• 대한본초학회지
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• 제23권3호
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• pp.67-72
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• 2008

Objectives : This study presents a high performance liquid chromatography methods for the quantitative and qualitative analysis of rosmarinic acid (RA) and caffeic acid (CA) in Perilla frutescens var. japonica and var. acuta. Methods : Chromatographic separation was performed using a mixture of methanol, water and formic acid (35 : 64.2 : 0.8) with a reversed-phase column (Gemini C18, 4.6 ${\times}$ 150 mm, 3 ${\mu}m$). The analyses were detected at UV (280 nm). Results : The samples were extracted with 50% EtOH under reflux for 1 h, and simultaneous determination for RA and CA in hyang-so-san and haeng-so-san was possible without interference peaks Conclusions : According the results, we developed a determination method for RA and CA in Perillae Folium. Owing to Perilla frutescens var. japonica and var. acuta did not show significant difference in contents of RA and CA, both Perilla frutescens could be available as herbal medicine.

• 농업과학연구
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• 제10권1호
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• pp.22-27
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• 1983

보문산의 관목시(灌木尸)을 대상(對象)으로 수종(樹種)의 종군(種群) 분류(分類)와 천이(遷移) 계열(系列)을 추정(推定)하기 위하여 $5{\times}5m$의 quadrat 22개소(個所) 선정(選定)하였다. 관목(灌木)의 분석(分析)에는 reciprocal averaging(RA) ordination 방법(方法)을 사용(使用)하였으며 다음과 같은 결과(結果)를 얻었다. 1. 보문산에 출현(出現)한 관목수종(灌木樹種)은 45종(種)이었으며 우세종(優勢種)은 Quercus aliena, Quercus serrata, Rhododendron mucronulatum 등(等)이다. 2. RA ordination으로 분석(分析)한 결과(結果) 보문산의 관목(灌木)은 Zanthoxylum schinifolium에서 Spiraea prunifolia for. simpliciflora-Rubus crataegifolius 를 거쳐 Quercus류(類)로 천이(遷移)되며, 또 하나는 Stephanandra incisa-Corylus heterophylla에서 Lespedeza maximowiczii를 거쳐 Quercus류(類)로 천이(遷移)된다.

• The Journal of Korean Physical Therapy
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• 제26권6호
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• pp.453-458
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• 2014

Purpose: The purpose of this study was to compare the activities of the abdominal and neck flexor muscles of children with and without cerebral palsy (CP) while lifting the head in a supine position. Methods: The subjects were eight children with CP and eight children without the disease. The activities of the external abdominal oblique (EO), internal abdominal oblique (IO), rectus abdominis (RA), sternocleidomastoid (SCM), and RA/SCM muscles were collected by surface electromyography (EMG) when the children lifted their heads. A Mann-Whitney U test was used to compare the activity of each muscle during the head-lifting exercise. Statistical significance was accepted at p<0.05. Results: The activities of the EO, IO, and RA, and RA/SCM muscles differed significantly between the children with and without CP, but there was no significant between-group difference in the activity of the SCM muscle. Conclusion: These findings suggest that the abdominal muscles are not employed as much in the activities of children with CP compared to those without the disease. Additionally, those with CP were more dependent on the neck flexor muscle during the head-lifting exercise in a supine position.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2021년도 춘계학술대회
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• pp.514-515
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• 2021

본 논문은 LoRa 통신 환경에서 UAV를 이용하여 표적을 찾는 방법을 제시한다. 제안 된 방법은 사각 지대없이 목표 신호를 찾을 수 있도록 UAV 비행 경로를 제안한다. 비행 경로는 신호 강도의 변화를 사용하여 비행 중 전송 된 신호의 강도를 사용하여 변경되었습니다. 제안 된 방법을 시뮬레이션으로 검증하여 3 회 비행의 효율성은 높지만 목표 추적에 시간이 오래 걸리는 것을 확인했다. 목표를 찾는데 걸리는 시간을 줄이고 시간이 중요한 요소 일 때 효율성을 높이려면 3 대의 UAV를 비행하는 것이 가장 좋다. LoRa 통신은 생산 비용을 낮추고 저비용으로 시스템 구축을 가능하다.

• IMMUNE NETWORK
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• 제1권3호
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• pp.244-249
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• 2001

The transforming growth $factor-{\beta}$ ($TGF-{\beta}$) is a multifunctional cytokine modulating the onset and course of autoimmune disease as shown in experimental models. In synovial inflammation, there is a potential role for $TGF-{\beta}$ in repairment, the inhibition of cartilage and bone destruction, and the down-regulation of immune response. The biologic effects of $TGF-{\beta}$ depend on the cell type, the isoform and the availability of active $TGF-{\beta}$. We investigated $TGF-{\beta}$ expression in patients with rheumatoid arthritis (RA) and compared to those of osteoarthritis (OA). And we determined a correlation between $TGF-{\beta}1$ and $TGF-{\beta}2$, and also the relationships between each $TGF-{\beta}$ isoform and the parameters for disease activity of RA. Methods: The study population consisted of 20 patients with RA and 20 patients with OA. The commercial ELISA kit was used to study $TGF-{\beta}1$ and $TGF-{\beta}2$ levels in peripheral blood (PB) and synovial fluids (SF). Results: 1) While PB $TGF-{\beta}1$ level was of no difference between RA and OA patient groups, SF $TGF-{\beta}1$ level was higher in RA group than OA group. Similarly, PB $TGF-{\beta}2$ levels of RA and OA groups was not different, but SF $TGF-{\beta}2$ levels was higher in RA group than OA group. 2) In patients with RA, the $TGF-{\beta}1$ levels were higher than $TGF-{\beta}2$ in both the PB and SF, while in patients with OA, there showed higher readings for $TGF-{\beta}1$ than $TGF-{\beta}2$ in SF but no difference between $TGF-{\beta}1$ and $TGF-{\beta}2$ levels in PB. 3) In patients with RA, there were no correlations between PB $TGF-{\beta}1$ and PB $TGF-{\beta}2$ levels, nor between SF $TGF-{\beta}1$ and SF $TGF-{\beta}2$ levels. At the same way, there was no correlation between PB $TGF-{\beta}1$ and SF $TGF-{\beta}1$ levels, nor between each levels of $TGF-{\beta}2$ in patients with RA. 4) There was also no correlation between each $TGF-{\beta}$ isoform and the parameters for disease activity such as ESR, CRP, tender joint count, swollen joint count, rheumatoid factor, and the duration of morning stiffness except between in PB $TGF-{\beta}1$ and disease duration of RA (r=0.637, p<0.01). Conclusion: Each $TGF-{\beta}$ isoforms were higher in synovial fluid of patients with RA than that of patients with OA. The data from the RA patients demonstrated different patterns of expressions of the isoforms depending on which compartment (PB or SF) was investigated. The quantification of different $TGF-{\beta}$ isoform is thought to be important when $TGF-{\beta}$ is measured under disease conditions of RA.

• Journal of Korean Neurosurgical Society
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• 제58권1호
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• pp.89-92
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• 2015

Rheumatoid arthritis (RA) is a chronic inflammatory disease involving multiple joints. The cervical spine is often affected, and cases involving atlantoaxial joint can lead to instability. Anterior atlantoaxial subluxation in RA patients can lead to posterior neck pain or occipital headache because of compression of the C2 ganglion or nerve. Here, we report the successful treatment of a RA patient with occipital radiating headache using pulsed radiofrequency therapy at the C2 dorsal root ganglion.

• Biomolecules & Therapeutics
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• 제8권4호
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• pp.285-292
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• 2000

The effects of the members of the same nuclear receptor superfamily (all-trans retinoic acid (RA), thyroid hormone(T3) or hydrocortisone) on proliferation and differentiation in the SK-N-SH neuroblastoma (NB) cell lines were studied. NB cells were treated with RA, T3, or hydrocortisone at concentration of 10$^{-6}$ M or 10$^{-8}$ M for 3 days or 7 days. RA induced concentration- and time-dependent morphologic differentiation(neurite outgrowth and microtubule-associated protein expression) and growth inhibition in NB cells. Treatment of 10$^{-7}$ M T3 for 7 days increased viability and differentiation of NB cells. Treatment of 10$^{-6}$ M hydrocortisone for 7 days increased viability of NB cells. Although these three effectors are members of the same receptor superfamily, the regulation of brain development may be carried out in a different manner.

• Journal of Chest Surgery
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• 제25권1호
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• pp.17-22
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• 1992

The alterations in serum and urine potassium were studied in twenty two patients who underwent open heart surgery using extracorporeal circulation from June 1990 to August 1990 at the Department of Thoracic and Cardiovascular Surgery, School of Medicine, Kei-myung University. There were fifteen cases congenital heart disease and seven acquired heart disease. The serum and urine potassium levels were measured pre-, intra- and postoperatively until seventh postoperative day using ionic selective electrode measuring method. After general anesthesia, the serum potassium level decreased significantly but slowly increased during.cardiopulmonary bypass and returned preoperative level after operation. The urine potassium level decreased slowly from general anesthesia to cardiopulmonary bypass weaning but returned preoperative level following operation. During cardiopulmonary bypass, serum and urine potassium levels in diuretic group were lower than that of non diuretic group. There was no remarkable difference in the serum potassium level between single RA cannulation group and bicaval cannulation group preoperatively, but the serum potassium level in single RA cannulation group was much higher than that of bicaval cannulation group. There was no significant difference in the urine potassium level between single RA can-nulation group and bicaval cannulation group postoperatively.

• 한국임상수의학회지
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• 제18권3호
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• pp.211-214
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• 2001

The embolic effect of Gelfoam was investigated for transarterial embolization of renal artery (TAE-RA) in four normal rabbits. The catheter was selectively introduced into the unilateral renal artery under fluoroscopy and the Gelfoam-iohexol mixture was infused through a catheter into the renal arteries of 4 rabbits. The immediate and delayed (8 weeks) embolic effects on the renal arteries was investigated with selective angiography. The Gelfoam-iohexol was visualized under fluorosxopy in four rabbits. Renal arteries were ablated immediately after TAE-RA in four rabbits, however, opacification of renal parenchyma was visualized by injected contrast agent in 3 rabbits at 8 weeks. The Gelfoam-iohexol can be used as a short-term embolic materials for TAE-RA, however it is not adequate for permanent embolization of renal artery.

• Journal of Chest Surgery
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• 제16권3호
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• pp.316-321
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• 1983

Left ventricular-right atrial [LV-RA] shunt is a relatively uncommon defect but is being encountered with increasing frequency. The diagnosis is often not suspected on the basis of clinical findings and so the specific anatomic diagnosis depends upon the use of selective left ventriculography. Recently we experienced LV-RA shunt associated with PDA, which was underwent successful surgical correction under the cardiopulmonary bypass. On the preoperative diagnosis coexistence of PDA was overlooked and identified at the time of operation. The type of LV-RA shunt was supravalvular, which was closed by direct suture with pledget.