• 한국한의학연구원논문집
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• 제3권1호
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• pp.67-83
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• 1997

In order to search for anti-influenza virus type A agents from Korean medicinal herbs, we selected 100 medicinal herbs, based on a review of the Korean traditional medicine books. Four of 100 Korean medicinal herbs, MM-40, MM-55, MM-63, MM-110, exhibited very strong anti-influenza virus activity. The fractions of four medicinal herbs, which had very strong anti-influenza virus activity, were tested for antiviral activity by means of Haemagglutination inhibition test(HTT), 40% MeOH fraction of MM-40, $H_2O$ fraction of MM-55, 20% fraction of MM-63 3nd $H_2O$ fraction of MM-110 had strong anti-influenza virus activity at the range of $78{\mu}g/ml$ to $156{\mu}g/ml$, 1.56mg/ml to 100mg/ml, 6.25mg/ml to 50mg/ml and $48.7{\mu}g/ml$ to $780{\mu}g/ml$, respectively. These results of HIT indicated that fractions of Korean medicinal herbs might inhibit either attachment of virus to cell surface receptor or penetration of virus into cell during the initial stage of infection. In the cytotoxicity of fractions against red blood cells, 40% MeOH fraction of MM-40, 20% fraction of MM-63 and $H_2O$ fraction of MM-110 showed cytotoxicity at the range of $78{\mu}g/ml$ to 10mg/ml, 50mg/ml to 100mg/ml and $195{\mu}g/ml$ to 100mg/ml, respectively, whereas $H_2O$ fraction of MM-55 did not show cytotoxicity. In order to establish influenza virus adapted animal model, influenza virus type A were passaged 3 and 4 times successively in Balb/c mouse. As a result, we had 4 HA unit titers on the 5 days of 3rd passages and 7 days of 4th passages after infection, respectively.

• 한국염색가공학회지
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• 제26권1호
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• pp.45-52
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• 2014

Red pine (Pinus densiflora) is widely used traditional medicine, pharmacological and nutritional values from which the phytochemical compounds are derived. The present study was aimed to examine the antibacterial effects in the absence and presence of a immature red pine cone extract against 13 microorganisms. The components in the aqueous extract from immature red pine cone were identified by GC-MS. About 1.4% of total polyphenolic compound was measured in aqueous extract collected from immature red pine cone. Also, the high concentration of ${\beta}$-phellenandrene, ${\alpha}$-pinene, limonene, bornyl acetate and aldehyde was detected in total ion chromatograms. Of total 13 microorganisms, 4 microorganisms including Pseudomonas aeruginosa, Vibrio cholera, Listeria monocytogenes, Klebsiella pneumonia were effectively killed by aqueous extract of immature red pine cone. The highest anti-bacterial effect was detected in P. aeruginosa, followed by V. cholera, L. monocytogenes and K. pneumonia. In case of P. aeruginosa, the largest diameter of inhibition zone was maintained to 1/2 solution treated cells and slightly decreased at 1/4 and 1/8 solution treated cells. Also, in test used V. cholera and L. monocytogenes, the inhibition zone was strongly formed in only 1 and 1/2 solution treated cells, while K. pneumonia showed the very small diameter of inhibition zone in all concentrations. Therefore, these results suggested that the aqueous extracts of immature red pine cone should be considered as a new and potentially important anti-bacterial substrate to effectively prevent the microbial infection and penetration.

• 한국건설순환자원학회논문집
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• 제4권3호
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• pp.243-249
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• 2016

본 연구에서는 시멘트계 보수재 코팅이 철판의 부식 저항성에 미치는 영향을 평가하가 위해 보통 철판(Normal), 용접철판(Welding), 용접 후 보수재 철판(Welding & coating)의 세 가지 경우에 대하여 7일간 ICM(Impressed Current Method)를 통하여 부식을 촉진시켰다. 이후 Faraday 법칙을 통해 얻은 이론 부식률, 실험 부식률 그리고 부식 실험 후 측정한 휨 강도를 비교 평가하였다. Normal case와 Welding case에서는 약 70% 수준의 부식률이 측정되었으며, Welding & coating case에서는 약 17%정도의 부식률이 측정되었다. 이는 시멘트계 보수재료의 코팅이 염화물 이온의 침투를 효과적으로 차단하였으며 이로 인해 부식전류의 발생이 억제되었기 때문이다. 휨 강도 역시 부식률 평가와 같은 경향을 나타내었으며 Welding & coating case에서 Welding case 대비 약 3.4배 큰 강도가 평가되었다. 시멘트계 보수재 코팅이 용접부에 시행되면 용접부 철판의 부식 차단에 효과적일 것으로 판단된다.

• 한국도로학회논문집
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• 제18권3호
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• pp.59-65
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• 2016

PURPOSES : This paper aims to develop a road pavement de-icing system using carbon sheet to replace the older snow de-icing method. Carbon sheet is a light and high-strength metal. Hence, various bodies of research for its applications in many industries have progressed. METHODS : The experiment was conducted in a laboratory. The carbon sheet supplied voltage through a power supply system, and produced heat transfers to the concrete surface. Various factors, such as pavement material, carbon sheet width, penetration depth, and freezing-thawing resistance, were considered in the conducted experiments to confirm the heating transfer efficiency of the carbon sheet. RESULTS : The carbon sheet used was a conductor. Therefore, it produced heat if voltage was supplied. The exposed carbon sheet on the atmosphere did not affect the carbon sheet width when it provided constant voltage. However, the sheet showed different heating behaviors by width change when the carbon sheet penetrated into the concrete. Moreover, the freezing-thawing resistance was decreased by the carbon sheet with increasing width. CONCLUSIONS : The experiments confirmed the possibility of developing a road snow melting system using a carbon sheet. The antiicing system using the carbon sheet to replace the traditional anti-icing system has disadvantages of environmental pollution risk and electric leakage. The pavement also improved its toughness resistance. The utilization value will be very high in the future if carbon sheet heat loss can be minimized and durability is improved.

• 한국윤활학회:학술대회논문집
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• 한국윤활학회 2003년도 학술대회지
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• pp.139-148
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• 2003

In this study, biodegradable base Li-greases were prepared by using Li-soap thickener and vegetable oils such as soybean oil, rapeseed oil, castor oil and synthetic ester. Also, EP-greases were formulated by blending base Li-greases, anti-wear additives, EP additives, anti-oxidants and corrosion inhibitor etc. And EP-greases were characterized by analysing physical properties such as worked penetration, dropping point, 4-ball wear, extreme pressure, thermal properties etc. Biodegradability of base Li-greases and EP-greases were evaluated by CEC-L-33-A-93 method using several inoculums of domestic sewage treatment plant. As the results, biodegradability of vegetable oils were shown at the range of 97.1 to $98.4\%$. And biodegradability of base Li-greases and EP-greases were $86.2\%\;\~\;89.3\%\;and\;83.4\%\;\~\;90.0\%$ which were lower value than those o( vegetable oils due to effect of Li-soap thickener, respectively. Therefore, the EP-greases prepared in this study were easily biodegraded by microorgnism.

• 한국재난정보학회 논문집
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• 제10권1호
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• pp.91-97
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• 2014

본 연구는 기존 설치된 주민대피시설의 실태조사를 통해 주민대피시설의 계획 및 설계에 필요한 기초자료로서의 활용을 목적으로 진행되었다. 그 결과, 첫째, 주민대피시설이 고폭탄 위주의 방호만을 고려하여 설계된 것으로 판단되나, 시설물의 출구방향, 주출입구 방호능력 등을 살펴보았을 때 실제 고폭탄에 대한 방호능력은 상당히 떨어지는 것으로 판단된다. 둘째, 전체 7개 시설은 외부에서 내부로 유입되는 공기에 대한 공기여과청정기가 설치되어 있지 않으며, 외부에 설치된 흡 배기구의 높이도 지상과 근접하게 위치하고 있어 공기보다 무거운 오염공기의 내부 유입을 발생 시킬 수 있다. 셋째, 일부시설은 방폭문이 설치되어 있으나 개구부, 방폭밸브의 역방향 등의 적절하지 못한 설치와 배관 배선의 관통부 마감상태로 인해 정상적인 방폭문의 기능유지 및 기밀성 확보는 어려울 것으로 판단된다.

• 대한족부족관절학회지
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• 제5권1호
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• pp.18-22
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• 2001

Most of Danis-Weber type B fracture has an oblique fracture plane proximal posteriorly to distal anteriorly. In these cases, the lateral plate has become widely accepted. However some limitation to the use of the lateral plate exist. The plate must be bent accurately and the screws in the distal fragment must be unicortical to avoid penetration into the joint, predisposing it to poor fixation in the osteoporotic bone. In 1982, Brunner and Weber introduced the antiglide plate for fixation of the shaft oblique fracture of the distal fibula, but it has not widely used. The author reviewed 21 cases treated by antiglide plate fixation from March, 1995 to March, 1999 which could be follow-up more than 1 year. We analysed the result radiographically and clinically using Ankle-Hindfoot scale(100 % total) of the American Orthopedic Foot and Ankle Society. The results obrained were as follows: 1. All fracture were united at average 8 weeks clinically and radiographically. 2. According to the Ankle- Hindfoot scale, 8 cases were above 90 points, 11 cases were beet ween 80 and 89 points and two cases were below 80 points. 3. One case had an injury to intermediate dorsal cutaneous nerve.

• Parasites, Hosts and Diseases
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• 제57권1호
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• pp.1-8
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• 2019

There is no effective treatment modality available against different forms of leishmaniasis. Therefore, the aim of this study was to improve the penetration and efficacy of selenium and glucantime coupled with niosomes and compared them with their simple forms alone on in vitro susceptibility assays. In this study, the niosomal formulations of selenium and in combination with glucantime were prepared. The size and morphology of the niosomal formulations were characterized and the effectivity of the new formulation was also evaluated using in vitro MTT assay, intra-macrophage model, and gene expression profile. From the results obtained, no cytotoxicity effect was observed for niosomal and simple forms of drugs, as alone or in combination. Niosomal formulations of the drugs significantly showed more inhibitory effects ($P{\leq}0.001$) than the simple drugs when the selectivity index was considered. The gene expression levels of Interleukin (IL-10) significantly decreased, while the level of IL-12 and metacaspase significantly increased ($P{\leq}0.001$). The results of the present study showed that selenium plus glucantime niosome possess a potent anti-leishmanial effect and enhanced their lethal activity as evidenced by the in vitro experiments.

• 대한토목학회논문집
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• 제39권4호
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• pp.523-530
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• 2019

포트홀 발생 및 관련 교통사고 건수는 매년 꾸준히 증가하는 추세이며 이에 따른 인명피해, 차량파손에 따른 비용손실 등 도로 이용자의 직 간접적인 피해를 증가시키고 있다. 일반적으로 아스팔트 혼합물은 생산과정부터 시공 후 공용에 따라 지속적으로 노화가 진행된다. 포장 노화는 균열과 수분침투로 박리를 야기하고 반복적인 윤하중에 의해 포장구조를 약화시켜 포트홀을 유발하게 된다. 본 연구에서는 노화가 아스팔트 콘크리트 포장에 미치는 영향을 검토하기 위해 노화정도에 따른 부착성능 평가와 수분민감성 평가를 수행하였다. 연구결과 노화에 따라 아스팔트 바인더의 점성이 증가해 부착강도가 2~3배 이상 증가하였다. 또한 가속 노화시킨 아스팔트 혼합물의 경우 간접인장강도의 증가뿐만 아니라 TSR 값도 4.2~8.9 % 증가하는 것으로 나타났다. 이에 따라 골재에 아스팔트 바인더가 피복된 상태에서 노화가 진행될 경우 아스팔트 바인더와 골재의 부착력이 증가하여 박리 저항성이 향상되는 것으로 분석되었다.

• Journal of the Korean Wood Science and Technology
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• 제32권2호
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• pp.50-57
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• 2004

본 실험은 건조되지 않은 목재를 고온의 아마인유에 침지처리함으로써 목재건조와 동시에 발수효과를 얻고자 실시하였다.함수율 90% 이상의 소나무생재를 온도 150℃의 아마인유에서 6시간 침지처리하였을 때 목재함수율은 10%까지 떨어졌으며, 목재 축방향의 깊이에 관계없이 목재단면의 20%에 해당하는 아마인유가 침투하였다. 이때 목재의 강도적 손실은 발생하지 않는 것으로 나타났다. 목재표면의 천공처리는 목재의 내부할열방지에 효과적이었고, 아마인유의 깊은 침투를 유도할 수 있었다. 흡수성 시험 결과 처리재는 무처리재에 비하여 높은 발수효과를 나타냈다. 변색균 및 부후균에 대한 항균효력시험은 처리재 자체로서 균에 대한 독성 기작이 없었으나, 백색부후균 및 갈색부후균에 대해서는 무처리재보다 낮은 중량감소율을 나타내는 등 방부효력의 상승이 있었다.