• 제목/요약/키워드: Analysis of Variance Test

검색결과 2,483건 처리시간 0.034초

시판 이소니아짓 정제의 생물학적 동등성시험에 관한 연구 (Studies on the Bioequivalence Test of Isoniazid Tablets)

  • 최준식;안선엽
    • 약학회지
    • /
    • 제33권4호
    • /
    • pp.229-236
    • /
    • 1989
  • Even though two different preparations are chemically equivalent, the variance of bioavailability differenciates the clinical effect of preparations, so that the preparations need to be evaluated by comparing bioavailability in vivo as well as chemical equivalence. In this study, bioequivalence tests of commercially available isoniazid tablets A, B, C and D (standard) were performed to give some guidelines to bioequivalence test. The bioavailability parameters obtained by drug administeration were statistically analyzed. Statistical evaluation of the data involved an analysis of variance for a cross over design. Cross over design was employed with 8 healthy volunteers. The results were within 20% difference of mean value in the AUC, Cmax, Tmax and amount of urinary excretion (Au) between standard and isoniazid tablets. The results of ANOVA showed no significant differences for 'group or sequence', but almost not for 'between subjects'. The tablet. A, B and D were within 20 min, but tablet C was within 50 min. Tablet A was biologically equivalent in the Au. tablet B biologically equivalent in the Au and AUC. Tablet C was biologically equivalent in the Au. The relationship between the dissolution rate and Au was significant.

  • PDF

아동의 건강 자기 결정 지표에 대한 타당성 조사 (Validity test of the Health Self-Determinism Index for Korean Children)

  • 홍경자;이은주;신희선
    • 모자간호학회지
    • /
    • 제3권2호
    • /
    • pp.85-94
    • /
    • 1993
  • The purpose of this study was to test the construct validity and reliability of the Health Self-Determinism Index for Children (HSDI-C), an instrument designed to measure intrinsic motivation in health behavior. An convenience sample of 558,7 to 13 years old children completed the Korean version of HSDI-C. The findings were as follows : 1. Construct validity was supported through factorial isolation of four theory-consistent subscales ; Internal-external cue responsive ness, Self-determinism in health judgement, Competency in health matters, and Self-determinism in health behavior /goal. The total percent of variance explained by 4 factors was 2 percent. 2. The correlations between the four factors were ranged from -.06 to .29 indicating that factors are not redundant and each factor contributes uniquely to the total construct. 3. Cronbach alpha coefficient for internal consistency was .96 for the total, and .72, .56, .69, and .75 on the respective subscales. Test-retest reliability for the total scale was .85 at 2 weeks. 4. The Analysis of variance for the HSDI-C total scale and subscales according to grades revealed that there were significant differences in means for the total and factor one and two, indicating younger children were more extrinsically motivated.

  • PDF

Optimum time-censored ramp soak-stress ALT plan for the Burr type XII distribution

  • Srivastava, P.W.;Gupta, T.
    • International Journal of Reliability and Applications
    • /
    • 제15권2호
    • /
    • pp.125-150
    • /
    • 2014
  • Accelerated life tests (ALTs) are extensively used to determine the reliability of a product in a short period of time. Test units are subject to elevated stresses which yield quick failures. ALT can be carried out using constant-stress, step-stress, progressive-stress, cyclic-stress or random-stress loading and their various combinations. An ALT with linearly increasing stress is ramp-stress test. Much of the previous work on planning ALTs has focused on constant-stress, step-stress, ramp-stress schemes and their various combinations where the stress is generally increased. This paper presents an optimal design of ramp soak-stress ALT model which is based on the principle of Thermal cycling. Thermal cycling involves applying high and low temperatures repeatedly over time. The optimal plan consists in finding out relevant experimental variables, namely, stress rates and stress rate change points, by minimizing variance of reliability function with pre-specified mission time under normal operating conditions. The Burr type XII life distribution and time-censored data have been used for the purpose. Burr type XII life distribution has been found appropriate for accelerated life testing experiments. The method developed has been explained using a numerical example and sensitivity analysis carried out.

  • PDF

수술실 간호사의 방사선 방어행위의 영향 요인 (Factors Affecting Radiation Protection Behaviors among Operating Room Nurses)

  • 김진;김진선;김현례
    • 성인간호학회지
    • /
    • 제28권6호
    • /
    • pp.680-690
    • /
    • 2016
  • Purpose: This study was designed to identify knowledge, attitude, environment, and self-efficacy among perioperative nurses in terms of radiation protection and to describe those factors affecting radiation protection behaviors. Methods: The sample was comprised of 128 perioperative nurses who agreed to participate in this descriptive study. Data were collected from a self-administered questionnaire and were analyzed using the t-test, analysis of variance, Mann-whitney U test, Kruskal-Wallis test, Pearson's correlation, and multiple regression analyses. Results: Radiation protection behaviors were significantly different by participant's gender, length of career as a perioperative nurse, educational level and prior experience with radiation protection education. Radiation protection behaviors were significantly correlated with radiation protection environment and self-efficacy in terms of radiation protection behaviors. In the multiple linear regression models, radiation protection environment and self-efficacy on radiation protection behaviors were statistically significant predictors of radiation protection behaviors, which accounted for 50.3% of variance in dependent variable. Conclusion: This study concluded that radiation protective environment in operating room is important to promote radiation protective behaviors and radiation safety management program to enhance self-efficacy is highly recommended.

우리나라 성인여성의 의복구매행동에 관한 실태 조사연구 (1) -서울, 부산, 대구지역을 중심으로- (A Study on the Clothing Buying Behaviors of Women -in Seoul, Busan, Daegu-)

  • 송미령
    • 한국의류학회지
    • /
    • 제12권1호
    • /
    • pp.53-68
    • /
    • 1988
  • The purpose of this study was to investigate the clothing buying behaviorial pattern and the differences of clothing buying behaviors by the demographic variables. For the measurement of clothing buying behavior, the researcher developed a questionnaire. This questionnaire was adjusted by preliminary test. Data were collected from 494 women dwelling in Seoul, Busan, Daegu. For statistical analysis, frequency, percentage, average, standard deviation, paired t-test, $X^2-test$, one way analysis of variance, Duncan's multiple range test were used. The results were as follows: 1. The $57\%$ of the subject group planned their clothing purchase in advance, ana their friends affected clothing buying behaviors more than other fashion information sources. The store in which the subject group purchased clothing most frequently was a department store. In clothing selection, hygienic factor and aesthetic factor were shown as important factors. 2, There were significant differences in clothing buying behaviors according to demographic variables.

  • PDF

반도체 공정에서의 Wafer Map Image 분석 방법론 (Wafer Map Image Analysis Methods in Semiconductor Manufacturing System)

  • 유영지;안대웅;박승환;백준걸
    • 대한산업공학회지
    • /
    • 제41권3호
    • /
    • pp.267-274
    • /
    • 2015
  • In the semiconductor manufacturing post-FAB process, predicting a package test result accurately in the wafer testing phase is a key element to ensure the competitiveness of companies. The prediction of package test can reduce unnecessary inspection time and expense. However, an analysing method is not sufficient to analyze data collected at wafer testing phase. Therefore, many companies have been using a summary information such as a mean, weighted sum and variance, and the summarized data reduces a prediction accuracy. In the paper, we propose an analysis method for Wafer Map Image collected at wafer testing process and conduct an experiment using real data.

국부 확률을 이용한 데이터 분류에 관한 연구 (A Study on Data Clustering Method Using Local Probability)

  • 손창호;최원호;이재국
    • 제어로봇시스템학회논문지
    • /
    • 제13권1호
    • /
    • pp.46-51
    • /
    • 2007
  • In this paper, we propose a new data clustering method using local probability and hypothesis theory. To cluster the test data set we analyze the local area of the test data set using local probability distribution and decide the candidate class of the data set using mean standard deviation and variance etc. To decide each class of the test data, statistical hypothesis theory is applied to the decided candidate class of the test data set. For evaluating, the proposed classification method is compared to the conventional fuzzy c-mean method, k-means algorithm and Discriminator analysis algorithm. The simulation results show more accuracy than results of fuzzy c-mean method, k-means algorithm and Discriminator analysis algorithm.

폐좌상의 정량분석 (Quantitative Analysis of Lung Contusion)

  • 오중환
    • Journal of Chest Surgery
    • /
    • 제27권10호
    • /
    • pp.833-837
    • /
    • 1994
  • Lung contusion due to blunt chest trauma is the most common lung injury and correlated with the clinical course and prognosis. Its diagnosis by CT[Computerized Tomogram] gives a more clear and understandable three dimensional view, by which we are able to measure the volume of the contused and entire lung. Other variables are arterial blood gas, number of rib fracture, presence of hemopneumothorax, sternal fracture and clavicle fracture, number of associated non-thoracic injuries, ventilator time and presence of pulmonary complication. Percentage[%] of lung contusion are expressed as mean $\pm$ standard deviation and data analysis was performed by means of multivariate repeated measures analysis of variance to detect significant differences in variables between positive thoracic injury group and negative group. The paired t-test was used. Differences of percentage of lung contusion between groups were assessed by one-way analysis of variance. Simple linear regression was used to perform correlation analysis in the number of rib fracture and ventilator time. A p value less than 0.05 was considered statistically significant. Pneumothorax and the number of associated other injuries affect the amount of lung contusion and pulmonary complication group has more contused lung volume. Arterial blood gas study shows no correlation with the amount of lung contusion statistically. The number of rib fracture correlated with the amount of lung contusion, which also correlated with ventilator time[r=0.56, p<0.05]. In conclusion, quantitative anlysis of lung contusion by CT predicts the clinical course and treatment such as ventilator care.

  • PDF

특성함수와 피로해석을 이용한 로워컨트롤암의 형상최적설계 (Shape Optimization of the Lower Control Arm using the Characteristic Function and the Fatigue Analysis)

  • 박영철;이동화
    • 한국자동차공학회논문집
    • /
    • 제13권1호
    • /
    • pp.119-125
    • /
    • 2005
  • The current automotive is seeking the improvement of performance, the prevention of environmental pollution and the saving of energy resources according to miniaturization and lightweight of the components. And the variance analysis on the basis of structure analysis and DOE is applied to the lower control am. We have proposed a statistical design model to evaluate the effect of structural modification by performing the practical multi-objective optimization considering weight, stress and fatigue lift. The lower control arm is performed the fatigue analysis using the load history of real road test. The design model is determined using the optimization of acquired load history with the fatigue characteristic. The characteristic function is made use of the optimization according to fatigue characteristics to consider constrained function in the optimization of DOE. The structure optimization of a lower control arm according to fatigue characteristics is performed. And the optimized design variable is D=47 m, T=36mm, W=12 mm. In the real engineering problem of considering many objective functions, the multi-objective optimization process using the mathematical programming and the characteristic function is derived an useful design solution.

국제물류에서 해운물류기업의 공급사슬성과 결정요인 (A Determinant Factors on Supply Chain Performance of Shipping and Logistics Firm in International Logistics)

  • 윤광운;배희성
    • 무역상무연구
    • /
    • 제30권
    • /
    • pp.3-26
    • /
    • 2006
  • Supply chain is viewed as a number of organizations(at least three) working cooperatively with at least some shared objectives. The concept of supply chain management represents the most advanced state in the evolutionary development of purchasing, procurement and other supply chain activities. This study aims to analyze and develop a measurement instrument for supply chain performance in international logistics. A measurement instrument for supply chain performance in international logistics are developed by Lai et al(2002). Supply chain reliability, customer service and cost are constructed reflecting service effectiveness and operations efficiency between shipper, forwarder and liner. The results of this study are as follow. We firstly tested the measurement properties of the sub-dimension of the supply chain performance construct using reliability test and confirmatory factor analysis follow by exploratory factor analysis. For each of the factor, reliability and validity are achieved because of the significant loading of the measurement items on their latent factors. Further research perform the analysis of variance by multi respondents within each firm and across partner firms in the supply chain. The result of analysis present the difference with shipper, forwarder and liner in statistics.

  • PDF