periodontal diseases in every patient. It is also cost effective, easily available, and well tolerable with no reported side effects.

• 셀메드
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• 제2권2호
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• pp.12.1-12.11
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• 2012

Traditional Medicinal System (TMS) is one of the centuries-old practices and long-serving companions to the human kind to fight against disease and to lead a healthy life. Every indigenous people have been using their unique approaches of TMS practice where among, the Chinese, Indian and African TMSs are world-wide renowned. India has a unique Indian System of Medicines (ISM) consisting of Ayurveda, Siddha, Unani, Naturopathy and Homoeopathy. Siddhars are the saints as well as the eminent scholars, who have attained Ashta-mahasiddhi [Tamil: (Ashta-Eight; Mahasiddhi-Power)] or enlightment. They have postulated, practiced, immensely contributed and have established the concept of the Tamil medicinal system called Siddha System of Medicine (SSM). From ancient time, SSM has flourished and has been widely practiced in the southern part of India particularly in Tamil Nadu. The induction of the modern medicinal system has immensely influenced the existence of SSM and has made the SSM principles and practices undervalued/extinct. However, at present, still a considerable group of people are using the SSM as a basic health-care modality. In this context, the present scrutiny deals with the TMS history, its significance with a special reference to SSM history, Siddhars, the basic concept of SSM, its diagnostic procedures, materia medica and treatment. Conclusively, Siddha is one of the most ancient indigenous health practices despite its several thorny challenges and issues, which needs to be flagged effectively and to be preserved and revitalized in the international arena in the near future.

• 한국산학기술학회논문지
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• 제9권6호
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• pp.1800-1805
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• 2008

시로아비앙가는 인도의 고대의 의학서이면서 건강관리의 지침서인 아유르베다의 한 시술법이다. 본 연구는 시로아비앙가가 스트레스 완화에 미치는 효과를 20대 여성을 대상으로 살펴보았다. 이 실험은 뇌파측정을 통해 알아보았는데, 시로아비앙가 마사지가 좌뇌의 델타파와 우뇌의 델타파, 세타파를 떨어뜨리고, 우뇌의 알파파와 SMR파, 로우베타파는 증가시키는 것으로 나타났다. 수면 시에 나타나는 델타파와 세타파가 깨어있을 때 높게 나타난 것은 대상자가 스트레스와 긴장상태에 있음을 의미하고, 시로아비앙가 마사지 이후에 델타파와 세타파가 감소하는 결과는 긴장상태가 완화됨을 나타낸다. 뇌가 활동하고 있을 때 나오는 알파파는 심신이 이완되어 편안할 때 가장 많이 나오는 뇌파이다. 따라서 알파파가 시로아비앙가 마사지 후 증가하는 점은 시로아비앙가 마사지가 스트레스 완화에 영향을 미침을 알 수 있다.

• The Korean Journal of Physiology and Pharmacology
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• 제15권5호
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• pp.285-289
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• 2011

Shilajit, a medicine herb commonly used in Ayurveda, has been reported to contain at least 85 minerals in ionic form that act on a variety of chemical, biological, and physical stressors. The substantia gelatinosa (SG) neurons of the trigeminal subnucleus caudalis (Vc) are involved in orofacial nociceptive processing. Shilajit has been reported to be an injury and muscular pain reliever but there have been few functional studies of the effect of Shilajit on the SG neurons of the Vc. Therefore, whole cell and gramicidin-perfotrated patch clamp studies were performed to examine the action mechanism of Shilajit on the SG neurons of Vc from mouse brainstem slices. In the whole cell patch clamp mode, Shilajit induced short-lived and repeatable inward currents under the condition of a high chloride pipette solution on all the SG neurons tested. The Shilajit-induced inward currents were concentration dependent and maintained in the presence of tetrodotoxin (TTX), a voltage gated $Na^+$ channel blocker, CNQX, a non-NMDA glutamate receptor antagonist, and AP5, an NMDA receptor antagonist. The Shilajit-induced responses were partially suppressed by picrotoxin, a $GABA_A$ receptor antagonist, and totally blocked in the presence of strychnine, a glycine receptor antagonist, however not affected by mecamylamine hydrochloride (MCH), a nicotinic acetylcholine receptor antagonist. Under the potassium gluconate pipette solution at holding potential 0 mV, Shilajit induced repeatable outward current. These results show that Shilajit has inhibitory effects on the SG neurons of Vc through chloride ion channels by activation of the glycine receptor and $GABA_A$ receptor, indicating that Shilajit contains sedating ingredients for the central nervous system. These results also suggest that Shilajit may be a potential target for modulating orofacial pain processing.

• 한국자연치유학회지
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• 제10권1호
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• pp.56-65
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• 2021

목적: 본 연구는 아유르베다 사상을 통해 현대 서양 과학과 철학의 한계의 원인을 고찰하고, 치유사업 발전을 위한 홀리즘의 길을 모색하고자 하였다. 이에 현대 서양 문명이 오늘의 한계에 이르게 된 배경과 치유사업의 현실이 그맥을 함께 할 것이라 추론하였다. 방법: 이를 살펴보기 위해 동서양의 '몸과 마음에 대한 인식'의 차이와 '존재의 근원에 대한 관점'의 차이를 살펴보고 이에 따른 아유르베다 5원소설의 특징을 살펴보았다. 결과: 그 과정을 통해 서양의 '심신이원론'과 서양 4원소설에서의 '공(空)요소'의 부재'를 한계의 원인으로 지목하게 되었다. '공(空)요소'가 보이지 않는 세계, 비물질의 세계라는 점에서 공의 부재가 서양 문명의 한계인 동시에 국가 치유사업 현실의 문제라고 결론짓게 되었다. 결론: 본 연구가 아유르베다 사상의 지속적인 연구와 자연치유 분야의 연구로 이어져 치유사업의 발전의 기초정보가 되고, 국민의 건강과 웰빙·자기치유를 기대하여 본다.