• Medical Lasers
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• v.9 no.2
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• pp.187-189
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• 2020

Cold atmospheric plasma (CAP) is a material that generates free radicals through the ionization of air. Despite the application in various medical fields, the efficacy and safety of CAP on post-inflammatory hyperpigmentation due to atopic dermatitis have not been reported. Herein, we report the improvement in post-inflammatory hyperpigmentation of atopic dermatitis, after CAP treatment of three sessions weekly, 10 minutes per session. We examined the clinical severity indexes before and after treatment, including the Investigator's Global Assessment, modified Atopic Dermatitis Antecubital Severity, Eczema Area and Severity Index, and pruritus visual analogue scores. Our results indicate that CAP alleviates the post-inflammatory hyperpigmentation and clinical severity of atopic dermatitis, and effectively improves the atopic skin lesion without severe safety issues. We believe that the previously reported anti-bacterial effects and production of interleukin-6 after CAP treatment are probably responsible for the underlying mechanisms leading to clinical improvement.

• Biomolecules & Therapeutics
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• v.31 no.5
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• pp.496-514
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• 2023

Cold atmospheric plasma (CAP), a redox modulation tool, is capable of inhibiting a wide spectrum of cancers and has thus been proposed as an emerging onco-therapy. However, with incremental successes consecutively reported on the anticancer efficacy of CAP, no consensus has been made on the types of tumours sensitive to CAP due to the different intrinsic characteristics of the cells and the heterogeneous design of CAP devices and their parameter configurations. These factors have substantially hindered the clinical use of CAP as an oncotherapy. It is thus imperative to clarify the tumour types responsive to CAP, the experimental models available for CAP-associated investigations, CAP administration strategies and the mechanisms by which CAP exerts its anticancer effects with the aim of identifying important yet less studied areas to accelerate the process of translating CAP into clinical use and fostering the field of plasma oncology.

• Atmosphere
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• v.26 no.4
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• pp.635-647
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• 2016

The effects of sea surface temperature (SST) gradient induced by the previous typhoon on the following typhoon motion over East Asia have been investigated using Weather Research and Forecasting (WRF) model for the previous Typhoon Bolaven (1215) and following Typhoon Tembin (1214). It was observed that Typhoon Bolaven remarkably reduced SST by about $7^{\circ}C$ at Yellow Sea buoy (YSbuoy). Using the WRF experiments for the imposed cold wake over West of Tembin (WT) and over East of Tembin (ET), this study demonstrates that the effects of eastward SST gradient including cold wake over WT is much significant rather than that over ET in relation to unexpected Tembin's eastward deflection. This difference between two experiments is attributed to the fact that cold wake over WT increases the magnitude of SST gradient under the eastward SST gradient around East Asia and the resultant asymmetric flow deflects Typhoon Tembin eastward, which is mainly due to the different atmospheric response to the SST forcing between ET and WT. Therefore, it implies that the enhanced eastward SST gradient over East Asia results in larger typhoon deflection toward the region of warmer SST according to the location of the cold wake effect. This result can contribute to the improvement of track prediction for typhoons influencing the Korean Peninsula

• Journal of Korean Society for Atmospheric Environment
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• v.32 no.4
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• pp.372-383
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• 2016

This study aimed at analyzing the sensitivity of ozone simulation in accordance with the meteorological nudging for a high nocturnal ozone episode. To demonstrate the effectiveness of nudging methods (e.g., nudging techniques and application domains), the following six experiments were designed: (1) control without nudging, (2) experiment with application of observation nudging to all domains (domain 1~4), and (3)~(6) experiments with application of grid nudging to domain 1, domain 1~2, domain 1~3 and all domains, respectively. As a result, the meteorological nudging had a direct (improvement of input data) and indirect (estimate natural emission) effect on ozone simulation. Nudging effects during the daytime were greater than those during the nighttime due to low accuracy of wind direction during the nighttime. On comparison of the nudging techniques, the experiments in which grid nudging was applied showed more improved results than the experiments in which observation nudging was applied. At this time point, the simulated concentrations were generally similar to the observed concentrations due to the increase in the nudging effect when grid nudging was applied up to the sub-domain. However, for high nocturnal ozone uptakes, the experiment in which grid nudging was applied do domain 1~3 showed better results than the other experiments. This is because, when grid nudging was applied to the high resolution domain (e.g., domain 4 with 1 km), the local characteristics were removed due to the smoothing effects of meteorological conditions.

• Atmosphere
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• v.29 no.2
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• pp.183-196
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• 2019

High-quality and high-resolution meteorological information is essential to reduce damages due to disastrous weather phenomena such as flash flood, strong wind, and heat/cold waves. There are many meteorological observation stations operated by Korea Meteorological Administration (KMA) in Seoul Metropolitan Area (SMA). Nonetheless, they are still not enough to represent small-scale weather phenomena like convective storm cells due to its poor resolution, especially over urban areas with high-rise buildings and complex land use. In this study, feasibilities to use additional pre-existing networks (e.g., operated by local government and private company) are tested by investigating the effects of network density on the gridded horizontal distribution of two meteorological variables (temperature and precipitation). Two heat wave event days and two precipitation events are chosen, respectively. And the automatic weather station (AWS) networks operated by KMA, local-government, and SKTechX in Incheon area are used. It is found that as network density increases, correlation coefficients between the interpolated values with a horizontal resolution of 350 m and observed data also become large. The range of correlation coefficients with respect to the network density shows large in nighttime rather than in daytime for temperature. While, the range does not depend on the time of day, but on the precipitation type and horizontal distribution of convection cells. This study suggests that temperature and precipitation sensors should be added at points with large horizontal inhomogeneity of land use or topography to represent the horizontal features with a resolution higher than 350 m.

• Journal of Advanced Navigation Technology
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• v.22 no.6
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• pp.551-556
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• 2018

In recent years, drones have been used to measure aircraft flights data and weather information. Related applications include the measure for low-altitude atmospheric data, the measure for atmospheric fine dust, and the measure for air pollution. However, the mounting position of the atmospheric measurement sensor should be mounted by considering the effects of propeller flow, the EMI effects, and the changes in the weight of the drone. Among these, the upper flow of the propeller affects the wind speed and direction, so the optimal position should be selected. This study deals with the proper height of the atmospheric data measurement sensor. Through the flow analysis, we study the flow characteristics of around a drone and suggest the proper sensor mounting height.

• Atmosphere
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• v.30 no.4
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• pp.421-437
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• 2020

The effects of the terminal fall velocity-diameter relationship for raindrops, which is prescribed based on the measurement, on the simulated surface precipitation over Korea during summer season were investigated in our study. Two rainfall cases, 1-month summer precipitation and mesoscale rainfall, have been simulated using the Weather Research and Forecasting (WRF) model. The selected cloud microphysics parameterizations are WRF Single-Moment 5-class (WSM5) and WRF Single-Moment 6-class (WSM6) in the WRF model. The measured terminal fall-diameter relationship for raindrops by Gunn and Kinzer (1949) was applied in both WSM5 and WSM6. The sensitivity experiments with WSM5 and WSM6, applying the measured fall-diameter relationship, presents the different responses in simulated precipitation amount for the 1-month summer precipitation case. Precipitation increases with WSM5, thus enhancing the precipitation statistical skills. However, precipitation decreases with WSM6 leading to the deterioration of precipitation statistical skills. For the mesoscale rainfall case, precipitation increases with both WSM5 and WSM6, which further enhances the positive bias in precipitation amount.

• Journal of Korean Society for Atmospheric Environment
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• v.19 no.6
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• pp.733-743
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• 2003

The flow field in multiple fluid sphere systems was studied analytically. The expanded zero vorticity cell model based on Kuwabara's theory (1959) was applied and the effects of gas slippage at the collecting surface were considered. Also, the solid sphere system was extended to fluid sphere including the effects of the induced internal circulation inside the liquid droplet spheres or gas bubble systems. As a result, the obtained analytic solution was converged to the existing solutions for flow field around solid and bubble sphere systems with proper boundary conditions. Based on the resolved flow field, the terminal velocity around the collecting fluid spheres was obtained. Subsequently, this study evaluated the most general solution for flow field around the multiple fluid sphere systems. The obtained flow field in multiple fluid sphere could be used as a fundamental consideration of wet scrubber design and devices for removing particles by fluid-fluid interactions.

• Journal of Korean Society for Atmospheric Environment
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• v.13 no.1
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• pp.41-49
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• 1997

Status of photochemical air pollution in the Greater Seoul Area (GSA) between 1990 and 1995 was assessed in terms of frequency distributions, number of days exceeding standards, average concentration and meteorological effects. In Seoul compared with other areas in Korea, daily maximum concentration was higher but average concentration was not so high due to lower daily minimum from April to October. The top 5th percentile was high especially in summer season. Average number of days exceeding 100 ppb at monitoring stations in GSA was highest in 1994, the hottest year, but it was only 4 days a year. Mean meteorological pattern of high ozone days could be summarized as low wind speeds, high temperatures, strong solar radiation, and low precipitation. Westerlies were more frequent on high ozone days and at Pangi station located in the eastside of GSA, both number of high ozone days and average concentration were high. Effect of precursor transport on the rise of ozone concentration was, however, not consistently important on the whole in GSA.

• Journal of Korean Society for Atmospheric Environment
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• v.16 no.2
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• pp.165-178
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• 2000

In this study the effects of block distance have been investigated on the particle deposition efficiency in the collecting cell of two-stage electrostatic precipitator by numerical analysis. Particle trajectories have been changed by the electrostatic and inertial force of particle with the inlet velocity electrostatic number and particle diameter. The total deposition efficiency has a minimum value by the interaction between the effect of particle inertial force and electrostatic force in the collecting cell. The increase of block distance makes the total deposition efficiency decrease under the range of the particle size which has the minimum deposition efficiency. However beyond the range of particle size which has minimum deposition efficiency total deposition efficiency has no trend with the variation of block distance.