• Title/Summary/Keyword: Approval standard

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The Relationships of the Opioid-peptides to Hope of the Cancer Patients (암환자에서 희망과 아편양 펩타이드의 관련성 연구)

  • Kim, Dal-Sook
    • Asian Oncology Nursing
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    • v.1 no.2
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    • pp.157-167
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    • 2001
  • Purpose : This study was 1) to determine the relationship between endogenous opioid-peptides and hope 2) to evaluate the availability of the opioid- peptides, known as biochemicals of emotion in psychoneuroimmunology, as a variable to explain hope. Method : blood sampling for 20 cancer patients' (age range 18-73, 13 men and 7 women, having mild pain or no pain, can do ADL) were made under approval from the doctors in a university hospital at 8 A.M. and quantitative analysis of opioid peptides were done by the internal standard method. In 10min after blood sampling, hope was measured using Kim and Lee's hope scale which had acceptable reliabilities and validity after making consent about interviewing. Blood was sampled from the seven normal adults for comparing the degrees of the opioids. None-parametric statistical analysis was used. Results : There was a significant difference in leucine enkephalin between normal adults and cancer patients. And significant positive relationship existed between chemotherapy and leucine enkephalin. So, the relationships between hope and the endogenous opioids in the patients before chemotherapy were re-tested, excluding the effect of chemotherapy on opioids. As a result, a significant negative relationship between hope and beta- endorphin(r=-.841<.05) showed. And there were highly negative relationships between leucine enkephalin and methionine enkephalin and hope, but not significant statistically. Conclusions : This results implies endogenous opioids can be used as a biological variable to explain hope. More researches in sophisticated design would be needed ,especially in human model.

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Recent Advances in Diagnosis and Treatment of Alzheimer's Disease (알츠하이머병의 최신지견)

  • Lee, Jung Jae;Lee, Seok Bum
    • Korean Journal of Biological Psychiatry
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    • v.23 no.2
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    • pp.48-56
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    • 2016
  • Alzheimer's disease (AD) is a neurodegenerative disorder in which neuronal loss causes cognitive decline and other neuropsychiatric problems. It can be diagnosed based on history, examination, and appropriate objective assessments, using standard criteria such as the Diagnostic and Statistical Manual of Mental Disorders or the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA). Brain imaging and biomarkers are making progress in the differential diagnoses among the different disorders. The cholinesterase inhibitors, donepezil, rivastigmine and galantamine and N-methyl-D-aspartate receptors antagonist memantine are approved by the US Food and Drug Administration for AD. Recently some acetylcholinesterase inhibitors gained approval for the treatment of severe AD and became available in a higher dose formulation or a patch formulation. Optimal care in AD is multifactorial and it should include early diagnosis and multidisciplinary care with pharmacological and nonpharmacological interventions including exercise interventions, cognitive interventions and maintenance of social networks.

A Study on the Application of Operational Experience in the Stage of Aircraft System Design and Safety Assessment (항공기 시스템 설계와 안전성평가에 운영경험 반영 사례 연구)

  • Koo, Min-Sung
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.22 no.2
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    • pp.34-39
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    • 2014
  • Airworthiness authorities specify the technical standards of airworthiness that propose minimum requirement of the commercial transport category and apply the rules in the certification process to ensure the safety of the aircraft. The Federal Aviation Administration and other national airworthiness authorities define the fatal accident risk levels for the safety assessment of the aircraft system and establish standard procedures to apply both qualitative and quantitative analysis techniques. However, an accident or incident may occur by the combination of various factors, although the aircraft is designed in accordance with the strict standards and approval by the Airworthiness Authorities. There are some key factors, such as human error, unpredictable complex system failures, degradation of the components reliability, improper maintenance task and intervals. Risk can be reduced by reflecting aircraft operational experience with similar types of aircraft in the process of aircraft development and safety assessment. Result of the root cause analysis for the Airbus A300-600 incident in which the aircraft engine reverser was deployed in the air have been introduced to reflect the design of system and related components. Also, this paper suggests to create a big-database in order to provide a feed-back to the FAR Part 25 transport category design and safety assessment of the operational experience.

A Study on the Evaluation of the Law School Libraries (법학전문도서관 평가에 관한 연구)

  • Kim, Won-Man;Lee, Jee-Yeon
    • Journal of the Korean Society for information Management
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    • v.27 no.1
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    • pp.165-183
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    • 2010
  • This study investigated factors and issues for law school library evaluation. Also, this study suggested the roles and guidelines for law school libraries to perform its own role and function. To carry out the research, surveys were conducted with the law librarians. Then surveys were conducted to investigate law school students' demands and behaviors. Especially this study evaluated law libraries which were not carried out independently and professionally until now and meaningful as it thoroughly investigated users' demands and behavior with law school libraries and function and roles of law librarians. To facilitate law school library services and functions, quality of the collections, librarians' role, and users' needs should be considered as well as buildings and physical facilities. Particularly, users' needs assessment and librarians' opinion survey will be imperative in implementing evaluation.

The Selection and Effects of Contract Language in International Contract (국제계약에 있어서 계약언어의 선택과 효과)

  • Song Yang-Ho
    • Journal of Arbitration Studies
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    • v.15 no.1
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    • pp.207-228
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    • 2005
  • When closing an international contract, both contract parties endeavor to convey their intentions from the stage of negotiation to the moment of signing the contract. Of the many problems presently related to contract language, the first one to consider is which contract party will run the risk of the language deficiencies occurring as a result of the misunderstanding and misinterpretation between different languages. The second problem to consider is whether the interpretation and translation of the contract language is needed and, if so, which party is going to bear the expenses and assume responsibility of the misinterpretation in the translation of, the contract language. The third problem is related to the obligation of explaining to both contract parties the contents and details of the international contract written in different languages. The fourth issue is which language of both contract parties becomes the standard contract language in the procedure of arbitration. The fifth, but not the last problem, is how to solve the language defects in interpreting and translating the contract languages. These five problems can be easily solved by the approval of the contract parties in scrutinizing and selecting the contract languages. However, this research mainly focuses on which effects of the contract language and as how to define and select the contract language.

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A Study on Certification Methods due to Scope and Influence of Design Changes for the Aircraft (항공기 설계변경의 범위 및 영향성에 따른 안전성 인증방법에 관한 고찰)

  • Lee, Kang-Yi;Ko, Joon Soo
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.45 no.7
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    • pp.566-573
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    • 2017
  • A type certificate is required to ensure the safety of aircraft design. If a person is to pursue major design change to the certified aircraft, an applicant has to apply for a new type certificate, an amended type certificate, or a supplemental type certificate appropriately. Design changes to be applied for a supplemental type certificate are abstractly defined in ICAO, FAA, and EASA regulations. In this paper, authors reviewed certification procedures regarding design changes, analysed certification examples of leading countries, and presented the criteria to determine "major design changes not extensive" for a supplemental type certificate.

A Study on the Analysis and Improvement methods of Emergency Medical Service Systems for Large Scaled Fire (대형화재에 대비한 응급의료체계에 관한 분석과 개선방안)

  • Lee, Maria
    • The Korean Journal of Emergency Medical Services
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    • v.11 no.1
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    • pp.41-52
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    • 2007
  • In Korea, Crowds, as well as more complex and larger structures, have been caused more victims in the event of fire. In that situation, EMSS should have done triage the patients according to their severity in the field, treat with standard guidelines as like advanced burn life support and transfer to appropriate facility. But in many cases, they didn't practice like that. The purpose of this study is to give basic data for proper emergency medical services by analysing EMSS of large scaled fire in Korea and suggesting some improvement methods. The improvment methods are like this ; First, developing of protocols about burn patient is needed for EMT and dispatcher. Second, Legal approval for advanced treatment is needed for EMT. Third, Fire-helicoptors are needed in Daejeon and Jeju. And Emergency Medical Helicoptors are needed in EMSS. Forth, more advanced emergency medical centers of burn must be established. Sixth, more pocket-mask and burn sheet are needed for 119 rescuer. Finally, building owners must change inflammable materials as non-inflammable materials and educate fire-prevention and first-aid to employees.

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A Study on the Business Plan Changes of Housing Complex evaluated by the "Housing Performance Grading Indication System" (주택성능등급표시제도의 개선을 위한 인정 단지의 사업계획변경 현황에 대한 실태조사 연구)

  • Lee, Sung-Ok;Bae, Cheol-Hak
    • KIEAE Journal
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    • v.11 no.6
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    • pp.43-51
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    • 2011
  • This study aims to analyze on the change status in the project plan of the housing complex as evaluated through the Housing Performance Grading Indication System. This a a system for assessing quantitatively the comprehensive, unified performance of housing by an objective standard from the design stage since January 9, 2006. As housing is a composite with various performances, it is required necessary to objectively assess the various performances from the design stage for building better housing. Thus, this study analyzed the change status and objectively described objectively it centering on the construction and structure drawings for 12 items posted in the Facility Management System_(FMS) out of examples recognized by 2011 since the implementation of the system. The changes were analyzed though observing each performance item-specific characteristics and confirming the books approved for use. In various parts, such as the site area, landscape plan, plane plan for unit, supplementary welfare facility plan, finishing materials, window size and location, the project plan was changed. These changes may result in a grading change in of the performance items of the system. This study purpose is for it to be used as a basic resource required for future system development by supplementing the limitation of the design phase and then through playing a basic role for the assessment after completion.

A Study on the Effective Method of Fire Extinguisher Maintenance In the Underground Parking Lot of the Apartment (아파트 지하주차장 소화기의 유지관리 효율화 방안에 관한 연구)

  • Lee, Young-Sam
    • Journal of the Korea Safety Management & Science
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    • v.18 no.3
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    • pp.1-8
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    • 2016
  • The definition of an apartment is a building more than 5 stories high and which is the standard law. Currently, the number of apartments is increasing much faster than detached houses. Owning an apartment is a normal trend these days. However, the increasing number of apartments has been increasing the number of apartment fires which also has been making social problems. Therefore, this study was conducted for the fire extinguisher among other fire facilities because it is important for initial fire suppression. The research subject is on the fire extinguisher that is in the underground parking lot of 40 apartment complexes which are more than 10 stories. Survey and analysis were conducted for 80 fire extinguishers. There are two fire extinguishers for each apartment. The result of this study is that all installed fire extinguishers are ABC dry chemical type, 92% of them is 3.3kg and that meet the legal height(less than 1.5m). However, the condition such as appearance, inspection, manufactured year, appearance of signs, material of signs, size of signs, etc. was insufficiency. So improvement of law and system that are fire facility construction, maintenance implementation and additional designation of type approval about sign will be needed in my opinion.

Analysis of the Response Time of a Photoelectric Spot-Type Smoke Detector Depending on the Type of Fires (화원에 따른 광전식 연기감지기 반응시간 분석)

  • Jee, Seung-Wook
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.27 no.5
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    • pp.89-94
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    • 2013
  • The fire testing performed for smoke detector model approval in Korea tests only one kind of fire smoke. A photoelectric spot-type smoke detector using Mie scattering is affected by the wavelength of light beam and the particle diameter. According to UL (Underwriters Laboratories Inc.) 268 standard, this paper analyze the characteristic of the response for a photoelectric spot-type smoke detector on sale in Korea using various fire smokes. Probability that the response time is included in non-defective range is 100% in paper fire, 90% in wood fire and 75% in flammable liquid fire, 90% in wood fire and 75% in flammable liquid fire. According to the estimation for population mean of the response time choosing a confidence level of 99%, a maximum of 19% for wood fire and that of 38% for flammable liquid fire are defective. As the result of analysis of smoke particle, this paper is found that these results are caused by the smoke particles are wide variations in size or have very black.