• 제목/요약/키워드: Asymptomatic population

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Trypanosoma brucei Infection in Asymptomatic Greater Kudus (Tragelaphus strepsiceros) on a Game Ranch in Zambia

  • Munang'andu, Hetron Mweemba;Siamudaala, Victor;Munyeme, Musso;Nambota, Andrew;Mutoloki, Stephen;Matandiko, Wigganson
    • Parasites, Hosts and Diseases
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    • 제48권1호
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    • pp.67-69
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    • 2010
  • Trypomastogotes of Trypanosoma brucei were detected from 4 asymptomatic kudus (Tragelaphus strepsiceros) on a game ranch located approximately 45 km north east of Lusaka, Zambia. Blood smears examined from 14 wildlife species comprising of the impala (Aepyceros melampus), Kafue lechwe (kobus leche kafuensis), sable antelope (Hippotragus niger), tsessebe (Damaliscus lunatus), warthog (Phacochoerus aethiopicus), puku (Kobus vardoni), zebra (Equus burchelli), waterbuck (Kobus ellipsiprymnus), bushbuck (Tragelaphus scriptus), reedbuck (Redunca arundinum), wilderbeest (Connochaetes taurinus), hartebeest (Alcephelus lichtensteini), African buffalo (Syncerus caffer), and kudu (Tragelaphus strepsiceros) showed that only the kudu had T. brucei. Although game ranching has emerged to be a successful ex-situ conservation strategy aimed at saving the declining wildlife population in the National Parks, our findings suggest that it has the potential of aiding the re-distribution of animal diseases. Hence, there is a need for augmenting wildlife conservation with disease control strategies aimed at reducing the risk of disease transmission between wildlife and domestic animals.

이하두정방사선사진과 개별화 단층방사선사진을 이용한 하악과두의 형태에 관한 연구 (A STUDY OF THE MANDIBULAR CONDYLE SHAPE ON THE INDIVIDUALIZED CORRECTED TMJ TOMOGRAPH AND SUBMENTOVERTEX RADIOGRAPH)

  • 이상래
    • 치과방사선
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    • 제24권2호
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    • pp.227-236
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    • 1994
  • The purpose of this study was to observe mandibular condyle shape in an asymptomatic population. In order to carry out this study, 96 temporomandibular joints in 48 adults(22 males, 26 females), who were asymptomatic for temporomandibular disturbances and had no history of prosthodontic or orthodontic treatments, were selected, and radiographed using the Sectograph(Denar Co., U.S.A.) for lateral and frontal individualized corrected TMJ tomograph and submentovertex radiograph. Mandibular condyles were classified morphologically, and measured medioateral and anteroposterior dimensions and condylar angulation. The obtained results were as follows. 1. In the classification of condyle shape on lateral tomographs, 94.8% were convex type and 5.2% were angled type. 2. In the classification of condyle shape on frontal tomographs, 45.3% were convex type, 32.0% were round type, 16.0% were flat type, and 6.7% were angled type. 3. In the classification of condyle shape on submentovertex radiographs, 34.5% were flat-convex type, 22.9% were flat-flat type, 20.8% were concave-convex type, 19.8% were convex-convex type, and 1.0% were concave-flat type and convex-flat type. Concave-concave type, convex-concave type, and flat-concave type were not observed. 4. The average mediolateral legth of the condyle was 19.3㎜ and the average anteroposterior length was 9.4㎜. The average angle between the long axis of condyle and the coronal plane made on submentovertex view was 19.6 degrees.

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절제 불가능한 4기 대장암에서 고식적 수술의 임상적 효과 (Clinical Impact of Palliative Surgery in Unresectable Stage IV Colorectal Cancer)

  • 이윤석
    • Journal of Digestive Cancer Research
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    • 제5권1호
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    • pp.32-36
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    • 2017
  • In unresectable stage IV colorectal cancer, the role of palliative surgery is not defined clearly. The palliative surgery can be categorized into two surgeries; first, palliative primary tumor resection; second, palliative metastatectomy. Several retrospective studies reported initial palliative systemic chemotherapy in unresectable stage IV colorectal cancer did not increase primary tumor related complications such as obstruction, perforation and hemorrhage, so they insisted that primary tumor resection in asymptomatic stage IV colorectal cancer should be preserved. However, in terms of overall survival and cancer-specific or progression-free survival, several retrospective studies, especially using population-based big data, reported favored survivals in palliative primary tumor resection group. And also several studies reported that palliative metastatectomy such as liver resection without resection of lung metastasis showed better overall survivals. But those results from those studies came from retrospective studies and are likely to be affected by selection bias. Prospective randomized studies are needed to define the benefit of palliative primary tumor resection and metastatectomy in unresectable stage IV colorectal cancer. However, based on the updated evidences, the dogma that palliative primary tumor resection should be preserved in asymptomatic unresectable stage IV colorectal cancer should be questioned.

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군 입영자에서의 B형 간염 발생 규모와 B형 간염 바이러스 보유자가 이에 미치는 영향 (The Incidence of Hepatitis B in Military Service and the Effect of Asymptomatic HBsAg Carriers on the Incidence)

  • 김록권;서일;남정모;한광협
    • Journal of Preventive Medicine and Public Health
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    • 제30권2호
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    • pp.267-278
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    • 1997
  • The purpose of this study was to investigate the incidence rate of hepatitis B in the military service and to examine the effect of the asymptomatic hepatitis B surface antigen(HBsAG) carries on the incidence of hepatitis B. The subject were 223,270 men who were conscripted to the Korean Army from 1991 to 1994. According to the conscripted year, four conscription cohort were constructed. At the screening examination for military service no test for hepatitis B were performed in 1991 and 1992. In 1993, a screening test for hepatitis B were performed and those who were confirmed as HBsAg positive o. showed high titers $(\geqq100IU)$ of nm glutamic-pyruvic transaminase(SGPT) were excluded from conscription. In 1994, the criteria for conscription was changed and those who were HBsAg positive were not excluded from conscription. Only those who showed $\geq$ SGPT 100IU were excluded. The main results were as follows ; 1. The positive rate of HBsAg is 5.5% in the conscripted men. 2. The incidence rates of the hepatitis B in 1991 and 1992 conscription cohort were 9.96 and 8.10 per ten thousand person-year, respectively. The incidence rate of the hepatitis B was 1.34 per ten thousand person-year in 1993 conscription cohort which was confirmed as HBsAg negative at the screning test, and 7.41 per ten thousand person-year in 1994 conscription cohort which included the HBsAg positive. 3. The incidence rate of hepatitis B was 99.98 per ten thousand person-year in HBsAg positive group and 2.25 per ten thousand person-year in HBsAg negative group. The incidence rate of the group with high SGPT and HBsAg positive was 255 times higher than that of normal population. 4. The incidence of hepatitis B in HBsAg negative group did not increase even though the probability of personal contact with HBsAg positive had been increased. from the above results, the men who have high SGPT with HBsAg positive should be excluded from military service, and it can not be said that asymptomatic HBsAg carriers influence on the hepatitis B incidence among the HBsAg negative through personal contact.

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한국인의 골반과 비구 골절에서 정맥 혈전색전증의 발병률 (Incidence of Venous Thromboembolism in Pelvic and Acetabular Fractures in the Korean Population)

  • 이상기;이재원;황정주
    • Journal of Trauma and Injury
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    • 제26권3호
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    • pp.74-80
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    • 2013
  • Purpose: There are no detailed reports on the incidence of venous thromboembolism (VTE) in pelvic and acetabular fractures in the Asian population. The purpose of this study was to investigate the incidence of VTE in pelvic and acetabular fractures in the Korean population. Methods: The cases of 67 Korean patients with pelvic and acetabular fractures treated at our hospital from January 2009 to February 2012 were analyzed retrospectively. Until May 2010, VTE screening was performed by contrast-enhanced computed tomography (CT) or ultrasonography (US) when the D-dimer value did not decline predictably, still exceeded $20{\mu}g/ml$ at 5 days after trauma and surgery, or increased to greater than $20{\mu}g/ml$ after a period of decline. After May 2010, contrast-enhanced CT and US were performed routinely irrespective of the D-dimer value. Physical prophylaxis was performed on all patients. The effects of the presence of a pelvic and/or acetabular fracture, and the effects of fracture type, accompanying injuries, and screening strategies on the incidences of VTE were investigated. Results: Overall, 26 patients(38.8%) were diagnosed with VTE and PTE in 14(20.9%). All were asymptomatic. Significantly higher incidences of VTE and PTE were observed in trauma patients with pelvic and acetabular fractures than in trauma patients without pelvic and acetabula fractures treated during the same period. No significant differences were observed in the incidences of VTE and PTE between patients with pelvic fractures, and patients with acetabular fractures or between patients with and without accompanying injuries. Compared with the previous screening strategy, the detection rates for VTE and PTE were higher for the newer screening strategy; however, the difference did not reach statistical significance. Conclusion: In the Korean population, we should be vigilant for a high incidence of VTE, especially PTE, in patients with pelvic and acetabular fractures.

Constant score in asymptomatic shoulders varies with different demographic populations: derivation of adjusted score equation

  • Nitesh Gahlot;Ankit Rai;Jeshwanth Netaji
    • Clinics in Shoulder and Elbow
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    • 제25권4호
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    • pp.274-281
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    • 2022
  • Background: In the present study, the age- and sex-adjusted Constant score (CS) in a normal Indian population was calculated and any differences with other population cohorts assessed. Methods: The study participants were patients who visited the outpatient department for problems other than shoulder and healthy volunteers from the local population. Patients without shoulder pain/discomfort during activity were included in the study. Subjects with any problem that might affect shoulder function (e.g., cervical, thoracic spine, rib cage deformity, inflammatory arthritis) were excluded. Constant scoring of all participants was performed by trained senior residents under the supervision of the senior faculty. Shoulder range of movement and strength were measured following recommendations given by the research and Development Committee of the European Society for Shoulder and Elbow Surgery (2008). A fixed spring balance was used for strength measurement; one end was fixed on the floor and the other end tied with a strap to the wrist of the participant, arm in 90° abduction in scapular plane with palm facing down. Results: Among the 248 subjects (496 shoulders), the average age was 37 years (range, 18-78 years), 65.7% were males (326 shoulders) and 34.3% females (170 shoulders). The mean CS was 84.6±2.9 (males, 86.1±3.0; females, 81.8±2.9). CS decreased significantly after 50 years of age in males and 40 years of age in females (p<0.05). The mean CS was lower than in previous studies for both males and females. Heavy occupation workers had higher mean CS (p<0.05). A linear standardized equation was estimated for calculating the adjusted CS for any age. Conclusions: Mean CS and its change with age differed from previous studies among various population cohorts.

Cytomegalovirus Infection and Memory T Cell Inflation

  • Kim, Jihye;Kim, A-Reum;Shin, Eui-Cheol
    • IMMUNE NETWORK
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    • 제15권4호
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    • pp.186-190
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    • 2015
  • Cytomegalovirus (CMV) infection in healthy individuals is usually asymptomatic and results in latent infection. CMV reactivation occasionally occurs in healthy individuals according to their immune status over time. T cell responses to CMV are restricted to a limited number of immunodominant epitopes, as compared to responses to other chronic or persistent viruses. This response results in progressive, prolonged expansion of CMV-specific $CD8^+$ T cells, termed 'memory inflation'. The expanded CMV-specific $CD8^+$ T cell population is extraordinarily large and is more prominent in the elderly. CMV-specific $CD8^+$ T cells possess rather similar phenotypic and functional features to those of replicative senescent T cells. In this review, we discuss the general features of CMV-specific inflationary memory T cells and the factors involved in memory inflation.

성인에서 우연히 발견되는 부비동혼탁화의 유병률 (Prevalence of incidental paranasal sinus opacification in an adult dental population)

  • 조봉혜;정연화
    • Imaging Science in Dentistry
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    • 제39권4호
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    • pp.191-194
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    • 2009
  • Purpose : The purpose of this study was to determine the prevalence of sinus opacification among adult dental patients. Materials and Methods : Five hundred and sixty-four Cone Beam Computed Tomography (CBCT) scans of dental patients over the age of 18 were reviewed for sinus opacification. Opacification was graded as clear, mild, moderate or severe. Patients with any sinus-related signs or symptoms were excluded. Results : Sinus opacification in one or more sinuses was found in 59.2% of the patients. The sinus opacification was mild in 49.8%, moderate in 8.3%, and severe in 1.1%. The maxillary (37.7%) and ethmoid (37.4%) sinuses were most frequently affected. The prevalence was higher in the older age group and showed a male predomination (p<0.05). Conclusion : Sinus opacification in asymptomatic adults is very common and emphasizes the importance of clinical correlation before deciding on the final diagnosis and treatment.

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Ectopic Preauricular Sinus in a Facial Cleft and Microtia Patient

  • Park, Jae Yeon;Lee, Seil;Kim, Hyo Joong;Jung, Sung Gyun
    • 대한두개안면성형외과학회지
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    • 제18권4호
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    • pp.287-291
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    • 2017
  • Preauricular sinus is a congenital malformation that is very commonly encountered among the general population and it has especially high prevalence among Asians when compared to other ethnic groups. It can often go unnoticed or easily overlooked by the patient or even by doctors because most of them are asymptomatic and is most of the time only a tiny pit that can be trivial in terms of aesthetics. We report a very rare and unique case that has no precedence what so ever; hence no reported case in the literature: an ectopic preauricular sinus in a facial cleft and microsomia patient.

경두개방사선사진과 측방 개별화 단층방사선사진을 이용한 하악과두의 형태와 위치에 관한 연구 (A RADIOGRAPHIC STUDY OF MANDIBULAR CONDYLE SHAPE AND POSITION: A COMPARISON OF TRANSCRANIAL RADIOGRAMS AND INDIVIDUALIZED CORRECTED TOMOGRAMS)

  • 이상래;황의환
    • 치과방사선
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    • 제27권1호
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    • pp.25-41
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    • 1997
  • The purpose of this study was to observe mandibular condyle shape and position in an asymptomatic population. In order to carry out this study, 142 temporomandibular joints in 71 adults(35 males, 36 females), who were asymptomatic for temporomandibular joint disorders and had no history of prosthodontic or orthodontic treatments, were selected, and radiographed using the Accurd-200 head holder(Denar Co., U.S.A) for transcranial radiograms and the Sectography(Denar Co., U.S.A) for lateral individualized corrected tomograms. Mandibular condyles were classified morphologically and evaluated in positional relationships with articular fossae and articular eminences at centric occlusion and 1 inch mouth opening. The obtained results were as follows; 1. In the classification of mandibular condyle shape, the convex type was more prevalent in transcranial radiograms and tomograms taken at medial, central, and lateral locations. 2. In the mandibular condyle position at centric occlusion, the mandibular condyles were placed posterior to the center of articular fossae in transcranial radiograms and anterior to the center of articular fossae in tomograms taken at medial, central, and lateral locations. 3. In the mandibular condyle position in right and left TMJs at centric occlusion, the mandibular condyles were placed bilateral asymmetric relationships to the articular fossae in transcranial radiograms and tomograms taken at medial, central, and lateral locations. 4. In the mandibular condyle position at 1 inch mouth opening, the mandibular condyles were placed anterior to the articular eminences in transcranial radiograms and tomograms taken at central location and posterior to the articular eminences in tomograms taken at medial and lateral locations.

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