• Journal of the Korea Safety Management & Science
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• v.23 no.3
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• pp.11-18
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• 2021

As the number of confirmed cases of Covid-19 is not decreasing, it is time for domestic companies to respond preemptively and in terms of business continuity. The purpose of this study is to present measures to strengthen BCP to prevent infectious diseases in the enterprise. In this work, three methods of data investigation are used. The first was to search for keywords in academic databases such as the National Assembly Library and the Korea Research and Information Service to investigate degree papers and academic papers. Second, we investigated literature such as research reports, manuals, and guidelines on infectious diseases. Finally, the researchers visited official websites such as KDCA, MOHW, and MOIS to collect and analyze recent data. BCP In view of the Board, a new risk analysis should be made and a disaster preparedness system tailored to the characteristics of the entity should be established. We need to analyze corporate weaknesses and focus on safety culture. It is also important to look at how customers choose their services and products. Based on this, differentiated service strategies should be presented. It is hoped that the results of this study can be used as basic data for companies that want to systematically manage and operate BCP to prevent infectious diseases.

• Steel and Composite Structures
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• v.29 no.5
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• pp.603-622
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• 2018

Precast concrete structures are erected from individual prefabricated components, which are assembled on-site using different types of connections. In the present design of these structures, beam-to-column connections are assumed pin jointed. Bolted billet beam to-column connections have been used in the precast concrete industry for many years. They have many advantages over other jointing methods in component production, quality control, transportation and assembly. However, there is currently limited information concerning their detailed structural behaviour under vertical loadings. The experimental work has involved the determination of moment-relative rotation relationships for semi-rigid precast concrete connections in full-scale connection tests. The study reported in this paper was undertaken to clarify the behaviour of such connections under symmetrical vertical loadings. A series of full-scale tests was performed on sample column for which the column geometry and bolt arrangements conformed to successful commercial practice. Proprietary hollow core floor slabs were tied to the beams by 2T25 tensile reinforcing bars, which also provide the in-plane continuity across the connections. The contribution of the floor strength and stiffness to the flexural capacity of the joint is currently neglected in the design process for precast concrete frames. The flexural strength of the connections in the double-sided tests was at least 0.93 times the predicted moment of resistance of the composite beam and slab. The secant stiffness of the connections ranged from 0.94 to 1.94 times the flexural stiffness of the attached beam. In general, the double-sided connections were found to be more suited to a semi-rigid design approach than the single sided ones. The behaviour of double sided bolted billet connection test results are presented in this paper. The behaviour of single sided bolted billet connection test results is the subject of another paper.

• Convergence Security Journal
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• v.19 no.2
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• pp.123-128
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• 2019

In March 2016, the Korean National Assembly passed the Counterterrorism Act called as "Counterterrorism Law for the Protection of the People and Public Safety", and relevant functions and roles of the counterterrorism institution were granted based on the law. However, a number of problems have been raised in the course of the job performance of the counterterrorism related institution, and various improvements have been discussed. This study conducted 'Analytic Hierarchy Process(AHP)' on the experts to identify the issues related to the improvement possibilities of the counterterrorism system that had been discussed previously. The results of the analysis to improve the current counterterrorism system are as follows. First, the priorities of the top factors were identified as in the order of legal institutions, cooperation, and operational aspect. Next, the priorities of the individual sub-factors were identified as the reorganization of the counterterrorism task force, the organic cooperation of domestic counterterrorism institution, and the cultivation of specialized human resources for anti-terrorism work. It was found that we should discuss the reorganization of counterterrorism institution as a policy consideration to improve the counterterrorism system.

• The Plant Pathology Journal
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• v.37 no.6
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• pp.619-631
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• 2021

Alfalfa mosaic virus (AMV), an economically important pathogen, is present worldwide with a very wide host range. This work reports for the first time the infection of Vinca minor and Wisteria sinensis with AMV using RNA sequencing and reverse transcription polymerase chain reaction confirmation. De novo assembly and annotating of contigs revealed that RNA1, RNA2, and RNA3 genomic fragments consist of 3,690, 2,636, and 2,057 nucleotides (nt) for IR-VM and 3,690, 2,594, and 2,057 nt for IR-WS. RNA1 and RNA3 segments of IR-VM and IR-WS closely resembled those of the Chinese isolate HZ, with 99.23-99.26% and 98.04-98.09% nt identity, respectively. Their RNA2 resembled that of Canadian isolate CaM and American isolate OH-2-2017, with 97.96-98.07% nt identity. The P2 gene revealed more nucleotide diversity compared with other genes. Genes in the AMV genome were under dominant negative selection during evolution, and the P1 and coat protein (CP) proteins were subject to the strongest and weakest purifying selection, respectively. In the population genetic analysis based on the CP gene sequences, all 107 AMV isolates fell into two main clades (A, B) and isolates of clade A were further divided into three groups with significant subpopulation differentiation. The results indicated moderate genetic variation within and no clear geographic or genetic structure between the studied populations, implying moderate gene flow can play an important role in differentiation and distribution of genetic diversity among populations. Several factors have shaped the genetic structure and diversity of AMV: selection, recombination/reassortment, gene flow, and random processes such as founder effects.

• Journal of Microbiology and Biotechnology
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• v.32 no.3
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• pp.365-377
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• 2022

Mammalian target of rapamycin (mTOR) is a serine-threonine kinase member of the cellular phosphatidylinositol 3-kinase (PI3K) pathway, which is involved in multiple biological functions by transcriptional and translational control. mTOR is a downstream mediator in the PI3K/Akt signaling pathway and plays a critical role in cell survival. In cancer, this pathway can be activated by membrane receptors, including the HER (or ErbB) family of growth factor receptors, the insulin-like growth factor receptor, and the estrogen receptor. In the present work, we congregated an electronic network of mTORC1 built on an assembly of data using natural language processing, consisting of 470 edges (activations/interactions and/or inhibitions) and 206 nodes representing genes/proteins, using the Cytoscape 3.6.0 editor and its plugins for analysis. The experimental design included the extraction of gene expression data related to five distinct types of cancers, namely, pancreatic ductal adenocarcinoma, hepatic cirrhosis, cervical cancer, glioblastoma, and anaplastic thyroid cancer from Gene Expression Omnibus (NCBI GEO) followed by pre-processing and normalization of the data using R & Bioconductor. ExprEssence plugin was used for network condensation to identify differentially expressed genes across the gene expression samples. Gene Ontology (GO) analysis was performed to find out the over-represented GO terms in the network. In addition, pathway enrichment and functional module analysis of the protein-protein interaction (PPI) network were also conducted. Our results indicated NOTCH1, NOTCH3, FLCN, SOD1, SOD2, NF1, and TLR4 as upregulated proteins in different cancer types highlighting their role in cancer progression. The MCODE analysis identified gene clusters for each cancer type with MYC, PCNA, PARP1, IDH1, FGF10, PTEN, and CCND1 as hub genes with high connectivity. MYC for cervical cancer, IDH1 for hepatic cirrhosis, MGMT for glioblastoma and CCND1 for anaplastic thyroid cancer were identified as genes with prognostic importance using survival analysis.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.4
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• pp.556-561
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• 2022

In this paper, we present a block media communication (BMC) system which employs powerline communication to the equipments used in the welding process for ship-assembly and uses metal block as a communication medium. Inductive couplers are installed on digital feeder and pin jig. Information signal is added to the current generated by the welding gun, and applied to the block. When the welding operation starts, information generated in the field is transmitted to the monitoring server in real-time. The field test on the BMC system confirms that the transmitted data are correctly received at the server. Since the proposed system can be built without any changes to the existing welding process, it is helpful to increase competitiveness of the shipbuilding industry through smart factory of shipyards. It is also possible to quickly respond to emergency situations that may occur to workers in an electromagnetic wave shielding environment or a closed space, the effect of preventing industrial accidents will be great.

• Journal of the Daesoon Academy of Sciences
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• v.34
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• pp.75-105
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• 2020

Previous scholars have studied Daesoon Jinrihoe mainly through its scriptures and doctrines; however, in this essay I have combined data from a questionnaire with interviews I conducted to observe women's religious engagement from their own perspectives. I conducted my fieldwork from October 23 to 26 at Yeoju Headquarters in Korea and received 81 questionnaire replies. This ongoing project will shed light on the niche for women in Korean new religious movements. This essay is divided into three parts. First, I reviewed 5 articles on general attitudes towards women within Daesoon Jinrihoe to serve as a doctrinal introduction. Second, I used the Ladies Club, the Women's Assembly of the Department of Social Welfare, and female students from the Inter- national Volunteers Association to better understand women's participation and education in Daesoon Jinrihoe on an institutional level. Third, I issued a questionnaire in order to learn respondents' sex, age, educational background, and birth place and used those data points determine patterns in how the above influence religious participation and positions in Daesoon Jinrihoe. My investigation showed that both the self-expectation and division of labor among the followers at Yeoju Headquarter were affected by and corresponded to social gender roles. Moreover, the emphasis on missionary work rather than centralized hierarchy contributed to a reduction in the influence of gender-segregation and led to relative coherence in terms of gender relations within Daesoon Jinrihoe.

• Nuclear Engineering and Technology
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• v.54 no.7
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• pp.2614-2624
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• 2022

Monte Carlo simulations were used to model a portable Neutron backscattering (NBT) sensor suitable for detecting plastic anti-personnel mines (APMs) buried in dry and moist soils. The model consists of a 100 MBq ²⁵²Cf source encapsulated in a neutron reflector/shield assembly and centered between two ³He detectors. Multi-parameter optimization was performed to investigate the efficiency of Be/Zr(BH₄)₄ and Be/Be(BH₄)₂ assemblies in terms of increasing the signal-to-background (S/B) ratio and reducing the total dose equivalent rate. The MCNP results showed that 2 cm Be/3 cm Zr(BH₄)₄ and 2 cm Be/3 cm Be(BH₄)₂ are the optimal configurations. However, due to portability requirements and abundance of Be, the ²⁵²Cf-2 cm Be/3 cm Be(BH₄)₂ NBT model was selected to scan the center of APM buried 3 cm deep in dry and moist soils. The selected NBT model has positively identified the APM with a S/B ratio of 886 for dry soils of 1 wt% hydrogen content and with S/B ratios of 615, 398, 86, and 12 for the moist soils containing 4, 6, 10, and 14 wt% hydrogen, respectively. The total dose equivalent rate reached 0.0031 mSv/h, suggesting a work load of 8 h/day for 806 days within the permissible annual dose limit of 20 mSv.

• Journal of the Korean Geosynthetics Society
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• v.20 no.4
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• pp.113-124
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• 2021

Underground environmental infrastructure and energy production facilities, which are recognized as avoidable facilities such as landfills, are emerging as an important social issue due to urbanization and economic growth. In order to safely construct a large-scale plant facility in the underground space, it is necessary to increase the utilization of the limited space layout and minimize unnecessary columns. In this study, the plant modularization method(Pipe Rack Module) was reviewed to solve the problems of work constraints, assembly and demolition, process system interconnection, and maintenance that occur when plant facilities are underground. In addition, plant module analysis was performed by applying various load conditions (earthquake load, device load, earth pressure load, etc.) to improve spatial layout usability and secure structure stability. Based on the analysis results under various boundary condition, the implications regarding the minimum installation interval and module arrangement (draft) of basic modules required for the construction of an underground combined plant were derived.

• Journal of Microbiology and Biotechnology
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• v.32 no.9
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• pp.1110-1119
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• 2022

Fe-S clusters are versatile and essential cofactors that participate in multiple and fundamental biological processes. In Escherichia coli, the biogenesis of these cofactors requires either the housekeeping Isc pathway, or the stress-induced Suf pathway which plays a general role under conditions of oxidative stress or iron limitation. In the present work, the Fe-S cluster assembly Isc and Suf systems of acidophilic Bacteria and Archaea, which thrive in highly oxidative environments, were studied. This analysis revealed that acidophilic microorganisms have a complete set of genes encoding for a single system (either Suf or Isc). In acidophilic Proteobacteria and Nitrospirae, a complete set of isc genes (iscRSUAX-hscBA-fdx), but not genes coding for the Suf system, was detected. The activity of the Isc system was studied in Leptospirillum sp. CF-1 (Nitrospirae). RT-PCR experiments showed that eight candidate genes were co-transcribed and conform the isc operon in this strain. Additionally, RT-qPCR assays showed that the expression of the iscS gene was significantly up-regulated in cells exposed to oxidative stress imposed by 260 mM Fe₂(SO₄)₃ for 1 h or iron starvation for 3 h. The activity of cysteine desulfurase (IscS) in CF-1 cell extracts was also upregulated under such conditions. Thus, the Isc system from Leptospirillum sp. CF-1 seems to play an active role in stressful environments. These results contribute to a better understanding of the distribution and role of Fe-S cluster protein biogenesis systems in organisms that thrive in extreme environmental conditions.