• 제목/요약/키워드: Attachment material

검색결과 267건 처리시간 0.024초

Osteogenic differentiation of bone marrow derived stem cells in gelatin-hydroxyapatite nanocomposite

  • Jeon, Hyun-Jun;Hwang, Young-Sup;Kim, Uk-Kyu;Hwang, Dae-Seok;Lee, Kwang-Ho;Chang, Myung-Cheol
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제35권1호
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    • pp.7-12
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    • 2009
  • Purpose: Gelatin-hydroxyapatite nanocomposite is similar to inorganic nanostructure of bone. To make a scaffold with osteoinductivity, bone marrow derived stem cells from rabbit femur were impinged into the nanocomposite. This vitro study was to test osteogenic differentiation of the stem cells in the nanocomposite, which was made by authors. Material & Methods: Gel-HA nanocomposite with 10g of HA, 3 g of Gel has been made by co-precipitation process. Bone marrow was obtained from femur of New Zealand White rabbits and osteogenic differentiation was induced by culturing of the BMSCs in an osteogenic medium. The BMSCs were seeded into the Gel-HA nanocomposite scaffold using a stirring seeding method. The scaffolds with the cells were examined by scanning electron microscopy (SEM), colorimetry assay, biochemical assay with alkaline phosphatase (ALP) diagnostic kit, osteocalcin ELISA kit. Results: Gel-HA nanocomposite scaffolds were fabricated with relatively homogenous microscale pores ($20-40{\mu}m$). The BMSCs were obtained from bone marrow of rabbit femurs and confirmed with flow cytometry, Alizarin red staining. Attachment and proliferation of BMSCs in Gel-HA nanocomposite scaffold could be identified by SEM, ALP activity and osteocalcin content of BMSCs. Conclusion: The Gel-HA nanocomposite scaffold with micropores could be fabricated and could support BMSCs seeding, osteogenic differentiation.

섬유기반의 웨어러블 디바이스용 유연소재 및 플랫폼 개발동향 분석 -국내외 특허분석을 중심으로- (Analysis on the development trend of flexible materials and platforms for wearable devices based on fiber - Based on domestic & international patent data -)

  • 한현정;장명진;이용성
    • 한국의상디자인학회지
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    • 제22권1호
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    • pp.33-44
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    • 2020
  • The purpose of this study is to guide the research direction for securing the competitiveness of the textile industry by analyzing the trends of patent technology development for flexible materials and platform technologies of domestic and overseas textiles used for wearable devices. The study is based on patents from Korea (KIPO), USA (USPTO), Japan (JPO), Europe (EPO), PCT (WO), and China (SIPO), which were registered as of December 31, 2017. The analysis utilized 3,643 patents acquired from the WINTELIPS search DB. The technology classification system for patent analysis was divided into evangelist-based textile technology developments: human body (AA), fiber attachment patch development (AB), and service platform development (AC). The analysis findings are as follows: 1. The development of flexible materials and platform technologies for textile-based wearable devices has increased since 2000. In particular, China (SIPO) had the most patents. 2. In China, Japan, and Korea, most patent applicants are applied for by natives, but the US has a high proportion of foreigners applying for patents. 3. As for the amount of development of the evangelist-based textile technology (AA) was the most common with 1,203 (33%) cases. As a result of the above IP historical analysis, it can be seen that as a result of the global competition, domestic companies need to acquire IRP and standard technology, and promote commercialization by applying their products to smart wearables devices and other products.

Clinical evaluation of a biphasic calcium phosphate grafting material in the treatment of human periodontal intrabony defects

  • Lee, Min-Jae;Kim, Byung-Ock;Yu, Sang-Joun
    • Journal of Periodontal and Implant Science
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    • 제42권4호
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    • pp.127-135
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    • 2012
  • Purpose: The aim of this study was to compare the clinical outcome of open flap debridement (OFD) with a biphasic calcium phosphate (BCP) graft to that of OFD without BCP graft for the treatment of intrabony periodontal defects (IBDs). Methods: The study included 25 subjects that had at least one intrabony defect of 2- or 3-wall morphology and an intrabony component ${\geq}4$ mm as detected radiographically. Subjects were randomly assigned to treatment with (BCP group, n=14) or without BCP (OFD group, n=11). Clinical parameters were recorded at baseline and 6 months after surgery and included the plaque index, gingival index, probing depth (PD), clinical attachment level (CAL), and gingival recession (REC). A stringent plaque control regimen was enforced for all of the patients during the 6-month observation period. Results: In all of the treatment groups, significant PD reductions and CAL gains occurred during the study period (P<0.01). At 6 months, patients in the BCP group exhibited a mean PD reduction of $3.7{\pm}1.2$ mm and a mean CAL gain of $3.0{\pm}1.1$ mm compared to the baseline. Corresponding values for the patients treated with OFD were $2.5{\pm}0.8$ mm and $1.4{\pm}1.0$ mm, respectively. Compared to OFD group, the additional CAL gain was significantly greater in the patients in BCP group (P=0.028). The additional PD reduction was significant for the BCP group (P=0.048). The REC showed a significant increase in both groups, and the amount of recession was significantly smaller in the BCP group than OFD group (P=0.023). In radiographic evaluation, the height of the bone fill in the BCP group was significantly greater than OFD group. Conclusions: The clinical benefits of BCP found in this study indicate that BCP may be an appropriate alternative to conventional graft materials.

페이스트를 이용한 탄소나노튜브의 수직배양법 연구 (Process Development of Aligning Carbon Nanotube from the Paste)

  • 이재걸;문주호;이동구
    • 한국세라믹학회지
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    • 제39권5호
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    • pp.467-472
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    • 2002
  • 다이아몬드 연마 필름(diamond lapping film)으로 긴 탄소나노튜브를 절단하고 이를 Scanning Electron Microscope(SEM)으로 관찰했다. 절단된 탄소나노튜브를 ${\alpha}$-terpineol을 용매로 ethyl cellulose를 바인더로 사용하여 제조한 페이스트를 스크린 프린팅과 주사 사출법으로 유리 기판에 도포하였다. 스크린 프린팅으로 인쇄된 선에 존재하는 절단된 탄소나노튜브를 기판에 대해 수직 배향을 시키기 위하여 사포, 다이아몬드 연마 필름을 사용하여 마찰시키거나 접착성이 있는 테이프를 이용하여 접촉시켰다가 분리 하는 방법을 시도하였다. SEM으로 탄소나노튜브의 배향 특성을 관찰한 결과 주사 사출법과 스크린 프린팅 후 다이아몬드 연마 필름을 사용하여 후처리하는 간편한 방법으로 탄소나노튜브의 우수한 수직배양이 이루어짐을 알 수 있었다.

참전복, Haliotis discus hannai 표식개체의 실내사육 및 방류효과 (Effects of Stocking and Laboratory Rearing in Abalone, Haliotis discus hannai by Tagging)

  • 강경호;위종환;김광수
    • 한국양식학회지
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    • 제9권2호
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    • pp.109-115
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    • 1996
  • 우리나라 연안성에서 가장 중요한 양식대상종의 하나인 참전복의 표식 방류효과에 관한 조사는 보고된 바 없는 실정이다. 따라서 본 연구는 우리 배양장에서 자체 생산된 참전복의 표지 방법별 효과를 검토하고, 방류효과를 구명함으로서 연안 자원의 증강을 도모 하고자 1994년 11월 10일 부터 1995년 3월 30일까지 조사한 결과를 요약하면 다음과 같다. 1. 참전복의 표지 및 표시 방법별 효과는 Al-teco에 의한 표지 부착이 가장 좋았다. 2. 실내 사육에 의한 표지의 탈락 및 폐사율은 각각 $6.7\%$$8.3\%$였고, 표지에 의한 폐사는 없었다. 3. 실내 사육 및 방류한 표지 개체는 실험 개시시 각구 공히 평균각장 및 전중량이 1.0 cm, 0.092 g 이던 것이 실험종료시에는 각각 1.80cm, 0.74 g, 1.68 cm, 0.68 g으로 성장하였다. 4. 재포된 모든 개체의 분포 중심 수심은 2.6m 였다. 재포된 모든 개체의 평균 이동 거리는 2.6m 였다. 6. 어획사망계수, 자연사망계수 및 전사망계수의 추정치는 각각 0.0195, 0.4652, 0.4847였다.

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Analysis of osteogenic potential on 3mol% yttria-stabilized tetragonal zirconia polycrystals and two different niobium oxide containing zirconia ceramics

  • Hein, Aung Thu;Cho, Young-Dan;Jo, Ye-Hyeon;Kim, Dae-Joon;Han, Jung-Suk
    • The Journal of Advanced Prosthodontics
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    • 제10권2호
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    • pp.147-154
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    • 2018
  • PURPOSE. This study was performed to evaluate the osteogenic potential of 3mol% yttria-stabilized tetragonal zirconia polycrystals (3Y-TZP) and niobium oxide containing Y-TZPs with specific ratios, new (Y,Nb)-TZPs, namely YN4533 and YN4533/Al20 discs. MATERIALS AND METHODS. 3Y-TZP, YN4533 and YN4533/Al20 discs (15 mm diameter and 1 mm thickness) were prepared and their average surface roughness ($R_a$) and surface topography were analyzed using 3-D confocal laser microscope (CLSM) and scanning electron microscope (SEM). Mouse pre-osteoblast MC3T3-E1 cells were seeded onto all zirconia discs and evaluated with regard to cell attachment and morphology by (CLSM), cell proliferation by PicoGreen assay, and cell differentiation by Reverse-Transcription PCR and Quantitative Real-Time PCR, and alkaline phosphatase (Alp) staining. RESULTS. The cellular morphology of MC3T3-E1 pre-osteoblasts was more stretched on a smooth surface than on a rough surface, regardless of the material. Cellular proliferation was higher on smooth surfaces, but there were no significant differences between 3Y-TZP, YN4533, and YN4533/Al20. Osteoblast differentiation patterns on YN4533 and YN4533/Al20 were similar to or slightly higher than seen in 3Y-TZP. Although there were no significant differences in bone marker gene expression (alkaline phosphatase and osteocalcin), Alp staining indicated better osteoblast differentiation on YN4533 and YN4533/Al20 compared to 3Y-TZP. CONCLUSION. Based on these results, niobium oxide containing Y-TZPs have comparable osteogenic potential to 3Y-TZP and are expected to be suitable alternative ceramics dental implant materials to titanium for aesthetically important areas.

345 kV 케이블 종단접속부에서의 폭발사고 원인분석 (The cause analysis of explosion on junction termination of 345kV cable)

  • 송길목;방선배;김종민;김영석;최명일
    • 한국화재조사학회학술대회
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    • 한국화재조사학회 2011년도 제20회 추계학술대회
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    • pp.63-79
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    • 2010
  • 345 kV 케이블의 종단접속부에서는 다수의 아크흔적이 발견된다. 재료분석에 의하면 케이블은 양호한 것으로 판정된다. 제조 및 설계상의 문제점은 없는 것으로 판단된다. 시공상의 결함요인 중 절연유 레벨이 낮은 것으로 추정되었다. XLPE에서는 다수의 Arc trace가 나타난 것을 확인하였다. 그러나 Soots mark가 없고, Yellow band 확인되지 않았으며, 방사형의 spider leg와 연결되지 않은 아크흔적이 없다. 이견사항으로는 XLPE의 내부에 보이드, 이물질 또는 돌기로 의심되는 것은 발견되지 않았다. 따라서 XLPE에서 이물질의 부착에 의한 절연파괴인 것으로 판단된다.

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해외 소셜 미디어에 나타난 시니어 패션과 심리적 특성 (A Study on Seniors' Fashion and Psychological Characteristics Shown at Overseas Social Media)

  • 최정희;이경희
    • 한국의류산업학회지
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    • 제18권6호
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    • pp.858-868
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    • 2016
  • This study aims to examine the formative characteristics of seniors' fashion in overseas social media, and look into the psychological characteristics of seniors by analyzing the emotions and the characteristics of psychological mechanism in seniors' fashion. The study methods include statistical analysis and content analysis for literary study and data analysis. For data analysis, statistical and content analyses were conducted to analyze 992 data collected from Advanced style, Facebook, and Instagram for 4 years from 2013 to 2016. In formative features shown at overseas social media, circle and square silhouette, achromatic color and warm color, showy tone color, soft material, horizontal details, plain and natural patterns, cap and sunglasses production, and sophisticated elegance styles appeared high. The emotional characteristics in senior's fashion had a silhouette that expressed stability, color that expressed passion, love, happiness, joy, hope and comfort. Materials were expressed by the emotions of dependence and attachment, details were expressed by stable, maternal, calm, comfortable and harmonious emotions. Patterns were expressed by the images of beauty, love, fruit and psychological stability. Accessories were expressed by young and characterful images. Style expressed the emotions of trust, pride, longing, intoxication and ecstasy. The characteristics of psychological mechanism used such shapes and patterns as flower, heart and lips to symbolize the emotions of love, humor, and fun. Young and trendy fashion were expressed in compensation for aging. Kitsch and kidult style was expressed by regression. Elegance fashion was expressed by the sublimation of pride, trust and intoxication.

시료용액의 특성에 따른 고정화된 단일벽 탄소나노튜브의 전기적 거동 (Electrical Property of Immobilized SWNTs Bundle as Bridge between Electrodes in Nanobiosensor Depending on Solvent Characteristics)

  • 이진영;조재훈;박철환
    • Korean Chemical Engineering Research
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    • 제55권1호
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    • pp.115-120
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    • 2017
  • 현재 세계적인 이슈가 되고 있는 나노과학과 기술은 탄소나노튜브(CNTs)를 기반으로 한 바이오센서 성능 향상에 주력하고 있다. 다양한 기능성을 가진 CNTs는 높은 안정성과 바이오 수용체와 같은 생체물질과의 높은 적합성으로 이를 이용한 바이오 전극 기술에 힘입어 의학, 식품 및 환경에서 이슈가 되는 물질들을 검출하기 위한 산업적 응용 연구가 주목받고 있다. 본 연구에서는 이러한 CNTs를 이용한 전기화학적 바이오센서에 있어서 시료가 액체 상태로 검출이 예상되는데 그 시료의 화학적 특성에 따른 금 전극 사이에 고정화된 CNTs의 전자전달현상을 조사하였다. 그 결과, 시료가 극성인 경우와 무극성인 경우 고정화된 CNTs의 전자전달 현상이 다르게 나타났으며, 극성의 세기가 증가할수록 전자의 이동에 방해를 받는 것으로 확인되었다. 이는 CNTs의 양끝에 존재하는 극성 작용기와의 상호작용에 의한 것으로서 센서 디바이스 전체를 시료 용액에 침투시켜 전자이동을 관찰한 결과와 달리 안정적으로 저항값을 나타내는 것으로 확인되었다. 향후 민감도가 높은 CNTs 기반 나노바이오센서 개발 시 시료의 효과적인 전처리 공정에서 이러한 용매의 극성을 고려한 최적화 연구가 필요하다.

폴리아닐린/나일론 6 복합직물의 전기 전도도 향상 연구 (Conductivity Improvement of Polyaniline/Nylon 6 Fabrics)

  • 오경화;성재환;김성훈
    • 폴리머
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    • 제24권5호
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    • pp.673-681
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    • 2000
  • 플라즈마 처리가 나일론 6 직물의 표면 특성과 폴리아닐린/나일론 6 복합직물의 전도도에 미치는 영향을 연구하였다. 산소 플라즈마로 처리한 나일론 6 직물의 표면을 XPS 분석을 통해 확인한 결과 C-O, C-OH 등의 관능기가 도입되었으며, 이는 직물과 폴리아닐린의 결합력을 향상시켜 전기 전도도와 폴리아닐린 부착량을 증가시켰다. 또한 산소 플라즈마로 처리된 폴리아닐린/나일론 6 복합직물은 세탁과 마모에서도 우수한 안정성을 나타내었다. 초음파 처리는 매질에 발생된 cavitation과 진동에 의해 직물 내부로 아닐린을 확산시키는데 효과적이었으며, 이는 폴리아닐린/나일론 6 복합직물의 전기 전도도를 크게 향상시켰다. 아닐린의 농도와 중합욕에 침지 휫수가 증가함에 따라 전기 전도도와 복합직물의 형태안정성에 대한 영향을 살펴보았는데, 단량체 농도는 0.5M 까지는 증가함에 따라 전도도가 향상되었으며, 침지 횟수가 증가함에 따라서도 전도도가 향상되었다.

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