• Title/Summary/Keyword: Amanita muscaria

Search Result 3, Processing Time 0.021 seconds

The Toxicological Pathologic Study of Amanita muscaria in Sprague-Dawley Rat (Amanita muscaria 경구투여 시 Sprague-Dawley Rat에서의 독성병리 연구)

  • Kim, Jin;Kim, Hyeong-Jin;Kim, So-Jung;Kim, Byeong-Soo;Kim, Sang-Ki;Park, Byung-Kwon;Park, Young-Seok;Cho, Sung-Dae;Jung, Ji-Won;Nam, Jeong-Seok;Choi, Chang-Sun;Lee, Seung-Ho;Jung, Ji-Youn
    • Journal of Life Science
    • /
    • v.19 no.8
    • /
    • pp.1152-1158
    • /
    • 2009
  • For the toxicological pathologic study of amanita muscaria, we have investigated single and repeated dose toxicity in Sprague-Dawley (SD) rats. Single dose toxicity study was identified as catalepsy, incline and tail pinch methods (control 0 mg/kg, low 3.3 mg/kg, middle 16.5 mg/kg, high 33.0 mg/kg). Repeated dose toxicity study was carried out in blood tests, serum tests and histopathological methods. Neurotoxicity - muscle paralysis, and convulsion and loss of movement - was observed at 33.0 mg/kg group in the single dose toxicity study. Dysfunction of liver and kidney were shown in the repeated oral administration of the amanita muscaria at 3${\sim}$4 weeks. Serum chemistry results revealed a marked increase of LDH [Lactate Dehydrogenase (3181.5 IU/L; normal 230-460 IU/l)], ALT [Alanine transaminase (124.0 IU/l; normal <40 IU/l)] but the kidney was normal. Histopathological results show interstitial edema and tubular epithelial necrosis in the kidney. These results suggest that amanita muscaria has a neurotoxic effect and causes dysfunction of liver and kidney in the SD rat.

The Fungal Resources of Mt. Paekdu Areas (백두산 일대의 균류 자원)

  • Cho, Duck-Hyun
    • Korean Journal of Plant Resources
    • /
    • v.23 no.1
    • /
    • pp.115-121
    • /
    • 2010
  • Many fungi were collected in Mt. Paekdu areas from May, 2002 to September, 2008 and were identified. As the resulting, the following species were unrecorded to Korea ; Clitocybe alnetorum, C. catinus, C. metachroa, C. odora var. alba, C. phyllophilla, Amanita muscaria var. formosa, A. pantherina var. lutea, Coprinus semitalis, Agrocybe dura, Inocybe grammata, Cortinarius epipolius and C. nemorensis. They were added list of Korean fungal resources.

The Mycoflora of Higher Fungi in Mt. Paekdu and Adjacent Areas (I) (백두산(白頭山)의 고등균류상(高等菌類相)에 관(關)한 연구(硏究)(I))

  • Park, Seong-Sick;Cho, Duck-Hyun
    • The Korean Journal of Mycology
    • /
    • v.20 no.1
    • /
    • pp.11-28
    • /
    • 1992
  • Some 420 species of higher fungi were collected from the Mt. Paekdu, Songwha river and their adjacent areas from 28th July to 12th of August, 1991 and identified to 2 subdivisions, 4 classes, 2 subclasses, 12 orders, 51 families, 141 genera and 336 species. The dominant species were Clitocybe gibba, C. clavipes, ystoderma amianthinum, Hygrocybe flavescens, H. miniata, Russula cyanoxantha, R. metica, Lactarius lignyotus, L. torminosus and Phellinus igniarius. The species found in Mt. Paekdu were newly described; Amanita muscaria var. regaris, Volvariella species var. speciosa, Cortinarius alboviolaceus, C. violaceus, Inocybe geolilacina, I. hirtella var. hirtella, Boletinus paluster, Crepidotus badiofloccosus, Lactarius circellatus var. circellatus, L. controversus and L. cilicioides.

  • PDF