• 한국산업보건학회지
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• 제1권2호
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• pp.192-199
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• 1991

Biological exposure indices (BEI) of toluene, perchloroethylene (PCE) and methyl ethyl ketone (MEK) for Korean workers were studied respectively. Environmental exposures in workplace to organic solvent were measured by personal sampling. Blood toluene, blood perchloroethylene, urinary trichloroacetic acid and urinary MEK were determined by headspace gas chromatography. Urinary hippuric acid were determined by HPLC and corrected by creatinine. BEIs for Korean workers were calculated as the levels of determinants which are correspond to permissible exposure limits in Korea. Blood toluene level of 2.2mg/l and urinary hippuric acid level of 1.7g/g creatinine are correspond to an exposure of 100 ppm toluene. Blood PCE concentration of 1.6mg/l and urinary trichloroacetic acid concentration of 2.9mg/l are correspond to an exposure of 50ppm PCE. Urinary MEK concentration of 1.0mg/l is correspond to an exposure of 200ppm of MEK. BEIs for Korean workers determined in this study are very different to ACGIH's BEI as urinary determinants are much lower and blood determinants are much higher than ACGIH's BEI.

• 대한수의학회지
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• 제44권1호
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• pp.125-129
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• 2004

A 2-year-old, female, American cocker spaniel dog presented for a 1-year history of severe ascites, exercise intolerance, tachypnea. At that time, she was in an emergency state. First, the dog was stabilized with oxygen therapy. A diagnosis of cardiac problem was made from history, auscultation, radiograph, ECG, and echocardiography. Jugular pulsation was palpated and a harsh, systolic murmur of tricuspid regurgitation was prominent at the right cardiac apex. Tricuspid valve dysplasia (TVD) was confirmed with echocardiography, accompanying enormous myocardial hypertrophy. The clinical signs had been improved for 8 months with careful therapy and periodic abdominocentesis, and ascites was well controlled. The situation, however, became worse quickly in a week because the client did not follow our management schedule. Finally, she died due to dyspnea and shock. After the spontaneous death, necropsy and histopathological examination were performed and when we opened the thorax, a significantly large heart was observed. On histopathological findings, grossly myocardium appeared pale initially, then progressed to yellow and white. Microscopically, there was an extensive hemorrhage along with loss of myocardial striations. Interstitial fibrosis and various degenerative alterations in myocytes were also present.

• 과학기술학연구
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• 제13권2호
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• pp.37-70
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• 2013

기독교는 배아파괴로 인한 생명윤리문제를 들어 배아줄기세포연구에 반대하는 입장을 여러 차례 밝히고 신자들을 계도하고자 노력했으나 별다른 효과를 거두지 못했다. 이는 신자들의 태도결정에 교단의 입장 외에 다른 요인이 개입하고 있다는 것을 의미한다. 본 연구에서는 다양한 조사자료에 근거해 기독교 신자들이 배아 줄기세포에 대해 보이는 태도를 정리하고, 신자들의 태도형성에 영향을 미치는 요인을 동정하고자한다. 나아가 해당 요인들이 상호작용하는 과정, 신자들이 관련 정보를 해석하고 수용하는 과정에 보이는 특성 등을 정리하여, 배아연구에 대한 신자들의 태도결정에 종교적 요소가 미친 영향력이 제한적일 수밖에 없는 이유를 설명하고자한다.

• Membrane and Water Treatment
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• 제9권3호
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• pp.195-203
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• 2018

N-acetylcysteine (NAC) has been widely used as an initial mucolytic agent and is generally used as an antioxidant to help alleviate various inflammatory symptoms. NAC reduces bacterial extracellular polymeric substances (EPS) production, bacterial adhesion to the surface and strength of mature biofilm. The efficacy has been shown to inhibit proliferation of gram-positive and gram-negative bacteria. In membrane bioreactor (MBR) processes, which contain a variety of gram negative bacteria, biofilm formation has become a serious problem in stable operation. In this study, use of NAC as an inhibitor of biofilm contamination was investigated using the center for disease control (CDC) reactors with MBR sludge. Biomass reduction was confirmed with CLSM images of membrane surfaces by addition of NAC, which was more efficient as the concentration of NAC was increased to 1.5 mg/mL. NAC addition also showed decreases in EPS concentrations of the preformed biofilm, indicating that NAC was able to degrade EPS in the mature biofilm. NAC addition was also effective to inhibit biofilm formation by MBR sludge, which consisted of various microorganisms in consortia.

• Journal of Yeungnam Medical Science
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• 제34권2호
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• pp.149-160
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• 2017

Streptococcus pneumoniae, pneumococcus, is the most common cause of community-acquired pneumonia (CAP). CAP is an important infectious disease with high morbidity and mortality, and it is still one of the leading causes of death worldwide. Many genetic factors of the host and various environmental factors surrounding it have been studied as important determinants of the pathophysiology and outcomes of pneumococcal infections. Various cytokines, including transforming growth factor $(TGF)-{\beta}1$, are involved in different stages of the progression of pneumococcal infection. $TGF-{\beta}1$ is a cytokine that regulates a wide range of cellular and physiological functions, including immune and inflammatory responses. This cytokine has long been known as an anti-inflammatory cytokine that is critical to preventing the progression of an acute infection to a chronic condition. On the other hand, recent studies have unveiled the diverse roles of $TGF-{\beta}1$ on different stages of pneumococcal infections other than mitigating inflammation. This review summarizes the recent findings of the role of $TGF-{\beta}1$ on the pathophysiology of pneumococcal infections, which is fundamental to developing novel therapeutic strategies for such infections in immune-compromised patients.

• 한국멀티미디어학회논문지
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• 제7권7호
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• pp.934-943
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• 2004

본 논문에서는 웹에서 사용되는 쿠키를 안전하게 사용할 수 있도록 쿠키보호를 위해 쿠키 보호키 관리 시스템을 두고 사용자별로 다른 쿠키 보호키를 유지하게 함으로써, 쿠키 사용에 따른 사용자 정보의 무결성, 비밀성, 사용자 인증 서비스를 제공한다. 또한 웹 기술을 이용할 경우 노출된 URL을 이용해 내부 문서의 위치를 추측하고 접근하는 것을 방지하기 위해 URL을 노출시키지 않는 방법을 제시하였다. 본 시스템은 기업의 인트라넷에 적용함으로써 공격자에게 쉽게 정보 노출이 발생하는 취약한 쿠키의 안전함을 제공하고 내부사용자에 대한 내부문서 유출 문제를 최소화할 수 있을 것이다.

• Applied Microscopy
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• 제43권4호
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• pp.173-176
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• 2013

The oxidation behavior of the crystallized $Al_{87}Ni_3Y_{10}$ alloy has been investigated with an aim to compare with that of the amorphous $Al_{87}Ni_3Y_{10}$ alloy. The oxidation at 873 K occurs as follows: (1) growth of an amorphous aluminum-yttrium oxide layer (~10 nm) after heating up to 873 K; and (2) formation of $YAlO_3$ crystalline oxide (~220 nm) after annealing for 30 hours at 873 K. Such an overall oxidation step indicates that the oxidation behavior in the crystallized $Al_{87}Ni_3Y_{10}$ alloy occurs in the same way as in the amorphous $Al_{87}Ni_3Y_{10}$ alloy. The simultaneous presence of aluminum and yttrium in the oxide layer significantly enhances the thermal stability of the amorphous structure in the oxide phase. Since the structure of aluminum-yttrium oxide is dense due to the large difference in ionic radius between aluminum and yttrium ions, the diffusion of oxygen ion through the amorphous oxide layer is limited thus stabilizing the amorphous structure of the oxide phase.

• 말소리와 음성과학
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• 제10권2호
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• pp.69-76
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• 2018

The elderly are at increased risk of developing dysphagia due to aging and illnesses. The aim of the current study was to analyze, via an acoustic study, the change in the voice quality of normal elderly people after a 3oz water-swallow test. Subjects included a group of 60 normal elderly people (age: $mean{\pm}SD=76.9{\pm}6.66$) and 60 healthy young adults (age: $mean{\pm}SD=25.1{\pm}2.36$). Every participant produced a five-second /a/ phonation pre- and post-swallowing, and the fractioned two-second sections were analyzed using the MDVP (multi dimensional voice program) analysis. The elderly group demonstrated a post-swallowing increase in the following related acoustic parameters: fundamental frequency, fundamental frequency variation, amplitude-variation, and noise in both two-second sections. However, the younger group showed an increase only in frequency related acoustic parameters (i.e., STD ) in the first two-second section. The significant changes in values in the post-swallowing parameters might indicate temporary irregularities in pitch and amplitude along with higher amounts of noise in the voice. The results could be attributed to water residues in the vocal fold and vocal tract, as well as a deterioration of the motor and sensory functions caused by anatomical and physiological changes that result from aging.

• 한국생활과학회지
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• 제20권5호
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• pp.993-1008
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• 2011

An increase in interests in consumers' social responsibilities, or ethical spending, starts from a recognition that the consumption of an individual does not stop with the individual, but also affects overall society. The recognition of consumers' social responsibilities leads to demands for corporate social responsibility. Therefore, this study analyzed how social responsibility recognition affects consumers' needs for corporate social responsibility using college students. All data was analyzed with the SPSS Windows 18.0 program in terms of frequency, Crobach's ${\alpha}$, factor analyses, paired t-test, one-way ANOVA, and multiple regression. The results are as following: first, the recognition level of consumers' social responsibilities in college students was at an average level and the consumer's needs for corporate social responsibility were higher than usual. Second, the grade level, military experience, and economic status of the college students changed their views on consumers' needs for corporate social responsibility. Groups with higher consumers' social responsibilities had higher consumer demands for corporate social responsibility. Through this, we can see that consumers' social responsibilities affects the consumer's needs for corporate social responsibility.

• 한국주거학회논문집
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• 제24권3호
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• pp.27-35
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• 2013

The purpose of this study is to develop an evaluation system for integrative comfort values of Hanok residence. For this study, a mock-up located in Yongin, Gyeonggi province built by an ongoing governmental research project has been chosen. Then, SSN (Smart Sensor Network) has been utilized for monitoring quantitative factors in the environment and detailed face-to-face surveys have been performed for analyzing qualitative comfort indexes from residents in the experimental settings. Then, this study employs a combined evaluation system using AHP (Analytic Hierarchy Process) established for estimating overall DIC (Degree of Integrative Comfort) of the Hanok residence. As a result, the evaluation system could verify the total comfort indexes of Hanok residence and suggest converged methodologies for establishing value assessment system for traditional residential facilities. The method of DIC suggested in this paper would be examined with current residents in a built mock-up to see its applicability as a comprehensive evaluation model, and it is expected that collected year-round comfort data from the facility would provide more practical information towards future strategies for the Hanok residence.