• Title/Summary/Keyword: Atypical

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Follow up of Atypical Squamous Cell Pap Smears in Iraqi Women

  • Pity, Intisar S.;Shamdeen, Maida Y.;Wais, Shawnim A.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3455-3460
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    • 2012
  • Objectives: To report the prevalence of atypical squamous cells of undetermined significance and atypical squamous cells-cannot exclude high squamous intraepithelial lesions and to determine the possible association of Pap test results with high-risk human papillomavirus and high squamous intraepithelial lesions in women from Duhok, Iraq. Design: A prospective, observational study was conducted between January 2005 and December 2011. Overall, 596 women with a cervicovaginal Pap test showing atypical squamous cells of undetermined significance and 93 atypical squamous cells-cannot exclude high squamous intraepithelial lesion for whom pathologic follow-up was available were studied. Follow-up consisted of repeat cytology, colposcopy and histology. High risk human papillomavirus DNA testing was performed on exfoliated cervical cells from 106 women, using conventional PCR after at least 36 months from the initial Pap smear. Results: Significantly high proportions of both atypical squamous cells of undetermined significance (87.9%) and atypical squamous cells-cannot exclude high squamous intraepithelial lesion (62.4%) demonstrated no significant lesion on subsequent follow up. Low squamous intraepithelial lesions were observed in 1.7% of cases of atypical squamous cells of undetermined significance and in 5.4% of atypical squamous cells-cannot exclude high squamous intraepithelial lesion. High squamous intraepithelial lesion was demonstrated in 0.8% and 16.1% respectively. In the latter there was also one case of invasive carcinoma. High-risk HPV DNA was demonstrated in 40% of atypical squamous cells of undetermined significance and 57.1% of atypical squamous cells-cannot exclude high squamous intraepithelial lesions. Conclusions: Since both atypical squamous cells of undetermined significance and atypical squamous cells-cannot exclude high squamous intraepithelial lesion identify patients who are at an increased risk for the development of high squamous intraepithelial lesions and a considerable percentage harbor high risk-HPV, both should be retained as diagnostic categories and patients warrant a diligent follow up and testing for high risk-HPV DNA. Colposcopic evaluation and biopsy, when indicated, are a must.

A Case Report on Gastritis Accompanied by Atypical Regenerative Cells Using Ortho-Cellular Nutrition Therapy (OCNT) (세포교정영양요법(OCNT)을 이용한 비정형 재생세포를 동반한 위염 사례)

  • Yeon Choi
    • CELLMED
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    • v.14 no.1
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    • pp.65.1-65.3
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    • 2024
  • Objective: Report on the improvement of gastritis accompanied by atypical regenerative cells through Ortho-Cellular Nutrition Therapy. Methods: A Korean male in his 50s suffering from gastritis accompanied by atypical regenerative cells. Results: Improvement observed in gastritis accompanied by atypical regenerative cells after the implementation of the nutrition therapy. Conclusion: Nutrition therapy can be beneficial in alleviating symptoms of gastritis accompanied by atypical regenerative cells.

ATYPICAL EMPLOYMENT IN TAIWAN'S CONSTRUCTION INDUSTRY

  • C.F. Huang;J.H. Chen;J.Z. Lin
    • International conference on construction engineering and project management
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    • 2007.03a
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    • pp.601-610
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    • 2007
  • Responding to the fierce market competition and trying to cut personnel costs, the construction industry in Taiwan is adopting atypical employment in human resource. To discover this trend, this study employed a questionnaire survey to investigate the current use of atypical employment by domestic contractors and its possible impacts on the industry. According to the 103 returned valid questionnaires, 40.8% of the respondent contractors have applied some atypical employment types in recent three years and most of them used fixed-term employment. The major reasons the contractors used atypical employees are to reduce personnel costs, to deal with business fluctuations and to streamline personnel. According to the respondents, there is no significant difference between the advantages and disadvantages of using a large number of atypical employees in the short term. However, in the long term, atypical employment is generally more disadvantageous than advantageous.

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The Effect of Atypical Anti-psychotic Agents on Obesity and Glucose Metabolism (비정형 항정신병약제가 비만과 당대사에 미치는 영향)

  • Sang Ah Lee;Suk Ju Cho;Jae Cheol Moon
    • Journal of Medicine and Life Science
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    • v.18 no.3
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    • pp.49-55
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    • 2021
  • Atypical antipsychotics are more effective than typical antipsychotics and have fewer side effects such as tardive dyskinesia and extrapyramidal symptoms; therefore, prescriptions of atypical antipsychotics are increasing. However, recently, it has been reported that atypical antipsychotics have a higher incidence of diabetes, hyperglycemia, and obesity than typical antipsychotics. Atypical antipsychotics induce obesity-inhibiting appetite-related receptors such as serotonin and dopamine. Decreased exercise due to improving psychotic symptoms, and genetic characterictics can also cause weight gain. Hyperglycemia and hypoglycemia were another metabolic problem related to treatment with atypical antipsychotics. The mechanisms of hyperglycemia were mainly related obesity, decreased anorexigenic hormones, and increased insulin resistance in multiple organs. There are also reports that genes related to diabetes have an effect on the incidence of diabetes mellitus treated with atypical antipsychotics. On the other hand, although it is not clear why hypoglycemia occurs, it documented in case reports all over the world. There are more reports of atypical antipsychotics than typical antipsychotics and these are frequently reported in Asians. Further research on the mechanism of hypoglycemia related to atypical antipsychotics is strongly recommended.

A Study on the User Behavior of Atypical Building Facilities and Spaces (비정형 건축시설물 및 공간에 대한 사용자 행동에 관한 연구)

  • Park, Hyo-Jeen;Park, Ji-Min;Lee, Hyang-Sun;Lee, Yun-Gil
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.9 no.9
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    • pp.1041-1048
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    • 2019
  • Recently, social demands on atypical buildings and building spaces are increasing, and examples of atypical buildings are easily seen in major cities around the world. This study investigates the user behaviors in the typical atypical buildings currently constructed and analyzes the characteristics of human behavior in the atypical building space. Ultimately, this study aims to develop human behavior simulation technology for reviewing residential performance of atypical building space design, and the results of this study can be used for user behavior modeling and simulation technology development. This is because it is difficult to find an investigation or analysis of what behavioral characteristics occur in the atypical building space in previous studies. This study derives the characteristics of human behavior in the atypical architectural space that has been overlooked in the existing human behavior simulation tools. In other words, the site visits and surveys typical atypical buildings to investigate user behaviors in typical spaces and other atypical buildings.

Clinical Implications of the Mitotic Index as a Predictive Factor for Malignant Transformation of Atypical Meningiomas

  • Kwon, Sae Min;Kim, Jeong Hoon;Kim, Young-Hoon;Hong, Seok Ho;Cho, Young Hyun;Kim, Chang Jin;Nam, Soo Jeong
    • Journal of Korean Neurosurgical Society
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    • v.65 no.2
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    • pp.297-306
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    • 2022
  • Objective : Intracranial atypical meningiomas have a poor prognosis and high rates of recurrence. Moreover, up to one-third of the recurrences undergo high-grade transformation into malignant meningiomas. We aimed to investigate the clinical factors that can predict the propensity of malignant transformation from atypical to anaplastic meningiomas. Methods : Between 2001 and 2018, all patients with atypical meningioma, in whom the tumors had undergone malignant transformation to anaplastic meningioma, were included. The patients' medical records documenting the diagnosis of atypical meningioma prior to malignant transformation were reviewed to identify the predictors of transformation. The control group comprised 56 patients with atypical meningiomas who were first diagnosed between January 2017 and December 2018 and had no malignant transformation. Results : Nine patients in whom the atypical meningiomas underwent malignant transformation were included. The median time interval from diagnosis of atypical meningioma to malignant transformation was 19 months (range, 7-78). The study group showed a significant difference in heterogeneous enhancement (77.8% vs. 33.9%), bone invasion (55.6% vs. 12.5%), mitotic index (MI; 14.8±4.9 vs. 3.5±3.9), and Ki-67 index (20.7±13.9 vs. 9.5±7.1) compared with the control group. In multivariate analysis, increased MI (odds ratio, 1.436; 95% confidence interval, 1.127-1.900; p=0.004) was the only significant factor for predicting malignant transformation. Conclusion : An increased MI within atypical meningiomas might be used as a predictor of malignant transformation. Tumors at high risk for malignant transformation might require more attentive surveillance and management than other atypical meningiomas.

A Study on Characteristics of the Visual Perception of Atypical and typical Space in Houses (비정형과 정형 주거공간의 시지각적 특성에 관한 연구)

  • Lee, Sang-Hwa
    • Journal of the Korean housing association
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    • v.18 no.3
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    • pp.81-89
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    • 2007
  • This study is aimed at understanding objectively on the visual perception of atypical space and form in contemporary architecture. It is accomplished to compose the various form and the atypical space in contemporary architecture, which by means of applying digital technology to architecture is able to materialize complicated form and space. Therefore this the sis is needed to understand user's senses and affects in atypical space and form. Atypical space is able to interpret geometrically and analyze quantitatively into visual perception. This analysis is applied to Isovist used as quantitative analysis recently, and physical analysis of space used as quantitative analysis defined to vertical elements, which is analysed comparatively to visual perception in observer's point and characteristics in spatial elements. Examples are selected to four examples represented to typical and atypical space in contemporary houses. As examples are analysed to visual perception of spatial character, this study is intended to understand to spatial character in aspects of spatial composition and observer's visual perception. In results of perceptive analysis on four spatial examples, Atypical spaces are composed of changeable spatiality, which are composed changeably of the relational method with adjacent spaces. Also, typical spaces are composed monotonously of spatiality and relational method on control of the length in boundary plane and openness.

Fine Needle Aspiration Cytology of Atypical Carcinoid Tumor of the Lung - 2 Cases Report - (폐의 비정형 유암종의 세침흡인 세포학적 소견 - 2예 보고 -)

  • Lee, Youn-Soo;Park, Gyeong-Sin;Choi, Young-Jin;Kang, Seok-Jin;Kim, Byung-Kee;Shim, Sang-In
    • The Korean Journal of Cytopathology
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    • v.8 no.1
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    • pp.76-82
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    • 1997
  • Two cases of pulmonary atypical carcinoid tumor were diagnosed by fine needle aspiration cytology. Although the cytologic features of atypical carcinoid tumor have been relatively well described, it is easy to confuse atypical carcinoid tumor with typical carcinoid tumor, small cell carcinoma and adenocarcinoma of the lung. Atypical carcinoid tumor has been recognized as a distinct variant of pulmonary neuroendocrine carcinoma, with characteristic histopathologic and clinical features that separate it from both carcinoid and small cell carelnoma. The distinction of atypical carcinoid tumor from small cell carcinoma has important prognostic and therapeutic implications. The cytologic characteristics of atypical carcinoid tumor included polygonal to fusiform cells with a variable amount of lacy cytoplasm, oval nuclei with coarsely dispersed chromatin and frequent nucleoli, and mild pleomorphism. The malignant cells were arranged either in acinus-like clusterg or in epithelial sheets.

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Treatment of Atypical Facial Pain with Stellate Ganglion Block (비정형 안면통에서의 성상신경절 차단 치료)

  • Jeon, Young Hoon;Kim, Ji Hyun
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.14 no.3
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    • pp.173-175
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    • 2014
  • Atypical facial pain is loosely used term to describe some chronic facial pain when the symptoms do not exactly and entirely fit one diagnostic criteria. In many cases of pain disorders, sympathetic system is involved, such as in conditions which symptoms mimic post-herpetic neuralgia or complex regional pain syndrome. We report a case of a patient with atypical facial pain following the reduction of temporomanidbular joint dislocation. The atypical pain which was resistant to analgesic medication was successfully managed with stellate ganglion block. Therefore we suggest that stellate ganglion block can be an effective treatment method for controlling atypical facial pain.

Pharmacotherapy in Child and Adolescent Psychiatric Field: Atypical Antipsychotics (소아청소년정신과 영역의 약물치료 : 비전형항정신병약물)

  • Yoo, Han-Ik K.;Paik, Kyoung-Won
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.19 no.2
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    • pp.89-103
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    • 2008
  • Although the scientific evidence is not entirely supportive, atypical antipsychotics have been used widely for the treatment of children and adolescents with mental illnesses as alternatives to typical antipsychotics which have more serious unwanted adverse effects than atypical neuroleptics. On the basis of clinical experiences and research data, atypical antipsychotics have been prescribed for adolescents with schizophrenia, manic or mixed episodes of bipolar disorders, tic disorders, aberrant behaviors in pervasive developmental disorders, and impulsive or violent behaviors in disruptive behavior disorders. Due to their efficacy and relatively more tolerable side effects, the use of atypical antipsychotics has become increasingly popular in child and adolescent psychiatry. However, we should pay attention to the limitations associated with short-term clinical experiences and the lack of well-designed controlled studies, especially in terms of adverse effects including those involving metabolic processes.

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