• Title/Summary/Keyword: Alternative methods

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Mucosal incision-assisted biopsy versus endoscopic ultrasound-assisted tissue acquisition for subepithelial lesions: a systematic review and meta-analysis

  • Suprabhat Giri;Shivaraj Afzalpurkar;Sumaswi Angadi;Sridhar Sundaram
    • Clinical Endoscopy
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    • v.55 no.5
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    • pp.615-625
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    • 2022
  • Background/Aims: Mucosal incision-assisted biopsy (MIAB) for tissue acquisition (TA) from subepithelial lesions (SELs) is emerging as an alternative to endoscopic ultrasound (EUS)-guided TA. Only a limited number of studies compared the diagnostic utility of MIAB and EUS for upper gastrointestinal (GI) SELs; therefore, we conducted this systematic review and meta-analysis. Methods: A comprehensive literature search from January 2020 to January 2022 was performed to compare the diagnostic accuracy and safety of MIAB and EUS-guided TA for upper GI SELs. Results: Seven studies were included in this meta-analysis. The pooled technical success rate (risk ratio [RR], 0.96; 95% confidence interval [CI], 0.89-1.04) and procedural time (mean difference=-4.53 seconds; 95% CI, -22.38 to 13.31] were comparable between both the groups. The overall chance of obtaining a positive diagnostic yield was lower with EUS than with MIAB for all lesions (RR, 0.83; 95% CI, 0.71-0.98) but comparable when using a fine-needle biopsy needle (RR, 0.93; 95% CI, 0.83-1.04). The positive diagnostic yield of MIAB was higher for lesions <20 mm (RR, 0.75; 95% CI, 0.63-0.89). Six studies reported no adverse events. Conclusions: MIAB can be considered an effective alternative to EUS-guided TA for upper GI SELs without an increased risk of adverse events.

The library & information science research in Korea and ethnographic method (한국문헌정보학 연구와 문화기술적 방법)

  • 김정근;이용재
    • Journal of Korean Library and Information Science Society
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    • v.24
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    • pp.107-161
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    • 1996
  • This study aims at introducing 'ethnography' which is one of the most representative qualitative research methods into Library and Information Science research in Korea.. Ethnography, derived from anthropology, helps researchers to understand the whole and deep aspect of the research object. That is because the researcher puts himself into the life-world of the research object and observes it for a long time. Ethnography can be used as an alternative method to quantitative research methods. Until now, Library and Information Science research in Korea has used quantitative research methods in almost every case. From the 1980s so-called 'scientific methods' using hypotheses testing, have provided the major premise for research methodology in Library and Information Science of Korea. And the researchers have seen their research object(Korean Libraries) not in the native perspective but largely in the western(especially American) perspective. There is a need in Korea for more culturally relative research. So the desirability of introducing ethnography and other qualitative research methods into Library and Information Science research in Korea can be summarized as follows : I. Ethnography and other qualitative methods are needed for the researchers to overcome the limitation of quantitative methods which have formed the main methodological paradigm in Library and Information Science research in Korea. While those quantitative scientific methods can be a n.0, pplied to the social sciences, they are not adequate for the social sciences. It is because the research objects of the social sciences are human and social phenomena. II. It is needed that Library and Information Science research in Korea pay more attention to the speciality of Korean libraries. To do researches based on the viewpoint of cultural-relativism, researchers should consider the cultural context of Korean libraries. During the past years researchers in other social science fields in Korea, especially sociology and pedagogy, have gradually a n.0, pplied the methods of ethnography to their fields. These social scientists have attempted to escape from ethnocentrism, a problem which has greatly influenced past and present research methods. To get a holistic and in-depth understanding of Korean libraries on the present stage, and to solve their problems radically, it seems imperative that Library and Information Science research in Korea pay more attention to qualitative research methods such as ethnography.

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Screening of Plant Extracts and Identification of their Insecticidal Metabolites against Myzus persicae (복숭아혹진딧물 방제용 식물추출물 탐색 및 살충성분 구명)

  • Yang, Si young;Lim, Da jung;Kim, Yeo Hee;Kim, In Seon
    • Korean Journal of Environmental Agriculture
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    • v.37 no.2
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    • pp.125-134
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    • 2018
  • BACKGROUND: Green peach aphid (Myzus persicae) is an insect pest that significantly affects crop production. A number of pesticides have been used for aphid control, but their concerns on insect resistance and food safety have required alternative methods for pest management. In an effort to find for an alternative approach to aphid control, we screened plants extracts and examined their potentiality as insecticidal bio-resources. METHODS AND RESULTS: Two hundred and ninety eight plant extracts were examined for insecticidal activity against the aphid, and the best candidate among them was chosen for further study. The extracts from Cinnamomum camphora was determined to be the best candidate exhibiting insecticidal activity more than 60% at a level of $1,000{\mu}g/mL$. GC/MS analyses detected camphor, borneol, 4-terpineol, ${\alpha}$-terpineol and caryophyllene oxide as major compositions from the extracts obtained by hydrodistillation. Caryophyllene oxide exhibited the highest insecticidal activity with a $LC_{50}$ value of $237{\mu}g/mL$. Camphor lowered significantly the $LC_{50}$ value of caryophyllene oxide and increased largely its concentration in aphid, suggesting that camphor played a role in enhancing the insecticidal activity of caryophyllene oxide. CONCLUSION: This study suggested that camphor and caryophyllene oxide may be used as an insecticidal bio-resource for insect control against green peach aphid.

Feasibility of Hydraulic Fracturing for Securing Additional Saline Groundwater in the Land-based Aquaculture Farm (양식장 용수 추가 확보를 위한 수압파쇄 적용성 평가)

  • Lee, Byung Sun;Kim, Young In;Park, Hak Yun;Cho, Jung Hwan;Song, Sung-Ho
    • Journal of Soil and Groundwater Environment
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    • v.20 no.7
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    • pp.34-42
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    • 2015
  • Feasibility tests for the hydraulic fracturing were conducted in order to secure additional saline groundwater for irrigating to the land-based aquaculture farm. Two boreholes were placed to the aquaculture farm A and B, respectively. A hydraulic fracturing using single packer was applied to major fracture zones within two boreholes. To identify effects of hydraulic fracturing on securing additional saline groundwater, some selective methods including well logging methods, pumping tests, and groundwater quality analysis were commonly applied to the boreholes before and after the hydraulic fracturing. Enlarging/creating fracture zones, increasing water contents in bedrock near boreholes, and increasing transmissivity were observed after the hydraulic fracturing. Even though the hydraulic fracturing could be an alternative to secure additional saline groundwater to the land-based aquaculture farm, salinity of the groundwater did not meet optimal thresholds for each fingerling in two farms: Fresh submarine groundwater discharge flowed the more into borehole of the farm A that resulted in decreasing a salinity value. Increased saline groundwater quantity in the borehole of the farm B rarely affect to the salinity. Although salinity problem of groundwater limited its direct use for the farms, the mixing with seawater could be effectively used for the fingerlings during the early stage. A horizontal radial collector well placed in the alluvial layer could be an alternative for the farms as well.

Skin corrosion and irritation test of sunscreen nanoparticles using reconstructed 3D human skin model

  • Choi, Jonghye;Kim, Hyejin;Choi, Jinhee;Oh, Seung Min;Park, Jeonggue;Park, Kwangsik
    • Environmental Analysis Health and Toxicology
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    • v.29
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    • pp.4.1-4.10
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    • 2014
  • Objectives Effects of nanoparticles including zinc oxide nanoparticles, titanium oxide nanoparticles, and their mixtures on skin corrosion and irritation were investigated by using in vitro 3D human skin models ($KeraSkin^{TM}$) and the results were compared to those of an in vivo animal test. Methods Skin models were incubated with nanoparticles for a definite time period and cell viability was measured by the 3-(4, 5-dimethylthiazol-2-yl)-2.5-diphenyltetrazolium bromide method. Skin corrosion and irritation were identified by the decreased viability based on the pre-determined threshold. Results Cell viability after exposure to nanomaterial was not decreased to the pre-determined threshold level, which was 15% after 60 minutes exposure in corrosion test and 50% after 45 minutes exposure in the irritation test. IL-$1{\alpha}$ release and histopathological findings support the results of cell viability test. In vivo test using rabbits also showed non-corrosive and non-irritant results. Conclusions The findings provide the evidence that zinc oxide nanoparticles, titanium oxide nanoparticles and their mixture are 'non corrosive' and 'non-irritant' to the human skin by a globally harmonized classification system. In vivo test using animals can be replaced by an alternative in vitro test.

Adsorption Characteristics of Natural Powdered Oil Absorbent for Marine Oil Pollution (해양오염제거용 천연분말상 유흉착재의 흡착 특성에 관한 연구)

  • 김인수;이진석;김동근;고성정
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.7 no.1
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    • pp.7-14
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    • 2001
  • The amount of petroleum consumption has been Increased according to the industrialization and It leads to the increase of the possibility of marine oil pollution. In Korea, some countermeasures including oil skimmer, gelling agent and herding agent of oil have been used for the remediation of the pollution. However, most of them have lets of shortcomings in the application under in-situ condition, because they are sensitive to the situation such as geographical feature, the wind and the tide. In reported literature, the natural powdered oil absorbent which is made of peat moss is an effective mean to clean spilled oil from lake or coast. However, the peat moss is a natural resource which is only Produced from a specific cold weather are like Canada. This indicates that the alternative materials which is readily obtained from everywhere are needed for powdered oil absorbent. Therefore. in the study, same natural materials including pine leaves and straw are tested as the alternative materials for the absorbent. The raw materials were dried and treated by heat at various temperature during several Periods and then. shattered by a grain cracking machine. The oil sorption capacity of the prepared materials was compared according to the methods of heat treatment and their sizes. The proportion of hydrogen cyanide to combustion of the absorbents was measured to confirm their final disposal methods. The biodegradability test of the absorbents was carried our to evaluate possibility of a side pollution in the coast. In was found that the heat treatment of pine leaves enhanced the capacity of oil sorption and decreased the water sorption. The maximum oil sorption was observed for the material treated at 18$0^{\circ}C$for 60 min. The amount of hydrogen cyanide from the combustion were 0.09ml/g, 0.07ml/g for pine leaves and straw respectively meaning that the final disposal by combustion might be feasible. The amount or organic carbon extracted from pine leaves during 7 days was up to 0.015g organic carbon from one gram of pine leaves. but the degradation was as fast as for glucose. It is concluded that the pine leaves can be served as a good raw material for the powdered oil absorbent like peat moss.

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Alternative Sintering Technology of Printed Nanoparticles for Roll-to-Roll Process (롤투롤 인쇄공정 적용을 위한 차세대 나노입자 소결 기술)

  • Lee, Eun Kyung;Eun, Kyoungtae;Ahn, Young Seok;Kim, Yong Taek;Chon, Min-Woo;Choa, Sung-Hoon
    • Journal of the Microelectronics and Packaging Society
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    • v.21 no.4
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    • pp.15-24
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    • 2014
  • Recently, a variety of printing technologies, including ink jet, gravure, and roll-to-roll (R2R) printing, has generated intensive interest in the application of flexible and wearable electronic devices. However, the actual use of printing technique is much limited because the sintering process of the printed nanoparticle inks remains as a huge practical drawback. In the fabrication of the conductive metal film, a post-sintering process is required to achieve high conductivity of the printed film. The conventional thermal sintering takes considerable sintering times, and requires high temperatures. For application to flexible devices, the sintering temperature should be as low as possible to minimize the damage of polymer substrate. Several alternative sintering methods were suggested, such as laser, halogen lamp, infrared, plasma, ohmic, microwave, and etc. Eventually, the new sintering technique should be applicable to large area, R2R, and polymer substrate as well as low cost. This article reviews progress in recent technologies for several sintering methods. The advantages and disadvantages of each technology will be reviewed. Several issues for the application in R2R process are discussed.

Efforts to obtain better rice seedlings performance under nontidal swamp land agro-ecosystem in south Sumatra, Indonesia

  • Suwignyo, Rujito A.;Sakagami, J.;Ehara, H.;Sulaiman, F.;Hasmeda, M.
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.50-50
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    • 2017
  • Swampland is a potential alternative land to be used in various agricultural production activities in Indonesia, because Indonesia have 33.41 million hectares of swamp land that consists of 13.28 million hectares nontidal swamp and million hectares 20.13 tidal swamp. In the province of South Sumatra, because of unpredictable water level in the field before planting, farmers have been doing agronomic adaptation method through the delay time of transplanting and forced to apply more than one the nursery practice with the combination of a floating nursery method and a dry-bed nursery method. This study was aimed to (1) evaluate the seedling growth and tillering pattern of several popular Indonesian rice varieties, and (2) look for alternative technologies to get a better rice seedlings under two nursery methods in the nontidal swamp land. In the first experiment, the seedling growth characteristics of five rice varieties (Ciherang, Inpara 5, Inpara 9, Inpari 29, and Inpari 30) was evaluated by two methods of nursery, i.e. floating nursery and dry-bed nursery. In the second experiment, rice variety of Inpari 30 was treated with Zn seed priming and foliar fertilizer of 2,300 ppm N at the nursery stage. Those treatments were combined with the time of seedling under floating and dry-bed nursery. The results of the first experiment showed that of the five varieties tested, dry-bed nursery method showed better seedling growth than floating nursery. This was indicated by high leaf number, tiller number, tillers pattern, shoot-root ratio and relative growth rate. Ciherang and Inpari 30 showed high tiller number, and they had produced tertiary tiller in the sixth week of observation. Moreover, shorter period of floating and dry-bed nursery in combination with the treatment of Zn seed priming and spraying seedling with foliar fertilizer N could improve the growth of seedlings.

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Prediction of Cryptosporidium parvum Inactivation in Advanced Ozone Drinking Water Treatment with Lab Scale Experiments (실험실 규모 크립토스포리디움의 불활성화 실험을 통한 오존 고도정수처리 정수장에서 소독 효과 예측)

  • Cho, Min;Chung, Hyenmi;Kim, Reeho;Shon, Jinsik;Park, Sangjung;Yoon, Jeyong
    • Journal of Korean Society on Water Environment
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    • v.21 no.1
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    • pp.7-13
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    • 2005
  • With the appearance of pathogenic microorganisms, which were resistant to free chlorine, the significant attention to the necessity of powerful alternative disinfection methods such as ozone, chlorine dioxide, LTV irradiation to inactivating pathogens has been increased in water treatment. Among these alternative disinfection methods, ozone is well known as strong biocidal method and the usage of ozone is also increasing in Korea. However, in Korea, there has been no report on the quantitative study of Cryptosporidium parvum with ozone and its evaluation in advanced drinking water treatments. This study reports on the methodology for predicting the ozone inactivation of Cryptosporidium parvum by ozone disinfection in advanced drinking water treatment. The method is based on the fact that a specific inactivation level of microorganisms is achieved at a unique value of ozone exposures, independent of ozone dose and type of water, and quantitatively described by a delayed Chick-Watson model. The required values ${\bar{C}}T$ for 2 log inactivation of Cryptosporidium parvum was $6.0mg/L{\cdot}min$ and $15.5mg/L{\cdot}min$ at $20^{\circ}C$ and $5^{\circ}C$, respectively. From this obtained Cryptosporidium parvum inactivation curves and calculated ${\bar{C}}T$ values of advanced drinking water treatment water in Korea with FIA (Flow injection alaysis), we can predict that water treatment plant can achieve a 1.1~1.8 log inactivation and 0~0.4 log inactivation at $20^{\circ}C$ and $5^{\circ}C$, respectively. This methodology will be useful for drinking water treatment plants which intend to evaluate the disinfection efficiencies of their ozonation process without full scale test and direct experiments with Cryptosporidium parvum.

Suitability of Alternative Dispute Resolution for the Fashion Industry - Focused on Arbitration for the Fashion Industry - (패션산업의 대체적 분쟁해결제도 적합성 - 패션산업의 중재 제도 도입을 중심으로 -)

  • Lee, Jae-Kyoung
    • Journal of Arbitration Studies
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    • v.25 no.1
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    • pp.87-105
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    • 2015
  • Intellectual property law is slowly fighting to keep pace with the rapid growth of the fashion industry. Copyright and patent law have proven only minimally effective in fashion, even in the US and other top fashion nations, forcing designers and fashion companies to rely on their trademarks to protect their work. Litigating trademark disputes in the fashion industry presents a host of problems as witnessed in a recent Christian Louboutin case, leading the parties to resort to Alternative Dispute Resolution(ADR) and Online Dispute Resolution(ODR). ADR methods, especially arbitration, are increasingly emerging as substitutes to litigation. Using these methods, the fashion industry (CFDA in the US case) should sincerely consider a self-regulating program in which its members, both fashion designers and corporations alike, can resolve disputes in a manner mutually beneficial to all parties in order to preserve the industry's growth, solidarity, and esteem In particular, for the US fashion industry, the ongoing Innovative Design Protection and Privacy Prevention Act(IDPPPA) anti-counterfeit legislation could have caused a chilling effect against innovation. New designers with no name and less resources who could normally flourish producing inspired-by designs may find themselves subject to copyright infringement legislation since the IDPPPA may expand the protection of established designers and brands with more resources. This fear and its implication could be solved by the fashion industry itself since fashion experts know best how to handle these fast-paced issues arising in the field. Therefore, stakeholders in the fashion industry should commit to protecting innovation within fashion on a long-term basis by establishing a panel handling an ADR process. This can mitigate the uncertainty created by the IDPPPA or any other legislation from elsewhere, which could result in a shying away from experimentation with inspired-by designs.