• Title/Summary/Keyword: AoA

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Evaluation of International Quality Control Procedures for Detecting Outliers in Water Temperature Time-series at Ieodo Ocean Research Station (이어도 해양과학기지 수온 시계열 자료의 이상값 검출을 위한 국제 품질검사의 성능 평가)

  • Min, Yongchim;Jun, Hyunjung;Jeong, Jin-Yong;Park, Sung-Hwan;Lee, Jaeik;Jeong, Jeongmin;Min, Inki;Kim, Yong Sun
    • Ocean and Polar Research
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    • v.43 no.4
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    • pp.229-243
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    • 2021
  • Quality control (QC) to process observed time series has become more critical as the types and amount of observed data have increased along with the development of ocean observing sensors and communication technology. International ocean observing institutions have developed and operated automatic QC procedures for these observed time series. In this study, the performance of automated QC procedures proposed by U.S. IOOS (Integrated Ocean Observing System), NDBC (National Data Buy Center), and OOI (Ocean Observatory Initiative) were evaluated for observed time-series particularly from the Yellow and East China Seas by taking advantage of a confusion matrix. We focused on detecting additive outliers (AO) and temporary change outliers (TCO) based on ocean temperature observation from the Ieodo Ocean Research Station (I-ORS) in 2013. Our results present that the IOOS variability check procedure tends to classify normal data as AO or TCO. The NDBC variability check tracks outliers well but also tends to classify a lot of normal data as abnormal, particularly in the case of rapidly fluctuating time-series. The OOI procedure seems to detect the AO and TCO most effectively and the rate of classifying normal data as abnormal is also the lowest among the international checks. However, all three checks need additional scrutiny because they often fail to classify outliers when intermittent observations are performed or as a result of systematic errors, as well as tending to classify normal data as outliers in the case where there is abrupt change in the observed data due to a sensor being located within a sharp boundary between two water masses, which is a common feature in shallow water observations. Therefore, this study underlines the necessity of developing a new QC algorithm for time-series occurring in a shallow sea.

Anti-Lipogenic Effect of Functional Cereal Samples on High Sucrose Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice (고당식이로 유도된 비알코올성 지방간 마우스에서 기능성 잡곡의 지질 대사 개선 효과)

  • Lee, Ko-Eun;Song, Jia-Le;Jeong, Byung-Jin;Jeong, Jong-Sung;Huh, Tae-Gon;Park, Kun-Young
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.6
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    • pp.789-796
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    • 2016
  • The anti-lipogenic effect of cereal samples on high sucrose diet (HSD)-induced non-alcoholic fatty liver disease (NAFLD) in mice was studied. We divided C57BL/6 mice into various groups based on 8 weeks of treatment with three types of cereal samples (HSD+WR, HSD diet containing 40% white rice; HSD+MCG, HSD diet containing 40% mixed cereal grain; HSD+AO-MCG, HSD diet containing 40% mixed antiobesity-cereal grain). After the experimental period, body weight changes, liver weights, serum lipid profiles, and hepatic fatty acid metabolism-related gene expression levels were determined. We found that HSD+WR, HSD+MCG, and HSD+AO-MCG treatments reduced body weight and liver weight, especially HSD+MCG and HSD+AO-MCG effectively reduced levels of serum triglycerides, total cholesterol, and low-density lipoprotein cholesterol. However, high density lipoprotein cholesterol levels increased compared to the control group. Furthermore, expression of hepatic lipogenic genes such as sterol regulatory element-binding protein-1c, acetyl-coenzyme A carboxylase, fatty acid synthase, stearoyl-coenzyme A desaturase-1, cluster of differentiation, and $PPAR-{\gamma}$ (peroxisome proliferator activated receptor ${\gamma}$) decreased, whereas expression of ${\beta}-oxidation$ genes such as $PPAR-{\alpha}$ and carnitine palmitoyl transferase-1 increased following HSD+MCG and HSD+AO-MCG treatment compared with levels in HSD+WR and control groups. These results suggest that the functional cereal samples, especially HSD+AO-MCG treatment, improved hepatic steatosis triggered by an HSD-induced imbalance in hepatic lipid metabolism.

Cl--Channel Is Essential for LDL-induced Cell Proliferation via the Activation of Erk1/2 and PI3K/Akt and the Upregulation of Egr-1 in Human Aortic Smooth Muscle Cells

  • Heo, Kyung-Sun;Ryoo, Sung-Woo;Kim, Lila;Nam, Miyoung;Baek, Seung-Tae;Lee, Hyemi;Lee, Ah-Reum;Park, Song-Kyu;Park, Youngwoo;Myung, Chang-Seon;Kim, Dong-Uk;Hoe, Kwang-Lae
    • Molecules and Cells
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    • v.26 no.5
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    • pp.468-473
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    • 2008
  • Low-density lipoprotein (LDL) induces cell proliferation in human aortic smooth muscle cells (hAoSMCs), which may be involved in atherogenesis and intimal hyperplasia. Recent studies have demonstrated that $Cl^-$ channels are related to vessel cell proliferation induced by a variety of stimuli. In this study, we investigated a potential role of $Cl^-$ channels in the signaling pathway of LDL effects on hAoSMC proliferation with a focus on the activation of Erk1/2-PI3K/Akt and the subsequent upregulation of Egr-1. $Cl^-$ channel blockers, DIDS, but neither NPPB nor Furosemide, completely abolished the LDL-induced DNA synthesis and cell proliferation. Moreover, DIDS, but not NPPB, significantly decreased LDL-stimulated $Cl^-$ concentration, as judged by flow cytometry analysis using MQAE as a $Cl^-$-detection dye. DIDS pretreatment completely abolished the activation of Erk1/2 and PI3K/Akt in a dose-dependent manner that is the hallmark of LDL activation, as judged by Western blot and proliferation assays. Moreover, pretreatment with DIDS ($Cl^-$ channel blockers) but not LY294002 (PI3K inhibitors) completely abolished the LDL-induced upregulation of Egr-1 to the same extent as PD98059 (MEK inhibitors to inhibit Erk), as judged by Western blot and luciferase reporter assays. This is the first report, to our knowledge, that DIDS-sensitive $Cl^-$-channels play a key role in the LDL-induced cell proliferation of hAoSMCs via the activation of Erk1/2 and PI3K/Akt and the upregulation of Egr-1.

Ch'ing Dragon Robes (청조의 용포소고)

  • 박춘순;김재임
    • Journal of the Korean Society of Costume
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    • v.50 no.3
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    • pp.59-72
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    • 2000
  • Dragon robe was defined as a robe on which the principal design consisted of dragon. Dragon patterns have been used on princess robes during T'and Dynasty. In Sung, Dragon-figured robes seem to have an Imperial prerogative. Yuan took over the use of robes with dragons patterns as a definite institition. Ming tried to reject all Yuan innovations, the dragon robe was retained as an unofficial court costume. The Emperor's semiformal robes which at first had four dragon medallions, later had twelve along with the 12 Symbols(십이장문). As Ch'ing dragon robes were only intended fro semiformal use. The Later Ch'ing robes date from after 1719, when the Ch'ien-lung(건륭) introduced 12 Symbols on Ch'ing robes. The Ch'ien-lung laws were disobeyed, notably the ones that specified the number of claws on the dragons. THe Emperor's dragon robe, lung-p'ao, (용포) was described as bright yellow in color, having four slits and horsefoof cuffs. The basic pattern consisted of nin dragons, in addition it had 12 Symbols. The elaborate textile techniques reached their peak in Ch'ing Dynasty-with its Weaving and Dyeing Office in Peking, and this factories at Hangchow(항주), Soochow(소주), and Naking(남경) -helps to explain why the decay of the Ch'ing bureaucracy hastended the decline of dragon robes. In the Ch'ing Dynasty tow terms were used for dragon robe, depending on the number of claws on the dragons. Those with five-clawed dragons were called lung-p'ao, while those with four-clawed dragons were called mang-p'ao(망포). The Court felt compelled to take corrective meausres. It decreeed that Ninisters of State and other officials, who had been bestowed five-clawed lung dragons, must take out one claw. Finally, the sale of ranks and the attendant privilege of wearing dragon robes gradually increased during the 18 th century, reaching its height in the 19 th century, Finally, after the Taiping Rebellion, when the Imperial Treasury was depleted by the wholesale destruction of revenue-producing lands, the Chinese government came to depend on such sales as an important source of revenue and the practice became even more widespread. The ensuing mass production of dragon robes, and the necessity of conforming to the fairly rigid basic pattern established in 1759, resulted in marked deterioration of workmanship, and a comparative monotony of decoration. The patterns on the dragon robes slight changes continued to be made in the ways of representign them. The li shui (입수) portion at the base of the robe become inreasingly wider throughout the 19th century. The background became cluttered with symbols of good fortune, scattered among the clouds and waves. As a result of all this extraneous decoration, the dragons were so crowded that they had to shrink back into the small size that they had originally occupied in the medallons. Kuang-hsu(광저) was a long one, allowing time for the manufacture of numerous robes. Also, it would seem likely that Occidental museums and collections would have a considerable number of his robes, in view of the widespread looting of his palaces during the Allied occupation of Peking in 1900, and the frequent sales of Late Ch'ing imperial textiles by destitute Manchu courtiers in the '20's.

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Effect of Dietary Supplementation of DHA and AA on the Incorporation of Long Chain Fatty Acid and DNA Content in the Developing Brain of Rats (쥐에서 뇌발달 과정중에 식이에 첨가한 DHA와 AA가 뇌조직의 지방산조성과 DNA 함량에 미치는 영향)

  • 박현서
    • Journal of Nutrition and Health
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    • v.32 no.5
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    • pp.526-532
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    • 1999
  • The aim of this study was to observe whether the dietary supplementation of docosahexaenoic acid(DHA). In growing rats requires extra supplementation of arachidonic acid(AA) for brain development. Sprague-Dawley rats were divided into three groups, each fed a different diet. In the FO group, dams were fed a DHA-rich FO diet during pregnancy and lactation and pups were fed the same diet until 10 weeks old. In the AO group dams and pups were similarly fed a FO diet after weaning. DHA and AA were most effetively deposited in the developing brain during pregnancy and lactation in rats. However, FO-W pups showed significantly lower level of DHA at 0-3 weeks compared with the FO and AO groups and than slowly increased DHA levels to about 87% of other groups at 10 weeks with the introduction of the FO diet after weaning. The total amount of DNA in whole brain rapidly reached a maximum level at 3 weeks and then was sustained at a constant level after 5 weeks of age. The DNA content was positively correlated with DHA level but not with AA level in the developing brain. DNA content was significantly lower in the FO-W group compared to the FO and AO group at 3 weeks of age. However, the DNA content of brain in FO-W pups increased to 80% of the FO group level at 10 weeks after feeding the FO diet after weaning. The relative percentage of AA in brain lipids was significantly reduced in the early stage of brain development when only DHA was supplemented. However, DHA supplementation had no significant effect on the incorporation of AA when the approximately 35% of LA in the FO diet was substituted by preformed AA. These results suggest that large quantities of DHA could interfere with the normal conversion of LA to AA if LA is not supplemented enough together with DHA. Therefore, high DHA supplementation may require preformed AA in the diet even though AA has no significant correlation with the DNA content in brain. DHA supplementation after weaning also improved the incorporation of DHA into brain and content of DNA even though brain development was almost completed, suggesting that a low level of DHA supplementation without AA addition might be necessary to improve brain development during infancy as well as during pregnancy and lactation.

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Potential of Contaminant Removal Using a Full-Scale Municipal Water Treatment System with Adsorption as Post-Treatment (실 규모 물 처리 공정 및 후속 흡착 처리에 의한 오염원 제거 잠재성 평가)

  • Haeil Byeon;Geonhee Yeo;Anh-Hong Nguyen;Youngwoong Kim;Donggun Kim;Taehun Lee;Seolhwa Jeong;Younghoa Choi;Seungdae Oh
    • Land and Housing Review
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    • v.15 no.1
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    • pp.167-177
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    • 2024
  • This study aimed to assess the efficacy of an adsorption process in removing organic matter and micropollutant residuals. After a full-scale water circulation system, the adsorption process was considered a post-treatment step. The system, treating anthropogenically impacted surface waters, comprises a hydro-cyclone, coagulation, flocculation, and dissolved air flotation unit. While the system generally maintained stable and satisfactory effluent quality standards over months, it did not meet the highest standard for organic matter (as determined by chemical oxygen demands). Adsorption experiments utilized two granular activated carbon types, GAC 830 and GCN 830, derived from coal and coconut-shell feedstocks, respectively. The assessment encompassed organic materials along with two notable micropollutants: acetaminophen (APAP) and acid orange 7 (AO7). Adsorption kinetics and isotherm experiments were conducted to determine adsorption rates and maximum adsorption amounts. The quantitative findings derived from pseudo-second-order kinetics and Langmuir isotherm models suggest the effectiveness of the adsorption process. The findings of this study propose the potential of employing the adsorption process as a post-treatment to enhance the treatment of contaminants that are not satisfactorily treated by conventional water circulation systems. This enhancement is crucial for ensuring the sustainability of urban water cycles.

A Study on New Song of the Sky Pacers (신법보천가(新法步天歌) 연구)

  • Ahn, Sang-Hyeon
    • Journal of Astronomy and Space Sciences
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    • v.26 no.4
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    • pp.589-602
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    • 2009
  • We investigated 'Song of the Sky Pacers, Adopted to the New Methods'(新法步天歌), the latest version of Joseon's 'Song of the Sky Pacers'(步天歌). Due to the influence of new knowledge on Chinese asterisms imported from the Ching dynasty, 'Song of the Sky Pacers with New Star-Charts' was written in the eighteenth century. However, the disagreement between song and star-charts was causing confusion in practical applications such as Joseon's national examination for selecting astronomers. In order to improve this situation, Royal Observatory of the Joseon dynasty (觀象監) published 'Song of the Sky Pacers, Adopted to the New Methods' based upon star-charts and song in the Sequel of I-Hsiang-K'ao-ch'eng (欽定儀象考成續編). The New Song was edited by a middle-class professional astronomer Yi Jun-yang (李俊養), and corrected by a nobleman Nam Byeong-gil (南秉吉). We establish a brief biography of Yi Jun-yang. The New Song preserves the genuine characteristics of previous Joseon's Song including the format of title of each lunar mansion and description on the location of the Milky Way in the asterisms. The description of the Milky Way was newly written based on the data in volume 31 and 32 of the Sequel of I-Hsiang-K'ao-ch'eng.

Taxonomy of Yellow koji mold (Aspergillus flavus/oryzae) in Korea

  • Hong, Seung-Beom;Lee, Mina;Kim, Dae-Ho;Chung, Soo-Hyun;Samson, Robert A.
    • 한국균학회소식:학술대회논문집
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    • 2014.05a
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    • pp.25-25
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    • 2014
  • Koji molds are comprised of yellow, black and white. Black and white koji molds were recently re-visited by this author and it is concluded that they consists of Aspergillus luchuesnsis, A. niger and A. tubingensis, and the most important species for alcoholic beverage production is A. luchuensis. In the case of yellow koji mold, it is comprised of Aspergillus oryzae, A. sojae and A. tamari. In the case of A. sojae, the species is scarcely isolated from nature and rarely used for industry in Korea. Aspergillus tamari is often isolated from traditional Korean Meju, a fermented soybean product, and the classification of the species is clear. However, in the case of A. oryzae, differentiation between A. oryzae and A. flavus is still in controversy. In this study, we collected 415 strains of Aspergillus flavus/oryzae complex from air, rice straw, soybean, corn, peanut, arable soil and Meju in Korea and we examined the aflatoxin producing capacity of the strains. The norB-cypA, omtA and aflR genes in the aflatoxin biosynthesis gene cluster were analyzed. We found that 367 strains (88.4%) belonged to non-aflatoxigenic group (Type I of norB-cypA, IB-L-B-, IC-AO, or IA-L-B- of omtA, and AO type of aflR), and only 48 strains (11.6%) belonged to aflatoxin-producible group (Type II of norB-cypA, IC-L-B+/B- or IC-L-B+ of omtA, and AF type of aflR). In the case of A. flavus/oryzae strains from Meju, almost strains (178/192, 92.7%) belonged to non-aflatoxigenic group and only 14 strains (7.3 %) belonged to aflatoxin-producible group. It is proposed in this study that non-aflatoxigenic strain from Meju is classified as A. oryzae, considering that Meju is food material.

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Alkyl and Alkenyl Substituent Effects on Nonbonded Interactions of Hexatriene

  • Lee, Ik-Choon;Rhyu, Keun-Bae;Lee, Bon-Su
    • Bulletin of the Korean Chemical Society
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    • v.2 no.1
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    • pp.12-16
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    • 1981
  • Alkyl and alkenyl substituent effects on nonbonded interactions of hexatriene were examined using CNDO/2 method. The results showed that: (1) rapid rate of thermal electrocyclization of 3-vinyl hexa-1, 3, 5-triene is due to increased overlap population between atom pair reacting resulting from strong electron repelling interaction of vinly group on the triene moiety; (2) stability of a conformer is determined by additive effect of composite ${\pi}$ structures; (3) a substituent on positions 2 and 3 increases the HOMO AO coefficient of sites 1 and 4 considerably and activates interactions with these sites.

A Phonetic Study og German (2) (독어음의 음성학적 고찰(2) - 현대독어의 복모음에 관하여 -)

  • Yun Jong-sun
    • MALSORI
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    • no.19_20
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    • pp.33-42
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    • 1990
  • Those who are interested in the German diphthongs wil1 find that they are classified into three kinds of forms in accordance with their gliding directions: closing, centring and rising. The German [aI], for example, which derives its origin from [i:] of the riddle high German. Is regarded as a distinctive feature that distinguishes the new high German from the middle high German. The diphthong [aI] is cal led fall ing one, because the sonority of the sound undergoes a diminution as the articulation proceeds. The end part of the diphthong [aI] is less sonorous than the beginning part. In most of the German diphthongs the diminution of prominence is caused by the fact that the end part is inherently less sonorous than the beginning. This applies to the other c los Ing and centring diphthongs. This way of diminution of sonority exerts influence on methods of constructing systems of phonetic notation. The above mentioned less sonorous end part of diphthong [I] shows that it differs from some analogous sound in another context. It is useful to demonstrate the occurrence of particular allophones by introducing special symbols to denote them (here: at→ae). Forms of transcription embodying extra symbol s are cal led narrow. But since strict adherence to the principle 'one sound one symbol' would involve the introduction of a large number of symbols, this would render phonetic transcriptions cumbrous and difficult to read. A broad style of transcription provides 'one symbol for each phoneme' of the language that is transcribed. Phonemic transcriptions are simple and unambiguous to everyone who knows the principles governing the use of allophones in the language transcribed. Among those German ways of transcriptions of diphthongs ( a?, a?, ??: ae, ao, ?ø; ae, ao, ?ø) the phonemic (broad) transcription is general Iy to be recommended, for Instance, in teaching the pronunciation of a foreign language, since it combines accuracy with the greatest measure of simplicity (Some passages and terms from Daniel Jones) .

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