• Journal of The Korean Society of Inherited Metabolic disease
• /
• v.2 no.1
• /
• pp.7-11
• /
• 2002

Isovaleric acidemia is an inborn error in metabolism due to a defect in isovaleryl-CoA dehydrogenase. Accumulation of serum isovaleric acid causes poor feeding, vomiting, lethargy, hypothermia, convulsion, mental retardation, etc. It is inherited as an autosomal recessive trait. Since the first reports of isovaleric acidemia by Tanaka et al in 1966, more than 60 cases have been reported. There are two clinically different presentations of isovaleric acidemia, with about half the patients presenting with an acute severe neonatal form and about half with a chronic intermittent form. The difference in clinical presentation may not be a consequence of differing severities of the causative mutation, but a result of the timing of application of catabolic stress or the ability to form isovalerylglycine. We described here clinical and organic acid analytical findings of in 3 cases isovaleric acidemia.

• Proceedings of the Earthquake Engineering Society of Korea Conference
• /
• 1999.10a
• /
• pp.186-192
• /
• 1999

Safety-related equipments of nuclear power plant must be seismically qualified to demonstrate their ability to function as required during and/or after the earthquake, The seismic qualification is usually achieved through analysis and testing. Analysis method is preferably adopted for structurally simple equipments which are easy to be mathematically modeled. However even for relatively complex equipments analysis method is occasionally used for computing the input motion or supporting information for the component test followed. Electrical cabinet is a typical example for which analysis method is combinedly used with test to get modal properties of the enclosing cabinet structure. Usually the structural elements and doors of the cabinet are loosely interconnected with small-size bolts or spot welding. Therefore cabinet-type equipment usually has high and complex nonlinear properties which are not easily idealized by simple practical modeling techniques. in this paper with respect to a typical cabinet-type structure(instrumentation cabinet of nuclear power plant) a comparative study has been performed between three different state-of-the -art modeling techniques: lumped mass model frame model and FEM modal. Form the study results it has been found that modal properties of the cabinet-type structure in the elastic behavior range can be reasonably computed through any type of modeling techniques in the practice with slight modification of model properties to get better accuracy. However it needs additional modeling techniques to get reasonable results up to nonlinear range.

• Magazine of the Korean Society of Agricultural Engineers
• /
• v.38 no.6
• /
• pp.35-41
• /
• 1996

The theory of consolidation has been achieved remarkable development in terms of theory such as finite consolidation theory, two dimensional Rendulic consolidation theory. Though those theories are well defined, the analysis is by no means straightforward, because associated properties are very difficult to determine in the laboratory, Therefore Terzaghi's one dimensional consolidation theory and Barron's cylindrical consolidation theory are still widely used in engineering practice. The theoretical shortcomings of those consolidation theories and uncertainties of associated properties make inevitably some discrepancy between theoretical and field settlements. Field settlement measurement by settlement plate is, therefore, widely used to overcome the discrepancy. Ultimate settlement is one of the most important factor of embankment construction on soft soils. Nowadays the ultimate settlement prediction methods using field settlement data are widely accepted as a helpful tool for field settlement analysis of embankment construction on soft soils. Among the various methods of ultimate settlement prediction, hyperbolic method and Asaoka's method are most commonly used because of their simplicity and ability to give a reasonable estimate of consolidation settlement. In this paper, the reliability of hyperbolic method and Asaoka's method has been examined using analytical methods. It is shown that both hyperbolic method and Asaoka's method are significantly affected by the direction of drainage.

• The Journal of Industrial Distribution & Business
• /
• v.6 no.2
• /
• pp.13-16
• /
• 2015

Purpose - Benford's Law is a simple and effective auditor tool that detects fraud. This paper's purpose is to audit the efficiency of Benford's law, which uses a set of strange observations, certain numbers repeated over other numbers in the data set. Research design, data, and methodology - Benford's law was applied in numerical analysis. We can say that in addition to reducing the duration of the audit, the capacities of the audit were more robust. Results - Sample auditse valuated the ability of auditors to prove fraud and expand the use of analytical procedures in planning the audit. Additionally, the use of the analyses as part of the computer's internal controls helped to further improve the effectiveness of internal controls and reinforce them. Conclusions - Benford analysis should be carried out as appropriate. In subsequent studies, it can also be examined as a tool to reveal doubtful accounts. Numerical analysis of the data and a computer are necessary. Programs for data analysis in various applications such as auditing (SAS) and (ACL) and (Case Ware) and (IDEA) are available.

• The Journal of Asian Finance, Economics and Business
• /
• v.7 no.11
• /
• pp.147-156
• /
• 2020

This study aims to analyze the effect of public spending, macroeconomic variables, and BPK opinion on economic growth. This study is motivated by the inequality of fiscal policy effectiveness between regions in Indonesia in influencing the economic growth of different regions, the ability of local governments to attract foreign investors, and the transparency of regional financial management in designing development programs to encourage regional economic growth. The analytical tool in this study is a dynamic panel regression model with data from 2008 to 2017. The results of this study show that, in the short term, the population affects regional economic growth, while in the long term, the economic growth is affected by the number of people, the poor, General Allocation Fund, health budget, foreign investment and BPK opinion. The findings of this study are that in the long term the General Allocation Fund becomes an obstacle to economic growth, this is because the general allocation funds is widely used to cover the lack of funds for routine regional activities, thereby reducing activities for development programs. Another research finding is that fiscal policies carried out by local governments make a small and ineffective contribution to promoting economic growth.

• ETRI Journal
• /
• v.34 no.2
• /
• pp.226-234
• /
• 2012

The novelty of this study resides in the fabrication of stoichiometric and stress-reduced $Si_3N_4/SiO_2/Si_3N_4$ triple-layer membrane sieves. The membrane sieves were designed to be very flat and thin, mechanically stress-reduced, and stable in their electrical and chemical properties. All insulating materials are deposited stoichiometrically by a low-pressure chemical vapor deposition system. The membranes with a thickness of 0.4 ${\mu}m$ have pores with a diameter of about 1 ${\mu}m$. The device is fabricated on a 6" silicon wafer with the semiconductor processes. We utilized the membrane sieves for plasma separations from human whole blood. To enhance the separation ability of blood plasma, an agarose gel matrix was attached to the membrane sieves. We could separate about 1 ${\mu}L$ of blood plasma from 5 ${\mu}L$ of human whole blood. Our device can be used in the cell-based biosensors or analysis systems in analytical chemistry.

• International Journal of Control, Automation, and Systems
• /
• v.2 no.3
• /
• pp.279-288
• /
• 2004

This paper presents a novel design for a tubular linear brushless permanent-magnet motor. In this design, the magnets in the moving part are oriented in an NS-NS―SN-SN fashion which leads to higher magnetic force near the like-pole region. An analytical methodology to calculate the motor force and to size the actuator was developed. The linear motor is operated in conjunction with a position sensor, three power amplifiers, and a controller to form a complete solution for controlled precision actuation. Real-time digital controllers enhanced the dynamic performance of the motor, and gain scheduling reduced the effects of a nonlinear dead band. In its current state, the motor has a rise time of 30 ms, a settling time of 60 ms, and 25% overshoot to a 5-mm step command. The motor has a maximum speed of 1.5 m/s and acceleration up to 10 g. It has a 10-cm travel range and 26-N maximum pull-out force. The compact size of the motor suggests it could be used in robotic applications requiring moderate force and precision, such as robotic-gripper positioning or actuation. The moving part of the motor can extend significantly beyond its fixed support base. This reaching ability makes it useful in applications requiring a small, direct-drive actuator, which is required to extend into a spatially constrained environment.

• Bulletin of the Korean Chemical Society
• /
• v.24 no.1
• /
• pp.37-44
• /
• 2003

We examined the effect of polyether-type nonionic surfactants (Brij 35, Triton X-100, Tween 20 and Tween 80) on the potentiometric properties of sodium-, potassium- and calcium-selective membranes which are prepared with widely used ionophores and four kinds of polymer matrices [poly(vinyl chloride) (PVC), polyurethane (PU), PVC/PU blend, and silicone rubber (SR)]. It was found that the PVC-based membranes, which provide the best performance among all other matrix-based membranes in the absence of nonionic surfactants, exhibited larger change in their potentiometric properties when nonionic surfactants are added to the sample solution. On the other hand, the sodium-selective SR-based membrane with calix[4]arene, potassium-selective PVC/PU- or SR-based membrane with valinomycin, and the calcium-selective SR-based membrane with ETH 1001 provide almost identical analytical performance in the presence and absence of Tween 20 or Tween 80 surfactants. The origin of nonionic surfactants effect was also investigated by interpreting the experimental results obtained with various matrices and ionophores. The results suggest that the nonionic surfactant extracted into the membrane phase unselectively form complexes with the primary and interfering ions, resulting in increased background potential and lower binding ability for the ionophore. Such effects should result in deteriorated detection limits, reduced response slopes and lower selectivity for the primary ions.

• Journal of Contemporary Eastern Asia
• /
• v.16 no.2
• /
• pp.20-43
• /
• 2017

While the Internet has been used to galvanise people for the collective good, many have voiced concerns over the noise and vitriol present online and polarisation. In Singapore where the government regulates traditional mainstream media such as print and broadcast, the online space has been described as a "Wild Wild West" rife with rumours, untruths and misinformation. Such developments do not only exert a potential negative effect on the deliberative nature of public discourse but also skew bias towards the online space, affecting the ability of online users to communicate with authority and power. This study seeks to examine the rationality of the cyberspace through using a new "rationality" framework to analyse political discourse online. Comprising objectivity, emotionality and partisanship, the rationality framework was applied to a content analysis of 197 blogs with political content in 2014. The analysis indicated that the online political space was not the Wild Wild West that it was touted to be with significant levels of objectivity and non-partisanship. There was a stark absence of emotional discourse, and relationships were observed between bloggers' anonymity and rationality. Cognisant of academia's and policymakers' interest on the quality and effects of online discourse, the proposed analytical framework and the study findings hold implications for both developed and developing countries.

• Journal of the Korean Chemical Society
• /
• v.29 no.3
• /
• pp.220-225
• /
• 1985

An attempt was made to determine some trace metals in highly concentrated samples using micro sampling technique in flame atomic absorption spectrophotometry. Major instrumental parameters and optimun analytical conditions investigated were the measuring time of instrument (the speed of electronics), sample volume, burner height, aspiration rate, and fuel to oxidant ratio. Advantages of the present technique are not only rapid, simple, and sensitive with good precision but also capability of analyzing small volume of sample and ability to handle highly concentrated samples without serious burner clog-up problem compared to conventional flame atomic absorption.