• Journal of the Korean housing association
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• 제22권3호
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• pp.25-33
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• 2011

Recently, concerns about conserving proper size of urban green spaces and accessibility are increasing, regarding it as a solution to diverse urban environmental problems including pollution, ecosystem deterioration, urban climate change. Artificial ground greening such as green roofs is regarded as the only alternative that can conserve green spaces which are impossible to be secured on the ground. However, green roofs are not popularized yet and levels are very low in provincial cities despite of related technology development and support systems of related agencies. Based on the background, this study tries to present a theoretical basis of methods for green roofs, conducting green roof simulations Finally, it aims to offer base data which help establish policy direction for activation of green roof technology. As a result of a simulation for verifying temperature reduction effect, it was possible to affirm effect of a plot that green roofs applied. Especially, it was revealed that a green roof method using ground covers such as mixed planting was the most effective way to reduce temperature. Based on precise analysis of the users, actual study for activation of green roofs should be developed in the future, by presenting a standard model for experiments and obtaining information about examples of green roofs on private houses.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• 제69권
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• pp.617-632
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• 2016

After contracting of Korea-China FTA, we have expected the trade volume has mutually been increasing a lot. If we are using this contract, we would make an activation of Korea economy. Especially, Korea youngman has been caught a big chance to make a business in Korea & China. For example, Xian, which is one of center of silk road, has become big strategy area. As we need to focus on this area, we will be expected to indirect influences of consumer's industries like cosmetic, fishery products, food service, eco-friendly items. Recently, the youngman starting up a business has become a trend of kinds of alternative new job. Then, we have to provide practical solution for young man. One of this solution is 'starting up a business'. In this study, I empirically investigated the relation between Korea-China FTA and the youth starting up a business. So, I believe that this study can light up on the direction of effective starting up for making & success a business in China.

• Journal of Photoscience
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• 제9권2호
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• pp.475-478
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• 2002

In zoological research, penetration of light has been reported of the frontal bones of fish, birds, and reptiles, suggesting the existence of physiologically direct photic routes to frontal lobes and/or deep parts of the brain. We studied the influences of frontal exposure to photodiode light on frontal alpha wave and peripheral NK cells. Repetitive exposure of the subject's forehead to a red light diode (660nm) significantly increased the effective amplitude of the frontal alpha waves (using a mean frequency with a range of +1.0 Hz), peripheral NK activity, and the level of CD57-CD16+. Frontal alpha wave activity and the level of CD57-CD16+ increased, suggesting the possibility of a non-invasive procedure for the activation of the frontal lobe and the increase of NK cells. This light is considered to penetrate the frontal bones of humans directly, and to act on the frontal lobe and/or other immunological regulatory centers in the brain, resulting in some neuro-immunological changes.

• The Korean Journal of Physiology and Pharmacology
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• 제16권2호
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• pp.139-144
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• 2012

It has been reported that activation of metabotropic glutamate receptor 1 (mGluR1) can mediate endocannabinoid-induced short-term depression of synaptic transmission in cerebellar parallel fiber (PF)-Purkinje cell (PC) synapse. mGluR1 has signaling pathways involved in intracellular calcium increase which may contribute to endocannabinoid release. Two major mGluR1-evoked calcium signaling pathways are known: (1) slow-kinetic inward current carried by transient receptor potential canonical (TRPC) channel which is permeable to $Ca^{2+}$; (2) $IP_3$-induced calcium release from intracellular calcium store. However, it is unclear how much each calcium source contributes to endocannabinoid signaling. Here, we investigated whether calcium influx through mGluR1-evoked TRPC channel contributes to endocannabinoid signaling in cerebellar Purkinje cells. At first, we applied SKF96365 to inhibit TRPC, which blocked endocannabinoid-induced short-term depression completely. However, an alternative TRP channel inhibitor, BTP2 did not affect endocannabinoid-induced short-term depression although it blocked mGluR1-evoked TRPC currents. Endocannabinoid signaling occurred normally even though the TRPC current was mostly blocked by BTP2. Our data imply that TRPC current does not play an important role in endocannabinoid signaling. We also suggest precaution in applying SKF96365 to inhibit TRP channels and propose BTP2 as an alternative TRPC inhibitor.

• Korean Journal of Pharmacognosy
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• 제44권2호
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• pp.110-117
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• 2013

Cirsium japonicum (CJ) leaf (L) alcoholic extracts were investigated for analysis their active components (flavonoids and flavanolignans; silymarins) and inhibitory effect on transforming growth factor (TGF)-${\beta}$ induced hepatic stellate cells (HSCs, LX-2 cells) activation. The CJ root (R) extracts were also analyzed and compared with leaf extracts. Total flavonoid and polyphenol contents of the leaf extracts showed higher than those of the root extracts. The content of each flavonoid compound, which was analyzed by HPLC, in CJ-L extracts was also higher than in CJ-R extracts. The results of flavanolignans content in CJ-L and CJ-R extracts were consistent in flavonoid and polyphenol. We studied inhibitory effect of two extracts against TGF-${\beta}1$ induced HSCs activation. The CJ-L extracts significantly suppressed overexpression of profibrogenic factor, ${\alpha}$-smooth muscle actin and collagen-${\alpha}1$(I). The CJ-R extract also showed inhibitory effect on TGF-${\beta}1$ induced HSCs activation, but the efficacy was lower than in CJ-L extract. These results suggest that CJ-L may contribute to the fibrotic liver treatment.

• Journal of the Korea Organic Resources Recycling Association
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• 제25권3호
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• pp.63-71
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• 2017

In this study, washing parameters such as washing time, agitation velocity, and cycles were optimized for high surface area of the activated carbon (AC) by KOH activation. Even though AC with high surface area showed at higher washing efficiency, over 90% on washing efficiency was regulated by the intra-particle diffusion due to high tortuosity of the pore structures on AC. In addition, we can obtain $K_2CO_3$ through the evaporation from the wastewater and use it for chemical activation of AC. The AC with $K_2CO_3$ activation has specific surface area values of $2,219m^2/g$ equally that of KOH activation. Considering that $K_2CO_3$ is an effective alternative as a KOH, our results demonstrated that the process by recycling wastewater on AC production could be applicable for near-zero wastes.

• Journal of the Korean Institute of Rural Architecture
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• 제8권2호
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• pp.11-18
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• 2006

Ecomuseums come into close relationship with resident and community. Progress of heritage concept brings on the change of valuation standard in heritage, that life style of residents become most important element of cultural heritage. The change of display method has caused the generation of various experience programs in ecomuseum which are display and education based on participation of visitors and residents. Ecomuseums in Europe during progress have conceptual peculiarities by themes to keep the cultural identity and protect folk culture in regional community. 'Europe Ecomuseum Network' seriously affected by social change and development is new alternative to promote regional identity and cultural exchange among Europe countries. People participation with all residents is decisive factor to promote identity and attachment in native place, as well as collaboration with residents, experts, administrators and NGO is one factor for sustainable development and the realization of ecomuseum, activation of regional economy, and also is the root of efforts to protect and activate regional community.

• Ocean policy research
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• 제33권2호
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• pp.123-145
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• 2018

Maritime tourism destinations need to improve image as well as enhance competitiveness through development of new marine tourism attraction due to the decrease of the number of passengers. The maritime city is trying to combine dynamic marine leisure activities as an alternative. For this purpose, it is possible to realize clear marine tourism activation policy and improve the identity of local community through the accurate analysis of the interest of the stakeholder groups of local residents in Songjeong beach in Busan. In this study, we first analyzed the language network based on the expression language related to the conflict between the stakeholders of Songjeong beach. Second, we analyzed the individual characteristics of the structure of conflict frames of stakeholders and suggested solutions by comparing the differences and similarities between perception frames of conflict parties. Third, we distinguish and compare differences of perception among the conflict parties through the detailed frame type. Based on the relationship structure between the detailed frame types of the conflict parties, we suggested an alternative for conflict resolution by restructuring the conflicts and negative perceptions among the stakeholders.

• Preventive Nutrition and Food Science
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• 제1권1호
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• pp.41-45
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• 1996

This study was conducted to develop the fermentation kinetic model for the prediction of acidity and pH changes in Kimchi as a function of fermentation temperatures. The fitness of the model was evaluated using traditional two-step method and an alternative non-linear regression method. The changes in acidity and pH during fermentation followed the pattern of the first order reaction of a two-step method. As the fermentation temperature increased from 4$^{\circ}C$ to 28, the reaction rates of acidity and pH were increased 8.4 and 7.6 times, respectively. The activation energies of acidity and pH were 16.125 and 16.003kcal/mole. The average activation energies of acidity and pH using a non-linear method were 16.006 by the first order and 15.813 kcal/mole by the zero order, respectively. The non-linear procedure had better fitting 개 experimental data of the acidity and pH than two-step method. The shelf-lives based on the time to reach the 1.0% of acidity were 33.1day at 4$^{\circ}C$ and 2.8 day 28$^{\circ}C$.

• Korean Journal of Fisheries and Aquatic Sciences
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• 제48권4호
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• pp.439-446
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• 2015

Inflammation is a protective response to infection or injury. However, prolonged inflammation can contribute to the pathogenesis of many diseases, such as cancer, diabetes, arthritis, atherosclerosis, and Alzheimer's disease. Recent studies have shown that activated macrophages, inflammatory effector cells, can react to tissue insults in a polarized manner, in which their phenotypes are polarized into two major subtypes, categorized as M1 or M2. Classical M1 activation involves the production of pro-inflammatory cytokines, such as interleukin (IL)-6 and tumor necrosis factor (TNF)-${\alpha}$, and free radicals, while M2 or alternative activation is an anti-inflammatory phenotype involved in homeostatic processes, such as wound healing, debris scavenging, and the dampening of inflammation via the production of very low levels of pro-inflammatory cytokines and high levels of anti-inflammatory mediators, including IL-10. As part of our ongoing effort to isolate anti-inflammatory compounds from seaweeds, we investigated the effects of phlorotannins isolated from the brown alga Ecklonia stolonifera on macrophage polarization. Mouse peritoneal macrophages were treated with various concentrations of the extracts, and real-time RT-PCR analyses were performed to examine the expression of polarization markers: IL-$1{\beta}$, IL-6, and TNF-${\alpha}$ for M1 and arginase-1, peroxisome proliferator-activated receptor (PPAR)-${\gamma}$, found inflammatory zone-1 (Fizz-1), chitinase 3-like 3 (Ym1), and$Kr{\ddot{u}}ppel$-like factor 4 (Klf-4) for M2. The pretreatment of cells with eckol, dieckol, and phlorofucofuroeckol-A (PFF-A), isolated from the ethyl acetate fraction of E. stolonifera ethanolic extract, potentiated the anti-inflammatory M2 phenotype of the macrophages. These results indicate that phlorotannins derived from E. stolonifera can be used to enrich macrophages with markers of the M2 anti-inflammatory state.