• 제목/요약/키워드: Appearance Probability

검색결과 66건 처리시간 0.031초

A Domain Combination Based Probabilistic Framework for Protein-Protein Interaction Prediction (도메인 조합 기반 단백질-단백질 상호작용 확률 예측기법)

  • Han, Dong-Soo;Seo, Jung-Min;Kim, Hong-Soog;Jang, Woo-Hyuk
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 한국생물정보시스템생물학회 2003년도 제2차 연례학술대회 발표논문집
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    • pp.7-16
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    • 2003
  • In this paper, we propose a probabilistic framework to predict the interaction probability of proteins. The notion of domain combination and domain combination pair is newly introduced and the prediction model in the framework takes domain combination pair as a basic unit of protein interactions to overcome the limitations of the conventional domain pair based prediction systems. The framework largely consists of prediction preparation and service stages. In the prediction preparation stage, two appearance pro-bability matrices, which hold information on appearance frequencies of domain combination pairs in the interacting and non-interacting sets of protein pairs, are constructed. Based on the appearance probability matrix, a probability equation is devised. The equation maps a protein pair to a real number in the range of 0 to 1. Two distributions of interacting and non-interacting set of protein pairs are obtained using the equation. In the prediction service stage, the interaction probability of a protein pair is predicted using the distributions and the equation. The validity of the prediction model is evaluated fur the interacting set of protein pairs in Yeast organism and artificially generated non-interacting set of protein pairs. When 80% of the set of interacting protein pairs in DIP database are used as foaming set of interacting protein pairs, very high sensitivity(86%) and specificity(56%) are achieved within our framework.

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A Domain Combination-based Probabilistic Framework for Protein-Protein Interaction Prediction (도메인 조합 기반 단백질-단백질 상호작용 확률 예측 틀)

  • 한동수;서정민;김홍숙;장우혁
    • Journal of KIISE:Computing Practices and Letters
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    • 제10권4호
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    • pp.299-308
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    • 2004
  • In this paper, we propose a probabilistic framework to predict the interaction probability of proteins. The notion of domain combination and domain combination pair is newly introduced and the prediction model in the framework takes domain combination pair as a basic unit of protein interactions to overcome the limitations of the conventional domain pair based prediction systems. The framework largely consists of prediction preparation and service stages. In the prediction preparation stage, two appearance probability matrices, which hold information on appearance frequencies of domain combination pairs in the interacting and non-interacting sets of protein pairs, are constructed. Based on the appearance probability matrix, a probability equation is devised. The equation maps a protein pair to a real number in the range of 0 to 1. Two distributions of interacting and non-interacting set of protein pairs are obtained using the equation. In the prediction service stage, the interaction probability of a Protein pair is predicted using the distributions and the equation. The validity of the prediction model is evaluated for the interacting set of protein pairs in Yeast organism and artificially generated non-interacting set of protein pairs. When 80% of the set of interacting protein pairs in DIP database are used as teaming set of interacting protein pairs, very high sensitivity(86%) and specificity(56%) are achieved within our framework.

Multi-hop Routing Protocol based on Neighbor Conditions in Multichannel Ad-hoc Cognitive Radio Networks (인지 무선 애드혹 네트워크에서의 주변 상황을 고려한 협력적 멀티홉 라우팅 방법)

  • Park, Goon-Woo;Choi, Jae-Kark;Yoo, Sang-Jo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • 제36권4A호
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    • pp.369-379
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    • 2011
  • During the routing process between nodes on the CR(Cognitive Radio) network conducting for efficient use of limited frequency resources, spectrum handover process due to the appearance of the PU occupies most of the routing latency, and also decreases the reliability of the path. In this paper, a cooperative routing protocol in a multi-channel environment is proposed. The source node broadcasts a message with available channel lists and probability of PU appearance during its route guidance. The intermediate nodes re-transmit the message, received from the source node, and update and maintain the information, status table of the path. The destination node determines the optimal path and sends a reply message to the selected path after it receives the messages from the intermediate nodes. The average probability of the PU appearance and the average time of the PU appearance are updated while transferring data. During data transmission the channel with the lowest probability of appearance of the PU is selected dynamically and if a PU appears on the current channel partial repairment is performed. It is examined that reliability of the selected path considerably is improved and the routing cost is reduced significantly compared to traditional routing methods.

Comparison of Two Methods for Estimating the Appearance Probability of Seawater Temperature Difference for the Development of Ocean Thermal Energy (해양온도차에너지 개발을 위한 해수온도차 출현확률 산정 방법 비교)

  • Yoon, Dong-Young;Choi, Hyun-Woo;Lee, Kwang-Soo;Park, Jin-Soon;Kim, Kye-Hyun
    • Journal of the Korean Association of Geographic Information Studies
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    • 제13권2호
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    • pp.94-106
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    • 2010
  • Understanding of the amount of energy resources and site selection are required prior to develop Ocean Thermal Energy (OTE). It is necessary to calculate the appearance probability of difference of seawater temperature(${\Delta}T$) between sea surface layer and underwater layers. This research mainly aimed to calculate the appearance probability of ${\Delta}T$ using frequency analysis(FA) and harmonic analysis(HA), and compare the advantages and weaknesses of those methods which has used in the South Sea of Korea. Spatial scale for comparison of two methods was divided into local and global scales related to the estimation of energy resources amount and site selection. In global scale, the Probability Differences(PD) of calculated ${\Delta}T$ from using both methods were created as spatial distribution maps, and compared areas of PD. In local scale, both methods were compared with not only the results of PD at the region of highest probability but also bimonthly probabilities in the regions of highest and lowest PD. Basically, the strong relationship(pearson r=0.96, ${\alpha}$=0.05) between probabilities of two methods showed the usefulness of both methods. In global scale, the area of PD more than 10% was less than 5% of the whole area, which means both methods can be applied to estimate the amount of OTE resources. However, in practice, HA method was considered as a more pragmatic method due to its capability of calculating under various ${\Delta}T$ conditions. In local scale, there was no significant difference between the high probability areas by both methods, showing difference under 5%. However, while FA could detect the whole range of probability, HA had a disadvantage of inability of detecting probability less than 10%. Therefore it was analyzed that the HA is more suitable to estimate the amount of energy resources, and FA is more suitable to select the site for OTE development.

Classification based Knee Bone Detection using Context Information (문맥 정보를 이용한 분류 기반 무릎 뼈 검출 기법)

  • Shin, Seungyeon;Park, Sanghyun;Yun, Il Dong;Lee, Sang Uk
    • Journal of Broadcast Engineering
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    • 제18권3호
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    • pp.401-408
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    • 2013
  • In this paper, we propose a method that automatically detects organs having similar appearances in medical images by learning both context and appearance features. Since only the appearance feature is used to learn the classifier in most existing detection methods, detection errors occur when the medical images include multiple organs having similar appearances. In the proposed method, based on the probabilities acquired by the appearance-based classifier, new classifier containing the context feature is created by iteratively learning the characteristics of probability distribution around the interest voxel. Furthermore, both the efficiency and the accuracy are improved through 'region based voting scheme' in test stage. To evaluate the performance of the proposed method, we detect femur and tibia which have similar appearance from SKI10 knee joint dataset. The proposed method outperformed the detection method only using appearance feature in aspect of overall detection performance.

The Evaluation of Explosion For Toluene Storage Tank by Computer-Aided Fault Tree Analysis (Fault Tree Analysis(FTA)에 의한 Toluene저장 Tank의 폭발해석)

  • Chung, Jae-Hee;Yi, Young-Seop
    • Journal of the Korean Society of Safety
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    • 제3권2호
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    • pp.5-16
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    • 1988
  • This study is conducted to evaluate the explosion of tolune storage tank in the petrochemical plant by Fault Tree Analysis. The conclusions are as follows; 1) Fault Tree diagram and the required computer program for evaluation of explosion accident is developed. 2) The probability of the top event, explosion accident, is $1.5\;{\times}\;10^{-8}$ per year, so there is almost no possibility of explosion during the life cycle of tank. However, the probability of Gate 6 and Gate 7 is 8.8 per month, therefore, attention should be paid to them for accident prevention. 3) The number of minimal cut sets is 67 sets which are not calculated the probability of each set, because of the lack of computer capacity. All the minimal cut sets should be examined case by case. However, it is necessary to be paid attention to COM1, 126, 131, and COM4 in minimal cut sets, because the number of appearance is so high. 4) The number path sets is 70 sets which are not calculated the probability of each set, because of the lack of computer capacity. It is very useful to prepare safety checklist by using this minimal path sets. Also, the events which appear many times, 123, COM5, 139, 127 and 128, are very high in reliability.

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Contrast Enhancement using Dynamic Range Separate Histogram Equalization (동적영역 분할을 이용한 명암비 향상기법)

  • Kang, Hyun-Woo;Park, Gyu-Hee;Hwang, Bo-Hyun;Yun, Jong-Ho;Choi, Myung-Ryul
    • Proceedings of the IEEK Conference
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    • 대한전자공학회 2008년도 하계종합학술대회
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    • pp.917-918
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    • 2008
  • Histogram Equalization (HE) method is widely used for contrast enhancement. However, HE often introduce washed out appearance or color distortion due to the over enhancement in contrast. In this paper, Dynamic Range Separate Histogram Equalization (DRSHE) is proposed for contrast enhancement. DRSHE reconfigures the dynamic range of histogram using probability distribution ratio. The experimental results show that DRSHE suppresses the washed out appearance or color distortion and preserves naturalness of the original image compared with conventional methods.

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Development of Risk Evaluation Models for Railway Casualty Accidents (철도사상 사고위험도 평가 모델 개발에 관한 연구)

  • Park, Chan-Woo;Kim, Min-Su;Wang, Jong-Bae;Choi, Don-Bum
    • Proceedings of the KSR Conference
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    • 한국철도학회 2008년도 춘계학술대회 논문집
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    • pp.1499-1504
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    • 2008
  • This study shows risk-based evaluation results of casualty accidents for passengers, railway staffs and MOP(Member of public) on the national railway in South Korea. To evaluate risk of these accidents, the hazardous events and the hazardous factors were identified by the review of the accident history and engineering interpretation of the accident behavior. A probability evaluation model for each hazardous event which was based on the accident appearance scenario was developed by using the Fault Tree Analysis (FTA) technique. The probability for each hazardous event was evaluated from the historical data and structured expert judgment. In addition, the severity assessment model utilized by the Event Tree Analysis (ETA) technique was composed of the accident progress scenarios. And the severity for the hazardous events was estimated using fatalities and weighted injuries. The risk assessment model developed can be effectively utilized in defining the risk reduction measures in connection with the option analysis.

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A Study on Fault Diagnostic Model for Behaviour Appearance of Components (부품의 가동형태에 따른 고장진단 모델 연구)

  • 박주식;하정호;강경식
    • Journal of the Korea Safety Management & Science
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    • 제4권4호
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    • pp.97-108
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    • 2002
  • This study deals with the application of knowledge-based engineering and a methodology for the assessment & measurement of reliability, availability, maintainability, and safety of industrial systems using fault-tree representation. A fuzzy methodology for fault-tree evaluation seems to be an alternative solution to overcome the drawbacks of the conventional approach. To improve the quality of results, the membership functions must be approximated based on heuristic considerations. Conventionally, it is not always easy to obtain a system reliability for components with different individual failure probability density functions(p.d.f.), We utilize fuzzy set theory to solve the adequacy of the conventional probability in accounting and processing of built-in uncertainties in the probabilistic data. The purpose of this study is to propose the framework of knowledge-based engineering through integrating the various sources of knowledge involved in a FTA.

How do Export Pioneers Emerge and How are They Related to Product Creators?

  • HAHN, CHIN HEE
    • KDI Journal of Economic Policy
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    • 제43권1호
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    • pp.1-27
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    • 2021
  • In this paper, we empirically examine how export pioneers emerge and how they are related to product creators/innovators, utilizing a rich plant-product level dataset from the Korean manufacturing sector for the period of 1990-1998. Our analysis covers the process from the appearance of product creators as well as product imitators to the emergence of export pioneers. We find, first, that product imitators are larger, more productive and older than product creators. Second, most export pioneers are nevertheless found to be product creators. This result is largely due to the fact that almost all export pioneers export the products in the same year as product creation. Third, there are similarities as well as differences between product creators and export pioneers. Plants that are more productive or larger are more likely to become product creators as well as export pioneers. However, previous exporting experience positively affects the probability of export pioneering only, while plants' engagement in R&D positively affects the probability of product creation only. We discuss possible explanations for our main empirical results as well as their policy implications.