• 제목/요약/키워드: Arylboronic acid

검색결과 5건 처리시간 0.019초

Synthesis of Neopentyl Biphenylsulfonates Using the Suzuki-Miyaura Reaction

  • Cho, Chul-Hee;Kim, Chul-Bae;Sun, Myung-Chul;Park, Kwang-Yong
    • Bulletin of the Korean Chemical Society
    • /
    • 제24권11호
    • /
    • pp.1632-1636
    • /
    • 2003
  • Palladium-catalyzed cross-coupling reactions of neopentyloxysulfonylphenyl bromides with arylboronic acids provided a variety of neopentyl biphenylsulfonates in good yields. 2-Bromo- and 4-bromobenzenesulfonates underwent the coupling reaction more rapidly than 3-bromobenzenesulfonate, while chlorobenzenesulfonate did not produce the coupling product under the standard reaction conditions.

디아조크로마논과 보론산의 팔라듐 촉매하 결합반응을 이용한 Lespedezol $A_1$의 합성 (Formal Synthesis of Lespedezol $A_1$ via Versatile Palladium-Catalyzed Cross-Coupling of Diazochromanone with Arylboronic Acid)

  • 한영택
    • 약학회지
    • /
    • 제57권5호
    • /
    • pp.357-361
    • /
    • 2013
  • A formal synthesis of Lespedezol $A_1$ has been accomplished. The key feature of this synthesis involves an efficient and powerful palladium-catalyzed cross coupling reaction of diazocarbonyl compound with bis(benzyloxy)phenylboronic acid for the key 3-aryl-chromen-4-one intermediate, which was difficult to be prepared by Suzuki coupling reaction in the previous study. The versatile and efficient synthetic procedure would facilitate synthesis of pterocarpenes and their derivatives.