• Title/Summary/Keyword: Alpha-beam

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In vitro and in vivo Biological Responses of Proton Irradiation from MC-50 Cyclotron

  • Jung, Uhee;Eom, Hyeon Soo;Jeong, Kwon;Park, Hae-Ran;Jo, Sung-Kee
    • Journal of Radiation Industry
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    • v.6 no.3
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    • pp.223-229
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    • 2012
  • In this study, we investigated the biological damage and stress responses induced by ion beam (proton beam) irradiation as a basis for the development of protective measures against space radiation. We examined the biological effects of proton beam produced by MC-50 cyclotron at KIRAMS on the cultured cells and mice. The proton beam energy used in this study was 34.9 MeV and the absorption dose rate for cells and mice were $0.509Gy\;sec^{-1}$ and $0.65Gy\;sec^{-1}$, respectively. The cell survival rates measured by plating efficiency showed the different sensitivity and dose-relationship between CHO cells and Balb/3T3 cells. HGPRT gene mutation frequency in Balb/3T3 was $15{\times}10^{-6}Gy^{-1}$, which was similar to the reported value of X-ray. When stress signaling proteins were examined in Balb/3T3 cells, $I{\kappa}B-{\alpha}$ decreased markedly whereas p53, phospho-p53, and Rb increased after proton beam irradiation, which implied that the stress signaling pathways were activated by proton beam irradiation. In addition, cellular senescence was induced in IMR-90 cells. In the experiments with C57BL/6 mouse, the immune cells (white blood cells, lymphocytes) in the peripheral blood were greatly reduced following proton beam irradiation whereas red blood cells and platelets showed relatively little change. These results can be utilized as basic data for studying the biological effects of proton beam using MC-50 cyclotron with respect to proton therapy research as well as space radiation research.

Natural Frequencies of Simply Supported Tapered Beams (단순지지 변단면보의 고유진동수 산정)

  • 안성기;김순철;이수곤
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 1999.04a
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    • pp.137-144
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    • 1999
  • The finite element method was adopted to find out the natural frequencies of a sinusoidally tapered beam with simply supported boundary conditions. The parameters considered in the numerical analysis are the taper parameter, $\alpha$ ($\alpha$=0.0, 0.1, ~ , 2.0) and the sectional property parameters, m and n [(m, n):(0, 2), (1, 3), (2, 4)]. It is generally known that the results of the numerical analysis corresponding to each pair of sectional property parameters, (m, n) are represented by second order polynominals of $\alpha$ . The coefficients of a in the polynominals are determined by using the regression technique, which reveals small m in most cases of given sectional property parameters (m, n).

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SPECTRAL DIAGNOSTICS OF THE ENERGETIC PARTICLES IN SOLAR FLARES

  • FANG C.;DING M. D.;HENOUX J. C.;GAN W. Q.
    • Journal of The Korean Astronomical Society
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    • v.29 no.spc1
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    • pp.295-298
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    • 1996
  • Non-LTE calculations, with the non-thermal ionization effects included, indicated that for electron bombardment, the H$\alpha$ line is widely broadened and shows a strong central reversal. Significant enhancements at the line wings of Ly$\alpha$ and Ly$\beta$ are also predicted at the beginning of the impulsive phase of flares. For the proton bombardment, no strong broadening and no large central reversal are expected. However, due to proton-hydrogen charge exchange, the enhancements at the red wings of Ly$\alpha$ and Ly$\beta$ lines at the early impulsive phase of flares are significant. Our results show that the electron beam can also in some cases generate visible and UV continuum emission in white-light flares. However, at the onset phase, a negative flare may appear within several seconds, due to the increase of the H- opacity. Another spectroscopic signature of energetic particles, i.e. the impact polarization of atomic lines, is also mentioned.

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A Study of Characteristics of lnxGa1-xP by Photoreflectance measurement (Photoreflectance 측정에 의한 InxGa1-xP의 특성 연구)

  • Kim D. L.;Yu J. I.
    • Laser Solutions
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    • v.8 no.3
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    • pp.5-10
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    • 2005
  • [ $InxGa_{1-x}P/GaAs$ ] structures were grown by chemical beam epitaxy(CBE), Pure phosphine($PH_3$) gases were used as group V sources. for the group III sources, TEGa, TmIn were used. $InxGa_{1-x}P$ epilayer was grown on SI-GaAs substrate and has a 1-${\mu}m$ thick. We have investigated the characteristics of $InxGa_{1-x}P$ by the photoreflectance(PR) spectroscopy, The PR spectrum of $InxGa_{1-x}P$ shows third-derivative feature whose Peaks Provide energy gap. The energy gap of $InxGa_{1-x}P$ has deduced composition x. From temperature dependance of PR spectra, temperature coefficient is $dEg/dT=-3.773{\times}10^{-4}$ eV/K, and Varshni coefficients $\alpha$ and $\beta$ values obtained $4{\times}10^4$ eV/K and 267 K respectively. Also, interaction $\alpha$B was 19.4 meV using the Bose-Einstein temperature relation, and $\Theta$ value related the average phonon frequency were 101.4 K. In particular, shoulder peak related to defects observed in PR signal that measured in temperature 82 K.

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Comparisons of Elasto-Fiber and Fiber & Bernoulli-Euler reinforced concrete beam-column elements

  • Karaton, Muhammet
    • Structural Engineering and Mechanics
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    • v.51 no.1
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    • pp.89-110
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    • 2014
  • In this study, two beam-column elements based on the Elasto-Fiber element theory for reinforced concrete (RC) element have been developed and compared with each other. The first element is based on Elasto Fiber Approach (EFA) was initially developed for steel structures and this theory was applied for RC element in there and the second element is called as Fiber & Bernoulli-Euler element approach (FBEA). In this element, Cubic Hermitian polynomials are used for obtaining stiffness matrix. The beams or columns element in both approaches are divided into a sub-element called the segment for obtaining element stiffness matrix. The internal freedoms of this segment are dynamically condensed to the external freedoms at the ends of the element by using a dynamic substructure technique. Thus, nonlinear dynamic analysis of high RC building can be obtained within short times. In addition to, external loads of the segment are assumed to be distributed along to element. Therefore, damages can be taken account of along to element and redistributions of the loading for solutions. Bossak-${\alpha}$ integration with predicted-corrected method is used for the nonlinear seismic analysis of RC frames. For numerical application, seismic damage analyses for a 4-story frame and an 8-story RC frame with soft-story are obtained to comparisons of RC element according to both approaches. Damages evaluation and propagation in the frame elements are studied and response quantities from obtained both approaches are investigated in the detail.

Laser-Induced Direct Copper Patterning Using Focused $Ar^+$ Laser Beam (집속 아르곤 이온 레이저 빔을 이용한 레이저 유도 직접 구리 패터닝)

  • Lee, Hong-Kyu;Lee, Kyoung-Cheol;Ahn, Min-Young;Lee, Cheon
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.13 no.11
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    • pp.969-975
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    • 2000
  • Laser direct writing of micro-patterned copper lines has been achieved by pyrolytic decomposition of copper formate films (Cu(HCOO)$_2$.4$H_2O$), as a metallo-organic precursor, using a focused CW Ar$^{+}$ laser beam (λ=514nm) on PCB boards and glass substrates. The linewidth and thickness of the lines wee investigated as a functin of laser power and scan speed. The profiles of the lines were measured by scanning electron microscope (SEM), surface profiler ($\alpha$-step) and atomic force measured by scanning electron microscope (SEM), surface profiler ($\alpha$-step) and atomic force microscopy (AFM). The electrical resistivities of the patterned lines were also investigated as a function of laser parameters using probe station and semiconductor analyzer. We compared resistivities of the patterned copper lines with these of the Cu bulk. Resistivities decreased due to changes in morphology and porosity of the deposit, which were about 3.8 $\mu$$\Omega$cm and 12$\mu$$\Omega$cm on PCB and glass substrates after annealing at 30$0^{\circ}C$ for 5 minutes.s.

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A Monochromatic Soft X-ray Generation from Femtosecond Laser-produced Plasma with Aluminum

  • Son, Joon-Gon;Hwang, Byung-Jun;Seo, Okkyun;Kim, Jae Myung;Noh, Do Young;Ko, Do-Kyeong
    • Journal of the Korean Physical Society
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    • v.73 no.12
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    • pp.1834-1839
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    • 2018
  • A tabletop ultrafast soft x-ray has been generated from the laser-produce plasma with a femtosecond pulsed Ti:Sapphire laser. The estimated total flux of Al $K{\alpha}$ is of $2.2{\times}10^9photons/sec$ in $4{\pi}$ radian and the parameters related to the optical performance were obtained. The tungsten/silicon multilayer, flat quartz and bent thallium acid phthalate (TLAP) crystal were used for monochromatization of soft x-ray to refine the aluminum $K{\alpha}$ radiation and compared the respective value of $E/{\Delta}E$. To estimate the size of the x-ray source beam generated by a fs laser, the approximation using the FWHM obtained from the x-ray beam scan near the focal point was discussed, and the size of the diameter was about $9.76{\mu}m$.

Development of Program for Relative Biological Effectiveness (RBE) Analysis of Particle Beam Therapy

  • Chung, Yoonsun;Ahn, Sang Hee;Choi, Changhoon;Park, Sohee
    • Progress in Medical Physics
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    • v.28 no.1
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    • pp.11-15
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    • 2017
  • Relative biological effectiveness (RBE) of particle beam needs to be evaluated at particle beam therapy centers before the clinical application of the particle beam. However, since RBE analysis is implemented manually, it is useful to have a tool that can easily and effectively handle the data of experiments to generate cell survival curve and to analyze RBE simultaneously. In this work, the development of a program for RBE analysis of particle beam therapy was presented. This RBE analysis program was developed to include two parts; fitting the cell survival curves to linear-quadratic model and calculating the RBE values at a certain endpoint using fitting results. This program was also developed to simultaneously compare and analyze the template results that stored experiment data with photon and particle beam irradiations. The results of the cell survival curve obtained by each irradiation can be analyzed by the user on a desired data after reading the template stored in the easy-to-use excel file. The analysis results include the cell survival curves with error range, which are appeared in the screen and the ${\alpha}$ and ${\beta}$ parameters of linear-quadratic model with 95% confidence intervals, RBE values, and $R^2$ values to evaluate goodness-of-fit of survival curves to model, which are stored in a text cvs file. This software can generate cell survival curve, fit to model, and calculate RBE all at once with raw experiment data, so it helps users to save time for data handling and to reduce the possibility of making error on analysis. As a coming plan, we will create a user-friendly graphical user interface to present the results more intuitively.

Suggesting double-web I-shaped columns for omitting continuity plates in a box-shaped column

  • Saffari, Hamed;Hedayat, Amir A.;Goharrizi, Nasrin Soltani
    • Steel and Composite Structures
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    • v.15 no.6
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    • pp.585-603
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    • 2013
  • Generally the required strength and stiffness of an I-shaped beam to the box-shaped column connection is achieved if continuity plates are welded to the column flanges from all sides. However, welding the forth edge of a continuity plate to the column flange may not be easily done and is normally accompanied by remarkable difficulties. This study was aimed to propose an alternative for box columns with continuity plates to diminish such problems. For this purpose a double-web I-shaped column was proposed. In this case the strength and rotational stiffness of the connection was provided by nearing the column webs to each other. Finite element studies on about 120 beam-column connections showed that the optimum proportion of the distance between two column webs and the width of the column flange (parameter ${\beta}$) was a function of the ratio of the beam flange width to the column flange width (parameter ${\alpha}$). Hence, based on the finite element results, an equation was proposed to estimate the optimum value of parameter ${\beta}$ in terms of parameter ${\alpha}$ to achieve the highest connection performance. Results also showed that the strength and ductility of post-Northridge connections of such columns are in average 12.5 % and 54% respectively higher than those of box-shaped columns with ordinary continuity plates. Therefore, a double-web I-shaped column of optimum arrangement might be a proper replacement for a box column with continuity plates when beams are rigidly attached to it.

A study on the deposition characteristics of the hi thin films deposited ionized cluster beam deposition (ICBD법으로 증착된 Al 박막의 증착특성 연구)

  • 안성덕;김동원;천성순;강상원
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.7 no.2
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    • pp.207-215
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    • 1997
  • Aluminum (Al) thin films were deposited on the Si(100) and TiN(60 nm)/Si (100) substrate by the ionized cluster beam deposition (ICBD) method. The characteristics of thin films were examined by the $\alpha$-step, four-point-probe, Scanning Electron Spectroscopy (SEM), Auger Electron Spectroscopy (AES). The growth rate of the Al thin film increased and the resistivity decreased as the crucible temperature increased. At the crucible temperature $1800^{\circ}C$, the microstructure of Al thin film deposited was smooth and continuous the resistivity decreased as the acceleration voltage increased. Also, the minimum resistivity in Si(100) substrate and TiN(60 nm)/Si(100) substrate were 3.4 $\mu \Omega \textrm {cm}$, 3.6 $\mu \Omega \textrm {cm}$ at the acceleration voltage 4 kV and 2 kV respectively. From the AES spectrumt 14 wasn't detected any impurities In the Al thin film. Therefore the resistivity of Al thin film was affected by the microstructure of film.

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