• Title/Summary/Keyword: Anatomical variants

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Endobronchial Carcinosarcoma (기관지내 암육종)

  • 조덕곤;곽문섭;김치홍;문성배;장은덕
    • Korean Journal of Bronchoesophagology
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    • v.3 no.1
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    • pp.122-127
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    • 1997
  • Carcinosarcoma of the lung is a rare turner with an admixture of malignant epithelial(carcinomatous) and malignant mesenchymal (sarcomatous) components. Clinicopathologically, pulmonary carcinosarcoma has been divided into two types by its anatomical locations and growth nature, peripheral parenchymal and central endobronchial variants. We experienced an endobronchial carcinosarcoma that induced complete atelectasis of the right lung due to polypoid growing mass from the right upper lobe bronchus in a 67 year old male smoker. The patient underwent a successful right pneumonectomy. The tumor was composed of squamous cell carcinoma with variable sarcomatous differentiation into myogenous and undifferenciated sarcoma that demonstrated by immunohistochemical study. The patient has been doing well for the last seven months since the operation, without metastases or turner recurrence.

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Bilateral sternocleidomastoid variant with six distinct insertions along the superior nuchal line

  • Dupont, Graham;Iwanaga, Joe;Altafulla, Juan J.;Lachkar, Stefan;Oskouian, Rod J.;Tubbs, R. Shane
    • Anatomy and Cell Biology
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    • v.51 no.4
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    • pp.305-308
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    • 2018
  • Anatomical variations of the sternocleidomastoid muscle (SCM) have been observed to occupy multiple origins and insertion points and have supernumerary heads, sometimes varying in thickness. During routine dissection, a SCM was observed to have six distinct insertions that interface with the course of the superior nuchal line, ending at the midline, bilaterally. This variation was also seen to receive innervation from the accessory nerve as well as the great auricular nerve. To our knowledge, this variant of supernumerary insertions and nerve innervations has not yet been reported. These variants may pose as problematic during surgical approaches to the upper neck and occiput, and should thus be appreciated by the clinician. Herein we discuss the case report, possible embryological origins, and the clinical significance of the observed variant SCM.

Bertolotti's Syndrome Misdiagnosed as Juvenile Idiopathic Arthritis in an Adolescent Girl with Low Back Pain (소아 특발성 관절염과 관련된 요통으로 오인된 베르톨로티 증후군)

  • Han, Seung Hee;Kim, JoongGon;KIM, JongKyu
    • Clinical Pain
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    • v.20 no.1
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    • pp.35-38
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    • 2021
  • Bertolotti's syndrome is a congenital abnormality in which the expanded lower lumbar transverse process articulates with the ilium or sacrum. It is an important cause of low back pain in children and adolescents that is frequently misdiagnosed. We describe the case of a 17-year-old girl with low back pain who had a 4-year history of juvenile idiopathic arthritis. She subsequently underwent plain radiography and magnetic resonance imaging and was eventually diagnosed with Bertolotti's syndrome. She was managed conservatively with 6 weeks of physical therapy and an exercise program, and her pain subsided. This case demonstrates the importance of considering anatomical and structural variants when evaluating low back pain in adolescents.

Superficial Radial Neuropathy due to Anatomic Variation: A Case Report (해부학적 변이로 인한 표재성 요골 신경병증: 증례 보고)

  • Changwon Choi;Hye Jung Choo
    • Journal of the Korean Society of Radiology
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    • v.85 no.2
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    • pp.468-473
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    • 2024
  • Superficial radial neuropathy is a purely sensory neuropathy, usually caused by nerve entrapment in the distal forearm. We report a case of superficial radial neuropathy caused by the anomalous course of the superficial radial nerve, which was found to be spirally encircling the brachioradialis tendon in the distal forearm. To the best of our knowledge, this is the first report of an anatomical variant of the superficial radial nerve that causes neuropathy.

The prevalence and distribution of the variants of Gantzer's muscle: a meta-analysis of cadaveric studies

  • Adil Asghar;Rakesh Kumar Jha;Apurba Patra;Binita Chaudhary;Brijendra Singh
    • Anatomy and Cell Biology
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    • v.55 no.1
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    • pp.3-13
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    • 2022
  • The Gantzer's muscle is often present in the flexor compartment of the forearm. It lies underneath flexor digitorum superficialis and compresses the anterior interosseous nerve. Furthermore, this muscle frequently bestows an accessory muscle of flexor pollicis longus or flexor digitorum profundus, or sometimes together. The current meta-analysis aims to compute the prevalence of subtypes of Gantzer's muscle. Major electronic databases (PubMed, Scopus, Google Scholar, etc.) were searched for title and abstract. After removing the duplicate citations, the titles/abstracts were shortlisted with the help of inclusion and exclusion criteria. The shortlisted titles/abstracts were downloaded or collected from the library. The data of all subtypes of Gantzer's muscle were pooled from shortlisted published manuscripts for meta-analysis. The pooled estimate of other anatomical characteristics was also observed. A total of 59 cadaveric studies of sample size 5,903 were evaluated for pooled prevalence of flexor pollicis longus (accessory head). Similarly, the authors evaluated 14 studies of 1,627 upper limbs for flexor digitorum profundus (accessory head). The unit of analysis was per 100 upper limbs. The Pooled prevalence of accessory muscle of flexor pollicis longus and flexor digitorum profundus were 48% (95% CI, 44%-52%) and 17% (95% CI, 13%-21%), respectively. The Gantzer's muscle is present in 2/3rd of the upper limbs. Accessory head of flexor pollicis longus is almost three times more common than the accessory head of flexor digitorum profundus. A classification of Gantzer's muscle is needed to reduce the ignorance of these variants.

Multiple roles of phosphoinositide-specific phospholipase C isozymes

  • Suh, Pann-Ghill;Park, Jae-Il;Manzoli, Lucia;Cocco, Lucio;Peak, Joanna C.;Katan, Matilda;Fukami, Kiyoko;Kataoka, Tohru;Yun, Sang-Uk;Ryu, Sung-Ho
    • BMB Reports
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    • v.41 no.6
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    • pp.415-434
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    • 2008
  • Phosphoinositide-specific phospholipase C is an effector molecule in the signal transduction process. It generates two second messengers, inositol-1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. Currently, thirteen mammal PLC isozymes have been identified, and they are divided into six groups: PLC-$\beta$, -$\gamma$, -$\delta$, -$\varepsilon$, -$\zeta$ and -$\eta$. Sequence analysis studies demonstrated that each isozyme has more than one alternative splicing variant. PLC isozymes contain the X and Y domains that are responsible for catalytic activity. Several other domains including the PH domain, the C2 domain and EF hand motifs are involved in various biological functions of PLC isozymes as signaling proteins. The distribution of PLC isozymes is tissue and organ specific. Recent studies on isolated cells and knockout mice depleted of PLC isozymes have revealed their distinct phenotypes. Given the specificity in distribution and cellular localization, it is clear that each PLC isozyme bears a unique function in the modulation of physiological responses. In this review, we discuss the structural organization, enzymatic properties and molecular diversity of PLC splicing variants and study functional and physiological roles of each isozyme.

Relationship between cotyledon Number and Vascular System in Carrot Seedling (당근 유식물체에서 자엽수와 유관속계의 관련성)

  • 김경식
    • Korean Journal of Plant Resources
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    • v.11 no.1
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    • pp.30-39
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    • 1998
  • Carrot seedling emgryos showing variations in cotyledon number were selected and anatomical comparisons of the embryo vascular systems were performed between the variants and normal two cotyledonary (5) embryos from 800 seedings germinated . Externally, all of the four and six cotyledonary embryos had two cotyledonary petioles. Each of the cotyledonary petioles divided into two or three on the upper part fo the petiole which result in four and six cotyledons, respectively. However, the embryos had three different cotyledonary petioles in the three cotyledonary embryos. On the basis of the pattern of vascular system, the four and six cotyledonary embryos had the same basic vascular system as fnormal two cotyledonary embryos, Therefore the cotyledon number abnormality could result from the branching split of the abnormally thickened upper part of the cotyledonary petiole. However, the three cotyledonaryembryos had a different vascular system from the normla two cotyledonary embryos. They could be regarded as different varieties form the two cotyledon embryos. All embryos observed had short cylindrical plumule sheath which formed by the fusion of the cotyledon bases. The presence of plumule sheath strontgly implied that the initiation of the cotyledons was not from the two localized primordia but from the circular proimordiu formed at the blobular stageof embryo, and it is not consistent with current views of cotyledon initiation. On the formation of the primary vascular system of carrot seedlings, it is suggested that the primary vascular system of the plumule was formed independently from that of the root-hypocotyle-cotyledon system.

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Computed tomographic anatomy of hepatic artery in normal beagle dogs

  • Kim, Soochan;Jeong, Seongmok;Lee, Heechun;Lee, Youngwon;Choi, Hojung
    • Korean Journal of Veterinary Research
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    • v.59 no.2
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    • pp.55-58
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    • 2019
  • This study was performed to examine the visualization and anatomical variants of the hepatic artery with dual-phase computed tomography (CT) angiography and three-dimensional volume rendering imaging analysis in clinically normal dogs. Seven healthy beagle dogs were enrolled and underwent dual CT angiography. Arterial phase images could be obtained with multi-detector CT angiography using the fixed-scan method in these dogs. Contrast enhancement of the hepatic parenchyma was quite minimal because of the unique blood supply system of the liver. In most dogs, the main hepatic arterial branches were the right lateral branch, left branch, and right medial branch. Although hepatic arterial variation appears to be common in dogs, only one dog in this study had the caudate lobar branch as the first branch of the hepatic artery. Further study on a larger number of dogs with CT images will be needed to identify and classify the pattern of hepatic arterial variations.

Patellofemoral Instability in Children: Imaging Findings and Therapeutic Approaches

  • Hee Kyung Kim;Shital Parikh
    • Korean Journal of Radiology
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    • v.23 no.6
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    • pp.674-687
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    • 2022
  • Patellofemoral instability (PFI) is common in pediatric knee injuries. PFI results from loss of balance in the dynamic relationship of the patella in the femoral trochlear groove. Patellar lateral dislocation, which is at the extreme of the PFI, results from medial stabilizer injury and leads to the patella hitting the lateral femoral condyle. Multiple contributing factors to PFI have been described, including anatomical variants and altered biomechanics. Femoral condyle dysplasia is a major risk factor for PFI. Medial stabilizer injury contributes to PFI by creating an imbalance in dynamic vectors of the patella. Increased Q angle, femoral anteversion, and lateral insertion of the patellar tendon are additional contributing factors that affect dynamic vectors on the patella. An imbalance in the dynamics results in patellofemoral malalignment, which can be recognized by the presence of patella alta, patellar lateral tilt, and lateral subluxation. Dynamic cross-sectional images are useful for in vivo tracking of the patella in patients with PFI. Therapeutic approaches aim to restore normal patellofemoral dynamics and prevent persistent PFI. In this article, the imaging findings of PFI, including risk factors and characteristic findings of acute lateral patellar dislocation, are reviewed. Non-surgical and surgical approaches to PFI in pediatric patients are discussed.

Assessment of the anterior loop of the inferior alveolar nerve via cone-beam computed tomography

  • Shaban, Baratollah;Khajavi, Amin;Khaki, Nasim;Mohiti, Yones;Mehri, Tahere;Kermani, Hamed
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.43 no.6
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    • pp.395-400
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    • 2017
  • Objectives: The aim of this study was to evaluate different anatomical variants of the anterior loop of the inferior alveolar nerve (IAN) via cone-beam computed tomography (CBCT). Materials and Methods: CBCT images of 71 patients (36 males and 35 females) were evaluated. We used the classification described by Solar for IAN evaluation. In this classification, three different types of IAN loops were introduced prior to emerging from the mental foramen. We classified patients according to this system and introduced a new, fourth type. Results: Type I was seen in 15 sites (10.6%), type II in 39 sites (27.5%), and type III in 50 sites (35.2%). We found a new type in 38 sites (26.8%) that constituted a fourth type. Conclusion: We found that type III was the most common variant. In the fourth type, the IAN was not detectable because the main nerve was adjacent to the cortical plate and the incisive branch was thinner than the main branch and alongside it. In this type, more care is needed for surgeries including inferior alveolar and mental nerve transposition.