• Title/Summary/Keyword: Association mapping

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Mapping the Terms of Medicinal Material and Formula Classification to International Standard Terminology

  • Kim, Jin-Hyun;Kim, Chul;Yea, Sang-Jun;Jang, Hyun-Chul;Kim, Sang-Kyun;Kim, Young-Eun;Kim, Chang-Seok;Song, Mi-Young
    • International Journal of Contents
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    • v.7 no.4
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    • pp.108-115
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    • 2011
  • The current study aims to analyze the acceptance of International Standard Terminology (IST) related to herbs and formulas used in Korea. It also intends to examine limitations of each term source by linking texts for herbal medicine research and formula research used in schools of oriental medicine with medicinal substance-formula classification names within the IST framework. This study examined 64 medicinal classification names of IST, including synonyms, 41 formula classification names, 65 classification names of "Herbal Medicine Study," 89 medicinal classification names of "Shin's Clinical Herbal Medicine Study," and lastly 83 formula classification names of "Formula Study." Data on their chief virtue, efficacy and characteristics as medicinal substances were extracted from their definitions, and such data were used to perform Chinese character-English mapping using the IST. The outcomes of the mapping were then analyzed in terms of both lexical matching and semantic matching. In terms of classification names for medicinal substances, "Herbal Medicine Study" had 60.0% lexical matching, whereas "Shin's Clinical Herbal Medicine Study" had 48.3% lexical matching. When semantic matching was also applied, "Herbal Medicine Study" showed a value of 87.7% and "Shin's Clinical Herbal Medicine Study" 74.2%. In terms of formula classification names, lexical matching was 28.9% of 83 subjects, and when semantic matching was also considered, the value was 30.1%. When the conceptual elements of this study were applied, some IST terms that are classified with other codes were found to be conceptually consistent, and some terms were not accepted due to different depths in the classification systems of each source.

Molecular Characterization and Chromosomal Mapping of the Porcine AMP-activated Protein Kinase ${\alpha}2$ (PRKAA2) Gene

  • Lee, Hae-Young;Choi, Bong-Hwan;Lee, Jung-Sim;Jang, Gul-Won;Lee, Kyung-Tai;Chung, Ho-Young;Jeon, Jin-Tea;Cho, Byung-Wook;Lee, Jun-Heon;Kim, Tae-Hun
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.5
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    • pp.615-621
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    • 2007
  • AMP-activated protein kinase alpha 2 (PRKAA2) plays a key role in regulation of fatty acid and cholesterol metabolism. This study investigated the porcine PRKAA2 gene as a positional candidate for intramuscular fat and backfat thickness traits in pig chromosome 6. A partial fragment of the porcine PRKAA2 gene, amplified by PCR, contained a putative intron 3 including a part of exon 3 and 4, comparable with that of human PRKAA2 gene. Within the fragment, several single nucleotide polymorphisms were identified using multiple sequence alignments. Of these, TaqI restriction enzyme polymorphism was used for genotyping various pig breeds including Korean reference family. Using linkage and physical mapping, the porcine PRKAA2 gene was mapped in the region between microsatellite markers SW1881 and SW1680 on chromosome 6. Allele frequencies were quite different among pig breeds. The full length cDNA of the porcine PRKAA2 (2,145 bp) obtained by RACE containing 1,656 bp open reading frame of deduced 552 amino acids, had sequence identities with PRKAA2 of human (98.2%), rat (97.8%), and mouse (97.5%). These results suggested that the porcine PRKAA2 is a positional candidate gene for fat deposition trait at near telomeric region of the long arm of SSC 6.

Effect of Child Care Center Director's Work Stress and Servant Leadership on Burnout: The Moderating Role of Organizational Stewardship (어린이집 원장의 스트레스 및 서번트 리더십이 소진에 미치는 영향: 청지기 정신의 조절효과를 중심으로)

  • Kim, Yu Mi;Chung, Hana
    • Human Ecology Research
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    • v.55 no.6
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    • pp.649-659
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    • 2017
  • This study investigated the effect of a child care center directors' work stress and awareness of their servant leadership on burnout. The subjects of this study were 200 child care center directors in Incheon. They responded to 'Work Stress Scale', 'Maslach Burnout Inventory (MBI)', 'Servant Leadership Scale'. There were five subscales of Servant Leadership Scale (altruistic calling, emotional healing, wisdom, persuasive mapping, and organizational stewardship). Data were analyzed by frequency, percentage, mean, standard deviation, Pearson's correlation and hierarchical regression. Moderating effects were examined using analysis procedures of Baron and Kenny. The major results were as follows. First, child care center directors' burnout and work stress were positively correlated. Child care center directors' burnout and awareness of their servant leadership (emotional healing, wisdom, persuasive mapping, and organizational stewardship) was negatively correlated. Second, child care center directors' work stress, emotional healing, persuasive mapping and organizational stewardship affected their burnout. This means that the work stress of child care center directors increases their burnout. However, the child care center director's servant leadership is a factor in reducing burnout. Third, child care center directors' work stress and organizational stewardship had an interaction effect on burnout. The results suggests that child care center directors' organizational stewardship needs to be considered as an important factor for decreasing their own burnout. We also discussed implications and suggestions for future research and policy makers.

A Bibliometric Approach for Department-Level Disciplinary Analysis and Science Mapping of Research Output Using Multiple Classification Schemes

  • Gautam, Pitambar
    • Journal of Contemporary Eastern Asia
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    • v.18 no.1
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    • pp.7-29
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    • 2019
  • This study describes an approach for comparative bibliometric analysis of scientific publications related to (i) individual or several departments comprising a university, and (ii) broader integrated subject areas using multiple disciplinary schemes. It uses a custom dataset of scientific publications (ca. 15,000 articles and reviews, published during 2009-2013, and recorded in the Web of Science Core Collections) with author affiliations to the research departments, dedicated to science, technology, engineering, mathematics, and medicine (STEMM), of a comprehensive university. The dataset was subjected, at first, to the department level and discipline level analyses using the newly available KAKEN-L3 classification (based on MEXT/JSPS Grants-in-Aid system), hierarchical clustering, correspondence analysis to decipher the major departmental and disciplinary clusters, and visualization of the department-discipline relationships using two-dimensional stacked bar diagrams. The next step involved the creation of subsets covering integrated subject areas and a comparative analysis of departmental contributions to a specific area (medical, health and life science) using several disciplinary schemes: Essential Science Indicators (ESI) 22 research fields, SCOPUS 27 subject areas, OECD Frascati 38 subordinate research fields, and KAKEN-L3 66 subject categories. To illustrate the effective use of the science mapping techniques, the same subset for medical, health and life science area was subjected to network analyses for co-occurrences of keywords, bibliographic coupling of the publication sources, and co-citation of sources in the reference lists. The science mapping approach demonstrates the ways to extract information on the prolific research themes, the most frequently used journals for publishing research findings, and the knowledge base underlying the research activities covered by the publications concerned.

Cross Mapping of Standardized Nursing Diagnoses and Problems with NANDA-I in 4 Tertiary Hospitals (표준화된 간호진단 및 문제와 NANDA-I 교차분석: 4개 상급종합병원 사례를 중심으로)

  • Song, Mi Ra;Shim, So Yun;Kim, Dae Sung;Lee, Kyung Soon;Lee, Yu Na;Won, Mi Suk
    • Journal of Korean Clinical Nursing Research
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    • v.26 no.3
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    • pp.374-384
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    • 2020
  • Purpose: To explore the scope and method of applying standardized nursing terminologies to nursing diagnosis and problems used in nursing practice. Methods: A descriptive study was done with a retrospective analysis of the nursing records of 141,420 patients that were hospitalized in 4 tertiary hospitals. The nursing diagnosis and problems collected from the records were standardized, and the standardized nursing diagnosis and problems cross mapped with NANDA-I, confirmed in a nursing focus group. Results: 65 (67.7%) of the 96 standardized nursing diagnosis and problems were equal with NANDA-I and included in the 10 domains of NANDA-I. Among 86 nursing diagnosis and problems excluded from the cross mapping with NANDA-I, the 63 terms (73.3%) related to surgery/procedure were the most common. Conclusion: It is meaningful that multi-tertiary hospital nursing diagnosis and problems were standardized and cross mapping with standard nursing terminologies was performed. As for the method of applying standardized nursing terminologies in nursing practice, it is appropriate to use several standardized nursing terminologies complementarily.

What is the masculinity of Korean men? Concept mapping of masculinity (한국 남성의 남자다움은 무엇인가?: 남성성에 대한 개념도 연구)

  • Woo Sungbum
    • Korean Journal of Culture and Social Issue
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    • v.25 no.3
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    • pp.203-229
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    • 2019
  • The purpose of this study was to identify the factors that constitute masculine norms of masculine in Korean society. The definition of masculinity was to conform to the male-dominated standard formed socially and culturally. The results of in-depth interviews with 20 male participants were used for a concept mapping analysis to explore the configural representations of Korean masculine norms. After extracting the key sentences related to masculine norms, the participants sorted the 55 key sentences based on similarities and assessed the importance, which was then analyzed with multidimensional scaling method and cluster analysis. The result showed two dimensions, one representing social-personal domain and the other implying dominance-support domain as well as six clusters of caregiver, leadership, emotion suppression, job ability and organizational social adaptation, Expects the masculine abilities, power and control. Finally, the implications of this study, limitations, and the suggestions for future research were discussed.

Mapping Poverty Distribution of Urban Area using VIIRS Nighttime Light Satellite Imageries in D.I Yogyakarta, Indonesia

  • KHAIRUNNISAH;Arie Wahyu WIJAYANTO;Setia, PRAMANA
    • Asian Journal of Business Environment
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    • v.13 no.2
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    • pp.9-20
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    • 2023
  • Purpose: This study aims to map the spatial distribution of poverty using nighttime light satellite images as a proxy indicator of economic activities and infrastructure distribution in D.I Yogyakarta, Indonesia. Research design, data, and methodology: This study uses official poverty statistics (National Socio-economic Survey (SUSENAS) and Poverty Database 2015) to compare satellite imagery's ability to identify poor urban areas in D.I Yogyakarta. National Socioeconomic Survey (SUSENAS), as poverty statistics at the macro level, uses expenditure to determine the poor in a region. Poverty Database 2015 (BDT 2015), as poverty statistics at the micro-level, uses asset ownership to determine the poor population in an area. Pearson correlation is used to identify the correlation among variables and construct a Support Vector Regression (SVR) model to estimate the poverty level at a granular level of 1 km x 1 km. Results: It is found that macro poverty level and moderate annual nighttime light intensity have a Pearson correlation of 74 percent. It is more significant than micro poverty, with the Pearson correlation being 49 percent in 2015. The SVR prediction model can achieve the root mean squared error (RMSE) of up to 8.48 percent on SUSENAS 2020 poverty data.Conclusion: Nighttime light satellite imagery data has potential benefits as alternative data to support regional poverty mapping, especially in urban areas. Using satellite imagery data is better at predicting regional poverty based on expenditure than asset ownership at the micro-level. Light intensity at night can better describe the use of electricity consumption for economic activities at night, which is captured in spending on electricity financing compared to asset ownership.

Mapping, Tissue Distribution and Polymorphism Study of the Porcine SOCS2 and SOCS3 Genes

  • Li, X.Y.;Liu, B.;Fan, B.;Yu, M.;Zhu, M.J.;Xiong, T.A.;Li, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.2
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    • pp.165-170
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    • 2006
  • Using the somatic cell hybrid panel (SCHP) and radiation hybrid (IMpRH) panel, porcine SOCS2 gene was mapped at SSC5 (1/2) q21-q24 and closely linked with SW1383 marker (47 cR in distance), while SOCS3 gene was assigned to SSC12p11-(2/3p13) and closely linked with SW2490 (43 cR). The reverse transcriptase-polymerase chain reaction (RT-PCR) was performed to detect the expression of these two genes in the different tissues and the results showed that both SOCS2 and SOCS3 genes were widely expressed in tissues investigated (heart, liver, spleen, lung, kidney skeletal muscle, fat and brain), although some tissues showed lower gene expression. Moreover, SOCS2 and SOCS3 genes had different expression levels at different stages, in different tissues and in different breeds. A G/A substitution, which can be recognized by restriction enzyme of Cfr421, was observed in 5' untranslated region (5'-UTR) of SOCS2 gene. The allele frequencies was investigated by PCR-restriction fragment length polymorphism (PCR-RFLP) method and it showed that the allele frequency among Dahuabai, Erhualian, Yushan, Qingping, Large white and Landrace tested were different. Association analysis in a cross experimental populations revealed no significant association between the SOCS2 gene polymorphism and the economic traits investigated. The full-length coding regions (CDs) of porcine SOCS3 gene was obtained by RT-PCR.

Dynamic Universal Variable Length Coding with Fixed Re-Association Table (고정 재배정 테이블 기반 동적 UVLC 부호화 방법)

  • Choe, Ung-Il;Jeon, Byeong-U;Yu, Guk-Yeol;Cheon, Gang-Uk
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.39 no.2
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    • pp.56-68
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    • 2002
  • The Universal Variable Length Coding(UVLC) scheme in H.26L has nice features such as error resiliency and two-way decodability. However, it has lower coding efficiency than the conventional Huffman coding. To improve the coding efficiency of UVLC, we Propose to use a dynamic codeword mapping that changes association between symbols and codewords in order to utilize the statistical characteristics of symbols as much as possible but without losing any features of the UVLC. Both encoder and decoder use the same re-association table, and hence the encoder need not send additional overhead for the re-mapping relationship to the decoder. Simulation results show that without significant change of the current H.26L coding scheme, the proposed method additionally attains up to about 8% and about 5% bit reductions respectively in intra and inter frames over the current H.26L encoding method.

New Sources of Resistance and Identification of DNA Marker Loci for Sheath Blight Disease Caused by Rhizoctonia solani Kuhn, in Rice

  • Pachai, Poonguzhali;Ashish, Chauhan;Abinash, Kar;Shivaji, Lavale;Spurthi N., Nayak;S.K., Prashanthi
    • The Plant Pathology Journal
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    • v.38 no.6
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    • pp.572-582
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    • 2022
  • Sheath blight disease caused by the necrotrophic, soilborne pathogen Rhizoctonia solani Kuhn, is the global threat to rice production. Lack of reliable stable resistance sources in rice germplasm pool for sheath blight has made resistance breeding a very difficult task. In the current study, 101 rice landraces were screened against R. solani under artificial epiphytotics and identified six moderately resistant landraces, Jigguvaratiga, Honasu, Jeer Sali, Jeeraga-2, BiliKagga, and Medini Sannabatta with relative lesion height (RLH) range of 21-30%. Landrace Jigguvaratiga with consistent and better level of resistance (21% RLH) than resistant check Tetep (RLH 28%) was used to develop mapping population. DNA markers associated with ShB resistance were identified in F2 mapping population developed from Jigguvaratiga × BPT5204 (susceptible variety) using bulk segregant analysis. Among 56 parental polymorphic markers, RM5556, RM6208, and RM7 were polymorphic between the bulks. Single marker analysis indicated the significant association of ShB with RM5556 and RM6208 with phenotypic variance (R2) of 28.29 and 20.06%, respectively. Co-segregation analysis confirmed the strong association of RM5556 and RM6208 located on chromosome 8 for ShB trait. This is the first report on association of RM6208 marker for ShB resistance. In silico analysis revealed that RM6208 loci resides the stearoyl ACP desaturases protein, which is involved in defense mechanism against plant pathogens. RM5556 loci resides a protein, with unknown function. The putative candidate genes or quantitative trait locus harbouring at the marker interval of RM5556 and RM6208 can be further used to develop ShB resistant varieties using molecular breeding approaches.