• Korean Journal of Occupational Health Nursing
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• v.30 no.4
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• pp.167-174
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• 2021

Purpose: This study aimed to identify how job stress and teaching efficacy impacted organizational commitment. Methods: Data were collected from 158 nursing professors via an online survey, from Jan to June 2019. Results: The study found that four factors affected the organizational commitment of nursing professors: i) type of nursing institution in which they are currently employed (β=-.16, p=.030), ii) position as an assistant professor (β=-.37, p=.012) and an associate professor (β=-.44, p=.002), iii) salary in the 50-59 million won range (β=.20, p=.024), and above 60 million won (β=.41, p<.001), and iv) professor's teaching efficacy (β=-.18, p<.016). Conclusion: To increase the organizational commitment of four-year university professors, job characteristics should be considered. In the case of lower positions and salaries, additional compensation and programs that increase school affiliation should be introduced. Teaching methods training, lecture evaluation monitoring programs, and clinical training may also improve teaching efficacy.

• Lingua Humanitatis
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• v.2 no.2
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• pp.349-362
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• 2002

The paper argues for the necessicity of revising many fundamental concepts that we use in everyday situations and in communication such as reality, thought, language, the world and finally the truth. The paper develops the argument that what the word ′truth′ actually signifies cannot be addressed just by explicating what philosophy, science or even religion denote but that it can only be answered fully by the study of language and therefore in a larger context linguistics. Language is the very tool that enriches the communication between one another due to its diverse significations that one may use when expressing one′s views, thereby making life more enjoyable. The paper develops why the above corresponding argument should be justified by developing three outstanding views as follows. The world or reality is indistinguishable from the common worldview that we associate with without the means of language. That the worldview is in essence inseparable from the mental and intellectual representation of it and the only means of expression lies with language. And finally, that the language is a complex signification in itself in every aspect. Language in short is the very essence of what we define as being ′poetic.′ With these arguments in mind, we may once again ponder the signification of Nietzsche′s words when he states that "to see science through the lens of art, and art through the lens of life."

• Journal of Life Science
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• v.9 no.1
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• pp.76-83
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• 1999

Mammalial expression vectors containing GRP94, BiP, ERp72, and PDI, were introduced into FRTL5 cells. Transfected cells were selected by neomycin resistance for exogenously overexpressed proteins in the ER. The use of a reducible cross-linker, DSP, markedly improved the ability to detect noncovalent interactions of PDI, BiP and GRP94 with newly-synthesized thyroglobulin. Under normal conditions, GRP94 was found to associate transiently with early Tg folding intermediates, displaying interaction kinetics similar to those reported for another ER chaperones of BiP.

• Journal of Environmental Science International
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• v.23 no.4
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• pp.649-660
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• 2014

Spatial and temporal patterns of precipitation and temperature occur with regard to aspect and elevation of Mt. Halla in Jeju Island. Therefore, there is a need to predict regional drought associate with them to mitigate of impacts of drought. In this study, regional drought is predicted based on Palmer drought severity index (PDSI) and standardized precipitation index (SPI) using future (2015~2044) climate change scenario RCP (representative concentration pathways) 4.5 classified as 24 regions according to aspect and elevation. The results show that number and duration of drought will be decrease in Jeju Island. However, severity of severe drought will be increase in western and northern aspect with under 200 meters above mean sea level. These findings provide primary information for developing the proactive strategies to mitigate impacts of drought by future climate change in Jeju Island.

• Biomedical Science Letters
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• v.19 no.2
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• pp.164-167
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• 2013

Osteoclasts are originated from hemopoietic progenitors of the monocyte/macrophage lineage and resorb mineralized tissues. Elevated osteoclast numbers and activity result in bone disease such as osteoporosis, Paget's disease, and tumor osteolysis. In order to identify the genes that are involved in osteoclast differentiation, microarray was performed after treated with RANKL for 12 h and 24 h in osteoclast precursors. The genes that changed by RANKL treatment were grouped by biological process or molecular function. Among them, the number of genes involved in signal transduction and nucleic acid binding was 6065 and 3066, respectively. When analyzed the number of genes changed more than 1.5 fold in the cells treated with RANKL for 12 h or 24 h compared to when RANKL was not treated, 83 and 62 genes were up-regulated; 56 and 62 genes were downregulated, respectively. To verify the microarray results, real-time RT-PCR for Cxcl1 and Slfn1genes that have not been reported yet related to osteoclast differentiation, as well as Ccl2 gene associated with osteoclast differentiation were carried out. Both experiments showed a similar result of more than 1.5 fold induction of these genes by RANKL treatment. These results suggest the possibility that Cxcl1 and Slfn1 may associate with osteoclastogenesis and provide that microarray is a useful tool to analyze the profile of genes changed during osteoclast differentiation by RANKL. Moreover, this gene profile contributes to understand the regulatory mechanisms involved in osteoclast differentiation and the pathogenesis, thus developing therapeutics of bone diseases such as osteoporosis.

• Journal of the Korean Operations Research and Management Science Society
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• v.25 no.2
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• pp.23-31
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• 2000

Many studies in marketing and economics have attempted to model price and sales path under the dynamic diffusion process. Most of these models have been based on a fixed product lifetime. The current business climate requiring intensive development of new products however affects the diffusion of new products and their lifetime. Many products have not enjoyed the expected life cycle at the launching stage due to intense technical development competitive reactions, and financial problems. Most diffusion models however have not taken account of the lifetime uncertainty of new product. If the products do not last over the planning horizon set by those models. the optimal price derived from them could be futile. Therefore we had better take such lifetime uncertainty into consideration when developing diffusion models, In this paper we study the impact of uncertain product lifetime on its optimal pricing path in non-competitive market. We develop an optimal pricing model under uncertain product lifetimes and conduct a simulation study to investigate their effects on the optimal pricing and corresponding sales paths. The simulation study provides some interesting findings on optimal pricing policy under uncertain product lifetime. This study could be a stepping stone for the further extended study of optimal pricing strategy with uncertain product lifetime.

• Annual Conference of KIPS
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• 2008.05a
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• pp.459-462
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• 2008

레이블링은 웹 사이트의 요소가 되는 글로벌 네비게이션, 서브 메뉴, 컨텐츠 등에 명칭을 붙이고 체계를 확립해 주어 사용자들에게 이해를 돕기 위한 가이드라인이다. 특히, 취업 정보 시스템에서 이력서나 채용공고 등과 같은 정보 입력 항목의 레이블로 사용하는 용어는 정확한 예측과 빠른 이해가 있어야 입력시간을 단축 할 수 있다. 본 연구에서는 웹사이트를 사용하는 다양한 요구와 사고들을 충족하면서 많은 입력 정보 항목의 이해도를 높여 이력서나 채용공고 등과 같은 정보를 입력 시 정확한 예측과 빠른 이해를 도와 입력시간을 단축시킬 수 있는 레이블명에 대해 알아보고자 한다. 연구 방법으로는 국내 취업사이트 중 상위 랭킹에 있는 사이트를 중심으로 정보 입력 항목의 이명 레이블을 벤치마킹하고 다양한 레이블 중 사용자가 친숙하면서도 직관적으로 생각하는 레이블을 설문 조사한다. 설문 조사 결과를 바탕으로 취업사이트에서 벤치마킹한 최빈도 사용 레이블명이 높은 친숙도 평가값을 받은 항목의 레이블과 비교하여, 향후 취업 정보 시스템을 구성 할 경우 정보 항목의 레이블을 효과적으로 결정할 수 있는 방법을 제안하고 그 유효성을 확인하고자 한다.

• Journal of Animal Science and Technology
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• v.53 no.6
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• pp.511-516
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• 2011

Fas gene known to associate with intramuscular fat content in Korean cattle was selected for DNA marker development. Fas (APO-1, CD95), a member of the tumor necrosis factor (TNF) receptor superfamily, is a cell membrane protein that mediates apoptosis (programmed cell death). We discovered single nucleotide polymorphisms (SNPs) within Fas gene in order to develop novel DNA markers at genomic level. Of this gene to search for SNP, sequences of whole exon and 1kb range of both front and back of the gene using 24 cattle were determined by direct-sequencing methods. As a result, 16 SNPs in exon, 37 SNPs in intron and 2 SNPs in promoter region, a total of 55 SNPs were discovered. In these SNPs, thirty-one common polymorphic sites were selected considering their allele frequencies, haplotype-tagging status and Linkage Disequilibrium (LD) for genotyping in larger-scale subjects. Selected SNPs were confirmed genotype through SNaPshot method (n=274) and were examined for possible genetic association of Fas polymorphisms with carcass weight (CWT), eye muscle area (EMA), and backfat thickness (BF). So, the SNP have been identified significant g.-12T>G, g.1112T>G and g.32548T>C. These results suggest that polymorphism of Fas gene was associated with meat quality traits in Hanwoo.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.9
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• pp.1342-1348
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• 2007

POU1F1 is a positive regulator for GH, PRL and TSH${\beta}$ and its mutations associate with production traits in ruminant animals. We described a DdeI PCR-RFLP method for detecting a silent allele in the goat POU1F1 gene: TCT (241Ser)>TCG (241Ser). Frequencies of $D_1$ allele varied from 0.600 to 1.000 in Chinese 801 goats. Significant associations of DdeI polymorphism with production traits were found in milk yield (*p<0.05), litter size (*p<0.05) and one-year-old weight (*p<0.05) between different genotypes. Individuals with genotype $D_1D_1$ had a superior performances when compared to those with genotype $D_1D_2$ (*p<0.05). Hence, the POU1F1 gene was suggested to the potential candidate gene for superior milk performance, reproduction trait and weight trait. Genotype $D_1D_1$, characterized by a DdeI PCR-RFLP detection, was recommended to geneticists and breeders as a molecular marker for better performance in the goat industry.

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.59-59
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• 2022

The transplanting date of rice affects grain yield and quality, and it is changed by the environment during cultivation. Thus, it is important to provide the optimal transplanting dates for rice growers under global warming environment. In this study, transplanting date experiments with thirty-day-old seedlings of three cultivars (early, mid, and mid-late maturity) were conducted at the National Institute of Crop Science in Suwon from 2018 to 2021 to determine the optimal transplanting dates for and quantify the effect of planting dates on yield and quality. Transplanting date was strongly associated with culitvar across every year. Clear relationships between transplanting date and head rice yield in early and mid-late maturing rice varieties were observed, and the highest head rice yields were observed during transplantings in mid and late June for early maturing cultivar and mid June for mid-late maturing cultivar. It is obvious that the optimal rice transplanting dates have been shifted and are better later than the optimal transplanting dates in 2002-2004. Days to heading was also strongly associated with the transplanting date and cultivar with 89% of the variation explained. Days to heading was reduced in the later transplanting dates. Grain yield was strongly associate with biomass production during ripening(R²=0.85), however translocated biomass from leaf and stem showed little association with grain yield. The results from this study reconfirmed the importance of shifting optimal transplanting dates to maximize head rice yield for the Mid-plain area in South Korea.