• International Journal of Heart Failure
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• v.6 no.1
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• pp.11-19
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• 2024

The prevalence of heart failure (HF) is increasing, necessitating accurate diagnosis and tailored treatment. The accumulation of clinical information from patients with HF generates big data, which poses challenges for traditional analytical methods. To address this, big data approaches and artificial intelligence (AI) have been developed that can effectively predict future observations and outcomes, enabling precise diagnoses and personalized treatments of patients with HF. Machine learning (ML) is a subfield of AI that allows computers to analyze data, find patterns, and make predictions without explicit instructions. ML can be supervised, unsupervised, or semi-supervised. Deep learning is a branch of ML that uses artificial neural networks with multiple layers to find complex patterns. These AI technologies have shown significant potential in various aspects of HF research, including diagnosis, outcome prediction, classification of HF phenotypes, and optimization of treatment strategies. In addition, integrating multiple data sources, such as electrocardiography, electronic health records, and imaging data, can enhance the diagnostic accuracy of AI algorithms. Currently, wearable devices and remote monitoring aided by AI enable the earlier detection of HF and improved patient care. This review focuses on the rationale behind utilizing AI in HF and explores its various applications.

• Proceedings of the Acoustical Society of Korea Conference
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• autumn
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• pp.131-134
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• 1999

This paper considers the acoustical characteristics of the mechanical valve employed in the Korean type Artificial Heart. $Bj\"{o}rk-Shiley$ tilting disc valve was chosen for the study and acoustic measurements were performed for the artificial heart operated in a mock circulation system as well as implanted to an animal as a Bi Ventricular Assist Device (BVAD). In the mock system, three different conditions of the valve were examined which were normal, damaged (torn off), pseudothrombus attached. Microphone measurements for the BVAD were carried out at a regular time interval for 5 days after the implantation operation. Of the recorded acoustic emissions from the artificial heart, click sounds mainly originated from the valves were further analyzed using Multiple Signal Classification (MUSIC) for estimating their spectral properties. It was shown that the spectral peaks below 4 kHz and the optimal order number for MUSIC, equivalent to the number of the spectral component, might be the key parameters which were highly correlated to the physiological states of the valve like the mechanical damage of the valve or the formation of thrombus on the valves.

• Journal of Chest Surgery
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• v.28 no.6
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• pp.533-541
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• 1995

We recently developed a new model of moving actuator type totally implantable artificial heart[TIAH , based on the reverse position of the aortic and pulmonary conduits. This concept was proposed by one of surgeons in our team[Joon-Ryang Rho, M.D. to facilitate anatomical fitting of TIAHs. The moving actuator type electromechanical TIAH consisted of the left and right blood sacs, and the moving actuator including a motor. The inverted umbrella type polyurethane valves were used in the blood pumps. The aortic conduit was positioned anterior to the pulmonary conduit, which was the opposite relation to the conventional configuration of other total artificial hearts. We also adapted slip-in connectors for the aortic and pulmonary conduits. Two sheep , weighing 60-69 kg, were used for implantation. After small cervical incision and trans-sternal bilateral thoracotomy, cardiopulmonary bypass [CPB was administered using an American Optical 5-head pump and a membrane oxygenator[Univox-IC, Bentley . The anterior and posterior vena cavae were drained separately for venous return. An arterial return cannula was inserted into the right common carotid artery. During CPB, almost all of the ventricular myocardium was excised down to the atrioventricular groove and the artificial heart was implanted. We achieved 3-day survival in the first sheep and 2-day survival in the second. The day after operation the first sheep was successfully extubated and the second sheep was weaned from a respirator with good condition. After extubation, the first sheep walked around in the cage and fed herself. Serial laboratory and hemodynamic examinations were done during the experiments. In both sheep, pulmonary dysfunction was gradually developed, which was accompanied by acute renal failure. The animals were sacrificed and autopsy was done. Unexpected pregnnacy was incidentally found in both sheep. To our knowledge this is the first report of significant survival cases in the orthotopic implantation of electric TIAH using sheep.

• Proceedings of the KTCVS Conference
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• 1993.06a
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• pp.128-128
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• 1993

• Journal of the Korean Society of Visualization
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• v.4 no.1
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• pp.47-55
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• 2006

The left ventricular filling flow is now considered as an indicator which can be used for early diagnosing of cardiovascular diseases. Because the understanding of left ventricular flow physics is critical for this purpose, the downstream flow characteristics of the artificial heart valve are investigated using particle image velocimetry (PIV) method. In this study, we investigated the wake characteristics of flows passing through three different artificial valves (St.Jude medical bileaflet mechanical valve. Bjork-Shiley monostrut mechanical valve and St.Jude medical Biocor bio valve). The downstream flow field has remarkably altered according to the different valves. SJM MHV has the flow field similar to the pulsating circular jet and BS MHV has oblique pulsating jet. SJM BHV shows the similar flow field of clinical data of normal heart.

• Journal of Biomedical Engineering Research
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• v.19 no.3
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• pp.291-296
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• 1998

A new mechanical heart valve prosthesis has been designed appling systematic design methodology. The function of the heart valve was defined, and search for design variation has been carried out according to the functional structure, Optimal model among the various variations was determined in view of the design specificationn. Proto type valve was fabricated and test has been carried out using a mock circulation system. It has been observed that the pressure profile, cardiac output and behavior characteristics are generally satisfactory.

• 제어로봇시스템학회:학술대회논문집
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• 1988.10b
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• pp.858-863
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• 1988

A micro-processor based control system for a brushless DC motor used in the motor-driven electromechanical total artificial heart was developed. Functionally, the control system is composed of two parts. The first part is the velocity and position controller to assure that the motor follows a predetermined optimal velocity profile with minimal energy consumption, and to guarantee the full stroke length. This part also utilize the passive adaptive control method to be robust against the load disturbance, system parameter variation, and uncertainty which is the environment of artificial heart system. The pump output control is the second part, and this part provides the required responses of the artificial heart to the time-varying physiologic demands. The basic requirements of these responses are preload sensitivity, afterload insensitivity, and the balanced ventricular outputs. The performance and reliability of this control system was evaluated through a series of mock circulation tests and animal implantation, and the results are very encouraging.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2001.04a
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• pp.748-751
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• 2001

Monoleaflet polymer artificial heart valve was known to show remarkable improvement in antithrombosis and pressure drop compared with other type of artificial valve. In this investigation monoleaflet the vertical and horizontal deflection pattern of polymer heart valve with three types of supporting members straight member, and two curved members was analysed using the large deformation nonlinear finite element method.

• Transactions of the Korean Society of Mechanical Engineers
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• v.15 no.3
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• pp.855-868
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• 1991

본 연구에서는 위에서 언급한바와 같은 제반사항들에 대해 이론적인 해석을 행하고, 그 결과를 이용하여 설계된 모델이 생체내에 이식될 수 있는 가능성의 여부를 판단하며 생체내에 이식 되었을 때의 성능과 생체에 미치는 영향등을 예측하고자 한다.

• Proceedings of the KAIS Fall Conference
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• 2003.06a
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• pp.288-290
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• 2003

Artificial heart is divided by pulsation flow type and continuous flow type according to blood circulation pattern. Axial flow blood pump is a kind of continuous flow type artificial heart. Axial flow blood pump would be different pump performance according to impeller's shape and rotating velocity. Pump performance be able to compare by flow rate according to differential pressure and Impeller's rotating velocity. It confirms Impeller model of better efficiency according to compare Pump performance of axial flow blood pump using CFD with actual experiment result.