• 제목/요약/키워드: Appropriate

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Selection of appropriate biomatrices for studies of chronic stress in animals: a review

  • Mohammad, Ataallahi;Jalil Ghassemi, Nejad;Kyu-Hyun, Park
    • Journal of Animal Science and Technology
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    • 제64권4호
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    • pp.621-639
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    • 2022
  • Cortisol and corticosterone, hormones traditionally considered biomarkers of stress, can be measured in fluid biomatrices (e.g., blood, saliva) from live animals to evaluate conditions at sampling time, or in solid biomatrices (e.g., hair, feather) from live or dead animals to obtain information regarding long-term changes. Using these biomarkers to evaluate physiological stress responses in domestic animals may be challenging due to the diverse characteristics of biomatrices for potential measurement. Ideally, a single measurement from the biomatrix should be sufficient for evaluating chronic stress. The availability of appropriate and cost-effective immunoassay methods for detecting the biomarkers should also be considered. This review discusses the strengths and limitations of different biomatrices with regard to ensuring the highest possible reliability for chronic stress evaluation. Overall, solid biomatrices require less frequent sampling than other biomatrices, resulting in greater time- and cost-effectiveness, greater ease of use, and fewer errors. The multiplex immunoassay can be used to analyze interactions and correlations between cortisol and other stress biomarkers in the same biomatrix. In light of the lack of information regarding appropriate biomatrices for measuring chronic stress, this review may help investigators set experimental conditions or design biological research.

통기밴드식 건조기의 성능 평가 실험 장치 (Lab-scale experimental setup to evaluate the performance of band driers)

  • 박성민;오상현;김성일;김원정
    • 한국가시화정보학회지
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    • 제20권3호
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    • pp.36-41
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    • 2022
  • Drying process is involved in the production of various products including food, textiles, paper, pharmaceuticals, and batteries. Phase change of liquid to vapor generally requires enormous thermal energy, so in order to save energy, it is advantageous to develop an appropriate drier and use it under appropriate operating conditions, depending on the characteristics of materials. However, due to the complex, multiscale heat and mass transfer occurring during drying processes, predictions of appropriate drying conditions before actual operation are not easily achieved, leading to challenges in designing driers. Here, we developed a lab-scale experimental setup to evaluate the performance of band dries. The experimental setup was used to measure the moisture content and temperature change in the materials being dried in a belt dryer. Experimental results obtained using our lab-scale setup allow us to predict the performance of a full-scale band drier, thus suggesting a practical framework for predicting the drying process of various materials and developing band driers.

고소 작업용 섬유로프의 고정 매듭법에 따른 강도 변화의 해석 및 실험적 연구 (Analysis and Experimental Study of Strength Change according to Fixed Knot Method of Fiber Rope for High Altitude Work)

  • 송상민;김민섭;신대용;임사혁;권오헌;박우림
    • 한국안전학회지
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    • 제37권3호
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    • pp.1-8
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    • 2022
  • Workplace accidents are common while working at elevations. Thus, various safety measures such as safety handrails and horizontal safety nets are implemented to prevent falls. The minimum safety measure is the lifeline installation. However, because its standards have not been clearly established, it is often misused, resulting in inappropriate knot methods that increase the chance of accidents while working at elevations. Therefore, clarifying the appropriate usage methods or criteria for the various lifelines is required in the field. This study proposed an appropriate installation method by experimentally and numerically evaluating the change in strength according to the fixed knot lifeline method. In addition, three knot methods were specified for each material. The results obtained are expected to contribute to lessening falls through the establishment of lifeline installation standards and the development of appropriate parts.

국가부채의 재정위기 현황과 감당수준 (National Liability and Fiscal Crisis)

  • 정도진
    • 아태비즈니스연구
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    • 제12권4호
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    • pp.253-270
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    • 2021
  • Purpose - The main purpose of this study is to measure and evaluate the level of national liabilities that Korea's national finances can afford. Specifically, the concepts of national debt and national liability are clarified, and the appropriate level of national liabilities is measured in terms of short-term fiscal crisis, mid-to-long-term fiscal crisis, and GDP. Based on these measurements of fiscal crisis, this study would like to propose national fiscal management plans. Design/methodology/approach - In order to clearly recognize the difference between the national debt and the national liability, this study examines the data from 2013 to 2020. In addition, this study uses data from the national financial statements from 2013 to 2018 to measure the appropriate level of national liabilities in terms of fiscal crisis management. Findings - Short-term fiscal crises, measured by current ratios, will not occur. Nevertheless, in view of the cash flow compensation ratio, the short-term bankruptcy of the national finances of Korea depends on the re-borrowing of short-term borrowings and current and long-term borrowings. In addition, in order to manage the mid-to long-term financial crisis, it is necessary to pay attention to the liability growth rate rather than the liability size. Research implications or Originality - While previous studies focused on the appropriate level of national debt, this study was differentiated as a study focused on the level of national liability coverage. It is expected that the results of this study will be used to manage the national fiscal soundness.

A Study on the Prevention of Appropriate Store and Gentrification to Restore the Function of the Commercial District in the Original City

  • RYU, Tae-Chang
    • 유통과학연구
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    • 제20권11호
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    • pp.109-120
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    • 2022
  • Purpose: We would like to identify the appropriate size of stores in the commercial district suitable for the era of low growth. In addition, it is intended to present alternatives to prevent gentrification along with measures to revitalize commercial districts according to the selection of appropriate stores. Research design, data and methodology: The importance and commercial district usage patterns were identified through surveys by consumers and sellers. the demand and size of the commercial area were calculated based on the floating population and resident registration population. In addition, based on this, through metric analysis, the importance of the business district activation plan and what important matters can prevent gentrification were analyzed. Result: In this the study, 555 stores are currently operating in the target area, but it is seen as a commercial district with a scale that can operate 136 stores and 938 stores. In addition, it was analyzed that the Commercial Lease Protection Act needs to be strengthened to prevent gentrification. Conclusions: Due to the nature of small and medium-sized cities in Korea, commercial districts that have once lost their resilience must take much effort to find vitality. It is believed that local commercial districts will have resilience when diagnosis and recovery measures are adequately presented.

IDENTIFICATION OF SIGNIFICANT CRITERIA FOR SELECTION OF CONSTRUCTION PROJECT MANAGERS IN IRAN

  • Abbas Rashidi;Fateme Jazebi;Mohamad Hassan Sebt
    • 국제학술발표논문집
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    • The 3th International Conference on Construction Engineering and Project Management
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    • pp.1564-1569
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    • 2009
  • Project managers play a key role in cost, time, and quality of a project. Selection of an appropriate project manager, therefore, is considered as one of the most important decisions in any construction project. It should be noted that most important decision makings are carried out by the project manager throughout the project. Traditionally, project manager selection in construction companies in Iran is through organizing an interview with candidates and selecting the most appropriate choice in accordance with the capabilities, potentials and individual specifications coupled with the requirements of the project. In the same direction, organizing interview on selection of appropriate candidate is usually carried out by senior managers of companies. Determination of the most important criteria for selection of project managers and also identification of significance coefficient of each criterion can highly help senior managers of companies to make sound selection decisions. In this paper, a numerical model has been considered for determination of significance of each criterion, details of which are submitted for selection of project manager in Iranian petrochemical, oil and gas sector companies. For this reason, all criteria- considered by senior managers of the companies under study- are first determined. Then, information obtained through 38 interviews, conducted by senior managers of the mentioned companies while selecting project manager, is analyzed. Significant coefficient of each criterion is calculated through the accumulated data using fuzzy curves method.

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TECHNICAL PROPOSAL BASED COST REDUCTION BIDDING SYSTEM FOR SUPPLYING AFFODABLE HOUSING

  • Seunghee Kang;Jeongseok Lee;Gunhee Cho;Jeongrak Sohn;Jongdae Bang
    • 국제학술발표논문집
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    • The 3th International Conference on Construction Engineering and Project Management
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    • pp.1433-1439
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    • 2009
  • Best value is the ultimate goal of the owner and can thus have diverse meanings according to the project characteristic, owner's purpose, user groups' payment capability, etc.. Recently, resettlement problems of the marginalized members in the urban regeneration area have been issued in Korea because they have no capability to purchase (or lease) redeveloped housing (or apartment). It means that a minimized production cost for reducing supply price of housing is a key factor in establishing the best value of the marginalized members. The lowest-price bidding system serves the purpose of ensuring a minimized production cost, but due to the low-cost investments, it creates various problems, such as sloppy construction, lowered quality, an increased LCC, and worsening profitability for builders. Thus, to help them resettle, it is necessary to supply affordable housing geared towards a certain appropriate quality and minimum construction costs. Towards this end, this study aimed to propose a cost reduction bidding system based on a technical proposal. The proposed technical-proposal-based cost reduction bidding system consists of the following components: work-unit-based, project-unit-based, and construction-period-reducing technical proposals. These components are evaluated to select the best bidder for a given project. The technical proposal based cost reduction bidding system proposed herein is expected to provide facilities with appropriate supply prices and appropriate quality levels, to bolster the technological competitiveness of builders.

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Long-term management of Graves disease: a narrative review

  • Hyo-Jeong Kim
    • Journal of Yeungnam Medical Science
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    • 제40권1호
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    • pp.12-22
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    • 2023
  • Graves disease (GD) is the most common cause of hyperthyroidism, accounting for more than 90% of cases in Korea. Patients with GD are treated with any of the following: antithyroid drugs (ATDs), radioactive iodine (RAI) therapy, or thyroidectomy. Most patients begin treatment with ATDs, and clinical guidelines suggest that the appropriate treatment period is 12 to 18 months. While RAI treatment and surgery manage thyrotoxicosis by destroying or removing thyroid tissue, ATDs control thyrotoxicosis by inhibiting thyroid hormone synthesis and preserving the thyroid gland. Although ATDs efficiently control thyrotoxicosis symptoms, they do not correct the main etiology of GD; therefore, frequent relapses can follow. Recently, a large amount of data has been collected on long-term ATDs for GD, and low-dose methimazole (MMZ) is expected to be a good option for remission. For the long-term management of recurrent GD, it is important to induce remission by evaluating the patient's drug response, stopping ATDs at an appropriate time, and actively switching to surgery or RAI therapy, if indicated. Continuing drug treatment for an extended time is now encouraged in patients with a high possibility of remission with low-dose MMZ. It is also important to pay attention to the quality of life of the patients. This review aimed to summarize the appropriate treatment methods and timing of treatment transition in patients who relapsed several times while receiving treatment for GD.

골절부 변형률에 따른 골절부 가골 형성 과정의 유한요소해석 (Finite element analysis of callus generation in fractured bones according to the strain distribution)

  • 김석훈;박명길;안송도;조성겸;장승환
    • Composites Research
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    • 제22권3호
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    • pp.29-34
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    • 2009
  • 본 논문에서는 유한요소해석을 이용하여 경극 골절부의 변형률 분포를 계산하였다. 16주에 걸친 골절 회복기간 동안 최적의 가골 형성의 조건을 찾기 위해 스테인리스 강 고정판과 다양한 적층순서를 가지는 복합재료 고정판이 고려되었다. 이 연구를 통해 골절부 가골 형성을 촉진하는 $2{\sim}10%$ 변형률을 유발하는 최적 하중 조건을 계산하였다. 해석결과로부터 복합재료 고정판의 경우 최적의 변형률을 가지게 하는 하중조건은 스테인리스 강 고정판의 경우보다 낮았으며, 응력방패 현상을 감소시켜 골절치료에 유리함을 가지는 것을 알 수 있었다.

Determination of safe levels and toxic levels for feed hazardous materials in broiler chickens: a review

  • Jong Hyuk Kim
    • Journal of Animal Science and Technology
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    • 제65권3호
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    • pp.490-510
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    • 2023
  • Feed safety is needed to produce and provide safe animal feeds for consumers, animals, and the environment. Although feed safety regulations have been set for each country, there is a lack of clear feed safety regulations for each livestock. Feed safety regulations are mainly focused on heavy metals, mycotoxins, and pesticides. Each country has different safe levels of hazardous materials in diets. Safe levels of hazardous materials in diets are mostly set for mixed diets of general livestock. Although there is a difference in the metabolism of toxic materials among animals, the safe level of feed is not specific for individual animals. Therefore, standardized animal testing methods and toxicity studies for each animal are needed to determine the correct safe and toxic levels of hazardous materials in diets. If this goal is achieved, it will be possible to improve livestock productivity, health, and product safety by establishing appropriate feed safety regulations. It will also provide an opportunity to secure consumer confidence in feed and livestock products. Therefore, it is necessary to establish a scientific feed safety evaluation system suitable for each country's environment. The chance of outbreaks of new hazardous materials is increasing. Thus, to set up appropriate toxic levels or safe levels in feed, various toxicity methods have been used to determine toxic levels of hazardous materials for humans and animals. Appropriate toxic testing methods should be developed and used to accurately set up and identify toxicity and safe levels in food and feed.