• Asian-Australasian Journal of Animal Sciences
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• v.31 no.2
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• pp.208-217
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• 2018

Objective: Examine the effects of supplementing bahiagrass hay (BG) with potentially anthelmintic quantities of hays of perennial peanut (PEA) or sericea lespedeza (LES) or seeds of velvet bean (Mucuna pruriens L.; MUC) or papaya (PAP) on the intake and nutritive value (Experiment 1), and the performance and parasite burden (Experiment 2) of goats. Methods: In Experiment 1, 38 male goats ($27.4{\pm}5.7kg$ body weight) were randomly assigned to each of 5 treatments: i) BG alone and BG plus; ii) PEA; iii) LES; iv) MUC; and v) PAP. Goats were fed for ad libitum consumption and adapted to the diets for 14 d followed by 7 d of measurement. The PEA, LES, MUC (50%, 50%, and 10% of the diet dry matter [DM], respectively), and PAP (forced-fed at 10 g/d) were fed at rates that would elicit anthelmintic effects. In Experiment 2, goats remained in the same treatments but were allocated to 15 pens (3 pens per treatment) from d 22 to 63. All goats were infected with parasites by grazing an infected bahiagrass pasture from 0800 to 1500 h daily and then returned to the pens. Results: Dry matter intake tended to be greater in goats fed PEA and LES than those fed BG (757 and 745 vs 612 g/d, respectively). Digestibility of DM (59.5% vs 54.9%) and organic matter (60.8% vs 56.0%) were greater in goats fed MUC vs BG, respectively. In Experiment 2, feeding PAP, LES, and PEA to goats reduced nematode fecal egg counts by 72%, 52%, and 32%, reduced abomasal adult worm counts by 78%, 52%, and 42%, and decreased plasma haptoglobin concentrations by 42%, 40%, and 45% relative to feeding BG alone, respectively. Conclusion: Supplementation with PEA, LES, and PAP decreased the parasite burden of goats but did not increase their performance. PAP was the most effective anthelmintic supplement.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.1
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• pp.73-79
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• 2004

The objective of the present study was to determine whether ${\beta}$1-4 galacto-oligosaccharides (GOS) and Candida kefyr combined with nitrate as manipulators could suppress rumen methanogenesis without nitrate poisoning in sheep. Four rumen fistulated wethers were allocated to a $4{\times}4$ Latin square design. Nitrate (1.3 g $NaNO_3$ $Kg^{-0.75}$body weight) with and without GOS and Candida kefyr were administered into the rumen through fistula as a single dose 30 min after the morning meal. GOS and Candida kefyr were supplemented by sprinkling onto the feed and through rumen fistula, respectively. The four treatments consisted of saline, nitrate, nitrate plus GOS and nitrate plus GOS plus Candida kefyr. Physiological saline was used as the control treatment. Compared to saline treatment, the administration of nitrate alone resulted in a very marked decrease in rumen methanogenesis and an increase in rumen and plasma nitrite production and blood methaemoglobin formation consequently causing a decline in oxygen consumption, carbon dioxide production and metabolic rate. When compared to nitrate alone, the simultaneous administration of nitrate with GOS decreased nitrite accumulation in rumen and plasma and nitrate-induced methaemoglobin, while retaining low methane production. However, GOS could not fully restore metabolic parameters reduced by nitrate. When compared to the simultaneous administration of nitrate with GOS, the simultaneous administration of nitrate with GOS plus Candida kefyr lowered rumen methanogenesis to a negligible level, but did not decrease rumen and plasma nitrite accumulation as well as blood methaemoglobin formation. Thus, these results suggest that combination of nitrate with GOS may be a potent manipulator to suppress rumen methanogenesis with abating the hazards of nitratenitrite toxicity in ruminants.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.7
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• pp.4668-4678
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• 2015

This study was conducted to determine the correlation between breakfast consumption and health-related quality of life in elderly adults. It analyzed the data from the National Health and Nutrition Examination Survey from 2010 to 2012, using a sample of 4,035 people aged 65 or above. Analysis followed the SAS SURVEY procedure, considering the complex sample design. A t-test, a chi-square test, and logistic regression analysis were performed using SAS version 9.3. The rate of skipping breakfast by elderly adults was 4.7%, and it was higher in women and elderly adults living alone. It also significantly differed by drinking status and BMI. Elderly adults consuming breakfast had slightly higher scores on the health-related quality of life measure than those who did not (0.85 vs 0.81). Results revealed that health-related quality of life increased with meal frequency, and that elderly adults who ate breakfast tended to score better on the pain/discomfort and anxiety/depression domains of the health-related quality of life measure. It was found that breakfast consumption associated with health-related quality of life in elderly adults. Accordingly, it is necessary to increase awareness among elderly adults regarding the importance of breakfast, and to improve their health-related quality of life by developing and implementing interventions to improve dietary habits.

• Korean Journal of Veterinary Research
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• v.41 no.4
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• pp.549-555
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• 2001

Indole-3-carbinol (I3C), one component of cruciferous vegetables (the Fammily of Cruciferae), has been shown to exert its chemopreventive effect in liver, colon and mammary tissue before or concurrent exposure of carcinogen, but there have been several evidences that consumption of I3C induced tumor promotion in some tissues. Our studies were investigated to examine the modifying effects of I3C in the 7,12-dimethylbenz[$\alpha$]anthracene (DMBA) induced rat mammary gland tumor model. Fifty-two female Sprague-Dawley rats were randomly divided into five groups. Animals of the group 1 were given the diet containing 100ppm I3C and animals of the groups 2 and 4 were given the diet containing 300ppm I3C from 6 weeks of age. At 7 weeks of age, the animals of the groups 1, 2 and 3 were intubated with DMBA. All amimals were killed at 20 weeks after carcinogen treatment. There were significant increases of food consumption in I3C feeding groups compared with those of basal diet feeding groups. The incidences of the mammary tumors in the group 1, 2 and 3 were 75.0% (9/12), 56.3% (9/16) and 93.8% (15/16), respectively and the average number of tumors of group 1 (DMBA+I3C 100ppm: $2.08{\pm}0.61$) and 2 (DMBA+I3C 300ppm: $1.19{\pm}0.32$) were significantly lower than that of group 3 (DMBA alone: $4.63{\pm}0.72$) at the value of P<0.05 and P<0.001, respectively. In the pathological examination of appearing tumors, most of them were adenocarcinoma. Many epithelial cells of tumors showed strong estrogen receptor (ER) $\alpha$ expression but there were slight difference of ER $\alpha$ expression among the type of tumors. We suggest that pre-initiation treatment of I3C has an inhibitory effects on mammary carcinogenesis induced by DMBA.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.1
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• pp.39-45
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• 2004

Despite higher fecundity, Black Bengal goat generally has lower milk production, which is often insufficient for their multiple kids. However, milk requirement of Black Bengal kids is poorly defined. Present trial was thus designed to determine the requirement and intake of milk of pre-weaned Black Bengal kids in relation to their growth rate age and sex. Thirty, one month old Black Bengal kids of either sex divided into two groups were allocated to two groups, suckling alone (T1) or suckling along with teat-bottle feeding of milk (T2). Ten kids were allocated for the T1 and 20 kids were allocated for the T2. Digestibility of milk was also determined in T2 animals. Average daily consumption of milk, milk energy and milk N were 773 and 722 g, 1,170 and 1,093 kJ/kg $W^{0.75}/d$ and 1,552 and 1,462 mg N/kg $W^{0.75}/d$, respectively. During 9 weeks trial period, male kids had significantly higher live weight (4.32 vs. 4.20 kg; p<0.01) and intake of milk (773 vs. 722 g/d; p<0.05), energy (117 vs. 1,093 kJ/kg $W^{0.75}$/d; p<0.01) and N (1,552 vs.1,462 mg/k $W^{0.75}/d$; p<0.01) than the female. Milk consumption and the corresponding milk energy and milk N intake increased linearly up to 5th week of the trial, which, then decreased quadratically up to 9th week i.e., up to the weaning. Overall milk DM intake during this period was 2.58% (range 1.5-3.0%) of live weight or about 36 g/kg $W^{0.75}/d$ (range 29-45 g/kg $W^{0.75}/d$). Pre-weaned Black Bengal kids of about 4.5 kg weight, growing at the rate of 60 g weight daily requires at least 750 g milk daily. Daily live weight gain, estimated as the regression between the live weights over time, was 60 g ($r^2$=0.99) and 55 g ($r^2$=0.99), respectively, for the male and female kids. Efficiency of milk energy utilization for weight gain ranged from 0.67 to 0.84 (mean 0.81) for the male kid and 0.75 to 0.91 (mean 0.82) for the female kids. Efficiency of milk protein utilization for weight gain ranged from 0.46 to 0.70 (mean 0.61) for the male kid and 0.51 to 0.81 (mean 0.64) for the female kids. Additional teat-bottle feeding of suckling kids had no significant effect on their growth rate (54vs. 57 g/d). Average digestibility of milk DM, OM and N was 98.85, 98.99 and 98.69%, respectively and they were slightly (p>0.05) higher in the male than the female kids. Results suggest that the requirement of energy and protein and their utilization efficiency in Black Bengal kids is not different from that of the other breeds of goat.

• The Korean Journal of Pain
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• v.29 no.2
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• pp.110-118
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• 2016

Background: Nefopam is a non-opioid, non-steroidal, centrally acting analgesic drug. The concomitant use of opioids and nefopam is believed to have many advantages over the administration of opioids alone for postoperative pain management. We conducted a randomized, double-blind study to determine the fentanyl-sparing effect of co-administration of nefopam with fentanyl for postoperative pain management via patient controlled analgesia (PCA). Methods: Ninety female patients who underwent laparoscopic total hysterectomy under general anesthesia were randomized into 3 groups, Group A, fentanyl $1,000{\mu}g$; Group B, fentanyl $500{\mu}g$ + nefopam 200 mg; and Group C, fentanyl $500{\mu}g$ + nefopam 400 mg, in a total volume of 100 ml PCA to be administered over the first 48 h postoperatively without basal infusion. The primary outcome was total fentanyl consumption during 48 h; secondary outcomes included pain scores and incidence of side effects. Results: Eighty-one patients were included in the analysis. The overall fentanyl-sparing effects of PCA with concomitant administration of nefopam during the first 48 h postoperatively were 54.5% in Group B and 48.9% group C. Fentanyl use was not significantly different between Groups B and C despite the difference in the nefopam dose. There were no differences among the three groups in terms of PCA-related side effects, although the overall sedation score of Group B was significantly lower than that of Group A. Conclusions: The concomitant administration of nefopam with fentanyl for postoperative pain management may allow reduction of fentanyl dose, thereby reducing the risk of opioid-related adverse effects.

• The Korean Journal of Pain
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• v.13 no.2
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• pp.218-223
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• 2000

Background: This study was conducted to evaluate the efficacy of a parenteral nonsteroidal anti-inflammatory agent for management of post-surgical pain and its effect on hospital stay and long-term surgical outcome. Methods: Total of 40 patients undergoing lumbar discectomy were randomly assigned to two groups, receiving either 1) 30 mg intravenous ketorolac upon surgical closure, every 6 hours for 36 hours, and morphine IV PCA (intravenous patient controlled analgesia), or 2) only morphine PCA. A blinded investigator recorded; the visual analog pain scores, total postoperative narcotic consumption, complications by morphine PCA, length of hospitalization (from surgery to discharge), and long-term outcome at 6 weeks. Results: The patients who received IV ketorolac and morphine PCA reported significantly lower visual analog pain scores than patients receiving only morphine PCA. Cumulative morphine doses were significantly lower in the ketorolac group (P<0.001). There was no significant difference between groups in the frequency of side effects related to morphine PCA. Mean length of hospitalization was longer for patients receiving only morphine PCA, but there was no statistical significance. Six weeks after surgery, four (20.0%) patients who received only morphine PCA suffered persistent back pain. In contrary, all those patients who received ketorolac were free of back pain at follow-up (P<0.05). Conclusions: These results suggest that intermittent IV bolus ketorolac, when used with opioid IV PCA is more effective than opioid IV PCA alone for postoperative pain following lumbar disc surgery. However, this strategy did not contribute to early discharge from hospital after lumbar disc surgery. The effect to long-term surgical outcome was not conclusive.

• Nutrition Research and Practice
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• v.7 no.1
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• pp.59-65
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• 2013

Excessive sodium intake leading to hypertension, stroke, and stomach cancer is mainly caused by excess use of salt in cooking. This study was performed to estimate the salt content in school meals and to compare differences in perceptions related to sodium intake between students and staffs working for school meal service. We collected 382 dishes for food from 24 schools (9 elementary, 7 middle, 8 high schools) in Gyeonggi-do and salt content was calculated from salinity and weight of individual food. The average salt content from elementary, middle, and high school meals were 2.44 g, 3.96 g, and 5.87 g, respectively. The amount of salt provided from the school lunch alone was over 80% of the recommended daily salt intake by WHO. Noodles, stews, sauces, and soups were major sources of salt intake at dish group level, while the most salty dishes were sauces, kimchies, and stir-fried foods. Dietary knowledge and attitude related to sodium intake and consumption frequency of the salty dishes were surveyed with questionnaire in 798 students and 256 staffs working for school meal service. Compared with the staffs, the students perceived school meals salty and the proportions of students who thought school meals were salty increased with going up from elementary to high schools (P < 0.001). Among the students, middle and high school students showed significant propensity for the preference to one-dish meal, processed foods, eating much broth and dipping sauce or seasoning compared with the elementary students, although they had higher nutrition knowledge scores. These results proposed that monitoring salt content of school meals and consideration on the contents and education methods in school are needed to lower sodium intake.

• Asian Journal of Atmospheric Environment
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• v.9 no.4
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• pp.288-297
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• 2015

In this study, wind conditions and its energy potential have been assessed by conducting a Weibull analysis of the wind speed data (over the period of 2002-2011) measured from a port city (Mongla) and an isolated island (Sandwip) in Bangladesh. The monthly mean wind speed at Mongla ranged from 1.60 m/s (December) to 2.47 m/s (April). The monthly values of Weibull shape parameter (k) were from 1.27 to 2.53. In addition, the values of the scale parameter (c) and the monthly wind power density ranged from 1.76 to 2.79 m/s and 3.95 to $17.45W/m^2$, respectively. The seasonal mean wind speed data varied from 1.72 (fall) to 2.29 m/s (spring) with the wind power density from 5.33 (fall) to $14.26W/m^2$ (spring). In the case of Sandwip, the results were comparable to those of Mongla, but moderate reductions in all the comparable variables were observed. The wind data results of these two areas have been compared with those of eight other locations in the world with respect to wind power generation scale. According to this comparison, the wind power generation scale for Mongla and Sandwip was adequate for stand-alone small/micro-scale applications such as local household consumption, solar-wind hybrid irrigation pumps, and battery charging.

• Journal of Microbiology and Biotechnology
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• v.25 no.6
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• pp.893-902
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• 2015

Various Lactobacillus reuteri strains were screened for the ability to convert glycerol to 1,3-propanediol (1,3-PDO) in a glycerol-glucose co-fermentation. Only L. reuteri DSM 20016, a well-known probiotic, was able to efficiently carry out this bioconversion. Several process strategies were employed to improve this process. Co²⁺ addition to the fermentation medium, led to a high product titer (46 g/l) of 1,3-PDO and to improved biomass synthesis. L. reuteri DSM 20016 produced also ca. 3 µg/g of cell dry weight of vitamin B₁₂, conferring an economic value to the biomass produced in the process. Incidentally, we found that L. reuteri displays the highest resistance to Co²⁺ ions ever reported for a microorganism. Two waste materials (crude glycerol from biodiesel industry and spruce hydrolysate from paper industry) alone or in combination were used as feedstocks for the production of 1,3-PDO by L. reuteri DSM 20016. Crude glycerol was efficiently converted into 1,3-PDO although with a lower titer than pure glycerol (33.3 vs. 40.7 g/l). Compared with the fermentation carried out with pure substrates, the 1,3-PDO produced was significantly lower (40.7 vs. 24.2 g/l) using cellulosic hydrolysate and crude glycerol, but strong increases of the maximal biomass produced (2.9 vs 4.3 g/l CDW) and of the glucose consumption rate were found. The results of this study lay the foundation for further investigations to exploit the biotechnological potential of L. reuteri DSM 20016 to produce 1,3-PDO and vitamin B₁₂ using industry byproducts.