• Title/Summary/Keyword: Asymptomatic disease

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Plasmaphresis therapy for pulmonary hemorrhage in a pediatric patient with IgA nephropathy

  • Yim, Dae-Kyoon;Lee, Sang-Taek;Cho, Heeyeon
    • Clinical and Experimental Pediatrics
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    • v.58 no.10
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    • pp.402-405
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    • 2015
  • IgA nephropathy usually presents as asymptomatic microscopic hematuria or proteinuria or episodic gross hematuria after upper respiratory infection. It is an uncommon cause of end-stage renal failure in childhood. Pulmonary hemorrhage associated with IgA nephropathy is an unusual life-threatening manifestation in pediatric patients and is usually treated with aggressive immunosuppression. Pulmonary hemorrhage and renal failure usually occur concurrently, and the pulmonary manifestation is believed to be caused by the same immune process. We present the case of a 14-year-old patient with IgA nephropathy who had already progressed to end-stage renal failure in spite of immunosuppression and presented with pulmonary hemorrhage during oral prednisone treatment. His lung disease was comparable to diffuse alveolar hemorrhage and was successfully treated with plasmapheresis followed by oral prednisone. This case suggests that pulmonary hemorrhage may develop independently of renal manifestation, and that plasmapheresis should be considered as adjunctive therapy to immunosuppressive medication for treating IgA nephropathy with pulmonary hemorrhage.

Duodenal Perforation Caused by an Inferior Vena Cava Filter

  • Bae, Mi-Ju;Chung, Sung-Woon;Lee, Chung-Won;Kim, Sang-Pil;Song, Seung-Hwan
    • Journal of Chest Surgery
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    • v.45 no.1
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    • pp.69-71
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    • 2012
  • The inferior vena cava (IVC) filter is known as an effective and safe method for preventing fatal pulmonary thromboembolism in patients with deep vein thrombosis. Usually, the remaining IVC filters are asymptomatic and do not cause clinical problems. We report a case of duodenal perforation caused by a remaining IVC filter.

Pneumonitis and pneumonia after aspiration

  • Son, Young Gon;Shin, Jungho;Ryu, Ho Geol
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.17 no.1
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    • pp.1-12
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    • 2017
  • Aspiration pneumonitis and aspiration pneumonia are clinical syndromes caused by aspiration. These conditions are clinically significant due to their high morbidity and mortality. However, aspiration as a preceding event are often unwitnessed, particularly in cases of asymptomatic or silent aspiration. Furthermore, despite the difference in treatment approaches for managing aspiration pneumonitis and aspiration pneumonia, these two disease entities are often difficult to discriminate from one another, resulting in inappropriate treatment. The use of unclear terminologies hinders the comparability among different studies, making it difficult to produce evidence-based conclusions and practical guidelines. We reviewed the most recent studies to define aspiration, aspiration pneumonitis, and aspiration pneumonia, and to further assess these conditions in terms of incidence and epidemiology, pathophysiology, risk factors, diagnosis, management and treatment, and prevention.

THE FLORID OSSEOUS DYSPLASIA OF THE JAWS (악골에 발생한 Florid Osseous Dysplasia의 방사선학적 연구)

  • Park Tae Won
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.19 no.1
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    • pp.19-22
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    • 1989
  • Three cases of florid osseous dysplasia of the jaw were investigated. Radiographs showed sclerotic. globular and ground glass opacities throughout the jaws. Two cases were asymptomatic but one case failed to heal following extraction of the mandibular molar and infection complicated the disease. These cases appear to represent the most exuberant manifestations of this reactive benign fibro-osseous lesion of the jaws.

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Three Cases of Internal Jugular Phlebectasia (내경 정맥 확장증 3례)

  • Choi, Ic Sun;Son, Kyung Ran;Kim, Byung Ju;Ma, Jae Sook
    • Clinical and Experimental Pediatrics
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    • v.45 no.8
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    • pp.1043-1047
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    • 2002
  • Phlebectasia is an abnormal dilatation of an isolated vein and a rare venous anomaly and is usually asymptomatic. Clinically internal jugular phlebectasia is a self limited benign condition and usually no treatment is required after initial diagnosis. So suspection of this disease and appropriate diagnostic approaches are essential to avoid unnecessary surgical intervention. We present three cases of internal jugular phlebectasia of which diagnosis was made by neck sonography and CT.

Thyroid dysfunction and subfertility

  • Cho, Moon Kyoung
    • Clinical and Experimental Reproductive Medicine
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    • v.42 no.4
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    • pp.131-135
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    • 2015
  • The thyroid hormones act on nearly every cell in the body. Moreover, the thyroid gland continuously interacts with the ovaries, and the thyroid hormones are involved in almost all phases of reproduction. Thyroid dysfunctions are relatively common among women of reproductive age, and can affect fertility in various ways, resulting in anovulatory cycles, high prolactin levels, and sex hormone imbalances. Undiagnosed and untreated thyroid disease can be a cause of subfertility. Subclinical hypothyroidism (SCH), also known as mild thyroid failure, is diagnosed when peripheral thyroid hormone levels are within the normal reference laboratory range, but serum thyroid-stimulating hormone levels are mildly elevated. Thyroid autoimmunity (TAI) is characterized by the presence of anti-thyroid antibodies, which include anti-thyroperoxidase and anti-thyroglobulin antibodies. SCH and TAI may remain latent, asymptomatic, or even undiagnosed for an extended period. It has also been demonstrated that controlled ovarian hyperstimulation has a significant impact on thyroid function, particularly in women with TAI. In the current review, we describe the interactions between thyroid dysfunctions and subfertility, as well as the proper work-up and management of thyroid dysfunctions in subfertile women.

Reverse Total Shoulder Replacement for an Enchondroma with Concomitant Rotator Cuff Tear Arthropathy: A Case Report

  • Park, Bong-Ju;An, Ki-Yong;Choi, Yong-Suk
    • Clinics in Shoulder and Elbow
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    • v.20 no.2
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    • pp.100-104
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    • 2017
  • Enchondromas generally occur in the hand and uncommonly in the long bones. Because enchondromas are usually asymptomatic, most are discovered during diagnostic radiology for another disease. Here, we describe a case of enchondroma in the right humerus in a 79-year-old female patient with concomitant rotator cuff tear arthropathy. The patient was initially hospitalized for prolonged pain and pseudoparalysis of the right shoulder. The condition, which was histologically confirmed as an enchondroma in the proximal humerus, was treated with curettage and reverse total shoulder arthroplasty. In this case report, we present a rare case of an enchondroma with combined rotator cuff tear arthropathy.

Surgical Treatment of "Dumb-bell" Neurosarcoma and Intrathoracic Meningocele Associated with Von Recklinghausen`s Disease -A case report- (신경섬유종증을 동반한 신경성 육종과 흉강내 뇌척수막류의 치험 1례)

  • 최순호
    • Journal of Chest Surgery
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    • v.28 no.10
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    • pp.946-950
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    • 1995
  • Neurosarcoma is relatively rare, but is seen frequently in association with stigmata of neurofibromatosis ie., Cafe au lait pigmentation and cutaneous neurofibromatosis. Both advanced age and association with neurofibromatosis increase the likelihood of malignant degeneration to neurosarcoma. It also may be dumb bell-shaped with intraspinal extension. Thoracic meningocele is rare and represents a protrusion of the dural sac through an abnormally large or malformed intervertebral foramen. The patient is usually asymptomatic, with evidence of paravertebral mass on the chest rentgenogram. In one operation we removed a "Dumb-bell" neurosarcoma and intrathoracic meningocele in a 52 year old woman using a cervical laminectomy with a trap-door incision. She was discharged at 17 days after the operation with a sequelae of excision of nerve roots C8 and T1. Postoperative radiation therapy was performed during the follow-up period.up period.

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A Case Report of HBsAg Seroclearance in Chronic Hepatitis B Patient

  • Lee, Hyeok Jae;Lee, Min-Hyeok
    • Korean Journal of Clinical Laboratory Science
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    • v.44 no.3
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    • pp.142-146
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    • 2012
  • Hepatitis B surface antigen (HBsAg) seroclearance is a rare event in chronic hepatitis B virus (HBV) infection which acquires the disease early in life. A case study have examined with asymptomatic chronic hepatitis B carrier who exhibits HBsAg seroclearance in anti-HBe positive. We comprehensively studied the biochemical, virological and clinical aspects of a patient with HBsAg seroclearance. Liver biochemistry, serological markers, serum HBV DNA levels, and development of clinical complications were monitored. Mutation of hepatitis B virus is suspected serum HBsAg detected by the HBsAg assay systems of VITROS (OrthoClinical Diagnostics, USA), AxSYM (Abbott Laboratories, USA), Elecsys (Roche Diagnostics, Germany) and ADVIA Centaur (Bayer Diagnostics, USA). These four immunoassays showed negative results. Also, the patient had undetectable serum HBV DNA. Therefore, no mutation within the "a" determinant of HBsAg, which might escape detection from HBsAg immunoassay were found. Natural seroclearance was confirmed.

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Pancreatic Cancer: Pathogenesis and Diagnosis

  • Goral, Vedat
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5619-5624
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    • 2015
  • Pancreatic cancer is a fatal malignancies which is predominantly seen in men and at advanced age (40-85 years) and has an aggressive course. Its frequency is gradually increasing over the past years. It accounts for 2% of all cancers and 5% of cancer-related deaths. Pancreatic cancer takes the first place among asymptomatic cancers. Ninety percent of cases are adenocarcinomas. Ten percent of the patients have a familial disposition. The disease is very difficult to detect as it has no early signs and spreads rapidly to surrounding organs is one of the most deadly types of cancer. Pancreatic cancer may result from hereditary germline or somatic acquired mutations in cancer-related genes and mutations also cause cancer progression and metastasis.