• Title/Summary/Keyword: Analytical results

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Factors Affecting the Morbidity Related to Respiratory Dieseases in Urban Korea (한국 도시의 만성호흡기 질환 이환율에 영향을 주는 요인)

  • Han, Sung-Hyun;Park, Jae-Sung;Seo, Seung-Hee;Yoon, Jee-Eun;Jee, Sun-Ha
    • Korea journal of population studies
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    • v.28 no.2
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    • pp.205-217
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    • 2005
  • Purpose: To evaluate the factors affecting hospital utilization for respiratory diseases by ecological study design and GIS tool. To raise the social concern for respiratory disease by the result. Methods: Hospital admission data supported by national health insurance cooperation were transformed to spread sheet data format and combined with air monitoring dataset. Air pollution data were collected from the annual report of air monitoring published by Korea Ministry of Environment. Socioeconomic statistics including population density, age distribution, forest ratio etc.. were filed using Korea National Statistical Office database. Multiple linear regression analysis was performed to evaluate the factors affecting hospital utilization for respiratory diseases. Analytical unit was 52 cities. Results: The factors affecting hospital utilization for respiratory diseases were the proportion of population 60 years and over, seaside city, $O_3$ level, smoking rate. Conclusions: However, outdoor pollutants monitoring data and smoking rate have weakness in reflecting individual exposure. Further research is required to propose more illustrative means to evaluate causal relationship between air pollution and respiratory health effect factors.

Sensitivity Analysis and Estimation of the Depth of Investigation in Small-Loop EM Surveys (소형루프 전자탐사의 감도분석 및 가탐심도 추정)

  • Song Yoonho;Chung Seung-Hwan
    • Geophysics and Geophysical Exploration
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    • v.5 no.4
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    • pp.299-308
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    • 2002
  • We have derived an analytical expression for the sensitivity of the frequency domain small-loop electromagnetic (EM) surveys over a two-layer earth in order to estimate the depth of investigation with an instrument having the source-receiver separation of about 2 m. We analyzed the sensitivities to the lower layer normalized by those to the upper half-space and estimated the depth of investigation from the sensitivity analyses and the mutual impedance ratio. The computational results showed that the in-phase components of the sensitivity to the lower layer dominates those to the upper layer when the thickness of the upper layer is less than 20 m, while the quadrature components are not sensitive to the lower layer over the entire frequency range. Hence we confirmed that the accurate measurement of the in-phase component is essential to increase the depth of investigation in the multi-frequency small-loop EM survey. When conductive basement of 10 ohm-m underlies the upper layer of 100 ohm-m, an accurate measurement of the in-phase components ensures the depth of the investigation more than 10 m even accounting a noise effect, from which we conclude that the small-loop EM survey is quite effective in imaging the conductive plume down to a considerable depth. On the other hand, in the presence of the resistive basement of 1,000 ohm-m, the depth of investigation may not exceed 5 m considering the instrumental accuracy, which implies that the application of the small-loop EM survey is not recommended over the resistive environment other than detecting the buried conductor.

A Study on the Improvement of Dietary Protein-efficiency by Supplement of the Panax Ginseng-by-products. (인삼의 부산물을 이용한 식의성 단백질의 효율 향상을 위한 연구)

  • 황우익;이성동
    • Journal of Ginseng Research
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    • v.3 no.1
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    • pp.1-34
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    • 1979
  • Our nation is confronted with the situation that the rice, a principal food, short of some essential amino acids, leads to imbalanced meals insufficient in the nutrient of Protein, to bring many difficulties in the elevation of nutritional state in our nation. While. our country has been produced much amounts of Panax Ginseng roots which has a stimulating effects on the metabolism of protein, lipid and nucleic acids in the body. And the leaf and trunk of Panax Ginseng were also produced a considerable amounts as the by-products. Author believe that these by-products (leaf and trunk) of Panax Ginseng might have some components possessing simillar activity with Panax Ginseng root although the quantity and qualify of the functional components may more or less be different. Therefore, this study was demised to observe the supplemental effect of the Panax Ginseng-by-Products on the dietary protein efficiency and nutritional state of rats. The feeds used for this experiment were rice containing 30% barely, fish four, and the leaf, trunk and small root of the Panax Ginseng, and the contents of the general nutrients including protein, lipid and carbohydrate etc. in each feed were analyzed for the combination of each feed. And, being based on analytical values of Protein in food. fish Pour as Protein source was added were rice containing 30% barely to be include 8.6 to 8.7%, 12%, 15% and 18% of protein. Then 2% of the leaf, trunk or small reef of Panax Ginseng was supplemented into each of above protein diet group, ton 16 kinds of diets were Prepared. The male albino rats from a Pure strain, weighing 70g to 80g. were used for experimental animals. They were maintained with coresponding fist for f and 8 weeks, and the growth rate, consumption of diets and protein, efficiency of feed and Protein in animals were determined. The lipids, proteins and cholesterols in serum and liver were also determined quantitatively after they were sacrificed in coresponding term. The results obtained are summarized as follows: 1. Body weigh of diet group containing 8.6 to 8.7%,12%, and 15% of protein are increased remarkably by supplement of 2% of the leaf or small root of Panax Ginseng in comparison with each of controls. But this tendency could not observed in diet group containing 18eA Proteins. 2. Feed efficiency showed same tendency in comparison with changes of gained body weight. Specially, in each of diets containing 8.7%, 12%, 15% and 18% of Proteins, supplement of the leaf of Panax Ginseng showed the better feed efficiency than supplement of the trunk or small root. 3. In feeding group for 8 weeks, protein efficiency showed worst efficiency in diet containing 18% proteins and showed the best efficiency was the diet group containing 12% Proteins. And the efficiency was improved according to supplement of the leaf of Panax Ginseng. 4. Nitrogen contents in serum and liver did not show large differences each other in all diet groups. But contexts of total cholesterol and 1ipid were decreased markedly in diet groups containing 12%, 15% and 18% of proteins in comparison with diet group containing 8.6% to 8.8% of proteins.

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Stereoisomer-specific ginsenoside 20(S)-Rg3 reverses replicative senescence of human diploid fibroblasts via Akt-mTOR-Sirtuin signaling

  • Yang, Kyeong-Eun;Jang, Hyun-Jin;Hwang, In-Hu;Hong, Eun Mi;Lee, Min-Goo;Lee, Soon;Jang, Ik-Soon;Choi, Jong-Soon
    • Journal of Ginseng Research
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    • v.44 no.2
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    • pp.341-349
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    • 2020
  • Background: The replicative senescence of human dermal fibroblasts (HDFs) is accompanied by growth arrest. In our previous study, the treatment of senescent HDFs with Rg3(S) lowered the intrinsic reactive oxygen species (ROS) levels and reversed cellular senescence by inducing peroxiredoxin-3, an antioxidant enzyme. However, the signaling pathways involved in Rg3(S)-induced senescence reversal in HDFs and the relatedness of the stereoisomer Rg3(R) in corresponding signaling pathways are not known yet. Methods: We performed senescence-associated β-galactosidase and cell cycle assays in Rg3(S)-treated senescent HDFs. The levels of ROS, adenosine triphosphate (ATP), and cyclic adenosine monophosphate (cAMP) as well as the mitochondrial DNA copy number, nicotinamide adenine dinucleotide (NAD)+/1,4-dihydronicotinamide adenine dinucleotide (NADH) ratio, and NAD-dependent sirtuins expression were measured and compared among young, old, and Rg3(S)-pretreated old HDFs. Major signaling pathways of phosphatidylinositol 3-kinase/Akt, 5' adenosine monophosphate-activated protein kinase (AMPK), and sirtuin 1/3, including cell cycle regulatory proteins, were examined by immunoblot analysis. Results: Ginsenoside Rg3(S) reversed the replicative senescence of HDFs by restoring the ATP level and NAD+/NADH ratio in downregulated senescent HDFs. Rg3(S) recovered directly the cellular levels of ROS and the NAD+/NADH ratio in young HDFs inactivated by rotenone. Rg3(S) mainly downregulated phosphatidylinositol 3-kinase/Akt through the inhibition of mTOR by cell cycle regulators like p53/p21 in senescent HDFs, whereas Rg3(R) did not alter the corresponding signaling pathways. Rg3(S)-activated sirtuin 3/PGC1α to stimulate mitochondrial biogenesis. Conclusion: Cellular molecular analysis suggests that Rg3(S) specifically reverses the replicative senescence of HDFs by modulating Akt-mTOR-sirtuin signaling to promote the biogenesis of mitochondria.

An Importance Analysis of National Competency Standard for 4-year College Information Systems Development Curriculum (국가직무능력표준(NCS)의 4년제대학 정보시스템개발 교육과정을 위한 중요도분석연구)

  • Kim, Jae Kyung
    • Journal of Korea Society of Industrial Information Systems
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    • v.22 no.4
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    • pp.117-129
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    • 2017
  • The Purpose of this Study is to Identify the Learning Modules of the National Competency Standard (NCS) Related to the Information Systems Development Curriculum of 4-year Colleges, to Explore the Possibility of Applying NCS to the Curriculum, and to Examine Implications. The Importance of 26 Competency Units in the Applied SW Engineering of NCS was Compared by Area Experts Composed of 14 Information Systems Developers and Professors of 7 Universities who Teach Software Engineering Subjects Through the Hierarchical Analysis Process (AHP). The Results of the Study as Follows. First, the Relative Importance of the Competency Elements was in order of 'Confirming the Requirements', 'Checking the UI Requirements', 'Designing the Physical Data Repository', 'Testing Developer Integration', and 'Fixing Developer Defects'. Second, while the Entry and Intermediate Level Developer Group Determined that the Competency Elements Related to the IS Development Implementation Stage is more Important, the Advanced IS Developer Groups Consider the Competency Elements Related to the Theory-oriented Design Stage as Important Competency. In Addition, the Group of College Professors was Found to Choose all the Practical and Theoretical Competency Elements that Two Developers Groups Considered Important. Implications of the Study Suggested that the Job Performance Competence and Quality of Education Related to IS Development can be Enhanced.

Studies on Relation of Nitrate and Nitrite Contents in Korean Foods and Human Saliva (한국(韓國) 식품(食品)과 인(人) 타액중(唾液中)의 질산염(窒酸鹽) 및 아질산염(亞窒酸鹽)의 함량(含量) 관계(關係)에 관(關)한 연구(硏究))

  • Ko, Young-Su
    • Korean Journal of Food Science and Technology
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    • v.11 no.3
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    • pp.147-152
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    • 1979
  • Nitrite, one of the precursors of dimethylnitrosamine, distributes widely in natural foods and is also used as a color fixing agent in meat products. This experiment was carried out to determine the contents of nitrite and nitrate of Korean foods and suman saliva. Nitrite content was measured by use of the diazotization-coupling reaction, while cadmium reduction method by use of metallic cadmium was applied to determine nitrate. The objects are about 150 of female students who are $19{\sim}22$ years old ands standard analytical values of nitrate contents of $10{\sim}20$ samples produced in various places. The results showed that contents of nitrite and nitrate of Korean foods and saliva were relatively high levels.

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Prediction on the Quality of Forage Crop Seeded in Spring by Near Infrared Reflectance Spectroscopy (NIRS) (근적외선 분광법에 의한 춘계 파종 사초의 성분추정)

  • Lee, Hyo-Won
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.31 no.4
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    • pp.409-414
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    • 2011
  • This study was conducted to find out an alternative way of rapid and accurate analysis of forage quality. Near Infrared Reflectance Spectroscopy (NIRS) was used to evaluate the possibility of forage analysis. 175 samples consisted of Italian ryegrass, whole crop barley and pea seeded spring in 2009 were collected. The samples were analyzed for moisture, crude protein (CP), crude ash (CA), acid detergent fiber (ADF), and neutral detergent fiber (NDF), and also scanned using NIRSystem with wavelength from 400~2,500 nm. Multiple linear regression was used with wet analysis data for developing the calibration model and validated unknown samples. The important index in this experiment were SEC, SEP. The r2 value for moisture, CP, CA, ADF, and NDF in calibration set was 0.65, 0.97, 0.93, 0.99, and 0.97 and also was 0.15, 0.94, 0.96, 0.98 and 0.98 in validation set, respectively. The results of this experiment indicates that NIRS was reliable analytical method to assess forage quality for CP, CA ADF and NDF except moisture content in forage when proper samples incorporated into the equation development.

A Study of Theoretical Methods for Estimating Void Ratio Based on the Elastic Wave Velocities (탄성파 속도를 이용한 간극비 산출 식의 고찰)

  • Lee, Jong-Sub;Park, Chung-Hwa;Yoon, Sung-Min;Yoon, Hyung-Koo
    • Journal of the Korean Geotechnical Society
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    • v.29 no.2
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    • pp.35-45
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    • 2013
  • The void ratio is an important parameter for reflecting the soil behavior including physical property, compressibility, and relative density. The void ratio can be obtained by laboratory test with extracted soil samples. However, the specimen has a possibility to be easily disturbed due to the stress relief when extracting, vibration during transportation, and error in experimental process. Thus, the theoretical equations have been suggested for obtaing the void ratio based on the elastic wave velocities. The objective of this paper is to verify the accuracy of the proposed analytical solution through the error norm. The paper covers the theoretical methods of Wood, Gassmann and Foti. The elastic wave velocity is determined by the Field Velocity Probe in the southern part of Korean Peninsular. And the rest parameters are assumed based on the reference values. The Gassmann method shows the high reliability on determining the void ratio. The error norm is also analyzed as substitution of every parameter. The results show every equation has various characteristics. Thus, this paper may be widely applied for obtaining the void ratio according to the field condition.

Analytical Evaluation on Soil Slope Reinforced by Pressure Grouted Protrusion Type Soil Nailing (가압식 돌기네일에 의해 보강된 토사 비탈면의 해석적 평가)

  • Hong, Cheor-Hwa;Lee, Sang-Duk
    • Journal of the Korean Geotechnical Society
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    • v.33 no.7
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    • pp.5-16
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    • 2017
  • Soil nailing is the most general method to reinforce the slope by taking pullout and shear resistance force of the nail for stabilizing the slope. Domestic soil nailing design method considers only pullout resistance and does not consider the shear resistance sufficiently. In case of nail, the effect of tensile stress is dominant, but it is desirable to design by considering shear stress as well as tensile stress in case of slope where circle failures occur. Recently, studies on the shear resistance effect of nails have been carried out in the geotechnical field. However, many researches on the shear reinforcement effect of soil nailing have not been conducted until now. Most of the studies are about increasing pullout resistance by improving material, shape and construction method of nail. Therefore, it is necessary to the study on shear resistance of soil nailing and development of new methods to increase the shear force. In this study, large shear test and limit equilibrium analysis have been performed for a new soil nailing method to increase the shear resistance by forming protrusions through pressurized grouting after installing a packer on the outside of deformed bar. The study results showed that shear resistance of protrusion type soil nailing increased compared to soil nailing and it is more effective when applied to the ground with large strength parameters.

RC Wall under Axial Force and Biaxial Bending Moments (축력과 면내 및 면외 휨모멘트를 받는 철근콘크리트 벽체)

  • 박홍근
    • Magazine of the Korea Concrete Institute
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    • v.10 no.4
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    • pp.113-124
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    • 1998
  • Numerical study using nonlinear finite element analysis is done for investigating behavior of isolated reinforced concrete walls subject to combined in-plane and out-of-plane bending moments and axial force. A method for estimating the ultimate strength of wall is developed, based on the analytical results. For the nonlinear finite element analysis, a computer program addressing material and geometric nonlinearities is developed. An existing unified method combining plasticity theory and damage model is used for material model of reinforced concrete. By numerical studies, the internal force distribution in the cross section is idealized, and a new method for estimating the ultimate strength of wall is developed. According to the proposed method, variation of the interaction curve of in-plane bending moment and axial force depends on the range of the permissible axial force per unit length that is determined by the given amount of out-of-plane bending moment. As the out-of-plane bending moment increases, the interaction curve shrinks, which indicates a decrease in the ultimate strength. The proposed method is compared with an existing method using the general assumption that strain shall be directly proportional to the distance from the neutral axis. Compared with the proposed method, the existing method overestimates the ultimate strength for walls subject to low out-of-plane bending moments, and it underestimates the ultimate strength for walls subject to high out-of-plane bending moments.