• Title/Summary/Keyword: Atopic dermatitis severity

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Severity of Atopic Dermatitis and Associated Factors in Korean Adolescents by Sex (성별에 따른 한국 청소년의 아토피 피부염 심각성과 영향요인)

  • Yi, Yunjeong;Hyun, Sook Jung;Lee, Jinhwa;An, Ji Yeon
    • Journal of the Korean Society of School Health
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    • v.30 no.2
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    • pp.164-173
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    • 2017
  • Purpose: Despite the high incidence, the incidence of atopic dermatitis among adolescents has been continuously increasing. The study was conducted to examine the severity of atopic dermatitis among middle school students and to identify the factors affecting the severity. Methods: The data used in the analysis are from 2015 Youth Health Behavior Online Survey. Complex sample analysis was conducted to analyze the severity of atopic dermatitis which was defined by the treatment experience of atopic dermatitis and the number of absent days due to the disease as its criteria. Binary logistic regression of the factors affecting the severity of atopic dermatitis by gender was done. Results: The severity of atopic dermatitis was high in male students who were in a lower grade (freshmen), who smoked, or who consumed soft drinks at least once a week, while in female students who were in a lower grade (freshmen, sophomore), who consumed alcohol, who consumed highly caffeinated drinks at least once a week or who consumed sweet drinks at least once a week. The severity of atopic dermatitis was lower in female students who lived in big cities or medium/small sized cities or engaged in physical activities less than three times a week. Conclusion: For atopic dermatitis among middle school students, the importance of dietary management should be considered. This indicates that families, schools, and communities have their own responsibilities and efforts to relieve the symptoms of the atopic dermatitis.

Two Cases of Atopic Dermatitis (아토피 피부염 치험 2례)

  • Shim, Eun-Ki;An, Chan-Gn;Du, In-Sun;Hwang, Chung-Yeon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.18 no.2
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    • pp.109-117
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    • 2005
  • Atopic Dermatitis is chronic eczematous dermatosis which is related strongly to a family history of atopic disease and hereditary disposition. Its threshold of itching is low so that severe itching occurs and causes secondary eczema. The purpose of this study was to estimate the efficiency of oriental medical treatment and management on atopic Dermatitis. We studied 2 patients who visited Wonkwang University Kwangju Oriental Hospital Dept. of Dermatol. with atopic dermatitis from April 2004 to February 2005. We treated him with herb-medication, acupuncture, negative therapy, full spectrum visible ray therapy(by carbon arc). We used the ADSI(Atopic Dermatitis Severity Index) to assess the severity of atopic dermatitis. The grade of the severity of atopic dermatitis was lower only by the traditional chinese medical treatments and management. Considering the above result, more study is needed the factors of increasing severity of atopic dermatitis, and the clinical interchange or atopic Dermatitis between oriental medicine and western medicine.

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Improvement of Post-inflammatory Hyperpigmentation, Subsequent to Cold Atmospheric Plasma Treatment, in a Patient with Atopic Dermatitis

  • Lee, Mi Young;Won, Chong Hyun;Kim, Young Jae
    • Medical Lasers
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    • v.9 no.2
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    • pp.187-189
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    • 2020
  • Cold atmospheric plasma (CAP) is a material that generates free radicals through the ionization of air. Despite the application in various medical fields, the efficacy and safety of CAP on post-inflammatory hyperpigmentation due to atopic dermatitis have not been reported. Herein, we report the improvement in post-inflammatory hyperpigmentation of atopic dermatitis, after CAP treatment of three sessions weekly, 10 minutes per session. We examined the clinical severity indexes before and after treatment, including the Investigator's Global Assessment, modified Atopic Dermatitis Antecubital Severity, Eczema Area and Severity Index, and pruritus visual analogue scores. Our results indicate that CAP alleviates the post-inflammatory hyperpigmentation and clinical severity of atopic dermatitis, and effectively improves the atopic skin lesion without severe safety issues. We believe that the previously reported anti-bacterial effects and production of interleukin-6 after CAP treatment are probably responsible for the underlying mechanisms leading to clinical improvement.

Associated Factors with Severity of Atopic Dermatitis in Children (영유아의 아토피피부염 중증도 관련 요인 연구)

  • Lee, Jae-Sun;Jo, Sun-Mi;Lee, Hee-Chul;Ahn, Kang-Mo;Chung, Sang-Jin
    • Korean Journal of Community Nutrition
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    • v.15 no.6
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    • pp.776-782
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    • 2010
  • The prevalence of atopic dermatitis (AD) has increased over the past decades. A variety of factors are related to the development of atopic dermatitis, including genetics and environmental factors. The purpose of the study was to examine factors associated with severity of atopic dermatitis in 104 children aged 6-60 months. To investigate the association between severity and other factors children were divided into two groups, mild (n = 62) and severe (n = 42) groups, based on SCORAD index which measures the severity of atopic dermatitis. Results showed that family history, family's smoking, period of having AD and the levels of the serum total IgE were significantly higher in severe group. More than 6 months of breastfeeding and weaning after 6 month were not associated with severity of AD, but the number of food eliminated was associated with severity. Only vitamin C intake was significantly different by severity after adjusting for energy intake, family history, family’s smoking and period of having AD (p = 0.033). There was no association between the severity of atopic dermatitis and growth of children. This study concluded that the severity of atopic dermatitis was associated with family history, family’s smoking, period of having AD, children's serum total IgE, and vitamin C intakes. The result of this study should provide the significant information for better management of AD.

A Comparative Study of Family Management Style According to Severity of Childhood Atopic Dermatitis (아토피피부염 환아의 중증도에 따른 가족관리방식의 비교)

  • Son, Hae Kyoung;Kim, Hee-Soon
    • Child Health Nursing Research
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    • v.22 no.4
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    • pp.309-316
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    • 2016
  • Purpose: This study of secondary analysis aims to compare family management style according to severity in children with atopic dermatitis. Methods: A convenience sample of 109 Korean mothers caring for a child with atopic dermatitis, were recruited from the pediatric departments of two general hospitals in Seoul. Data were collected from November 1, 2015 to February 28, 2016. A structured self-report questionnaire was used. Data were analyzed using descriptive statistics, correlation analysis, and one-way ANOVA with IBM SPSS Version 22.0. Results: For family management style, condition management effort, family life difficulty, and view of condition impact were significantly different according to the severity of the atopic dermatitis in these children. Conclusion: The findings indicate that family management strategies to enhance care of children with atopic dermatitis as well as members of the family should include these significant variables in a family-centered approach.

A study on the Severity Scoring Systems of Atopic Dermatitis ; Comparision, Analysis and Establishment (아토피 피부염의 평가방법에 대한 연구 : 비교 분석 및 설립)

  • 윤화정;윤정원;윤소원;고우신
    • The Journal of Korean Medicine
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    • v.23 no.4
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    • pp.15-26
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    • 2002
  • There is much confusion in the field of atopic dermatitis (AD) regarding how to best measuredisease severity objectively. Therefore, we aimed to establish a new adequate scoring system for AD, that should be based on comparisonand analysis of various scoring systems. We report as follows. Methods: We searched for data relating to severity scoring systems for atopic dermatitis in Entrez PubMed From 1990 to 2001 Results and Conclusions: 1. Properties of severity scoring systems were validity, reliability, sensitivity of change and ease of use. 2. The essential items of severity scoring systems were extent. intensity and subjective symptoms. 3. The surface extent of the lesion was evaluated by the percentage of involvement of each of 10 areas. 4. The criteria of severity were divided into intensity and subjective symptoms. Intensity items are erythema, papulation, lichenification, oozing, dryness, excoriations, and pigmentation. The subjective symptom is pruritus, evaluated according to sleep loss. 5. The significant items of severity scoring system were symptomsrather than areas. As it were, we assumed extent accounted for around 30% of each total score, with intensity and subjective symptoms representing 70%.

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The Correlation between SCORAD Index and Serum Total IgE or Eosinophil Count in Individual Patients of Atopic Dermatitis (아토피피부염 환자에서 중증도 변화에 따른 SCORAD index와 혈청 총 IgE 및 호산구 수의 상관관계)

  • Kwak, Jae-Young;Kim, Min-Hee;Kang, Min-Seo;Choi, In-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.31 no.1
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    • pp.42-51
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    • 2018
  • Objectives : This study was aimed to evaluate the correlation between changes in disease severity and serum total IgE or eosinophil count in individual patients of atopic dermatitis depending on the change of severity. Methods : We performed a retrospective chart review of 8 cases of atopic dermatitis who underwent blood tests more than five times. Disease severity was assessed by objective SCORing of Atopic Dermatitis index (OSI). Blood tests include serum total IgE, eosinophil counts, aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN) and serum creatinine (SCr). In each subject, on the day that the blood test was performed, OSI was also assesed by a same physician. Correlation between OSI and total IgE or eosinophil count was analysed by nonparametric correlation analysis. Results : There was a statistically significant positive correlation between OSI and total IgE in three cases and a positive correlation between OSI and eosinophil count in two cases. In other three cases, there were no significant correlation. There were no cases that OSI correlated with total IgE and eosinophil count at the same time. In all cases, AST, ALT, BUN and SCr were stable. Conclusions : We suggest that total IgE and eosinophil count may reflect the severity of atopic dermatitis differently in individual patients. We also suggest that total IgE and eosinophil counts may be used as biomarkers to predict the severity of atopic dermatitis in some patients depending on the underlying pathology.

A study on the Severity Scoring Systems of Atopic Dermatitis ; comparison, Analysis and Establishment of childhood patients in Oriental Medicine (아토피 피부염의 중증도 평가방법에 대한 제언 ; 비교 분석 및 소아 환자의 평가방법에 대한 설립)

  • Seo, Jung-Min;Kim, Sang-Chan;Hwang, Sun-Yi;Hwang, Bo-Min;Jee, Seon Young;Lee, Sang-Gon;Baek, Jung-Han
    • The Journal of Pediatrics of Korean Medicine
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    • v.20 no.1
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    • pp.1-14
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    • 2006
  • Objective : As prevalence of atopic dermatitis(AD) rises and medicine of atopic dematitis develops, the methods of measurement for atopic dermatitis have developed. Therefore, we aimed to establish a new sconring system in oriental medicine for a childhood atopic dematitis, by comparison, analysis of various sconing systems. Method : We searched for the data related to severity sconing systems of atopic dermatitis in Entrez PubMed on abroad thesis and KISS(Korenstdued Information Service System) on domestic thesis from 1990 to 2005. Result : Severity sconing systems for atopic dermatitis satisfy validity, reliability, sensitivity of change and verification of this. The essential items of severity sconing systems are extent, intensity and subjective symptoms. The lesion is divided into 9 areas(head and neck, upper limbs, elbow, hands, trunk, hip and inguinal, lower limbs, knee, feet). The items of intensity are erythema, oedema and induration and papulation, oozing and weeping and erosion, excorition, scaling, lichenification. The subjective symptom is pruritis, evaluated according to sleep loss and obstruction of play and study. The extent and intensity is evaluated in combination. We suggested that extent and intensity occupied for 70% and subject symptoms accounted for 30% of total score.

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Three Cases of Chronic Adult Atopic Dermatitis (만성 성인형 아토피 피부염의 한방 치험 3례)

  • Ku, Young-Hui;Choi, In-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.15 no.1
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    • pp.140-150
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    • 2002
  • Introduction: Atopic dermatitis is chronic eczematous dermatosis which is related strongly to a family history of atopic disease and hereditary disposition. Its threshold of itching is low so that severe itching occurs and causes secondary eczema. Adult atopic dermatitis has mostly severe symptoms and progresses to chronic relapsing. Objective: The purpose of this study was to estimate the efficacy of oriental medical treatment and management on chronic adult atopic dermatitis. Subject: We studied 3 patients who visited Dongguk University Gangnam Oriental Hospital Dept. of Dermatol. with chronic adult atopic dermatitis from August 2001 to April 2002 and were observed for over 4 months. Methods: We treated them with herb-medication, acupuncture, negative therapy, aroma therapy, full spectrum visible ray therapy(by carbon arc) and external application(Jaun-go). We used the SCORAD index to assess the severity of atopic dermatitis. Results: There were 3 patients with chronic adult atopic dermatitis we could check for over 4 months by clinical scoring using the SCORAD system. 1. The grades of the severity of atopic dermatitis were lower only by the oriental medical treatments and management. 2. Intensities of relapse cases were lower then before the oriental medical treatments. 3. The secondary treatment term for relapse cases was shorter then the first treatment term after oriental remedies were used. Conclusion: Considering the above results, more study is needed on the chronic relapse cases with adult atopic dermatitis, the factors of increasing seventy of adult atopic dermatitis, the prognostic factors of adult atopic dermatitis, and the clinical interchange of chronic adult atopic dermatitis between oriental medicine and western medicine.

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The Correlation between Atopic Dermatitis Severity and Heart Rate Variability (아토피피부염의 중증도와 심박변이도의 상관성 연구)

  • Yu, Seung-Min;Yoo, Seung-Yeon;Kim, Min-Hee;Yun, Young-Hee;Choi, In-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.24 no.3
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    • pp.65-73
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    • 2011
  • Background : There are findings indicating that the autonomic nervous system (ANS) is affected negatively in atopic dermatitis (AD). Heart rate variability (HRV) is a tool to examine ANS. But, studies investigation the relationship between AD and HRV is rare. Objective : The aim of this study was to investigate the correlation between atopic dermatitis severity and HRV and to find out the role of ANS in AD. Methods : Retrospective chart review was performed. The Severity Scoring Atopic Dermatitis (SCORAD) index and HRV parameter was investigated and analyzed. Results : There were 55 patients (25males and 30 females) who met the criteria. Objective SCORAD had significant positive correlation with HRT and Subjective SCORAD had significant negative correlation with SDNN, TP and VLF. Intensity item of SCORAD index had negative correlation with most HRV parameters, but TP, LF and LF/HF ratio had significant positive correlation with dryness. Conclusion : This study supports the concept that atopic dermatitis is a stress-responsive disorder and involves autonomic nervous system dysfunction.