• Title/Summary/Keyword: Ameliorating

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Leverage Strategy to National R&D Investment in Korea: A System Dynamics Approach (국가 연구개발 투자시스템의 레버리지 전략: 시스템 다이내믹스 접근)

  • Park, Hun-Joon;Oh, Se-Hong;Kim, Sang-Jun
    • Korean System Dynamics Review
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    • v.5 no.2
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    • pp.33-66
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    • 2004
  • This study is an exploratory investigation on how national R&D investments decisions are made in Korea. For developing system dynamic model, we are interested in locating three structural dilemma, occurring with the Korean NIS. In so doing, we intend to devise the ways of ameliorating problems within the NIS investment decision-making process by providing policy implications. We identify delays and side effects during transition periods between different stages of technology innovation by perceiving the switching pattern dynamically, in which form of technologies shifts from one to another stage like paradigm shift, when the R&D investment reaches a certain stock. It is also suggested that the development of strategies is necessary in order to enhance efficiency of technological development process.

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Effects of Metformin and Rosiglitazone in Overweight or Obese Women with Polycystic Ovarian Syndrome (과체중 및 비만 다낭성 난소 증후군 환자에서의 Metformin과 Rosiglitazone의 효용성)

  • Bai, Kwang Bum
    • Clinical and Experimental Reproductive Medicine
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    • v.32 no.4
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    • pp.347-352
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    • 2005
  • Objective: The purpose of this study was to evaluate and compare the effects of metformin and rosiglitazone in overweight or obese women with polycystic ovarian syndrome. Methods: Twenty Six overweight or obese patients with polycystic ovarian syndrome were randomly treated with either metformin (500 mg three times daily, n=13) or rosiglitazone (4 mg once daily, n=13) for 6 months. Hormonal studies were performed before and after treatment. Insulin resistances were calculated by computerized HOMA 2 Calculator v2.2. Results: Testosterone decreased while SHBG increased after 6 months treatment in both metformin and rosiglitazone treatment groups. Fasting glucose decreased after metformin or rosiglitazone treatment. HOMA insulin resistance improved after treatment with either drug. There was no differences in hormonal changes and insulin resistance between 2 treatment groups. Conclusions: This study shows that metformin and rosiglitazone are effective in improving insulin sensitivity and ameliorating hyperandrogenism in overweight/obese polycystic ovarian syndrome women.

Heat-processed ginseng saponin ameliorates the adenine-induced renal failure in rats

  • Kim, Eun Jin;Oh, Hyun-A;Choi, Hyuck Jai;Park, Jeong Hill;Kim, Dong-Hyun;Kim, Nam Jae
    • Journal of Ginseng Research
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    • v.37 no.1
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    • pp.87-93
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    • 2013
  • To evaluate the effect of the saponin of heat-processed ginseng (Sun ginseng, SG), we investigated the protective effect of SG total saponin fraction against adenine-induced chronic renal failure in rats. SG saponin significantly decreased the levels of urea nitrogen and creatinine in the serum, but increased the urinary excretion of urea nitrogen and creatinine, indicating an improvement of renal function. SG saponin also inhibited adenine-induced kidney hypertrophy and edema. SG saponin reduced serum glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, and lactate dehydrogenase activities increased by adenine. Based on these findings, the ameliorating effect of SG on chronic renal failure may result from its saponin.

Effects of acupuncture on bone mineral density in ovariectomized rats (자극(刺鍼)이 난소(卵巢)를 절제(切除)한 흰쥐의 골밀도(骨密度)에 미치는 영향(影響))

  • Kim Mi-Ryeo;Yang Chae-Ha
    • Journal of Acupuncture Research
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    • v.15 no.2
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    • pp.279-285
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    • 1998
  • Effects of acupuncture at Sanyinjiao(SP6) and Yanglingquan(GB34) on bone mineral sensity(BMD) was investigated in ovariectomized(OVX) rats. BMD of OVX rats was measured left femur and tibia 2 and 4 weeks after acupuncture stimulation, respectively. Compared with sham-operated rats, a significant decrease in spine, pelvic and left femoral and tibial BMD was observed 2 and 4 weeks after OVX, respectively. In contrast, a significant increase of spinal, pelvic and left femoral and tibial BMD was elicited 2 and/or 4 weeks after acupuncture stimulation, respectively. These results show the possibility that acupuncture can play a role of ameliorating osteoporosis by elevating serum levels of female hormones related with bone metabolism.

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Cause and Prevention of Falling in the Elderly (노인낙상의 원인과 예방)

  • Chung, Nak-Su;Choi, Kyu-Hwan
    • Physical Therapy Korea
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    • v.8 no.3
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    • pp.107-117
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    • 2001
  • Falls are the most serious health problems in elderly population. They are a major cause of premature death, physical injury, immobility, psychosocial dysfunction, and nursing home placement. To reduce the alarming rate of falls and related excessive mortality and morbidity, efforts must be made to detect persons at risk of falling and to prevent or reduce the frequency of falls. To facilitate such approaches, it is essential to find the cause of falling (and under what conditions) of the elderly and the factors that are associated with risk of falling. This study was aimed at designing interventions that minimize risk of falling by ameliorating contributing factors while maintaining or improving patient's mobility.

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A dynamic approach to manufacturing improvement from learning and decision-theoretic perspectives

  • Kim, Bowon
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 1996.10a
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    • pp.49-52
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    • 1996
  • In this article, we develop a 'dynamic' approach to manufacturing improvement, based on perspectives of manufacturing learning and decision theory. First, we present an alternative definition of production system consistent with a decision-theoretic perspective: the system consists of structural, infra-structural, and decision making constructs. A primary proposition is that learning capability possessed by a manufacturing system be prerequisite for the system to improve its manufacturing performance through optimal controlling of the three constructs. To support the proposition, we elaborate on a mathematical representation of "learning" as defined in an applied setting. We show how the learning capability acts as an integrating force ameliorating the trade-off between two key manufacturing capabilities, i.e., process controllability and process flexibility.exibility.

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A Study on the Location Characteristics and Present Distribution of Facilities in the Community (지역시설의 입지특성 및 분포현황에 관한 연구)

  • Jang, Taek-ju
    • Journal of the Korean Institute of Rural Architecture
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    • v.9 no.3
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    • pp.1-10
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    • 2007
  • This study aims to discuss the location characteristics and present distribution of facilities in the rural community. The purpose of this study is to suggest the basic data of the planning of facilities corresponding to the living sphere in community. The circumstances, location and distribution of the rural area facilities was analyzed through field investigation and interview. lt is necessary for ameliorating the income of inhabitants and the status of living environment to make a general local plan in developing rural area. That will be a solution to tackle the decreasement of population in the rural area. The survey's result is observed different by the feature of rural area, adjacence with near rural center, scale of rural center. So a standard of the various facility's arrangement plan must be established, and it must be enlarged in rural area.

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A Clinical Case of Dermatomyositis Complicated by Henoch-Schonlein Purpura (피부근염에 이환되었던 환아의 Henoch-Schonlein 자반증 증례 1례)

  • 홍상훈;김성환
    • The Journal of Korean Medicine
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    • v.23 no.2
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    • pp.225-230
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    • 2002
  • Dermatomyositis is an inflammatory cutaneo-muscular disease of unknown etiology, characterized by symmetrical proximal muscle weakness and typical dermatologic manifestation. Henoch-Schonlein purpura is most common in children. In Korea, dermatomyositis or Henoch-Schonlein purpura associated with herbal medicine has not been reported. The subject patient is a seven year-old girl diagnosed with dermatomyositis in August 1999 and Henoch-Schonlein purpura in January, July 2001. There were symptoms of dermatomyositis such as headache, arthralgia, eruption, itching and abdominal pain. I think the herb-prescription composed or Radix astragali (Huangqi), Herba agrimoniae (Xianhecao), Fructus jujubae (Dazao) had an ameliorating effect on Henoch-Schonlein purpura by decreasing these symptoms.

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Utilization of Masking Techniques to Ameliorate Agricultural Odorants

  • Yoon, Young-Mo;Schilling, Mark W.;Bazemore, Russell
    • Food Science and Biotechnology
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    • v.14 no.5
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    • pp.689-693
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    • 2005
  • Different masking materials were evaluated for their ability to ameliorate odor of model poultry manure solution by assessing their effects on sensory pleasantness and odor intensity. Results indicated extracts from Eastern red cedar leaves, Loblolly pine needles', and commercial masking agents such as pine extract and odor neutralizer were effective (p<0.05) for masking odor of model poultry manure solution by increasing (p<0.05) pleasantness (82 and 86% increases in pleasantness using red cedar and pine needle extracts, respectively) and decreasing (p<0.05) odor intensity (odor intensity reduction by 66 and 76% using red cedar pine needle extract). The most odor-active compound in Loblolly pine needle extract was ${\alpha}$-terpineol (1,573.8 ug/g) which is responsible for aroma of pine trees (piney) and effective for ameliorating agricultural odors.

Implementation and Evaluation of a Course: A Case Study of PBL Class at Pusan National University (PBL 기반 <토의> 수업 모형의 구현과 평가: 부산대학교 수업개발 사례를 중심으로)

  • Hwang, Soon-Hee
    • Journal of Engineering Education Research
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    • v.14 no.4
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    • pp.88-96
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    • 2011
  • This paper aims to develop the learning contents of PBL based program and analyze the result of evaluation questionnaire to examine the students' thoughts concerning the effectiveness of PBL course and their satisfaction. 'Discussion' is one of the representative communicative types, especially requesting both communication competence and teamwork among team members. This study was conducted with 218 junior and senior students taking lectures of ${\ll}$Presentation and Debate Skills${\gg}$ in the college of engineering at Pusan National University. According to the evaluation result, students experienced various effects of PBL such as (1) self-directed learning, (2) cooperative learning, (3) problem solving skills, etc. Students pointed out also as merits of PBL course, (1) knowledge acquisition and information sharing among students, (2) improvement of communicative competence, (3) amelioration of teamwork, (4) progress of the problem solving skills. However, there have been several difficulties and problems during PBL process, implications for ameliorating PBL based were discussed and suggested in detail.