• Perspectives in Nursing Science
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• 제2권1호
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• pp.61-75
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• 2005

Physical and psychological events can produce stress response in various degrees. Stress affects many aspects of physiology including both brain and peripheral elements which is represented as hypothalamus-pituitary-adrenal axis. Brain elements consist of corticotropin-releasing hormone(CRH), locus ceruleus(LC)-norepinephrine(NE)/autonomic system. Peripheral elements include pituitary-adrenal axis and the autonomic nervous system, which coordinate the stress response. Current trend of the stress researches is emphasizing the mechanisms of the stress response which is adaptive or become maladaptive. This review introduces 1) the concepts of stress, 2) physiological and behavioral aspects of stress responses, 3) the consequences of stress response, 4) the measurements of stress and 5) stress management for those interested in stress research.

• 대한한의진단학회지
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• 제15권2호
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• pp.127-140
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• 2011

Objectives: Acupuncture has been shown to relieve pain and modulate biological function by stimulating the organ-specific meridians and enhances parasympathetic activity and suppresses sympathetic activity. The aim of this review is to summarize and understand the effects of acupuncture on autonomic nervous system. Methods: We reviewed a total of 29 studies published from 2000 to 2010 searched by PueMed and various domestic oriental medicine journals to obtain acupuncture studies related with ANS. Each article was classified by ANS measurement index and reviewed for study objectives, outcomes, acupuncture points, experimental and control interventions. Results: In the study of acupuncture about EEG, HRV, SCR, the experiment results are not the same by acupoints. Although same acupoint the results differ by subject's condition. But the study showed some clear tendency. In brief, in normal states acupuncture enhanced either vagal or sympathetic tone depending on the stimulated acupuncture point sites. On the other hand, most of studies demonstrated that acupuncture restored the autonomic dysfunctions in various kinds of tired or stressful states. Conclusions: We reviewed studies that contributed to an understanding of the effects and mechanisms of acupuncture on autonomic nervous system. Although the relationship between acupuncture and ANS response is still uncertain, acupuncture could be a excellent treatment method for modulating autonomic dysfunction.

• 대한임상전기생리학회지
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• 제7권1호
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• pp.7-10
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• 2009

Purpose : The purpose of this study was to investigate the effect of electrical stimulation applied in dominant forearm on autonomic nervous system response of both hands. Methods : Fourteen healthy subjects (women) received low frequency-high intensity electrical stimulation to one forearm. The subjects assigned to two groups; a ipsilateral stimulation group (n=7) and a contralateral stimulation group (n=7). The electrode attachment was arranged on the forearm of the dominant arm and the electricity stimulus time was set as 15 minutes. Measuring items were the skin conduction velocity, the blood flow, and the pulse rate, which were measured total 3 times (pre, post, and post 10 min.). Results : The skin conduction velocity showed a significant difference according to the change of the time in both hands, but there was no significant difference according to time in the blood flow, and the change of the pulse frequency regardless of stimulus side. Conclusion : These results demonstrate that the low frequency-high intensity electrical stimulation applied dominant forearm can increase selectively only with the skin conduction velocity, which may be helpful for the activation of the sudomotor function of both hands by the activation of sympathetic nerve.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2011년도 추계학술대회
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• pp.3-4
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• 2011

• 대한한방내과학회지
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• 제31권4호
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• pp.837-845
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• 2010

It has been shown that bilateral decrease of point H4,5,6 in Ryodoraku test is related with gastric dysmotility. This suggested that the system of Kyung-Rak related with anatomical gastric disease may not be the Stomach Meridian, in the view that the system of Kyung-Rak is similar to that of Ryodoraku, and which was not consistent with classical contents of Kyung-Rak principle. Therefore, this paper was done to investigate whether bilateral decrease of point H4,5,6 is a general sign of common gastric disease in Ryodoraku test and to study its relation between Kyung-Rak principle and autonomic nervous system as a mediator explaining Ryodoraku response. As shown in the results of this study, different electrical response of Ryodoraku between patients with dyspepsia of gastric dysmotility and gastric ulcer revealed discrepancy of location indicating anatomical stomach between Kyung-Rak principle and Ryodoraku and instability of explanation of autonomic nerve theory to Ryodoraku. Thus, it presented the possibility that artificial application of Kyung-Rak principle against Ryodoraku may destroy its originality in the clinical field. To correctly use Ryodoraku in the diagnosis or evaluation of disease, Ryodoraku test should be used according to Nakatani's suggestion and clinical indication of which is limited to the diseases complicated with dysfunction of the autonomic nervous system.

• The Korean Journal of Pain
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• 제35권3호
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• pp.327-335
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• 2022

Background: The pathophysiology of fibromyalgia (FM) involves many mechanisms including central nervous system sensitization theory, autonomic nervous system (ANS) dysfunction, and recently small fiber neuropathy. While the small fiber neuropathy itself can cause ANS dysfunction and neuropathic pain (NP), it is still unknown whether ANS problems have an association with severity of disease and NP in patients with FM. The aim of this study was to evaluate ANS dysfunction in FM patients and to explore possible associations of ANS dysfunction with disease severity and NP. Methods: Twenty-nine FM patients and 20 healthy controls were included in this cross-sectional study. Participants were tested using sympathetic skin responses (SSR) and R-R interval variation analyses for sympathetic and parasympathetic ANS dysfunction, respectively. Disease severity and somatic symptoms of patients with FM were evaluated using the ACR-2010 scales and Fibromyalgia Impact Questionnaire, and NP symptoms were evaluated using the Pain Detect Questionnaire and Douleur Neuropathique questionnaire. Results: FM patients were found to have ANS dysfunction characterized by increased sympathetic response and decreased parasympathetic response. SSR amplitudes were found to be correlated with a more severe disease. Although nonsignificant, NP severity tended to be associated with a decrease in sympathetic and parasympathetic activities. Conclusions: ANS dysfunction may play a role in the pathophysiology of FM. The trend of decreased ANS functions in FM patients exhibiting NP contradicts the notion that FM is a sympathetically maintained NP and may be explained with small fiber involvement.

• 국제물리치료학회지
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• 제5권2호
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• pp.723-729
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• 2014

The purpose of this study is to understand the relationship between female college students' stress level and premenstrual syndrome so that it can provide baseline data on how to cope with the syndrome. The study subjects are 250 female college students in Gyungbook area. This study chose 199 appropriate subjects and collected data. As per general menstrual phases, this study investigated the age when one had her first period, regularity and duration of period, and amount of bleeding. It used a measurement tool to measure stress level and premenstrual syndrome. Most of the subjects experienced their first period before the age of 13. The menstrual period was irregular with the duration of less than 7 days. 123 subjects had normal amount of bleeding. 121 subjects were experiencing high level of stress over 2.4. The correlation between the level of stress and premenstrual syndrome factors showed significant static correlation for each factor. Especially, the correlation between digestive system and response of autonomic nervous system was .996 and negative emotion and behavioral change was .635, and negative emotion and pain was .614 which were relatively high. The regression analysis of factors of premenstrual syndrome depending on the subjects' stress level indicated that response of autonomic nervous system had the biggest effect in the low stress group while behavioral change, negative emotion, pain, decreased concentration, water congestion, response of autonomic nervous system, and skin change had the biggest effect in the high stress group with statistical significance. Based on the result, it can be said that higher premenstrual stress is closely related to the premenstrual syndrome one experiences for some female college students.

• PNF and Movement
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• 제16권2호
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• pp.207-216
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• 2018

Purpose: This study aimed to investigate the fully immersive virtual reality (FIVR) program changes in the autonomic nervous system (ANS) by age according to heart rate variability (HRV). Methods: A total of 44 subjects were classified into group 1(aged 20-30), group 2(aged 40-60), and group 3(aged 70 and above). The study analyzed the HRV using a pulse wave analyzer and compared the ANS changes before and after applying the FIVR of the group. The LF, HF, RMSSD, and SDNN were measured. Fifteen minutes of virtual reality applications were applied to all subjects, and 1 min of rest was given in the middle of the session. A was used for anteroposterior comparisons of the ANS. Results: The HF, LF, RMSSD, and SDNN values were not statistically significant in all groups, but they all increased. The RMSSD value was statistically significant because it increased in group 3 (p<0.05). Those of the other two groups were not statistically significant (p<0.05). Conclusion: An FIVR program does not have a negative effect on the ANS response.

• Journal of Chest Surgery
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• 제27권1호
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• pp.9-14
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• 1994

Substance P[SP] has been known to be a peptide which may be plays a role as a neurotransmitter in central nervous system as well as peripheral autonomic nervous system. It has been reported that SP was widely distributed in the nerve of the tracheal smooth muscle and induced the muscle contraction. However, definite action mechanism of SP in the tracheal smooth muscle was not clear, yet. Thus, present experiment was performed to elucidate an effect of substance P and an action mechanism on contraction of the smooth muscle in rabbits. In order to find a neural mechanism to the effect of SP on the tracheal smooth muscle contraction, atropine sulfate, tetrodotoxin, propranol and phentolamine were administered at 10 min before the addition of SP. Otherwise,to find effect of SP antagonists on the action of SP, [D-Pro2, D-Try7,9]SP, [D-Arg1, D-Pro2, D-Trp7,9, Leu11]SP and [D-Pro4, D-Trp7,9]SP were administered as a same fashion. These following results were obtained. 1] SP induced contraction of the tracheal smooth muscle under resting condition and the contraction was increased dose-dependently. 2] Cholinergic blocker[atropine], neural blocker[tetrodotoxin] and adrenergic blocker[propranol and phentolamine] didn`t have an effect on the contractile response. 3] Three SP antagonists inhibited the contractile response. 4] Isoproterenol relaxed the contraction induced by SP. The above results suggested that SP induced contraction of the tracheal smooth muscle directly act to the smooth muscle in rabbits. The autonomic nervous system did not seem to participate in the SP action.

• Journal of Acupuncture Research
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• 제29권3호
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• pp.81-88
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• 2012

Objectives : The purpose of this study was to assess the effect of Taegeuk acupuncture on reducing mental stress by analyzing heart rate variability in Soyangin. Methods : Eight Soyangin-diagnosed women participated in this study. They were randomly divided into group A and group B. Each participant went through 3 sessions every week with 1 week of washout period in between each session. HRV was measured three times at every session; at baseline, after administering mentally stressful circumstances and after applying either one of simple rest, Soyangin Taegeuk acupuncture or Soeumin Taegeuk acupuncture. This study was designed as a crossover clinical trial. After same initial simple resting session for both groups at week 1, acupuncture for group A were executed in the order of Soyangin Taegeuk acupuncture and Soeumin Taegeuk acupuncture at week 2 and 3 respectively, with acupuncture for group B conducted in reverse order. Results : Simple rest and Soeumin Taegeuk acupuncture did not show the significant changes in response to LF(norm) and HF(norm) after stress stimuli. Soyangin Taegeuk acupuncture did, however, significantly decrease LF(norm) and increase HF(norm). Soyangin Taegeuk acupuncture, compared to Soeumin Taegeuk acupuncture, significantly stabilized autonomic nervous system. Conclusions : This study suggests that Soyangin Taegeuk acupuncture might be an effective means of stabilizing mental stress-induced imbalance of autonomic nervous system for Soyangin.