• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1999년도 춘계학술대회
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• pp.1-4
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• 1999

The potential therapeutic benefit of nicotinic ligands in a variety of neurodegenerative pathologies involving the CNS has energized research efforts to develop nicotinic acetylcholine receptor (nAChR) subtype-selective ligands. In particular, there has been a concerted effort to develop nicotinic compounds with selectivity for CNS nAChRs as potential pharmacological tools in the management of these disorders. The characterization of other novel nicotinic ligands such as epibatidine. showing a marked increase in potency at nAChRs, has provided additional support for the development of potent, selective ligands at individual nAChR subtypes. We have developed and studied a number of nicotinic compounds to identify potential candidates exhibiting such selectivity. In the present study, we report the synthesis and biological evaluations of some azabicyclic and azatricyclic nicotine analogs to decipher the relationship among steric requirements of the nicotine's pyrrolidine ring system, binding affinity and subtype-selectivity.

• 응용통계연구
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• 제30권1호
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• pp.159-167
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• 2017

일반적으로 잠재적 이상치군은 검정과정을 통해 최종적으로 이상치 여부를 판단하지만 검정절차를 생략하거나 모의실험에 의해 계산된 유의값을 기반으로 검정을 수행하는 이상치 탐지법들도 있다. 본 논문에서는 가면화나 수렁화현상을 피하기 위하여 이상치후보군에 속한 개별 관찰치를 검정하지 않고 이상치후보군의 부분집합들을 검정하는 절차를 제안한다. 제안된 방법의 활용을 보여주는 예제와 다른 방법과의 검정력 비교를 위한 모의실험 결과가 제시된다.

• 한국식품과학회지
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• 제52권6호
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• pp.627-631
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• 2020

High amounts of lemon seeds are discarded as by-products of processing industries. It is important to find some measures, whereby they could be used in value-added ways. Although few studies have been conducted on lemon seed oils, no study has been conducted on the nutrient content of lemon seed sprouts. The objective of this study was to investigate the nutritional value and antioxidant potential of lemon seeds and sprouts. The 1,1-diphenly-2-picrylhydrazyl radical-scavenging potential, total polyphenol, and total free amino acid content were higher in the sprouts than in the seeds. Similarly, the content of such mineral elements as Fe, Na, and Zn, increased with germination. However, salicylic acid and total mineral content were lower in the sprouts than in the seeds. The results indicate that lemon seeds and sprouts could be regarded as high-value materials in food and cosmetic industries.

• 한국농공학회논문집
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• 제50권3호
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• pp.91-104
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• 2008

This study developed the WSM (weighted scenario method)-AHP method that can optimize the weighting value for multi-criteria to make GIS grid-based potential surface. The potential surface has been used to simulate urban expansion using distributed cellular automata model and to generate land-use planning as basic data. This study formulated the WSM-AHP method in mathematically and applied to test region, Suwon city, which located on south area from Seoul. WSM-AHP method generates potential map for each pair of weighting value for all criteria, which one criterion is weighted with high weighting value and the others use low weighting value, considering that the summation for all criteria weighting values should be "1". The potential change rate to the step of weighted scenario for weighting value of criteria is standardized like AHP intensity matrix in this study. From the standard potential change rate, WSM-AHP intensity matrix is completed, and then the optimal weighting value is calculated from the maximum eigenvector of the WSM-AHP matrix, according to the new WSM-AHP method developed in this study. The applied results of new method showed that the optimal weighting value from WSM-AHP is more resonable than the general AHP specialists' evaluation for weighting value. The another new finding of this study is to suggest the deterministic approach to optimize the weighting value for the distributed CA model, which is used to find new city area and to generate rational land-use planning.

• 농촌계획
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• 제10권3호
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• pp.41-51
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• 2004

This study aims to develop a potential evaluation method for urban spatial expansion using remote sensing (RS) and geographic information system (GIS). A multi-criteria evaluation method with several criteria and their weighting values was introduced to evaluate the score and quantification of the potential surface around the existing cities. The six criteria with one geographic factor, slope, and five accessibility factors, time distance from center of the city, national road, interchange of expressway, a big city, and station, were defined for the potential. RS techniques were applied for classification of the actual urban expansion maps between two periods, and GIS functions were used for score of accessibility criteria with a distance decay function from geographic, road and several point maps, which was developed in this study. The new methodology was applied to a test area, Suwon, between 1986 and 1996. In order to optimize the six weighting values, this study made new findings to search the optimal combination of the weighting values from new methodology, weighted scenario method for intensity order (WSM), combined with intensity order and AHP method, including a trial and error method for sensitivity analysis to make the intensity order. The optimal combination of the weighting values by the new method generated the optimal potential surface, considering spatial trend of urban expansion in the test area.

• 전기화학회지
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• 제1권1호
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• pp.8-13
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• 1998

This work presents the way how to evaluate the degree of reversibility of the discharging process undergone by the nickel hydroxide film cathodically deposited on pure nickel as a positive electrode for electrochemical capacitor using the combined cyclic voltammetry and potential drop method, supplemented by galvanostatic discharge and open-circuit potential transient methods. The time interval necessary just to establish the current reversal of anodic to cathodic direction from the moment just after applying the potential inversion of anodic to cathodic direction, was obtained on cyclic voltammogram. The cathodic charge density passed upon dropping the applied potential, was calculated on potentiostatic current density-time curve. Both the time interval and the cathodic charge density in magnitude can be regarded as being measures of the degree of reversibility of the discharging process undergone by the positive active material for supercapacitor, i.e. , the longer the time interval is, the lower is the degree of reversibility and the greater the cathodic charge density is, the higher is the degree of reversibility. From the applied potential dependences of the time interval and cathodic charge density, discharge at $0.42 V_{SCE}$ was determined to be the most reversible.

• 농촌계획
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• 제26권2호
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• pp.25-37
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• 2020

The aim of this study is to assess the potential for fusion and convergence in industrial agriculture. First, we analyzed the types of industrial agriculture and applied the agri-business and ICT agriculture. After then, we analyzed the Project Potential Index (PPI) of the agri-business and ICT agriculture using the agricultural enterprise database provided from Rural Research Institute in Korea. The results revealed that Haenam have a high potential for agri-business project because of large number of farmers and annual sales. Wanju was considered as the suitable place for ICT agriculture project because of large area of greenhouse. This study was applied only 7 study area but the methodology suggested in this study could be widely used for assessing potential project various types of industrial agriculture.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2023년도 춘계학술대회
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• pp.86-86
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• 2023

• 자원리싸이클링
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• 제16권1호
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• pp.54-58
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• 2007

실제 사진폐액에서 은의 회수를 위한 연속순환식 환원 공정을 적용하여 전해시간 및 두 전극간의 전압 차, 농도에 따른 영향을 검토하였다. 희석된 사진폐액에서의 은의 전해효율은 적용전압이 증가하면서 효율이 증가하다가 6V 정도에서 최고의 효율을 보였다. 그러나 그 이상 전압이 증가할수록 은의 회수율은 낮아지는 경향을 보였다. 희석되지 않은 원 사진폐액의 경우에서는 실험조건 하, 전해반응 시 적용 전압이 낮아질수록 효율을 높일 수 있음을 확인하였다.

• 한국자원식물학회지
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• 제30권6호
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• pp.670-678
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• 2017

Persimmon seeds contain considerable amounts of minerals, amino and organic acids, natural antioxidants and phenolic compounds. The objective of this study was to investigate quality characteristics and antioxidant potential of Korean persimmon seeds. The pH (4.88-4.94), color values, contents of minerals, free amino acids, organic acids, and phenolic compounds and DPPH free radical scavenging potentials of persimmon seed extracts significantly (p < 0.05) varied with the genotypes. This study showed that the seeds could be used as a source of different mineral elements (47.14-85.07 mg/kg) without any measureable amount of heavy metals such as arsenic, cadmium, lead and mercury. Similarly, considerable amounts of organic (1550.13-2413.08 mg/kg) and essential amino (50.85-54.03 mg/kg) acids and total phenolic compounds ($1227.91-1307.78{\mu}g$ gallic acid equivalent/g) were also found in the seed extracts, indicating their potential food value as a natural antioxidant. Results of the present study imply that prethanol-A, a food preservative, can be used as an effective extraction to obtain the minerals, organic and free amino acids, and phenolic compounds from the persimmon seeds, which possess a big potential to be commercially used in food, cosmetic and pharmaceutical industries.