• Journal of the Society of Cosmetic Scientists of Korea
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• v.28 no.3
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• pp.171-184
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• 2002

The present study was undertaken to develop the in vitro sunprotection factor(SPF) measurement method having good correlation with in vivo method. As in vitro method, 8% homomentyl salicylate, P3 reference standard and sunscreens on market were measured using SPF 290 analyzer and were compared the SPF with labed value. In vitro SPF of 8% HMS and P3 reference standard were 4.59 $\pm$ 0.12 and 14.94 $\pm$ 0.83. There are good correlation, correlation factor were 0.9506 and 0.9769 respectively, between the in vitro and in vivo SPF for the sunscreen creams and lotions examined. Correlation factors of makeup base & liquid goundation, lotion labled with “shake before use”, compact powder were 0.8812, 0.8632 and 0.5984. The best sample applied method of compact powder was 1:0.8 mixture with cream base. These results suggest that the in vitro test method could be used as an alternative method for SPF.

• Journal of Food Hygiene and Safety
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• v.27 no.1
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• pp.37-41
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• 2012

The current standard for testing tetrodotoxin (TTX) in foodstuffs is the mouse bioassay (MBA) in Korea as in many other countries. However, this test suffers from potential ethical concerns over the use of live animals. In addition, the mouse bioassay does not test for a specific toxin thus a sample resulting in mouse incapacitation would need further confirmatory testing to determine the exact source toxin (e.g., TTX, STX, brevotoxin, etc.). Furthermore, though the time of death is proportional to toxicity in this assay, the dynamic range for this proportional relationship is small thus many samples must be diluted and new mice be injected to yield a result that falls within the quantitative dynamic range. Therefore, in recent years, there have been many efforts in this field to develop alternative assays. High performance liquid chromatography (HPLC) coupled with mass spectrometry (MS) has been emerged as one of the most promising options. A LC-MS-MS method involves solid-phase extraction (SPE) and followed by analysis using an electrospray in the positive ionization mode and multiple reactions monitoring (MRM). To adopt LC-MS-MS method as alternative standard for testing TTX, we performed a validation study for the quantification of TTX in puffer fish. This LC-MS-MS method showed good sensitivity as limits of detection (LOD) of $0.03{\sim}0.08{\mu}g/g$ and limits of quantification (LOQ) of $0.10{\sim}0.25{\mu}g/g$. The linearity ($r^2$) of tetrodotoxin were 0.9986~0.9997, the recovery were 80.9~103.0% and the relative standard deviations (RSD) were 4.3~13.0%. The correlation coefficient between the mouse bioassay and LC/MS/MS method was higher than 0.95.

• Journal of Korean Biological Nursing Science
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• v.11 no.1
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• pp.51-58
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• 2009

Purpose: It is to verify learning effect of the instructional media on anatomy classes at a nursing college and to develop an alternative instructional media instead of cadaver. Method: Four groups pretest-posttest experimental design were used. One hundred twenty students who attended an Anatomy lecture in September, 2009 were selected After attending the anatomy lecture, the subjects were divided into four group (30 for each group) conveniently. The heart anatomy knowledge level were measured by a self evaluation questionnaire and quiz before and after a different instructional media being applied for each group including making heart shape using colored clay, taking picture of a real heart, sketching the heart model with color pencil and drawing heart presented in the anatomy textbook. Data was analyzed by t-test, ANNOVA test using the SPSS/PC WIN 12 version. Result: A statistically significant differences in the level of heart anatomy knowledge acquirement was noted after four different instructional media being applied, and four different instructional media was effective to the anatomy practice education. However, no difference in statistical post test results was noted among the four groups. Conclusion: It is recommended that further comparative studies on the learning effect between human cadaver practice and different instructional media is necessary.

• The Korean Journal of Applied Statistics
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• v.23 no.6
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• pp.1057-1065
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• 2010

In this paper we discuss some cautionary notes in using the Pearson chi-squared test statistic for the goodness-of-fit of the ordinal response model. If a model includes continuous type explanatory variables, the resulting table from the t of a model is not a regular one in the sense that the cell boundaries are not fixed but randomly determined by some other criteria. The chi-squared statistic from this kind of table does not have a limiting chi-square distribution in general and we need to be very cautious of the use of a chi-squared type goodness-of-t test. We also study the limiting distribution of the chi-squared type statistic for testing the goodness-of-t of cumulative logit models with ordinal responses. The regularity conditions necessary to the limiting distribution will be reformulated in the framework of the cumulative logit model by modifying those of Moore and Spruill (1975). Due to the complex limiting distribution, a parametric bootstrap testing procedure is a good alternative and we explained the suggested method through a practical example of an ordinal response dataset.

• Proceedings of the Korean Society of Marine Engineers Conference
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• 2006.06a
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• pp.271-272
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• 2006

Zinc confers high corrosion resistance by acting as a sacrificial anode, and a zinc coating improves the appearance of steel. Chromate conversion coating (CCC) films are still one of the most efficient surface treatments for steel. Although such films can self-repair via the dissolution of Cr(VI), dissolved Cr(VI) have adverse effects on humans, and the environment. Therefore, we examined the corrosion protection property and morphology of colloidal silica conversion films as an alternative to CCC films. The corrosion behavior was investigated in 3% NaCl solution using electrochemical techniques, including electrochemical impedance spectroscopy, open circuit potential, and the salt spray test(SST). Corrosion was implied by the appearance of red rust on the specimen surface. In corrosion resistance at 3% NaCl solution, red rust appeared at 15-20, 55-70, and 83-98 days on Zn-electroplated steel, colloidal silica conversion-coated specimens, and CCC-coated specimens, respectively. In the salt spray test, the colloidal silica film provided better corrosion protection than CCC films, i.e., red rust appeared at 96 hours on the Zn-electroplated steel sheet, at 432 hours with the CCC films, and at 888 hours with silica conversion coating.

• Proceedings of the KIEE Conference
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• 1999.07e
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• pp.2326-2328
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• 1999

Developments of effective and economic diagnostic apparatus for industrial plastic insulated high voltage power cables are in discontented condition still. Some report told that DC high voltage was damaged plastic insulation of a partially aged power cable to lead breakdown easily. But now, we have no alternative tools of DC diagnostic apparatus, and we try to reduce a possibility of hazard DC diagnosis. DC diagnostic apparatus still have many advantages to field cable engineer like low price, portability easy applications and sufficient data. Main hazard of DC diagnosis is excessive hight of applied voltage Recent developments for DC diagnosis use considerably low voltage. But new test methods need special measuring device and manipulator, like high input impedance voltmeter, low leakage current high voltage switches, etc. So that reason, new DC diagnostic devices are normally very expensive and have low efficiency, economically. We try to design a composite test device for 3$\sim$4 newly developed method, have economical benefit th industrial engineer.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.8 no.3
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• pp.423-436
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• 1996

Thermodynamic performance of eight zeotropic R-22 alternative refrigerant mixtures selected by AREP(R-22 Alternative Refrigerants Evaluation Program) and R-32/R-125/R-134a(23%/25%/52%), namely R-407C were evaluated by the "drop-in" simulation method. An existing air conditioner was selected and its design data were used for the simulation. "ARI Test A" air conditions were applied. The degree of vapor superheat at the compressor inlet fixed at $5^{\circ}C$ for all the mixtures. The results of the simulation were compared with those of R-22. COPs of all mixtures except for R-32/R-227ea(35%/65%) and R-32/R-125/R-134a(10%/70%/20%), were higher than that of R-22 by 2%~8%, while the capacities were all lower than that of R-22 by 13%~27%. COP of R-32/R-134a(40%/60%) was 2.4% higher but the capacity was 15% lower than those of R-22. In the case of R-32/R-134a(30%/70%), COP and capacity were 5.5% higher and 15% lower than those of R-22, respectively. Among the ternary mixtures, R-407C and R-32/R-125/R-134a(30%/10%/60%) showed the best performance. COP of R-407C was 2.4% higher than those of R-22 but the capacity was 15% lower.

• The Korean Journal of Applied Statistics
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• v.29 no.7
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• pp.1411-1419
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• 2016

Nonparametric procedures in randomized block design was proposed by Friedman (1937) as a general alternative. This method is used to find out the difference in treatment effect. It can cause a loss of inter block information using the ranking in each block. This paper proposed nonparametric procedures using an aligned method proposed by Hodges and Lehmann (1962) to reduce block information based on joint placement suggest by Jo and Kim (2013) in a randomized block design. We also compared the power of the test of the proposed procedures and established method through a Monte Carlo simulation.

• Proceedings of the KIEE Conference
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• 2007.10c
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• pp.217-219
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• 2007

With the wide spread of direct current(DC) electric railroads in Korea, the stray current or leakage currents from negative return rails become a pending problem to the safety of nearby underground Infrastructures. The most widely used mitigation method for this interference is the stray current drainage method, which connects the underground metallic structures to the rails with diodes (polarized drainage) or thyristor (forced drainage). This method, however, inherently possesses some drawbacks such as an increase of total leakage torrents from rails, expansion of interference zone, etc. In order to resolve these drawbacks, we developed a rapid potential-controled rectifier and applied to a depot area where stray current inference is very severe. The effect of this method was analyzed from the field tell data and we suggest this method can be an excellent alternative to the drainage-bond-based mitigation methods.

• Atmosphere
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• v.28 no.2
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• pp.211-222
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• 2018

Cloud droplet activation process is well described by $K{\ddot{o}}hler$ theory and several parameterizations based on $K{\ddot{o}}hler$ theory are used in a wide range of models to represent this process. Here, we test the two different method of calculating the solute effect in the $K{\ddot{o}}hler$ equation, i.e., osmotic coefficient method (OSM) and ${\kappa}-K{\ddot{o}}hler$ method (KK). To do that, each method is implemented in the cloud droplet activation parameterization module of WRF-CHEM (Weather Research and Forecasting model coupled with Chemistry) model. It is assumed that aerosols are composed of five major components (i.e., sulfate, organic matter, black carbon, mineral dust, and sea salt). Both methods calculate similar representative hygroscopicity parameter values of 0.2~0.3 over the land, and 0.6~0.7 over the ocean, which are close to estimated values in previous studies. Simulated precipitation, and meteorological variables (i.e., specific heat and temperature) show good agreement with reanalysis. Spatial patterns of precipitation and liquid water path from model results and satellite data show similarity in general, but on regional scale spatial patterns and intensity show some discrepancy. However, meteorological variables, precipitation, and liquid water path do not show significant differences between OSM and KK simulations. So we suggest that the relatively simple KK method can be a good alternative to the OSM method that requires various information of density, molecular weight and dissociation number of each individual species in calculating the solute effect.