• Title/Summary/Keyword: Aluminum toxicity

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Biochemical Study on the Effects of the Omija(Schizandra chinensis Baillon) Extracts in Rat Kidney Toxicity Induced by Aluminum (오미자 추출액이 알루미늄 투여에 의한 흰쥐의 알루미늄 축적률에 미치는 영향)

  • Jung, Young-Hee;Han, Sung-Hee
    • The Korean Journal of Food And Nutrition
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    • v.24 no.1
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    • pp.28-36
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    • 2011
  • To investigate the protective effect of omija(Schizandra chinensis Baillon) tea extracts against the aluminum toxicity, Sprague-Dawley rats($100{\pm}10\;g$) were divided into 6 groups consisting of a control group, a 3% Schizandra chinensis Baillon tea plus extract group, a 1,000 and 2,000 ppm aluminum group, and a 1,000 and 2,000 ppm aluminum plus 3% Schizandra chinensis Baillon tea plus extract group. The rats administered aluminum were given 1,000 and 2,000 ppm of $Al_2(SO_4)_3$ dissolved in distilled water. The aluminum content in tissues from rats administered aluminum was lower than in the tissues of rats of administered aluminum plus 3% Schizandra chinensis Baillon tea in the water extract. Aspartate aminotransferase (AST) and alanine aminotransferase(ALT) levels were increased in the aluminum group and lower in the group receiving a 3% extract of Schizandra chinensis Baillon tea. Lactate dehydrogenase(LDHase) was lower in the group receiving a 3% extract of Schizandra chinensis Baillon tea plus aluminum than in the aluminum group. Cholinesterase(ChEase) was higher in the 3% Schizandra chinensis Baillon tea-aluminum group than in the aluminum group. Plasma levels of renin were increased in the aluminum group, compared to the group receiving 3% Schizandra chinensis Baillon tea plus aluminum. Plasma levels of aldosterone were increased in the aluminum group compared with the 3% Schizandra chinensis Baillon tea plus aluminum group. These results suggest that the group receiving Schizandra chinensis Baillon tea in water extract had a lowered level of aluminum accumulation, and it is believed that the Schizandra chinensis Baillon tea plus water had some protective effects against aluminum toxicity when administered in rats, but the mechanism of these effects remains obscure.

Application of Toxicity Identification Evaluation Procedures for Toxic Effluents from the Aluminum Rolling Industry (알루미늄 가공 공장 배출 방류수의 독성 원인물질 탐색)

  • Ra, Jin-Sung;Lee, Jiho;Kim, Ki-Tae
    • Journal of Environmental Health Sciences
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    • v.41 no.5
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    • pp.305-313
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    • 2015
  • Objectives: The objective of this study is to identify toxicants causing acute toxicity in effluents from the aluminum rolling industry that violate the discharge limits in Korea. Methods: Whole effluent toxicity tests (WET) were conducted on effluent discharged from the aluminum rolling industry following the US EPA WET test methods. We collected effluent samples three times and evaluated acute toxicity by using Daphnia magna. We employed toxicity identification evaluation (TIE) procedures to identify toxicants causing toxicity in the effluent. Results: No specific chemical groups were identified in the seven different manipulations applied to the of wastewater effluent samples showing 1.3 toxic units (TU) according to the TIE phase I procedures. Water quality parameters for water hardness, electric conductivity and heavy metals (Mn) were 4,322 mg/l as $CaCO_3$, 11.39 mS/cm, and $5,551{\mu}g/l$, respectively. Considering water hardness and reference toxicity, high concentrations of Mn can be disqualified from the causative toxicants. Consequently, high ionic concentrations of $Na^+$(1,648 mg/l), $Ca^{2+}$(1,048 mg/l), $Mg^{2+}$(1,428 mg/l) and $SO_4{^{2-}}$(7,472 mg/l) were identified to be causative toxicants. Water hardness and electric conductivity exceed the $EC_{50}$ value obtained by biological toxicity tests using Daphnia magna. Conclusion: According to TIE procedures, high salt concentration is determined to be a major toxicant in the effluent of agro-industrial wastewater treatment plants receiving wastewater from the aluminum rolling industry.

Toxic Effects of Aluminium on Freshwater Animals: Review (알루미늄이 수생동물에 미치는 독성에 관한 소고)

  • Park, Chan Jin;Kim, Dae Han;Han, Sang Ho;Gye, Myung Chan
    • Korean Journal of Environmental Biology
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    • v.32 no.4
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    • pp.271-285
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    • 2014
  • Aluminum flows into the river from the abandoned mine leachate, industrial wastewater, and sewage and is responsible for acute toxicity in aquatic organisms. Recently, the number of reports have indicated the increased toxicity in a variety of aquatic organisms' due to the aluminum toxicity. In this study, we reviewed the toxicity of aluminum on aquatic invertebrates, fishes and amphibians and suggested the guideline for management of aluminum residues in aquatic environment and strategies for aluminum toxicity evaluation. In aquatic animals aluminum complexes evoke gill dysfunction primarily, the cytotoxicity, genotoxicity, oxidative stress, disruption of endocrine function, reproductive success, metabolism and homeostasis. Notably, at environmentally relevant concentration, aluminum complex can alter the hormone levels in fish in acidic condition. Further, since the solubility of aluminum is higher in the acidic and basic conditions, thus it is likely that the toxic effects of aluminum may not only occur in acidic water near the abandoned mines but also in lakes and rivers, where pH is raised by algal bloom.

Effects of Aluminum Solution Treatment on the Growth of Forsythia koreana Cuttings (알루미늄용액 처리가 개나리삽수의 생장에 미치는 영향)

  • 김갑태
    • Korean Journal of Environment and Ecology
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    • v.6 no.1
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    • pp.9-11
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    • 1992
  • To examine aluminum toxicity on woody plants, Forsythia koreana cuttings were grown in the aluminum solution and ground water(pH 6.75). Aluminum solution were prepared 1.0, 2.5 and 5.0mM aluminum potassium sulfate, dilulted with ground water. Shoot growth, leaf number, leaf injury and leaf chlorophyll content were measured and compared among the treatments. In all growth-related characters(shoot growth. leaf number, leaf injury and leaf chlorophyll content), differences among the treatments were highly significant. Forsythia koreana cuttings were severely stressed in aluminum solution more than 1.0mM concentration.

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How do Citrus Crops Cope with Aluminum Toxicity?

  • Arunakumara, K.K.I.U.;Walpola, Buddhi Charana;Yoon, Min-Ho
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.6
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    • pp.928-935
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    • 2012
  • World Agriculture faces daunting challenges in feeding the growing population today. Reduction in arable land extent due to numerous reasons threatens achievement of food and nutritional security. Under this back ground, agricultural use of acidic soils, which account for approximately 40 % of the world arable lands is of utmost important. However, due to aluminum (Al) toxicity and low available phosphorous (P) content, crop production in acidic soils is restricted. Citrus, in this context, gains worldwide recognition as a crop adapted to harsh environments. The present paper reviewed Al toxicity and possible toxicity alleviation tactics in citrus. As reported for many other crops, inhibition of root elongation, photosynthesis and growth is experienced in citrus also due to Al toxicity. Focusing at toxicity alleviation, interaction between boron (B) and Al as well as phosphorus and Al has been discussed intensively. Al toxicity in citrus could be alleviated by P through increasing immobilization of Al in roots and P level in shoots rather than through increasing organic acid secretion, which has been widely reported in other crops. Boron-induced changes in Al speciation and/or sub-cellular compartmentation has also been suggested in amelioration of root inhibition in citrus. Despite the species-dependent manner of response to Al toxicity, many commercially important citrus species can be grown successfully in acidic soils, provided toxicity alleviation Agro-biological tactics such as addition of phosphorous fertilizers are used properly.

Effects of Zinc and Aluminum Hot-dip Galvanized Sheet Steel on the Gill and Hepatopancreas of the Abalone Haliotis discus hannai (아연 및 알루미늄 용융도금 처리된 강판이 북방전복(Haliotis discus hannai)의 아가미와 간췌장에 미치는 영향)

  • Lee, Chi Hoon;Park, Jun Young;Lee, Young Don
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.50 no.4
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    • pp.388-395
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    • 2017
  • We investigated the toxicity of zinc and aluminum hot-dip galvanized sheet steel to abalone Haliotis discus hannai via changes in the gill and hepatopancreas using histological and transmission electron microscopy analysis. Experimental groups were composed of one control and four exposure conditions (direct or indirect exposure to zinc and aluminum hot-dip galvanized sheet steel). In the control group, aluminum exposure groups (direct and indirect), and indirect zinc exposure group, abalone mortality was not observed until the end of the experiment, and no histopathological changes were observed in the gill and hepatopancreas. However, the direct zinc exposure group exhibited 100% mortality. Ultrastructural analysis of the cytoplasm of ciliated and microvilli-bearing epithelial cells from gill filaments revealed electron-dense vesicles near the cell membrane and disruption of the nuclear membrane. We also observed swollen mitochondria and a loss of mitochondrial cristae. The hepatopancreas showed similar changes, and we detected highly electron-dense particles within the vesicles. These results suggest that abalone exposed directly to zinc hot-dip galvanized sheet steel experience acute toxicity, causing damage to cell organelles in the gill and hepatopancreas and, finally, inducing mortality.

Fenugreek seeds reduce aluminum toxicity associated with renal failure in rats

  • Belaid-Nouira, Yosra;Bakhta, Hayfa;Haouas, Zohra;Flehi-Slim, Imen;Cheikh, Hassen Ben
    • Nutrition Research and Practice
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    • v.7 no.6
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    • pp.466-474
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    • 2013
  • Despite the reports on safety concerns regarding the relationship between aluminum salts and neurological and bone disease, many countries continue to use aluminum as phosphate binders among patients with renal failure. In search for a diet supplement that could reduce aluminum toxicity related to renal failure, we carried out this prospective animal study in which the fenugreek seeds were assessed for their effects on rats nephrotoxicity induced by aluminum chloride ($AlCl_3$). Oral $AlCl_3$ administration during 5 months (500 mg/kg bw i.g for one month then 1600 ppm via drinking water) led to plasma biochemical changes, an inhibition of alkaline phosphatase (ALP), a decrease of total antioxidant status (TAS), and an induction of lipid peroxidation (LPO) in the blood and brain, in addition to kidney atrophy and morphological alterations at the level of Bowman's capsule, the glomerulus and different sorts of tubules, reminiscent of some known kidney disease. The treatment with the whole fenugreek seed powder (FSP) (5% in the diet) during the last 2 months showed its effectiveness in restoring normal plasma values of urea, creatinine, ALP and glucose, as well as re-increasing the TAS, inhibiting LPO and alleviating histopathological changes in the injured kidneys. This study highlights the induced nephrotoxicicity, as well as the related toxicity in the brain and bone, by chronic oral ingestion of the aluminum salts. However, the maintenance of a diet supplemented with fenugreek seeds could offer protection for the kidney, bone and brain, at the same time.

Effects of Aluminum Solution Treatment on Seed Germination and Seedling Growth of Three Tree Species (알루미늄용액 처리가 세 수종의 종자발아와 묘목생장에 미치는 영향)

  • 김갑태;추갑철;엄태원
    • Korean Journal of Environment and Ecology
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    • v.7 no.1
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    • pp.1-5
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    • 1993
  • To examine aluminum toxicity on woody plants, aluminum solution and ground water(pH 6.75) were treated on the seeded pot (48$\times$33$\times$9cm) of Pinus thunbergiana, Thuja orientalis and Ligustrum obtusifolium, filled with sand, three times per week, 5mm per time, from April 28, 1993 to June 16. Aluminum solution were prepared 1.0, 2.5 and 5.0mM aluminum potassium sulfate, dilulted with ground water. Growth-related characters(seedling number, seedling height, top, root and total dry weight) were measured and compared among species and treatments. The response of seedling growth-related characters to aluminum solution treatment differed among the species, and the most sensitive species is Ligustrum obtusifolium, and the most tolerant species is Pinus thunbergiana.

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Reduction of Aluminum Toxicity by Calcium and Magnesium in Pines (소나무속 식물에서 칼슘과 마그네슘에 의한 알루미늄 독성의 경감)

  • Ryu, Hoon;Joon-Ho Kim
    • The Korean Journal of Ecology
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    • v.19 no.3
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    • pp.193-199
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    • 1996
  • Alleviation of Al toxicity by Ca and Mg was studied with seedings of Pinus densiflora, P. rigida and P. thunbergii under the solution culture. The seedlings were cultivated in the enriched Can and Mg nutrient solution with 2, 000 ${\mu}M$ Al for three weeks. The hightest total root lengths of P. densiflora, P. rigida and P. thunbergii increased by 21, 33 and 133% in Ca enriched solution, and 23, 44 and 107% in Mg enriched solution, respectively. Ratios of lateral root to main root length increased significantly in Mg enriched solution, and redution of Al toxicity was more affected by enriched Mg than by enriched Ca. Al content in tissue was reduced by enriched Ca and Mg.

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Effects of Aluminum Solution Treatment on the Growth of Forsythia koreana and Platanus occidentalis Cuttings(2) (알루미늄용액 처리가 개나리와 플라타너스삽수의 생장에 미치는 영향(2))

  • 김갑태;추갑철;진운학
    • Korean Journal of Environment and Ecology
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    • v.7 no.1
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    • pp.6-9
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    • 1993
  • To examine aluminum toxicity on woody plants, Forsythia koreans and Platanus occidentalis cuttings were grown in the pot(48$\times$33$\times$9cm) filled with sand, and treated aluminum solution and ground water (pH 6.75) 3times per week from April 28, 1993 to June 16. Aluminum solution were prepared 1.0, 2.5 and 5.0mM aluminum potassium sulfate, dilulted with ground water. Growth-related characters (Shoot growth, leaf number and leaf chlorophyll content ) and root growth were measured and compared among the treatments. In all growth-related characters(Shoot growth, leaf number and leaf chlorophyll content), differences among the treatments were highly significant. In root growth, differences among the treatments were highly significant for Forsythia koreana cuttings, but not for Platanus occidentalis cuttings.

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