• Journal of information and communication convergence engineering
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• v.17 no.2
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• pp.91-96
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• 2019

In this study, a system to increase the expressiveness of existing standard terminology using three-dimensional (3D) data is designed. We analyze the existing medical terminology system by searching the reference literature and perform an expert group focus survey. A human body image is generated using a 3D modeling tool. Then, the anatomical position of the human body is mapped to the 3D coordinates' identification (ID) and metadata. We define the term to represent the 3D human body position in a total of 12 categories, including semantic terminology entity and semantic disorder. The Blender and 3ds Max programs are used to create the 3D model from medical imaging data. The generated 3D human body model is expressed by the ID of the coordinate type (x, y, and z axes) based on the anatomical position and mapped to the semantic entity including the meaning. We propose a system of standard terminology enabling integration and utilization of the 3D human body model, coordinates (ID), and metadata. In the future, through cooperation with the Electronic Health Record system, we will contribute to clinical research to generate higher-quality big data.

• Proceedings of the Korea Information Processing Society Conference
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• 2023.11a
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• pp.563-565
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• 2023

Acupuncture and acupressure apply needles or pressure to anatomical points for therapeutic benefit. The over 350 mapped acupuncture points in the human body can each treat various conditions, but anatomical variations make precisely locating these acupoints difficult. We propose a computer vision technique using the real-time hand and face tracking capabilities of the MediaPipe framework to identify acupoint locations. Our model detects anatomical facial and hand landmarks, and then maps these to corresponding acupoint regions. In summary, our proposed model facilitates precise acupoint localization for self-treatment and enhances practitioners' abilities to deliver targeted acupuncture and acupressure therapies.

• Journal of Mechanical Science and Technology
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• v.15 no.7
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• pp.995-1001
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• 2001

The finite element human head model is developed for traumatic injury assessment. The model is constructed based on the precise anatomical geometry and validated with test results. In this paper, structural and physiologic explanation of human head will be introduced as well as the modeling methodology. Some of simulation results are also chosen to present major features of the model.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.171-172
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• 1995

In this paper, an anatomical labeling system for assisting localization of region of interest on human brain imaging is represented. Model image for labeling anatomical name on the other image is Atlas. Object image to be labeled, such as CT, MR, and PET, is registered onto Atlas. And then, anatomical name for region of interest is appeared on a window by clicking mouse button on object image. The same part named anatomically on that region is labeled and drawn on object image.

• Journal of Mechanical Science and Technology
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• v.15 no.7
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• pp.982-994
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• 2001

Commercially available software packages permit to position human models of various geometries in practical scenarios while respecting the anatomical constraints of the skeletal joints and of the bulk of the bodies. Beyond such features, the PAM-Comfort(sup)TM software has been conceived to provide direct access to the muscular forces needed by humans to perform physical actions where muscle force is required. The PAM-Comfort(sup)TM human models are made of multi-body linked anatomical skeletons, equipped with finite elements of the relevant skeletal muscles. The hyper-static problem of determination of muscle forces is solved by optimisation technique. Voluntary stiffening of muscles can be added to the basic contraction levels needed to perform a specific task. The calculated muscle forces obey Hills model. The model and software have been applied in several interesting scenarios of various fields of application, such as car industry, handling of equipment and sports activities.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.11 s.176
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• pp.182-189
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• 2005

The human knee joint is the intermediate joint of the lower limb that is the largest and most complex joint in the body. Understanding of joint-articulating surface motion is essential for the joint wear, stability, mobility, degeneration, determination of proper diagnosis and so on. However, many studies analyzed the passive motion of the lower limb because of the skin marker artefact and some studies described medial and lateral condyle of a femur as a simple sphere due to the complexity of geometry. Thus, in this paper, we constructed a three-dimensional geometric model of the human knee from the geometry of its anatomical structures using non-uniform B-spline surface fitting as a study for the kinematic analysis of more realistic human knee model. In addition, we developed and verified 6-DOF contact model of the human knee joint using $C^2$ continuous surface of the inferior region of a femur, considering the relative motion of shank to thigh during locomotion.

• Korean Journal of Computational Design and Engineering
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• v.16 no.6
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• pp.458-466
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• 2011

The morphology of a bone is closely associated with its biomechanical response. Thus, much research has been focused on analyzing the effects of variation of bone morphology with subject-specific models. Subject-specific models, which are generally achieved from 3D imaging devices like CT and MRI, incorporate more of the detailed information that makes a model unique. Hence, it may predict individual responses more accurately. Despite these powerful characteristics, specific models are not easily parameterized to the extent possible with statistical models because of their morphologic complexities. Thus, it is still proven challenging to analyze morphologic variations of subject-specific models across changes due to aging or disease. The aim of this article is to propose a generic and robust parametric morphing method for a subject-specific bone structure. We demonstrate this by using the proposed method on a model of a human proximal femur. Automatic segmentation algorithms are also presented to parameterize the specific model efficiently. A total of 48 femur models were evaluated for defining morphing vector fields. Also, several anatomical and mechanical functions of femur were considered as morphing constraints, and the NURBS interpolating technique was applied in the method to guarantee the generality of our morphed results.

• Clinical and Experimental Reproductive Medicine
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• v.48 no.3
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• pp.245-254
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• 2021

Objective: In humans, polycystic ovary syndrome (PCOS) is an androgen-dependent ovarian disorder. Aberrant gene expression in folliculogenesis can arrest the transition of preantral to antral follicles, leading to PCOS. We explored the possible role of altered gene expression in preantral follicles of estradiol valerate (EV) induced polycystic ovaries (PCO) in a mouse model. Methods: Twenty female balb/c mice (8 weeks, 20.0±1.5 g) were grouped into control and PCO groups. PCO was induced by intramuscular EV injection. After 8 weeks, the animals were killed by cervical dislocation. Blood serum (for hormonal assessments using the enzyme-linked immunosorbent assay technique) was aspirated, and ovaries (the right ovary for histological examinations and the left for quantitative real-time polymerase) were dissected. Results: Compared to the control group, the PCO group showed significantly lower values for the mean body weight, number of preantral and antral follicles, serum levels of estradiol, luteinizing hormone, testosterone, and follicle-stimulating hormone, and gene expression of TGFB1, GDF9 and BMPR2 (p<0.05). Serum progesterone levels were significantly higher in the PCO animals than in the control group (p<0.05). No significant between-group differences (p>0.05) were found in BMP6 or BMP15 expression. Conclusion: In animals with EV-induced PCO, the preantral follicles did not develop into antral follicles. In this mouse model, the gene expression of TGFB1, GDF9, and BMPR2 was lower in preantral follicles, which is probably related to the pathologic conditions of PCO. Hypoandrogenism was also detected in this EV-induced murine PCO model.

• Journal of Biomedical Engineering Research
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• v.25 no.6
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• pp.537-543
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• 2004

In order to create three-dimensional model for human body, a method that reconstructs geometric models from contour lines on cross-section images is commonly used. We can get a set of contour lines by acquiring CT or MR images and segmenting anatomical structures. Previously proposed method divides entire contour line into simply matched regions and clefts. Since long processing time is required for reconstructing cleft regions, its performance might be degraded when manipulating complex data such as cross-sections for human body. In this paper, we propose a fast reconstruction method. It generates a triangle strip with single tiling operation for simple region that does not contain branch structures. If there exist branches in contour lines, it partitions the contour line into several sub-contours by considering the number of vertices and their spatial distribution. We implemented an automatic surface reconstruction system by using our method which reconstructs three-dimensional models for anatomical structures.

• Journal of International Society for Simulation Surgery
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• v.4 no.1
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• pp.9-12
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• 2017

Purpose Surgery for separating craniopagus twins involves many critical issues owing to complex anatomical features. We demonstrate a 3D printed model and virtual reality (VR) technologies that could provide valuable benefits for surgical planning and simulation, which would improve the visualization and perception during craniopagus surgery. Material & Methods We printed a 3D model extracted from CT images of craniopagus patients using segmentation software developed in-house. Then, we imported the 3D model to create the VR environment using 3D simulation software (Unity, Unity Technologies, CA). We utilized the HTC Vive (HTC & Valve Corp) head-mount-display for the VR simulation. Results We obtained the 3D printed model of craniopagus patients and imported the model to a VR environment. Manipulating the model in VR was possible, and the 3D model in the VR environment enhanced the application of user-friendly 3D modeling in surgery for craniopagus twins. Conclusion The use of the 3D printed model and VR has helped understand complicated anatomical structures of craniopagus patients and has made communicating with other medical surgeons in the field much easier. Further, interacting with the 3D model is possible in VR, which enhances the understanding of the craniopagus surgery as well as the success rate of separation surgery while providing useful information on diagnosing and surgery planning.